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Effect and Safety of Penetrating Moxibustion in Treatment of Migraine without Aura:A Randomized Controlled Trial

Chinese Journal of Integrative Medicine 2021年第12期27卷 927-932页

作者： GAO Ling xiE Jin LI xiao GUO Ya-jing ZHANG Ming-ming MENG Ling-yan LIN Qian-ting GAO xi-yan College of Acupuncture and Tuina Henan University of Chinese MedicineZhengzhou(450008)China Acupuncture Clinic of the Third Affiliated Hospital of Henan University of Chinese Medicine Zhengzhou(450008)China College of Acupuncture and Tuina Shanghai University of Traditional Chinese MedicineShanghai(201203)China

Objective To observe the clinical effect of penetrating moxibustion on migraine without aura(MO)*** Totally 60 MO patients from the Acupuncture Clinic of the Third Affiliated Hospital of Henan University of Chinese Medicine were collected from November 2015 to February *** patients were assigned to a treatment group and a control group using a random number table,30 cases in each *** treatment group was treated with penetrating moxibustion,and the control group was treated with mild moxibustion,thrice a week for 4 consecutive *** total effective rate,Visual Analogue Scale(VAS)scores,headache intensity,and Migraine Specific Quality of Life Questionnaire(MSQ)scores of patients after treatment were compared between the two *** moxibustion sensation and reaction after moxibustion were observed,and the adverse reactions were *** patients were followed up at 4 and 16 weeks after *** The total effective rate of the treatment group was significantly higher than that of the control group(93.33%vs.80.00%,Pxibustion sensations of itching,numbness and cold as well as flushing and sweating after moxibustion in the treatment group was all significantly higher than that in the control group(P0.05).Conclusions Penetrating moxibustion can significantly relieve pain and improve quality of life of MO *** penetrating moxibustion,flushing and sweating of patients were obvious,and the curative effect was superior to the mild moxibustion.

关键词： penetrating moxibustion randomized controlled trial migraine without aura Chinese medicine

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Evolutionary and functional analyses of the interaction between the Bombyx mori inhibitor of apoptosis(IAP)and nucleopolyhedrovirus IAPs

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Insect Science 2020年第3期27卷 463-474页

作者： Peng Chen Tao-Tao Kang xi-yan Bao Zhan-Qi Dong yan Zhu Wen-Fu xiao Min-Hui Pan Cheng Lu State Key Laboratory of Silkworm Genome Biology Southwest UniversityChongqingChina Key Laboratory of Sericultural Biology and Genetic Breeding Ministry of AgricultureSouthwest UniversityChongqingChina

As an important insect immune response,apoptosis plays a critical role in the interaction between baculoviruses and insect *** reports have identified inhibitor of apoptosis(IAP)proteins in both insects and baculoviruses,but the relationship between these proteins is still not clearly ***,we found that insect IAP proteins were clustered with baculovirus IAP3,suggesting that the baculovirus iap3 gene might be derived from the Lepidoptera or *** demonstrated that Bombyx mori inhibitor of apoptosis(Bmiap)gene had an inhibitory effect on apoptosis in silkworm *** analysis of the effects of Bmiap genes on the proliferation of *** nucleopolyhedrovirus(BmNPV)showed that both the Bmiap and BmNPV iap genes increased BmNPV proliferation after BmNPV infected silkworm *** results also indicated that BmNPV IAP1 and IAP2 directly interacted with BmIAP in silkworm cells,implying that the Bmiap gene might be hijacked by BmNPV iap genes during BmNPV *** together,our results provide important insights into the functional relationships of iap genes,and improve our knowledge of apoptosis in baculoviruses and insect hosts.

关键词： baculovirus baculovirus-host interaction BmNPV Bombyx mori evolution inhibitor of apoptosis

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The epidermal immune microenvironment plays a dominant role in psoriasis development,as revealed by mass cytometry

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Cellular & Molecular Immunology 2022年第12期19卷 1400-1413页

作者： Yuan Zhou Fan Xu Xue-yan Chen Bing-xi yan Zhao-Yuan Wang Si-Qi Chen Min Zheng xiao-Yong Man Department of Dermatology Second Affiliated HospitalZhejiang University School of MedicineHangzhouChina

Psoriasis is a common chronic inflammatory skin *** diversity and heterogeneity of immune cells in human skin have been studied in recent years,but the spatial distribution of immune cells at the single-cell level in the human psoriatic epidermis and dermis remains *** this study,we mapped psoriatic skin immune cells from paired lesional,perilesional,and nonlesional skin samples using mass *** dendritic cells(DCs)were found in the psoriatic epidermis and *** dermal CD1c^(+)CD11b^(+)cDC2s migrated to the epidermis in the perilesional skin during the preinitiation ***1c^(+)CD11b^(+)cDC2s rapidly replaced EpCAM^(+)CD11c^(low) LC cells and initiated ***,CD207^(+)CD11c^(hi) LC and CD5^(+)T cells accumulated in the psoriatic epidermis and orchestrated epidermal inflammation in *** immune cell pool in the psoriatic dermis primarily included APCs and T ***,unlike that in the dermis,the epidermal immune environment was more significant and coincided with the inflammation occurring during psoriasis.

