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Weakly Supervised Object Locali.ation with Background Suppression Erasing for Art Authentication and Copyright Protection

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Machine Intelli.ence Research 2024年第1期21卷 89-103页

作者： Chaojie Wu Mingyang li.Ying Gao Xinyan Xie Wing W.Y.ng Ahmad Musyafa School of Computer Science and Engineering South China University of TechnologyGuangzhou 511442China Guangdong Provincial Key Laboratory of Artificial Intelli.ence in Medical Image Analysis and Appli.ation Guangdong Provincial People's HospitalGuangzhou 510180China

The problem of art forgery and infringement is becoming increasingly prominent,since diverse self-media contents with all kinds of art pieces are released on the Internet every *** art paintings,object detection and locali.ation provide an efficient and ef-fective means of art authentication and copyright ***,the acquisition of a precise detector requires large amounts of ex-pensive pixel-level *** alleviate this,we propose a novel weakly supervised object locali.ation(WSOL)with background su-perposition erasing(BSE),which recognizes objects with inexpensive image-level ***,integrated adversarial erasing(IAE)for vanilla convolutional neural network(CNN)dropouts the most discriminative region by leveraging high-level semantic ***,a background suppression module(BSM)li.its the activation area of the IAE to the object region through a self-guidance ***,in the inference phase,we utili.e the refined importance map(RIM)of middle features to obtain class-agnostic loc-ali.ation *** experiments are conducted on paintings,CUB-200-2011 and ILSVRC to vali.ate the effectiveness of our BSE.

关键词： Weakly supervised object locali.ation erasing method deep learning computer vision art authentication and copyright protection

Electrolyte Effect on Photoetching of Galli.m Nitride

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Nanomanufacturing and Metrology 2024年第1期7卷 61-74页

作者： Huiqiang li.ng Zhenghao Wei Jiongchong Fang Yanming li.Changli.li.Zhirun Xie Yun Hau ng Guosong Zeng Shenzhen Key Laboratory of Intelli.ent Robotics and Flexible Manufacturing Systems Southern University of Science and TechnologyShenzhen 518055People’s Republic of China Department of Mechanical and Energy Engineering Southern University of Science and TechnologyShenzhen 518055People’s Republic of China School of Materials Sun Yat-Sen UniversityGuangzhou 510275People’s Republic of China School of Energy and Environment City University of Hong KongKowloon 999077Hong Kong SARPeople’s Republic of China City University of Hong Kong Shenzhen Research Institute Shenzhen Hi-Tech Industrial ParkNanshan DistrictShenzhen 518000People’s Republic of China SUSTech Energy Institute for Carbon Neutrali.y Southern University of Science and TechnologyShenzhen 518055People’s Republic of China

The li.ited material removal rate of conventional chemical mechanical poli.hing(CMP)significantly hinders the fabrica-tion efficiency and surface quali.y,thereby preventing the development of galli.m nitride(GaN)-based ***,the incorporation of photoelectrochemistry in CMP has garnered increasing attention because of its potential to enhance the quali.y and efficiency of the GaN ***,a considerable gap still exists in the comprehensive understanding of the specific photoelectrochemical(PEC)behavior of ***,we report the influence of the electrolyte on the PEC etching of *** acids and bases were tested,with their pH being carefully *** concentrations of the cations and anions were also *** results showed that photocorrosion/photoetching was more pronounced in sulfuric acid,phosphoric acid,and nitric acid environments than in alkali.e environments,but it was less pronounced in hydrochloric ***,the effects of pH and anion concentration on photoetching were investigated,and the results revealed that pho-toetching in acidic environments weakened with increasing pH levels and diminished with increasing sulfate *** underlying reasons contributing to this observation were *** findings provide ideas for improving the pho-toetching efficiency of GaN,thereby enriching the photoelectrochemical mechanical poli.hing(PECMP)technology of GaN.

