检索结果-南通市图书馆

The Influence of Different Surgical Schemes on the Healing and Cosmetic Effects of Skin Lesions

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Biomedical Engineering(English Edition) 2020年第4期29卷 30-35页

作者： Jiang Qian Cuirong Shen Caili Xie Haili Wu Yalan Tian Xiaolan Hong Department of Dermatology 909 Hospital of Chinese People's Liberation Army/The Affiliated Dongnan Hospital of Xiamen UniversityZhangzhou Fujian 36300China Outpatient Department Gulangyu Sanatorium of PLAXiamen Fujian 361000China

Objective To analyze the effects of different surgical procedures on the healing and cosmetic effects of skin lesions.Methods 102 patients with skin defects after skin tumor resection in our hospital from January 2018 to December 2019 were selected and randomly divided into observation group and control group.The control group was treated with a traditional skin flap transplantation,while the observation group was treated with a skin stretch closure device.The effective rate,bleeding volume,wound healing time,total scar length,short-term and long-term complications and patient satisfaction were compared between the two groups.Results The effective rates of the observation group and the control group were 90.2%and88.24%,there was no significant difference in the treatment efficiency between the two groups(P>0.05),but there were significant differences in the amount of bleeding,the time of wound healing and the total length of postoperative scars between the two groups(all P<0.05);the short-term complication rates of the observation group and the control group were 5.88%and 19.61%,and long-term complications rate was 1.96%and 13.73%.The difference in the incidence of short-term and long-term complications between the two groups was statistically significant(all P<0.05);the satisfaction rate of patients in the observation group and the control group was 90.2%and 72.55%,the difference was statistically significant(P<0.05).Conclusion The former can effectively shorten wound healing time and scar length,reduce the incidence of short-term and long-term complications,and improve patients’satisfaction with the treatment,which is worthy of promotion.

关键词： skin tumor skin repair and healing cosmetic effect skin tension closure device

新技术媒介中传统神话的解构与重构:动画电影《白蛇2:青蛇劫起》

在线全文

学校读者我要写书评

暂无评论

电影评介 2022年第18期 109-112页

作者：司桂松田雅岚重庆文理学院美术与设计学院

一、民间传说的故事变迁与文本解构《白蛇2:青蛇劫起》的题材源于中国民间广为流传的白蛇故事,但并没有重述白蛇与许仙的爱情悲剧,而是讲述由白蛇被镇在雷峰塔下发生的一个与白蛇故事截然不同的复仇故事。与前作《白蛇:缘起》一样,传统... 详细信息

一、民间传说的故事变迁与文本解构《白蛇2:青蛇劫起》的题材源于中国民间广为流传的白蛇故事,但并没有重述白蛇与许仙的爱情悲剧,而是讲述由白蛇被镇在雷峰塔下发生的一个与白蛇故事截然不同的复仇故事。与前作《白蛇:缘起》一样,传统白蛇故事中最重要的许仙与法海形象在《白蛇2:青蛇劫起》中基本是缺席的:《白蛇:缘起》中为爱牺牲生命的捕蛇者阿宣不畏困难追求真情,与白蛇传说中软弱妥协的许仙截然不同;而青蛇和白蛇的形象也进行了较大改动,与全国各地流传的民间传说均有较大出入。

关键词：白蛇故事爱情悲剧许仙民间传说复仇故事雷峰塔解构与重构文本解构

Protective effect of N-acetylcysteine against lipopolysaccharide injury in hepatocytes of neonatal mice

在线全文

学校读者我要写书评

暂无评论

Frontiers of Medicine 2008年第2期2卷 182-185页

作者： Lin WANG Jianbo XU Yuan tian Heshui WU yalan LIU Department of Pediatrics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of General Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

