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Mononeuropathy multiplex associated with systemic vasculitis:A case report

World Journal of Clinical Cases 2021年第7期9卷 1741-1747页

作者： Hyun Jun Chae Jung Woo Kim yae lim lee Jeong Hwan Park Sang Yoon lee Department of Rehabilitation Medicine Seoul National University College of MedicineSeoul National University HospitalSeoul 07061South Korea Department of Pathology Seoul National University College of MedicineSMG-SNU Boramae Medical CenterSeoul 07061South Korea Department of Rehabilitation Medicine Seoul National University College of MedicineSMG-SNU Boramae Medical CenterSeoul 07061South Korea

BACKGROUND Vasculitis,a systemic disorder with inflammation of blood vessel walls,can develop broad spectrum of signs and symptoms according to involvement of various organs,and therefore,early diagnosis of vasculitis is *** herein describe a patient who developed a special case of systemic vasculitis with mononeuropathy multiplex,rectal perforation and antiphospholipid syndrome(APS)presented with pulmonary *** SUMMARY A 61-year-old woman visited hospital with complaints of myalgia and occasional *** was initially diagnosed as proctitis and treated with antibiotics,however,there was no *** addition,she also complained right foot drop with hypesthesia,and left 2^(nd) and 3^(rd) finger tingling *** underwent nerve conduction study for evaluation,and it revealed sensorimotor polyneuropathy in the left arm and bilateral *** sural nerve biopsy strongly suggested vasculitic *** on nerve biopsy and clinical manifestation,she was diagnosed with vasculitis and treated with immunosuppressive *** treatment,sudden rectal perforation and pulmonary thromboembolism occurred,and further laboratory study suggested probable concomitant *** Hartmann operation was performed for rectal perforation,and anti-coagulation therapy was started for *** few cycles of immunosuppressive therapy,tingling sensation and weakness in her hand and foot had been partially recovered and vasculitis was considered to be *** Vasculitis can be presented with a variety of signs and symptoms,therefore,clinicians should always consider the possibility of diagnosis.

关键词： Systemic Vasculitis Peripheral nervous system diseases Mononeuropathies Antiphospholipid syndrome Pulmonary embolism Case report

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Single-cell and spatial omics:exploring hypothalamic heterogeneity

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Neural Regeneration Research 2025年第6期20卷 1525-1540页

作者： Muhammad Junaid Eun Jeong lee Su Bin lim Department of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Graduate School of Ajou UniversitySuwonSouth Korea Department of Brain Science Ajou University School of MedicineSuwonSouth Korea

Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technologies have significantly evolved, overcoming initial technical challenges in capturing and analyzing individual cells. These high-throughput omics technologies now offer a remarkable opportunity to comprehend the complex spatiotemporal patterns of transcriptional diversity and cell-type characteristics across the entire hypothalamus. Current single-cell and single-nucleus RNA sequencing methods comprehensively quantify gene expression by exploring distinct phenotypes across various subregions of the hypothalamus. However, single-cell/single-nucleus RNA sequencing requires isolating the cell/nuclei from the tissue, potentially resulting in the loss of spatial information concerning neuronal networks. Spatial transcriptomics methods, by bypassing the cell dissociation, can elucidate the intricate spatial organization of neural networks through their imaging and sequencing technologies. In this review, we highlight the applicative value of single-cell and spatial transcriptomics in exploring the complex molecular-genetic diversity of hypothalamic cell types, driven by recent high-throughput achievements.

关键词： cellular diversity hypothalamus multi-omics single-cell transcriptomics spatial transcriptomics

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Landau damping of twisted waves in Cairns distribution with anisotropic temperature

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Plasma Science and Technology 2021年第8期23卷 18-28页

作者： Sunggeun lee Hankwon lim School of Energy and Chemical Engineering UNIST50UNIST-gilEonyang-eupUlju-gunUlsan 44919Republic of Korea

The consideration of orbital angular momentum of an electric field(twisted mode)is applied to the kinetic theory of *** linearized Vlasov–Poisson equation is solved for the anisotropic thermal distributed bi-Maxwellian and Cairns distributions of electrons to obtain the damping rates of twisted *** dispersion relation and Landau damping of Langmuir twisted modes are *** presence of twisted modes opens up two more possibilities in Landau damping and dispersion *** may generate a mixture with ion sound *** seems to play the role of a control parameter of Landau damping.