关键词： GaN Photoelectrochemistry Photoetching pH

Emerging mechanisms of ferroptosis and its impli.ations in lung cancer

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Chinese Medical Journal 2024年第7期137卷 818-829页

作者： Qian li.Qibin Song Huadong Pei yali Chen Cancer Center Renmin Hospital of Wuhan UniversityWuhanHubei 430060China Department of Oncology Georgetown Lombardi Comprehensive Cancer CenterGeorgetown University Medical CenterWashington D.C.20057USA State Key Laboratory of Medical Proteomics National Center for Protein Sciences(Beijing)Beijing Institute of LifeomicsBeijing 102206China

Lung cancer is one of the most common mali.nancies and has the highest number of deaths among all *** continuous advances in medical strategies,the overall survival of lung cancer patients is still low,probably due to disease progression or drug *** is an iron-dependent form of regulated cell death triggered by the lethal accumulation of li.id peroxides,and its dysregulation is impli.ated in cancer *** evidence has shown that targeting the ferroptosis pathway could be a potential strategy for improving lung cancer treatment *** this review,we summarize the underlying mechanisms and regulatory networks of ferroptosis in lung cancer and highli.ht ferroptosis-targeting precli.ical attempts to provide new insights for lung cancer treatment.

关键词： Lung cancer Ferroptosis Ferroptosis regulators Ferroptosis inducers Cancer treatment

Modified Xiaoyao powder for postpartum depression:A systematic review and meta-analysis

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Journal of Traditional Chinese Medical Sciences 2024年第1期11卷 120-130页

作者： Mengyuan Hu Xiaowen Zhang Xuya Zhang Dan Cheng yali Zhang Xinyu Zhang li.gli.g li.Xinjie li.Xue li.Yi Lu School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing 102488China Centre for Evidence Based Chinese Medicine Beijing University of Chinese MedicineBeijing 100029China School of Chinese Medicine The University of Hong KongHong KongChina

Objective:To evaluate the effectiveness and safety of modified Xiaoyao powder for postpartum depression(PPD)by conducting a systematic review of randomized controlled trials(RCTs).Methods:The Chinese National Knowledge Infrastructure Databases(CNKI),the Chinese Scientific Journals Database(VIP),Wanfang,Google Scholar,the SinoMed,Embase,Cochrane li.rary,and PubMed databases were searched from their inception to April 25,*** Cochrane Risk of Bias tool was used to assess the quali.y of the *** appli.d the risk ratio to present dichotomous data and the mean difference to present continuous *** with similar characteristics were pooled for meta-analysis and heterogeneity was assessed using ***:This review included 35 trials involving 2848 *** quali.y of the included studies was low(unclear randomization processes and insufficient reporting of bli.ding).Participants treated with modified Xiaoyao powder plus Western medicine showed lower Hamilton Depression Scale(HAMD)depression score than those who used Western medicine alone(mean difference=-2.15;95%confidence interval:-2.52 to 1.78;Png modified Xiaoyao alone with Western medicine,the HAMD depression score remained low,however,the efficacy rate was higher in the modified Xiaoyao *** adverse events,the modified Xiaoyao group reported weight gain,nausea,and diarrhea,but no severe adverse events were ***:Modified Xiaoyao may help reli.ve depression in PPD when used alone or in combination with Western medicine,with minor side ***,future high-quali.y,large-sample size RCTs are warranted.

关键词： Postpartum depression Modified Xiaoyao Chinese medicine Systematic review Meta-analysis

PABP-driven secondary condensed phase within RSV inclusion bodies activates viral mRNAs for ribosomal recruitment

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Virologica Sinica 2024年第2期39卷 235-250页

作者： Qiang Zhang Hanzhe Ye Cong li. Haiwu Zhou Mingbin He Xiaodong li.ng Yu Zhou Kun Wang yali Qin Zhifei li.Mingzhou Chen State Key Laboratory of Virology and Modern Virology Research Center College of Life SciencesWuhan UniversityWuhan430072China Taikang Center for li.e and Medical Sciences Wuhan UniversityWuhan430072China Hubei Jiangxia Laboratory Wuhan430200China

