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大口径光学二维角度调整机构的支承优化设计

机械设计与研究 2010年第5期26卷 79-83页

作者：沈丽丽章亚男上海大学机电工程与自动化学院上海200072

设计了"三顶三拉"的大口径光学二维角度调整机构,并探讨支承分布方式对基于三点支承调平机构的调整性能、抗倾覆能力和抗变形能力的影响,为机构设计提供了理论依据。分别建立了调平机构的几何模型、力学模型和优化模型。推导了支承调整... 详细信息

设计了"三顶三拉"的大口径光学二维角度调整机构,并探讨支承分布方式对基于三点支承调平机构的调整性能、抗倾覆能力和抗变形能力的影响,为机构设计提供了理论依据。分别建立了调平机构的几何模型、力学模型和优化模型。推导了支承调整量对平板二维倾角的贡献值,通过比较证明支承呈对称分布的调平机构更易达到快速调平的目的。介绍一种抗倾覆几何测度的概念,从中给出支承呈任意三角形分布的调平机构抗倾覆几何测度公式,并给出了对称分布调平机构的抗倾覆几何测度解析解。通过ANSYS优化模块对前内环的支承位置进行优化,得到最优的支承跨距。

关键词：调平机构调整性能抗倾覆能力支承分布

Correlation of ATP7B genotype with phenotype in Chinese patients with Wilson disease

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World Journal of gastroenterology 2004年第4期10卷 590-593页

作者： xiao-Qingliu ya-FenZhang Tze-Tzeliu Kwang-JenHsiao Jian-MingZhang Xue-Fangu Ke-RongBao li-HuaYu Mei-XianWang DepartmentofNeurology XinhuaHospitalShanghaiSecondMedicalUniversityShanghai200092China ShanghaiInstituteforPediatricResearch Shanghai200092China genomeResearchCenterandInstituteofgenetics NationalYangMingUniversityandDepartmentofMedicalResearchandEducationTaipeiVeteransGeneralHospitalTaipei11216TaiwanChina

AIM:To determine the mutational characterization of Ptype ATP7B gene and to explore the correlation of ATP7B genotype to phenotype in Chinese patients with Wilson disease (WD).METHODS: Seventy-five patients with WD from 72 no-kinship families,44 males and 31 females, were enrolled in this *** age of onset ranged from 4 to 39 years,≤18 years in 72 patients. Some exons of ATP7B gene mutations were analyzed in patients with WD by using biochemical methods,polymerase chain reaction-single strand configuration polymorphism (PCR-SSCP) and DNA sequence analysis. A total of 778 coding regions were identified with restriction enzyme Msp I. The activity of Cu-ATPase was assessed by measuring inorganic ***: Sixty-six of 75 patients (88%) had with hepatic manifestations, 39 of them had only hepatic manifestations,27 patients had hepatic and neurological manifestations or other symptoms at the same time (16 patients had associated neurological manifestation, 3 patients had osteopathy, 8 patients had other symptoms). Eight of the 75 patients (10.7%) had only neurological symptoms, one patient (5 years old) had no symptom. Twelve changing patterns were detected in ATP7B gene by DNA sequencing, induding seven mutations (R778L, C656X, g943D, V1140A, Vl106I V1216M and 1384de117), six polymorphisms (IVS4-5t/c, A2495g, C2310g,IVS18+6c/t and IVS20+5a/g). R778L occurred in 49/66 patients (74%) with hepatic manifestations, homozygosis of R778L in 16 patients, heterozygosity of R778L in 33 patients. V1106I mutation of ATP7B gene occurred in 2 patients with delaying onset of clinical symptoms. Cu-ATPase activity of three patients with known mutations (R778L/V1106I/A2495g, R778L/V1216M and R778L/R778L) were determined; and the activity of Cu-ATPase was decreased by 44.55%, 88.23% and 69.49% ***:1384del17bp is a novel mutation found in WD patients.R778L is the most common mutation of ATP7B gene. There is a correlation between R778L and hepatic manifest

关键词：肝豆状核变性 ATP7B基因 PCR-SSCP 基因多态性 DNA序列分析

Validation of Reliable Reference genes for Accurate Normalization in RT-qPCR Analysis of Codonopsis pilosula

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Chinese Herbal Medicines 2017年第3期9卷 226-235页

作者： ling-ya Cao Xiao-xiao li Dong Wang Hai-feng Sun Jian-ping gao School of Basic Medical Science Shanxi Medical University School of Pharmacy Shanxi Medical University College of Chemistry & Chemical Engineering Shanxi University

