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Effect of TiO2 pigment gradation on the properties of thermal insulation coatings

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International Journal of Minerals,Metallurgy and Materials 2016年第12期23卷 1466-1474页

作者： Lu-wei Shen ya-mei zhang Pei-gen zhang Jin-jie Shi Zheng-ming Sun Jiangsu Key Laboratory of Advanced Metallic Materials School of Materials Science and EngineeringSoutheast UniversityNanjing 211189China Jiangsu Key Laboratory of Construction Materials School of Materials Science and EngineeringSoutheast UniversityNanjing 211189China National Institute of Advanced Industrial Science and Technology(AIST) 16-1 OnogawaTsukubaIbaraki 305-8569Japan

This study was designed to evaluate the thermal performance and mechanical properties of coatings with different gradations of TiO2 pigments. The solar reflectance, cooling performance, wash resistance, and film adhesion strength of the coatings were investigated. The influence of TiO2 powder gradation on the final properties of the coatings was studed. The solar reflectance and the thermal insulation were observed to increase with increasing content of nanosized TiO2. The mechanical properties of the coatings, such as their wash resistance and film adhesion strength, were observed to increase with increased incorporation of nanosized TiO2. Such improvements in the properties of the coatings were attributed to the greater specific surface area and lower thermal conductivity of nanosized TiO2 particles compared to normal TiO2 particles.

关键词： gradation thermal insulation coatings performance titanium dioxide

Preparation and properties of thermal insulation coatings with a sodium stearate-modified shell powder as a filler

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International Journal of Minerals,Metallurgy and Materials 2017年第10期24卷 1192-1199页

作者： Qiang Tang ya-mei zhang Pei-gen zhang Jin-jie Shi Wu-bian Tian Zheng-ming Sun Jiangsu Key Laboratory of Construction Materials School of Materials Science and Engineering Southeast University Nanjing 211189 China Jiangsu Key Laboratory of Advanced Metallic Materials School of Materials Science and Engineering Southeast University Nanjing 211189 China

Waste shell stacking with odor and toxicity is a serious hazard to our living environment. To make effective use of the natural resources, the shell powder was applied as a filler of outdoor thermal insulation coatings. Sodium stearate(SS) was used to modify the properties of shell powder to reduce its agglomeration and to increase its compatibility with the emulsion. The oil absorption rate and the spectrum reflectance of the shell powder show that the optimized content of SS as a modifier is 1.5wt%. The total spectrum reflectance of the coating made with the shell powder that is modified at this optimum SS content is 9.33% higher than that without any modification. At the optimum SS content of 1.5wt%, the thermal insulation of the coatings is improved by 1.0℃ for the cement mortar board and 1.6℃ for the steel plate, respectively. The scouring resistance of the coating with the 1.5wt% SS-modified shell powder is three times that of the coating without modification.

关键词： heat insulation coatings shell powder sodium stearate scrub resistance

Ethanol extract of Herpetospermum caudigerum Wall ameliorates psoriasis-like skin inflammation and promotes degradation of keratinocyte-derived ICAM-1 and CXCL9

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Journal of Integrative Medicine 2023年第6期21卷 584-592页

作者： ya Zhong Bo-wen zhang Jin-tao Li Xin Zeng Jun-xia Pei ya-mei zhang Yi-xi yang Fu-lun Li Yu Deng Qi Zhao Engineering Research Center of Sichuan-Xizang Traditional Medicinal Plant Chengdu UniversityChengdu 610106Sichuan ProvinceChina Institute of Cancer Biology and Drug Discovery Chengdu UniversityChengdu 610106Sichuan ProvinceChina School of Food and Biological Engineering Chengdu UniversityChengdu 610106Sichuan ProvinceChina School of Pharmacy Chengdu UniversityChengdu 610106Sichuan ProvinceChina Key Laboratory of Clinical Genetics Affiliated Hospital of Chengdu UniversityChengdu 610106Sichuan ProvinceChina Department of Dermatology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China School of Basic Medical Sciences Chengdu UniversityChengdu 610106Sichuan ProvinceChina