关键词： Landau damping Cairns distribution function anisotropic

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Emissions of Er3+ and Yb3+ co-doped SrZrO3 nanocrystals under near-infrared and near-ultraviolet excitations

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Journal of Advanced Ceramics 2020年第4期9卷 413-423页

作者： Hyeontae lim Juyeong lim Soyoung Jang Y.S.lee Department of Physics Soongsil UniversitySeoul06978Republic of Korea

In this study,the upconversion(UC)emissions of Er3+and Yb3+co-doped SrZrO3 nanocrystals(NCs)were investigated in terms of the thermal annealing temperature and concentration of Er3+ions and compared with the emissions under a near-ultraviolet(near-UV)*** NCs were synthesized by the combustion method,and the as-synthesized NCs were post-annealed at high *** X-ray diffraction patterns revealed that the grain sizes and crystallinity degrees of the samples increased with increasing annealing *** photoluminescence spectra of our samples exhibited strong green and very weak red emissions with the near-UV excitation,originating from the f-f transitions in the Er3+***,under near-infrared(near-IR)excitation,we identified sizable visible emissions at 525,547,and 660 nm in our NCs,which indicated that the UC process successfully occurred in our *** UC emissions were maximized in the NCs with an Er3+concentration of 0.02 and thermal annealing at 1000°*** found that the intensity ratios of red to green emissions increased with increasing annealing *** discussed the differences in the emissions between near-UV and near-IR excitations.

关键词： Er3+and Yb3+co-doped SrZrO3 upconversion downshifting nanocrystals combustion method annealing temperature

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Nasal cavity fungus ball discovered accidentally:A case report

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World Journal of Clinical Cases 2025年第5期13卷 44-48页

作者： Dae-Neung lee Dong Hoon lee Sang Chul lim Department of Otolaryngology-Head and Neck Surgery Chonnam National University Medical SchoolChonnam National University Hwasun HospitalHwasun 58128South Korea Department of Otolaryngology-Head and Neck Surgery Chonnam National University Medical SchoolHwasun HospitalChonnam National University Hwasun HospitalHwasun 58128South Korea Department of Otolaryngology-Head and Neck Surgery Chonnam National University Medical SchoolKwangju 501190South Korea

BACKGROUND Fungal balls within the nasal cavity are an exceedingly rare clinical entity,typically presenting with nonspecific symptoms or being identified *** SUMMARY This report presents an incidental discovery of a fungal ball in the nasal cavity during routine imaging,with no associated clinical *** This case underscores the importance of considering the possibility of asympto-matic presentations of nasal fungal balls,which may be detected incidentally during imaging evaluations.

关键词： Fungi Mycoses Fungus ball Nasal cavity Nasal surgical procedures Case report

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Detection of chemicals in water using a three-dimensional graphene porous structure as liquid-vapor separation filter

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Nano Research 2017年第3期10卷 971-979页

作者： Taekyung lim Jaejun lee Jonghun lee Sanghyun Ju Department of Physics Kyonggi University Suwon Gyeonggi-Do 443-760 Republic of Korea

In this study, we report the utilization of a three-dimensional （3D） porous graphene structure as liquid-vapor separation filter, which allows the passage of chemical vapors while blocking liquid chemicals and water. The blockage of liquid chemicals and water from semiconducting sensing regions is required to avoid abnormal transistor characteristics. In order to impart omniphobic characteristics, a （heptadecafluoro-1,1,2,2-tetrahydrodecyl）trichlorosilane （HDF-S） self-assembled monolayer was coated on the surface of the 3D porous graphene structure. The concentration of chemical agents in water could be consistently detected by observing the shift in the threshold voltage in the oxide nanowire transistor covered by the HDF-S self-assembled 3D graphene structure. The proposed monitoring method is expected to offer means for application in different environments by providing a stable sensing performance.

关键词： chemical detection graphene structure nanowire transistor self-assembled monolayer omniphobicity

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Direct high-resolution X-ray imaging exploiting pseudorandomness

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Light(Science & Applications) 2023年第5期12卷 776-788页

作者： KyeoReh lee Jun lim Su Yong lee YongKeun Park Department of Physics Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea KAIST Institute for Health Science and Technology Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Pohang Accelerator Laboratory Pohang University of Science and TechnologyPohangKyungbuk 37637Republic of Korea Tomocube Inc Daejeon 34051Republic of Korea

Owing to its unique penetrating power and high-resolution capability,X-ray imaging has been an irreplaceable tool since its *** the significance,the resolution of X-ray imaging has largely been limited by the technical difficulties on X-ray lens *** lensless imaging methods have been proposed,but are yet relying on multiple measurements or additional constraints on measurements or *** we present coherent specklecorrelation imaging(CSI)using a designed X-ray *** has no prerequisites for samples or ***,from a single shot measurement,the complex sample field is retrieved based on the pseudorandomness of the speckle intensity pattern,ensured through a *** achieve a spatial resolution of 13.9 nm at 5.46 keV,beating the feature size of the diffuser used(300 nm).The high-resolution imaging capability is theoretically explained based on fundamental and practical *** expect the CSI to be a versatile tool for navigating the unexplored world of nanometer.