The present study provides supportive evid-ence for the effective prevention and treatment of lipopo-lysaccharide(LPS)-induced hepatocyte injury in neonatal mice by N-acetylcysteine(NAC).Hepatocytes of neonatal mice were obtained through collagenase digestion of the liver.The hepatocytes were treated either with LPS(10 mg/mL)alone or with NAC(5 mmol/L)for 1 h before the addition of LPS(10 mg/mL).After LPS treatment,12 wells of the cultured hepatocytes and supernatants were harvested at 0,6,and 12 h,respectively.Levels of alanine aminotransferase(ALT)and nitric oxide(NO)in the supernatant were biochemically quantified and reverse transcription-polymerase chain reaction(RT-PCR)was performed to detect the expression of inducible nitric oxide synthase(iNOS)mRNA after different treatments.At 0 h following the treatment of primary cultured hepa-tocytes with LPS,the levels of ALT,NO and iNOS mRNA in the supernatant were(21.1±4.78)u/L,(1.6±0.31)mmol/L and 0.17±0.023,respectively;at 6 h,(59.8±8.59)u/L,(6.6±0.81)mmol/L,and 0.71±0.091;and at 12 h,(89.6±15.30)u/L,(7.8±1.01)mmol/L,and 0.71±0.097.The levels of ALT,NO and iNOS mRNA at 6 and 12 h increased significantly,compared to those at 0 h(P<0.01).In contrast to LPS treatment alone,pre-treatment with NAC before LPS addition significantly reduced the levels of ALT,NO and iNOS mRNA in the supernatant at 6 h to(40.8±7.30)u/L,(3.2±0.71)mmol/L,and 0.41±0.060;and at 12 h to(55.4±5.48)u/L,(4.0±0.71)mmol/L,and 0.40¡0.067,respectively(P<0.01).However,the levels of ALT,NO and iNOS mRNA at 0 h did not change significantly with both treat-ment approaches.NAC has protective effects in hepato-cytes of neonatal mice against LPS-induced injury as shown by the reduced levels of ALT,NO and iNOS mRNA when primary hepatocytes were treated with NAC prior to LPS stimulation.We postulate that NAC exhibits its protective function by inhibiting LPS-induced transcription of iNOS,resulting in decreased levels of NO.

关键词： N-acetylcysteine endotoxin hepatocytes nitric oxide inducible nitric oxide synthase

PPARδ regulates dendritic cell function in atherosclerosis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

PPARδ regulates dendritic cell function in atherosclerosis

Beneficial Effects of Celastrol on Immune Balance by Modulating Gut Microbiota in Experimental Ulcerative Colitis Mice

第十一届海峡两岸心血管科学研讨会、2017年全国心脑血管药理学术会议、中国卒中学会第一次新药研讨会

作者： Wu yalan tian Danyang Huang Yuhong Ma Qingyun Huang Yu tian Xiaoyu The Chinese University of Hong Kong

Rationale and Hypothesis:Atherosclerosis is a chronic sterile inflammation of the vascular wall triggered by hyperlipidemia.Macrophage is the major player which can be transformed into foam cells,gradually forming a necrotic core,with the migrated vascular smooth muscle cells and fibroblast forming a fibrous cap.However,the role of dendritic cells(DCs) in the development of atherosclerosis has not been recognized until the last decade.DCs contribute to early foam cell formation,regulate

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Genomics, Proteomics & Bioinformatics 2022年第2期20卷 288-303页

作者： Mingyue Li Weina Guo yalan Dong Wenzhu Wang Chunxia tian Zili Zhang Ting Yu Haifeng Zhou Yang Gui Kaming Xue Junyi Li Feng Jiang Alexey Sarapultsev Huafang Wang Ge Zhang Shanshan Luo Heng Fan Desheng Hu Department of Integrated Traditional Chinese and Western Medicine Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Gastroenterology Zhongda HospitalSoutheast UniversityNanjing 210009China Institute of International Education Tianjin University of Traditional Chinese MedicineTianjin 301617China Institute of Immunology and Physiology Ural Branch of the Russian Academy of SciencesEkaterinburg 620049Russia Institute of Hematology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Institute of Integrated Bioinfomedicine and Translational Science School of Chinese MedicineHong Kong Baptist UniversityHong Kong Special Administrative Region 999077China