Objective:To explore whether the ethanol extract of Herpetospermum caudigerum Wall(EHC),a Xizang medicinal plant traditionally used for treating liver diseases,can improve imiquimod-induced psoriasis-like skin ***:Immunohistochemistry and immunofluorescence staining were used to determine the effects of topical EHC use in vivo on the skin pathology of imiquimod-induced psoriasis in *** protein levels of interferon-γ(IFN-γ),tumor necrosis factor-a(TNF-a),and interleukin-17A(IL-17A)in mouse skin samples were examined using immunohistochemical *** vitro,IFN-γ-induced HaCaT cells with or without EHC treatment were used to evaluate the expression of keratinocyte-derived intercellular cell adhesion molecule-1(ICAM-1)and chemokine CXC ligand 9(CXCL9)using Western blotting and reverse transcription-quantitative polymerase chain *** protein synthesis inhibitor cycloheximide and proteasome inhibitor MG132 were utilized to validate the EHC-mediated mechanism underlying degradation of ICAM-1 and ***:EHC improved inflammation in the imiquimod-induced psoriasis mouse model and reduced the levels of IFN-γ,TNF-a,and IL-17A in psoriatic *** with EHC also suppressed ICAM-1 and CXCL9 in epidermal *** mechanistic studies revealed that EHC suppressed keratinocyte-derived ICAM-1 and CXCL9 by promoting ubiquitin–proteasome-mediated protein degradation rather than transcriptional *** primary compounds including ehletianol C,dehydrodiconiferyl alcohol,herpetrione,herpetin,herpetotriol,herpetetrone and herpetetrol were identified from the EHC using ultra-performance liquid chromatography-quadrupole-time of flight-mass ***:Topical application of EHC ameliorates psoriasis-like skin symptoms and improves the inflammation at the lesion sites.

关键词： Psoriasis Herpetospermum caudigerum wall Cytokines Degradation

Rufoolivacin B,a novel polyketide pigment from the fruiting bodies of the fungus Cortinarius rufo-olivaceus(basidiomycetes)

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Chinese Chemical Letters 2009年第11期20卷 1324-1326页

作者： An Ling zhang Jian Chun Qin Ming Sheng Bai Jin Ming Gao ya mei zhang Sheng Xiang yang Hartmut Laatsch College of Science Northwest A & F University Yangling Shaanxi 712100 China Department of Orgnic Chemistry University of Gottingen Tammannstrasse 2 D-3 7077 Gottingen Germany College of Life Sciences Northwest A & F University Yangling Shaanxi 712100 China Center for Experiments & Education Technology Linyi Normal University Linyi Shandong 276005 China

A novel polyketide pigment （1） with the 4＇,10-coupled linkage between 1-naphthalenol and 1,4-anthraquinone, named rufoolivacin B together with the known analog rufoolivacin （2）, has been isolated from the fruiting bodies of the Chinese toadstool Cortinarius rufo-olivaceus （basidiomycetes）. Their structures were characterized by means of analysis of spectroscopic methods, including 2D-NMR experiments and HR-ESI-MS.

关键词： Anthraquinone Polyketide Basidiomycetes Cortinarius rufo-olivaceus Fungal pigment Rufoolivacin B

Effects of Neuregulins on Invasion and Metastasis of Non-overexpression ErbB2 Breast Cancer Cells

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Chinese Journal of Cancer Research 2009年第2期21卷 115-121页

作者： ya-mei zhang Ting-ting Zhao Hua-yu Deng Laboratory of Stem Cell and Tissue Engineering Chongqing Medical University Chongqing 400016 China