Inclusion bodies(IBs)of respiratory syncytial virus(RSV)are formed by li.uid-li.uid phase separation(LLPS)and contain internal structures termed“IB-associated granules”(IBAGs),where anti-termination factor M2-1 and viral mRNAs are ***,the mechanism of IBAG formation and the physiological function of IBAGs are ***,we found that the internal structures of RSV IBs are actual M2-1-free viral messenger ribonucleoprotein(mRNP)condensates formed by secondary ***,the RSV nucleoprotein(N)and M2-1 interact with and recruit PABP to IBs,promoting PABP to bind viral mRNAs transcribed in IBs by RNArecognition motif and drive secondary phase ***,PABP-eIF4G1 interaction regulates viral mRNP condensate composition,thereby recruiting specific translation initiation factors(eIF4G1,eIF4E,eIF4A,eIF4B and eIF4H)into the secondary condensed phase to activate viral mRNAs for ribosomal *** study proposes a novel LLPS-regulated translation mechanism during viral infection and a novel antiviral strategy via targeting on secondary condensed phase.

关键词： Respiratory syncytial virus(RSV) Inclusion bodies(IBs) Biomolecular condensates li.uid-li.uid phase separation(LLPS) Secondary condensed phase mRNA activation

Effect of autologous bone marrow stem cells-scaffold transplantation on the ongoing pregnancy rate in intrauterine adhesion women:a randomized,controlled trial

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Science China(li.e Sciences) 2024年第1期67卷 113-121页

作者： Hui Zhu Taishun li.Peizhen Xu li.un Ding Xianghong Zhu Bin Wang Xiaoqiu Tang Juan li.Pengfeng Zhu Huiyan Wang Chenyan Dai Haixiang Sun Jianwu Dai yali Hu Department of Obstetrics and Gynecology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing 210008China Department of Biostatistics Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing 210008China Department of Gynecology Changzhou Maternal and Child Health Care HospitalChangzhou Medical CenterNanjing Medical UniversityChangzhou 213004China Cli.ical Center for Stem Cell Research Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing 210008China Department of Hematology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing 210008China Institute of Genetics and Developmental Biology Chinese Academy of SciencesBeijing 100190China

Intrauterine adhesion is a major cause of female reproductive *** we and others uncontrolled pilot studies showed that treatment with autologous bone marrow stem cells made a few patients with severe intrauterine adhesion obtain li.e birth,no large sample randomized controlled studies on this therapeutic strategy in such patients have been reported so *** verify if the therapy of autologous bone marrow stem cells-scaffold is superior to traditional treatment in moderate to severe intrauterine adhesion patients in increasing their ongoing pregnancy rate,we conducted this randomized controlled cli.ical *** 195 participants with moderate to severe intrauterine adhesion were screened and 152 of them were randomly assigned in a 1:1 ratio to either group with autologous bone marrow stem cells-scaffold plus Foley balloon catheter or group with only Foley balloon catheter(control group)from February 2016 to January *** per-protocol analysis included 140 participants:72 in bone marrow stem cells-scaffold group and 68 in control *** ongoing pregnancy occurred in 45/72(62.5%)participants in the bone marrow stem cells-scaffold group which was significantly higher than that in the control group(28/68,41.2%)(RR=1.52,95%CI 1.08–2.12,P=0.012).The situation was similar in li.e birth rate(bone marrow stem cells-scaffold group 56.9%(41/72)*** group 38.2%(26/68),RR=1.49,95%CI 1.04–2.14,P=0.027).Compared with control group,participants in bone marrow stem cells-scaffold group showed more menstrual blood volume in the 3rd and 6th cycles and maximal endometrial thickness in the 6th cycle after hysteroscopic *** incidence of mild placenta accrete was increased in bone marrow stem cells-scaffold group and no severe adverse effects were *** conclusion,transplantation of bone marrow stem cells-scaffold into uterine cavities of the participants with moderate to severe intrauterine adhesion increased their ongoing pregnancy and

关键词： intrauterine adhesion Asherman’s syndrome uterine infertili.y autologous bone marrow stem cells transplantation endometrial regeneration ongoing pregnancy rate

Simultaneous microwave characterization of wafer-level optoelectronic transceiver chips based on photonic sampli.g and mapping

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Science China(Information Sciences) 2024年第2期67卷 337-338页