关键词： Psoriasis Cutaneous immune Mass cytometry Dendritic cell

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Engineering intermolecular charge transfer in chiral organometallic crystals by rational doping for high-contrast CPL switches

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Science China Chemistry 2023年第7期66卷 2011-2018页

作者： Ying-Jie Liu Liang Chen Zhao-yang Wang xi-yan Dong Ya-Ke Li Shuang-Quan Zang Henan Key Laboratory of Crystalline Molecular Functional Materials Henan International Joint Laboratory of Tumor Theranostical Cluster MaterialsGreen Catalysis Center and College of ChemistryZhengzhou UniversityZhengzhou 450001China College of Chemistry and Chemical Engineering Henan Polytechnic UniversityJiaozuo 454003China

The development of circularly polarized luminescence(CPL)switches is of great importance but ***,a charge donor/acceptor pair comprising two chiral gold(I)-isocyanide complexes was designed to construct light-harvesting system via intermolecular charge-transfer(CT)*** doping nonemissive S-Au I into blue-emitting S-AuCN,(S-Au CN)_(1-x)(S-AuI)_(x)(0≤x≤3.4%)with tunable emission from blue to red was *** large red-shifted emission was realized based on the remarkable change of the electronic properties between the S-Au CN dimer and red-emitting(S-A CN)-(S-AuI)CT pair,and the resulting energy-transfer(En T)process between ***,the En T process can be switched off/on by external stimuli of grinding and CH_(2)Cl_(2)fuming,giving rise to high-contrast(blue versus red)CPL switching *** study opens a novel avenue for developing CPL switches by constructing light-harvesting CT-doped systems based on chiral organometallic complexes.

关键词： charge transfer energy transfer crystal engineering circularly polarized luminescence gold complex

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Numerical simulation of rock-breaking and influence laws of dynamic load parameters during axial-torsional coupled impact drilling with a single PDC cutter

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Petroleum Science 2023年第3期20卷 1806-1827页

作者： yan xi Hao-Yu Wang Chun-Qing Zha Jun Li Gong-Hui Liu Bo-Yun Guo Beijing University of Technology Bejing100124China China University of Petroleum-Bejing Beijing102249China China University of Petroleum-Beijing at Karamay KaramayXinjiang834000China University of Louisiana at Lafayett Lafayette70504USA

Axial and torsional impact drilling technology is used to improve the drilling efficiency of hard rock formation in the deep ***,the corresponding theory is not mature,and there are few correlative research reports on the rock-breaking mechanism of axial and torsional coupled impact drilling *** the influence of the impact hammer geometry and movement on the dynamic load parameters(i.e.,wavelength,amplitude,frequency,and phase difference),a numerical model that includes a hard formation and single polycrystalline diamond compact cutter was *** Riedel-Hiermaier-Thoma model,which considers the dynamic damage and strength behavior of rocks,was adopted to analyze the rock damage under axial and torsional impact *** numerical simu-lation results were verified by the experimental *** was found that compared with conventional drilling,the penetration depths of axial,torsional,and axial-torsional coupled impact drilling increased by 31.3%,5.6%,and 34.7%,*** the wavelength and amplitude of the axial impact stress wave improved the penetration *** the bit rotation speed remained unchanged,increasing the frequency in the axial and circumferential directions had little effect on the penetration ***,as the frequency increased,the cutting surface became increasingly smooth,which reduced the occurrence of bit *** the phase difference between the axial and circumfer-ential stress waves was 25%,the penetration depth significantly *** addition,the bit vibration problem can be effectively ***,the adjustment of engineering and tool structure parameters is proposed to optimize the efficiency of the axial-torsional coupled impact drilling tool.

关键词： Axial-torsional coupled impact drilling tool Rock-breaking PDC cutter RHT model

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Systematic Synthesis on Pathological Models of CCCII and Modified CCCII

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Journal of Electronic Science and Technology 2018年第2期16卷 163-168页

作者： Yong-An Li yan-Hua xi Zhan-Ting Fan Yu-Ye Zhang Ji-xia Wu School of Physics and Electronic Engineering Xianyang Normal UniversityXianyang 712000

According to the equivalent view for the terminal current-voltage constraint relationship between pathological elements and the various second-generation current-controlled convegors （CCCIIs）, four patholo- gical models for the CCCII are first derived by means of the nodal admittance matrix expansion in this paper. Moreover, 48 new pathological models for the modified CCCII are also synthesized. The derived pathological models for the various CCCIIs are expected to be useful in circuit analysis and synthesis.