Ulcerative colitis(UC)is a chronic inflammatory bowel disease caused by many factors including colonic inflammation and microbiota dysbiosis.Previous studies have indicated that celastrol(CSR)has strong anti-inflammatory and immune-inhibitory effects.Here,we investigated the effects of CSR on colonic inflammation and mucosal immunity in an experimental colitis model,and addressed the mechanism by which CSR exerts the protective effects.We characterized the therapeutic effects and the potential mechanism of CSR on treating UC using histological staining,intestinal permeability assay,cytokine assay,flow cytometry,fecal microbiota transplantation(FMT),16S rRNA sequencing,untargeted metabolomics,and cell differentiation.CSR administration significantly ameliorated the dextran sodium sulfate(DSS)-induced colitis in mice,which was evidenced by the recovered body weight and colon length as well as the decreased disease activity index(DAI)score and intestinal permeability.Meanwhile,CSR down-regulated the production of pro-inflammatory cytokines and up-regulated the amount of anti-inflammatory mediators at both mRNA and protein levels,and improved the balances of Treg/Th1 and Treg/Th17 to maintain the colonic immune homeostasis.Notably,all the therapeutic effects were exerted in a gut microbiota-dependent manner.Furthermore,CSR treatment increased the gut microbiota diversity and changed the compositions of the gut microbiota and metabolites,which is probably associated with the gut microbiota-mediated protective effects.In conclusion,this study provides the strong evidence that CSR may be a promising therapeutic drug for UC.

关键词： Ulcerative colitis Celastrol Gut microbiota Treg/Th balance Metabolomics

在线全文

学校读者我要写书评

暂无评论

奚嘉教授治疗肥胖型多囊卵巢综合征经验总结

山西中医药大学学报 2023年第8期24卷 885-888,892页

作者：田亚兰李婷秦文敏南京中医药大学江苏南京210023 南京中医药大学徐州附属医院江苏徐州221010

多囊卵巢综合征(PCOS)是妇科临床常见疾病,近年来其发病率较高,严重困扰着育龄期女性。奚嘉教授为江苏省名中医,根据其40多年的临床经验,认为肥胖型PCOS为本虚标实之证,肾虚为本,痰湿为标,在治疗的第一阶段以化痰散结为主,同时加入补肾... 详细信息

多囊卵巢综合征(PCOS)是妇科临床常见疾病,近年来其发病率较高,严重困扰着育龄期女性。奚嘉教授为江苏省名中医,根据其40多年的临床经验,认为肥胖型PCOS为本虚标实之证,肾虚为本,痰湿为标,在治疗的第一阶段以化痰散结为主,同时加入补肾助阳药物,理气、助阳并重,使肾阳充足,水液代谢正常,减轻体内痰湿,减轻胞宫脂膜。在治疗的第二阶段以补肾调经为主,肾主生殖发育,肾气充足,气血充盛,阴阳平衡,肾-天癸-冲任-胞宫生殖轴运转协调,则月经调和,可正常受孕。奚嘉教授认为PCOS以肾虚为本,但非一脏所致;以痰浊为标,但痰浊并非单一病理产物。其病位在肾、肝、脾,治疗时根据具体症状适当加入理气行气、活血化瘀药调畅气机,使脉道通畅,为卵泡的排出提供良好的环境。

关键词：多囊卵巢综合征肥胖型奚嘉名医经验

The association between breastfeeding and early childhood caries in children:an update meta-analysis

在线全文

学校读者我要写书评

暂无评论

The association between breastfeeding and early childhood ca...

ALA和氨基酸肥料对桃光合特性及品质的影响

达能营养中心第十八届学术年会

作者：崔玲玲 Yalan Tian Ling Wang Dongmei Xu Bing Zhao Yan Wang Linyuan Zhao Xiaohuan Zhang WenJie Li 郑州大学公共卫生学院营养与食品卫生教研室 Department of Nutrition and Food Hygiene College of Public HealthZhengzhou University Department of Health the Third Affiliated HospitalZhengzhou University