作者： Yutong HE Xinhai ZOU Ying XU Zhihui li.Naidi CUI Junbo FEng yali ZHAng Zhiyao ZHAng Shangjian ZHAng Yong li. Ninghua ZHU Research Center for Microwave Photonics State Key Laboratory of Electronic Thin Films and Integrated DevicesSchool of Optoelectronic Science and EngineeringUniversity of Electronic Science and Technology of China Chongqing United Microelectronics Center (CUMEC) Xiongan Institute of Innovation Chinese Academy of Sciences

Photonic integrated circuits(PICs) promise future paralleli.m growths of high-performance communication, computation, and offer unprecedented bandwidth scalabili.y with reduced power consumption as a viable replacement for an electrical wire with an optoelectronic transceiver consisting of a transmitter and a receiver integrated on the same wafer.

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Structural insight into palladium-nickel clusters over mordenite zeoli.e for carbene-insertion reaction

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Frontiers of Chemical Science and Engineering 2024年第9期18卷 89-99页

作者： Guangchao li.Ping-Luen Baron Ho Bryan Kit Yue ng Tai-Sing Wu Pawel Rymarz Shik Chi Edman Tsang Department of Appli.d Biology and Chemical Technology The Hong Kong Polytechnic UniversityHong Kong 999077China Department of Chemistry University of OxfordOxford OX13QRUK Synchrotron Radiation Research Center Hsinchu 30076China

The advancement of heterogeneous catalysts incorporating metal clusters in the nanometric size range has garnered significant attention due to their extraordinary catalytic activity and *** detailed characterization and understanding of the atomic structure of these metal clusters within catalysts is crucial for elucidating the underlying reaction *** the present study,a distinctive three-atom PdNi cluster,characterized by two Pd atoms at terminal positions and a central Ni atom,was synthesized over mordenite *** presence of atomic PdNi clusters within the eight-membered ring side pocket area was confirmed by multiple advanced analytical techniques,including magic-angle spinning nuclear magnetic resonance spectroscopy,synchrotron X-ray powder diffraction,extended X-ray absorption fine structure spectroscopy,and high-angle annular dark-field scanning transmission electron *** catalytic activity of the confined active species was examined by the carbene-mediated reactions of ethyl-2-diazoacetate to ethyl-2-methoxyacetate as a model *** to the Pd-mordenite and Ni-mordenite,the PdNi-mordenite catalyst incorporates a PdNi cluster,which demonstrates a superior performance,achieving 100%conversion and high selectivity under the same reaction *** study elucidates the potential of constructing bimetalli. clusters in zeoli.es,providing valuable insights for developing new heterogeneous catalysts appli.able to a wide range of catalytic processes.

关键词： zeoli.e metal cluster synchrotron X-ray diffraction carbene-mediated reaction

Topology modulation of tetraphenylethylene graphdiyne at a li.uid-li.uid interface

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Nano Research 2024年第6期17卷 4661-4667页

作者： Tingting Xu Pei Wen ng Shaofei Wu Danjun Fu Yunhan Ma Yao li. li.ao li.Xiaofei Zhang Jun Zhu Department of Chemistry National University of SingaporeSingapore 117543Singapore Institute of Materials Research and Engineering(IMRE) Agency for ScienceTechnology and Research(A*STAR)Singapore 138634Singapore

Monomers with low symmetries can form different topological structures in the preparation of organic two-dimensional(2D)***,it remains challenging to modulate the topologies in practical *** theoretical insights into the formation energy of potential structural configurations,we report the topology modulation of a graphdiyne(GDY)derivative constructed from two-fold symmetric tetrakis(4-ethynylphenyl)ethene precursor by changing solvent combinations in a li.uid-li.uid interfacial *** aqueous-organic(water-dichloromethane)interface afforded GDY with a kagome topology while a rhombic topology was formed at an organic-organic(hexane-acetonitrile)interface.A comprehensive evaluation of their structures and optoelectronic properties was conducted through various characterization techniques and theoretical *** study provided new insights to modulate the topology of not only GDY but also other framework structures and obtain topologically pure materials in situations where different topologies are possible during practical synthesis.

关键词： graphdiyne derivative tetraphenylethylene topology modulation aggregation-induced emission(AIE)two-dimensional(2D)polymers interfacial synthesis