关键词： Modified second-generation currentcontrolled conveyor pathological elements secondgeneration current-controlled conveyor systematic synthesis

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Effects of different regional cerebral blood flow on white matter hyperintensity in CADASIL patients

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The Journal of Biomedical Research 2022年第5期36卷 368-374页

作者： Runrun Wang Jiewen Zhang Junkui Shang Fengyu Wang xi yan Department of Neurology Henan Provincial People's HospitalZhengzhou University People's HospitalHenan University People's HospitalZhengzhouHenan 450003China

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy(CADASIL)is an early-onset inherited small vessel *** cerebral blood flow(CBF)may contribute to white matter hyperintensity(WMH)severity in CADASIL,but more evidence is needed to support this *** study comprised six patients with CADASIL who harbored mutations in the coding sequence of NOTCH3 and twelve age-matched neurologically healthy *** collected clinical and imaging data from patients with CADASIL and divided the brain into four regions:WMH,normal-appearing white matter(NAWM),gray matter(GM),and global *** analyzed the relationship between CBF of each region and the WMH *** with the control group,CBF was significantly decreased in all four regions in the CADASIL *** CBF in these regions was correlated with higher WMH volume in *** in the NAWM,GM and global regions was positively correlated with that in WMH ***,after correction tests,only CBF in the WMH region but not in NAWM,GM and global regions was associated with WMH *** findings suggest that CBF in the WMH region is an influencing factor of the WMH severity in CADASIL.

关键词： cerebral hypoperfusion neurovascular unit white matter hyperintensity small vessel disease CADASIL

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Abnormal activity detection for surveillance video synopsis

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High Technology Letters 2016年第2期22卷 192-198页

作者：祝晓斌 Wang Qian Li Haisheng Guo xiaoxia xi yan Shen yang School of Computer and Information Engineering Beijing Technology and Business University Academy of Broadcasting Science SAPPRFT

Video synopsis is an effective and innovative way to produce short video abstraction for huge video archives,while keeping the dynamic characteristic of activities in the original *** activity,as the critical event,is always the main concern in video surveillance ***,in traditional video synopsis,all the normal and abnormal activities are condensed together equally,which can make the synopsis video confused and *** addition,the traditional video synopsis methods always neglect redundancy in the content *** solve the above-mentioned issues,a novel video synopsis method is proposed based on abnormal activity detection and key observation *** the proposed algorithm,activities are classified into normal and abnormal ones based on the sparse reconstruction cost from an atomically learned activity *** key observation selection using the minimum description length principle is conducted for eliminating content redundancy in normal *** conducted in publicly available datasets demonstrate that the proposed approach can effectively generate satisfying synopsis videos.

关键词： abnormal activity detection key observation selection sparse coding minimumdescription length (MDL) video synopsis

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Spontaneous dislocation of a toric implantable collamer lens resulting in corneal endothelial decompensation:a case report and review of the literature

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International Journal of Ophthalmology(English edition) 2023年第1期16卷 135-138页

作者： Li Zhang yan-xi Li Chun-yan Lei Lin Wang Mei-xia Zhang Sichuan University West China Hospital Chengdu 610041Sichuan ProvinceChina

Dear Editor We present a case of spontaneous dislocation of a toric implantable collamer lens(TICL)resulting in corneal endothelial decompensation 8y after *** 2006,by helping people take off their glasses,the Visian TICL(Staar Surgical Co,Monrovia,CA,USA)have gained popularity in *** complications of intraocular pressure(IOP)elevation,cataract formation and endothelial damage exist as relevant problems,implantable collamer lens(ICL)implantation has been generally accepted as a viable option to correct moderate to high ametropia[1-2].

关键词： dislocation implantation glasses

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Transformation of Upland Cotton (Gossypium hirsutum L.) with gfp Gene as a Visual Marker

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Journal of Integrative Agriculture 2012年第6期11卷 910-919页

作者： JIN Shang-xia LIU Guan-ze ZHU Hua-guo yanG xi-yan ZHANG xian-long National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070P.R.China

The green-fluorescent protein （gfp） gene was evaluated as a screening marker during cotton （Gossypium hirsutum L.） transforming and plant regeneration. High expression of GFP （green-fluorescent protein） was observed in transgenic cells as early as 42 h after co-culture with Agrobacterium. Most of the stable transformation events were detected in the cells of primary vascular tissue. GFP transient expression could be detected on all the explants after co-culturing for 4 d, however, the highest GFP stable expression was recorded when the explants were co-cultured for 3 d. We believe the transient and stable expression of a foreign gene in genetic transformation were two relative but different events, because high transient expression did not surely lead to high stable transformation. Under the same conditions of in vitro culture, transgenic and non-transgenic calli exhibited different morphological characters on different stages of development. High concentration of plant growth regulators （PGRs） was efficient for somatic embryogenesis of the transgenic calli, which means that the transgenic calli need relatively higher dose of hormone for further growth and somatic embryogenesis than non-transgenic ones. Strong GFP-expression was observed in leaf, stem, petioles, floral tissues, and seedlings of T~ progeny. Segregation ratios of eight transgenic lines were scored for expression of GFP in the T~ progeny that providing further evidence of stable transformation. These results proved that GFP is a powerful reporter gene for protocol optimization, selection, and monitioring in whole transformation events.

关键词： Agrobacterium cotton green-fluorescent protein (gfp) gene transformation plant regeneration

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