Objective To identify reliable reference genes（Rgs） for normalization of real-time PCR（RT-q PCR） data in Codonopsis pilosula. Methods The expression profiles of 10 candidate Rgs（gAPDH, ACT, α-TUB, β-TUB, UBQ, CYP, EF-1α, NAC, F-box and PP2A） were examined in C. pilosula during the phenological period. The raw materials examined included roots, stems, leaves, and flower buds at flowering and boll-forming stages, five growth stages of untreated and treated roots with plant growth retardant. The best-suited Rgs were accessed using ge Norm, NormF inder, Best Keeper, and Ref Finder algorithms. Results The best-ranked references genes differed across the samples. gAPDH and PP2A were the most suitable for expression analysis in untreated tissues while gAPDH, α-TUB, and PP2A were ranked as the three most stably expressed genes in untreated roots, while NAC and CYP were the most stably expressed genes in stressed（i.e., treated） roots. The expression of UgPase, a key enzyme for CPP biosynthesis, was determined to further validate the selected Rgs. Conclusion A total of 10 Rgs can be used as reference genes of C. pilosula, however the appropriate one should be used as it may chance.

关键词： Codonopsis pilosula normalization polysaccharide biosynthesis reference genes

Passivation of degradation path enables high performance perovskite nanoplatelet lasers with high operational stability

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Photonics Research 2022年第6期10卷 1440-1452页

作者： gUOHUI li HUIHUI PI yaNFU WEI BOliN ZHOU ya gAO RONg WEN YUYINg HAO HAN ZHANg BENg S.ONg yaNXIA CUI College of Physics and Optoelectronics Key Laboratory of Interface Science and Engineering in Advanced MaterialsKey Laboratory of Advanced Transducers and Intelligent Control System of Ministry of EducationTaiyuan University of TechnologyTaiyuan 030024China Collaborative Innovation Centre for Optoelectronic Science and Technology Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong ProvinceCollege of Physics and Optoelectronic EngineeringShenzhen Key Laboratory of Micro-Nano Photonic Information TechnologyGuangdong Laboratory of Artificial Intelligence and Digital Economy(SZ)Shenzhen UniversityShenzhen 518060China Department of Chemistry Research Centre of Excellence for Organic ElectronicsInstitute of Advanced MaterialsHong Kong Baptist UniversityKowloon TongHong KongChina

MAPbI_(3)perovskite has attracted widespread interests for developing low-cost near infrared semiconductor gain ***,it faces the instability issue under operation conditions,which remains a critical *** is found that the instability of the MAPbI_(3)nanoplatelet laser comes from the thermal-induced degradation progressing from the surface defects towards neighboring *** using PbI_(2) passivation,the defect-initiated degradation is significantly suppressed and the nanoplatelet degrades in a layer-by-layer way,enabling the MAPbI_(3)laser to sustain for 4500 s(2.7×10^(7) pulses),which is nearly three times longer than that of the nanoplatelet laser without ***,the PbI_(2) passivated MAPbI_(3)nanoplatelet laser with the nanoplatelet cavity displays a maximum quality factor up to∼7800,the highest reported for all MAPbI_(3)nanoplatelet ***,a high stability MAPbI_(3)nanoplatelet laser that can last for 8500 s(5.1×10^(7) pulses)is demonstrated based on a dual passivation strategy,by retarding the defect-initiated degradation and surface-initiated degradation *** work provides in-depth insights for understanding the operating degradation of perovskite lasers,and the dual passivation strategy paves the way for developing high stability near infrared semiconductor laser media.

关键词： stability initiated high

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激光等离子体光丝中太赫兹频谱的调控

物理学报 2020年第2期69卷 130-135页

作者：李晓璐白亚刘鹏中国科学院上海光学精密机械研究所强场激光物理国家重点实验室上海201800 中国科学院大学北京100049 上海交通大学IFSA协同创新中心上海200240

研究了双色激光场激发空气成丝产生太赫兹辐射频谱的变化规律.实验观察到随驱动光功率和光丝长度增加,太赫兹光谱主要发生红移的现象.分析表明,由于等离子体密度的增加,太赫兹辐射的趋肤深度减小,等离子体吸收主导了红移的发生.在光丝... 详细信息

研究了双色激光场激发空气成丝产生太赫兹辐射频谱的变化规律.实验观察到随驱动光功率和光丝长度增加,太赫兹光谱主要发生红移的现象.分析表明,由于等离子体密度的增加,太赫兹辐射的趋肤深度减小,等离子体吸收主导了红移的发生.在光丝足够短的条件下,趋肤深度远大于光丝长度,从而产生等离子体振荡主导的太赫兹辐射光谱蓝移.本研究为超快宽带太赫兹辐射的频谱调控提供了新思路.