关键词： resolution speckle replace

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A silane-based host material with improved electron transport properties for phosphorescent OLEDs with high efficiency and low efficiency roll-off

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Science China Materials 2023年第5期66卷 1997-2003页

作者： Jinho Park Junseop lim Jun Yeob lee School of Chemical Engineering Sungkyunkwan University 2066Seobu-roJangan-guSuwon-siGyeonggi-do16419Republic of Korea

A dibenzosilole-based host material was designed and *** host material,9,9'-(5,5-diphenyl-5H-dibenzo[b,d]silole-2,8-diyl)bis(9H-carbazole)(SSiCz),was designed to enhance the electron transport properties and rigidity by coupling two phenyl units of the tetraphenyl silane of a strong hole transport type bis(4-(9Hcarbazol-9-yl)phenyl)diphenylsilane *** device efficiency roll-off was improved considerably by balancing the carriers in the phosphorescent organic light-emitting diodes(PhOLEDs),and the driving voltage at high luminance was *** red and green PhOLEDs exhibited high external quantum efficiencies(EQEs)of 23.8%and 24.9%,respectively,and a relieved efficiency *** addition,S-SiCz was used as an electron transport type host with a hole transport type3,3'-di(9H-carbazol-9-yl)-1,1'-biphenyl *** maximum EQEs of the red and green PhOLEDs using the mixed host were 26.0%and 25.5%,respectively,and EQE roll-off values were 18%and 6%,***,the planarization design strategy of the host is effective for better device performance.

关键词： OLEDs host material silane bipolar phosphorescent OLEDs

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A novel benzo[4,5]furo[3,2-d]pyrimidine-based host as a n-type host for blue phosphorescent organic light-emitting diodes

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Science China Materials 2022年第4期65卷 1028-1033页

作者： Junsu Ha Junseop lim Jun Yeob lee School of Chemical Engineering Sungkyunkwan University2066Seobu-roJangan-guSuwon-siGyeonggi-do16419Republic of Korea

An electron-transport-type host was synthesized using a benzo[4,5]furo[3,2-d]pyrimidine(BFP)core to develop a high triplet energy *** host was designed to have both the tetraphenylsilyl blocking group and the hole-transport-type carbazole *** the device application,the host was used as an electron-transport-type host mixed with a hole-transport-type 3,3'-di(9H-carbazol-9-yl)-1,1†-biphenyl(mCBP)host in the blue phosphorescent organic light-emitting diodes(PhO-LEDs)doped with a[[5-(1,1-dimethylethyl)-3-phenyl-1H-imidazo[4,5-b]pyrazin-1-yl-2(3H)-ylidene]-1,2-phenylene]bis-[[6-(1,1-dimethylethyl)-3-phenyl-1H-imidazo[4,5-b]pyrazin-1-yl-2(3H)-ylidene]-1,2-phenylene]iridium(Ir(cb)3)blue *** a result,the mCBP:CzBFPmSi mixed host showed high external quantum efficiency over 20%at 1000 cd m^(−2) and low efficiency roll-off in the blue PhOLEDs.

关键词： blue device host efficiency lifetime

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Feasibility Study of R134a/R404a Cascade Heat Pump Cycle in Heat Pump Dryers with Electrical Heaters at Low Temperatures

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Journal of Thermal Science 2015年第5期24卷 463-467页

作者： Ji Woo Jeong Young lim lee Dept. of Mechanical Engineering Kongju National University Dept. of Mechanical and Automotive Engineering Kongju National University

Heat pump cycles have been widely applied to dryers for their high efficiency. However, low–efficiency electrical heaters are often used during early drying stage for frozen foods or winter since a standard heat pump cycle cannot operate at low temperature. This study introduced cascade heat pumps replacing electrical heaters to improve dryer performance at low temperatures. Experiments were performed to examine changes in performance of the cascade heat pump dryers in relation to ambient temperature, low-stage cycle mass flow rate, and high-stage cycle mass flow rate. The results showed a significant improvement in low-temperature dryer performance with the introduction of cascade heat pump cycles.

关键词： Cascade cycle R134a/R404a Heat pump dryer COP Energy efficiency

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