Background:Epidemiologic studies have yielded inconsistent findings between breastfeeding and risk of early childhood caries(ECC).Objective:We performed a meta-analysis to summarize available evidence from cohort,case-control,and crosssectional studies of the association between feeding pattern and breastfeeding duration and ECC risk from published observational studies.Design:Studies were identified by searching PubMed,Embase,ISI Web of Science,and the Cochrane Library from 1990 to 2015 August and by reviewing the reference lists of pertinent articles.Random-effects models were used to estimate pooled odds ratios(ORs) using ST ATA 12.0.Results:34 studies(9 birth cohorts studies,4 case-control studies and 21 cross-sectional studies) consisting of64315 children were included.Pooled results from 21 studies found no significant association for ever breastfeeding and ECC compared with never breastfeeding(OR:0.80;95%CI:0.62-1.02,P=0.069) with high evidence of heterogeneity(I= 85.8%,P< 0.001).However,subgroup analysis only found ever breastfeeding could decrease the risk of ECC in the studies of 3-6 years old children(OR = 0.74,95%CI:0.57-0.98,P = 0.034),NOS ≥6(OR=0.66,95%CI:0.44-0.99,P=0.043),sample size more than 500 subjects(OR = 0.67,95%CI:0.47-0.94,P =0.021),published after 2010(OR = 0.47,95%CI:0.25-0.86,P = 0.015).Pooled analysis from 15 studies shown that breastfeeding longer than 12 months could increase the risk of ECC compared with breastfeeding shorter than12 months(OR=1.91,95%CI:1.41-2.59,P< 0.001) with high evidence of heterogeneity(I=89.9%,P< 0.001).Conclusions:Results of this meta-analysis suggest that ever breastfeeding may protect against ECC,and breastfeeding duration longer than 12 months is associated with higher risks of ECC.Additional research is needed to estimate the effect after adjusting for other possible confounding factors.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

分子植物育种 2022年第6期20卷 1930-1936页

作者：杨雅兰王诗赞田旖王聪敏商丘学院风景园林学院商丘476000 湖南省湘北职业中专学校常德415000

以桃(Prunu persica L.Batsch)为研究材料,在其生长发育期间喷施稀释75倍、150倍5-氨基乙酰丙酸(ALA)稀释液以及1 000、2 000倍‘禾稼春’氨基酸水溶性肥稀释液,检测桃树叶片SPAD、叶绿素快速荧光特性、单果重、以及果实品质。结果显示... 详细信息

以桃(Prunu persica L.Batsch)为研究材料,在其生长发育期间喷施稀释75倍、150倍5-氨基乙酰丙酸(ALA)稀释液以及1 000、2 000倍‘禾稼春’氨基酸水溶性肥稀释液,检测桃树叶片SPAD、叶绿素快速荧光特性、单果重、以及果实品质。结果显示:不同稀释倍数的ALA溶液和‘禾稼春’,均能不同程度地提高桃树叶片SPAD值、诱导I-P相荧光强度增加,叶片单位面积PSⅡ反应中心吸收(ABS/CSm)、捕获(TR_(0)/CSm)的能量上升,而热耗散量(DI_(0)/CSm)显著下降,J相相对荧光(V_(J))和PSⅡ反应中心最大关闭速率(Mo)下降,桃树叶片的光合性能指数(PI_(ABS),PI_(CS),PI_(total))显著上升。此外,ALA及‘禾稼春’处理后能显著提高桃单果重,同时果实可溶性固形物、可溶性蛋白、可溶性糖、VC及花青素含量得到不同程度提高,但降低可滴定酸含量。可见,ALA溶液和‘禾稼春’可应用于桃生产,增强桃光合作用,提高桃果实品质。

关键词： ALA ‘禾稼春’ 桃光合作用品质

在线全文

学校读者我要写书评

暂无评论

快速康复外科在麻醉中应用的研究进展

临床医学工程 2017年第3期24卷 434-436页

作者：田和李雅兰暨南大学附属第一医院麻醉科广东广州510632

快速康复外科(ERAS)被大量临床循证医学研究所证实,通过减少患者的应激反应和并发症,达到改善患者预后和减少住院时间的目的。ERAS理念贯穿整个麻醉工作中,优化与完善围术期的麻醉管理。本文对ERAS在麻醉中的研究和应用概况作一综述。

关键词：快速康复外科麻醉进展