关键词：太赫兹辐射激光等离子体等离子体频率等离子体吸收

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模糊DCPO范畴的一个笛卡尔闭的满子范畴

模糊系统与数学 2014年第6期28卷 9-15页

作者：刘妮胡亚立陕西师范大学数学与信息科学学院陕西西安710062

引入了有界完备模糊dcpo的概念,研究了有界完备模糊dcpo的基本性质。证明了当赋值格L是Frame时,以模糊Scott连续映射为态射的有界完备模糊dcpo范畴BC-FDCPO是以模糊Scott连续映射为态射的模糊dcpo范畴FDCPO的笛卡尔闭子范畴。同时还给... 详细信息

引入了有界完备模糊dcpo的概念,研究了有界完备模糊dcpo的基本性质。证明了当赋值格L是Frame时,以模糊Scott连续映射为态射的有界完备模糊dcpo范畴BC-FDCPO是以模糊Scott连续映射为态射的模糊dcpo范畴FDCPO的笛卡尔闭子范畴。同时还给出了模糊完备交半格、强模糊完备交半格的定义,并研究了它们与有界完备模糊dcpo之间的关系。

关键词：有界完备模糊dcpo 笛卡尔闭范畴模糊完备交半格模糊Scott连续映射

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一种基于FFT变换的超宽带信道盲估计算法

哈尔滨工程大学学报 2007年第9期28卷 1048-1051页

作者：窦峥郭黎利张雅彬哈尔滨工程大学信息与通信工程学院黑龙江哈尔滨150001

提出一种假设同步条件下,适合PPM调制的超宽带信道盲估计算法.算法基于接收信号的一维圆周平稳特性,结合圆周退卷积运算,达到对参数的估计目的.该算法只需简单的傅里叶变换运算和少量操作,具有低复杂度,易工程实现的优点.算法可同时对... 详细信息

提出一种假设同步条件下,适合PPM调制的超宽带信道盲估计算法.算法基于接收信号的一维圆周平稳特性,结合圆周退卷积运算,达到对参数的估计目的.该算法只需简单的傅里叶变换运算和少量操作,具有低复杂度,易工程实现的优点.算法可同时对多路信道进行估计,而且对幅度和相位不存在模糊因子.仿真结果表明,对于传输500个信息符号的信道估计结果,当系统误码率达到1‰时,与理想条件下接收机信噪比相差不到3 dB.

关键词：盲信道估计循环平稳脉位调制超宽带

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工件可拒绝平行机排序

郑州大学学报（理学版） 2010年第3期42卷 15-18,22页

作者：任立莉李娅李阳郑州大学数学系河南郑州450001

考虑工件有到达时间并且可拒绝的m台无界平行批处理机最小化最大完工时间的排序问题.如果拒绝一个工件,要花费一定的惩罚费用;如果接受这个工件,在m台机器中的一台上分批加工,定义一批的加工时间为这批中所包含的最长工件的加工时间.目... 详细信息

考虑工件有到达时间并且可拒绝的m台无界平行批处理机最小化最大完工时间的排序问题.如果拒绝一个工件,要花费一定的惩罚费用;如果接受这个工件,在m台机器中的一台上分批加工,定义一批的加工时间为这批中所包含的最长工件的加工时间.目标函数是最小化接受工件的最大完工时间与拒绝工件的费用之和.当m是一个给定的数时,给出了这个问题的一个拟多项式时间算法和一个完全多项式时间近似方案.

关键词：排序拒绝费用完全多项式时间近似算法

Temperature Effects on Photoluminescence Properties of Porous Silicon

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Semiconductor Photonics and Technology 2005年第4期11卷 228-232,238页

作者： li Zhi-quan QIAO Shu-xin CAI ya-nan TONg Kai ZHANg Le-xin Colle. of Electr. Eng. Yanshan University Qinhuangdao 066004 CHN Key Lab. of Metastable Mater. Sci. and Tech. Yanshan University Qinhuangdao 066004 CHN

The temperature effects on the photoluminescence(PL) properties of porous silicon(PS) have been observed in the early stage. However, the obtained results are different. Through repeated experiments, some different and useful information are got, which benefits us in that PL properties of porous silicon can be fully made use of. Firstly, samples with porosity of 76% and 49% were chosen to study the exciting temperature effects on the PL spectrum. For the samples with low porosity, the decreasing temperature causes the peak wavelength to be red-shifting and that of the samples with high porosity to present the blue-shifting trend. The light intensity of both reaches the maximum at -10℃. These experimental results can be well explained with the synthesized center PL model based on the quantum confinement model, other than the PL efficiency function σ(λ). Thereafter, PL properties of PS samples fabricated separately under the temperature of -10℃, 0℃, 10℃, 20℃ and 30℃ were studied. The results indicate that with the decrease of the etching temperature, the PL intensity increases from 406.7 to 716.6 and the peak wavelength blue-shifts from 698.9nm to 671.8nm. The WHFM of the PL spectrum dramatically narrows. At the same time, the images observed by AFM show that with the decreasing temperature, the holes are becoming deeper and the porosity is higher, which suggests that the decreasing temperature accelerates the etching rate.

关键词： Porous silicon PL Temperature effects Synthesized center PL model