Objective： To explore the effects of neuregulins on ErbB2 receptor signal transduction pathway activation, and invasion and metastasis of non-overexpression ErbB2 breast cancer cell MDA-MB-231. Methods： The expressions of neuregulin were detected by immunocytochemistry and Western blot. MDA-MB-231 cells were treated with ErbB2 kinase inhibitor AG825. Proliferations were measured with MTT assay. Invasion and metastasis of MDA-ME-231 cells were evaluated with transwell chamber. The enzyme activities of MMP-2 and MMP-9 were detected by gelatin zymography. The expressions of MMP-2 and HIF-1α were detected by Western blot. Results： MDA-MB-231 cells expressed a relatively higher level of neuregulin. In Western blot, the positive reaction band was found at 44KD which coincides with the molecular weight of NRG. When MDA-MB-231 cells were treated with AG825, the proliferation was inhibited in a time-dose-dependent manner （P〈0.01）, invasion and metastasis were also depressed （P〈0.05）. The enzyme activities of MMP-2 and MMP-9 were lower （P〈0.05）. The expression levels of MMP-2 and HIF-lct were decreased （P〈0.05）. Conclusion： Our study indicates that neuregulins are synthesized in MDA-MB-231 cells as transmembrane proteins, neuregulins could activate ErbB2 receptor signal transduction pathway by autocrine or paracrine secretion, and induce invasion and metastasis of MDA-MB-231 cells.

关键词： Non-overexpression ErbB2 breast cancer Neuregulins Invasion Metastasis

Value of serum procalcitonin content in severe acute pancreatitis for evaluating the infection degree and intestinal mucosal barrier function

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Journal of Hainan Medical University 2018年第4期24卷 100-103页

作者： Jing Gao Xi Chen mei yang ya-mei zhang Department of Laboratory Medicine Mianyang Central Hospital in Sichuan ProvinceMianyangSichuan Province621000 Ophthalmology Department Mianyang Central Hospital in Sichuan ProvinceMianyangSichuan Province621000

Objective: To explore the value of serum procalcitonin content in severe acute pancreatitis for evaluating the infection degree and intestinal mucosal barrier function. Methods: A total of 68 patients with severe acute pancreatitis who were treated in our hospital between January 2015 and September 2017 were selected as pancreatitis group, and 50 healthy volunteers who underwent physical examination in this hospital during the same period were selected as normal control group. The differences in serum levels of PCT, inflammatory factors and intestinal mucosal barrier function indexes were compared between the two groups, and Pearson test was used to evaluate the correlation between PCT content and severe acute pancreatitis. Results: Serum PCT content of pancreatitis group was higher than that of control group;serum IL-6, IL-10 and TNF-α contents were higher than those of control group;serum D-Lactate, DAO and Endotoxin contents were higher than those of control group. Pearson test showed that the serum PCT content of patients with severe acute pancreatitis was directly correlated with the degree of infection and intestinal mucosal barrier dysfunction. Conclusion:Serum PCT content abnormally increases in severe acute pancreatitis, and the specific content is directly correlated with the degree of infection and intestinal mucosal barrier dysfunction.

关键词： Severe acute pancreatitis Procalcitonin Inflammatory response Intestinal mucosal barrier function

Pneumomediastinum Secondary to Foreign Body Aspiration： Clinical Features and Treatment Explorement in 39 Pediatric Patients

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Chinese Medical Journal 2016年第22期129卷 2691-2696页

作者： Xiao-Jian yang Jie zhang Ping Chu Yong-Li Guo Jun Tai ya-mei zhang Li-Xing Tang Xin Ni Department of Otolaryngology-Head and Neck Surgery Beijing Children's Hospital Capital Medical University Beijing 100045 China Beijing Key Laboratory for Pediatric Diseases of Otolaryngology-Head and Neck Surgery Beijing Pediatric Research Institute Capital Medical University Beijing 100020 China

Background：Pneumomediastinum （PM） secondary to foreign body aspiration （FBA） is rare in *** it is mainly benign,some cases may be *** to the rare nature of this clinical entity,proper assessment and management have been poorly studied so ***,we characterized the presentation and management of this clinical entity and provided an evaluation system for the ***：We retrospectively reviewed children with PM secondary to FBA,who were treated in Beijing Children＇s Hospital from January 2010 to December *** patients were stratified according to the degree of dyspnea on admission,and interventions were given *** removals of airway foreign bodies （FBs） were performed on all *** patients in acute respiratory distress,emergent air evacuation and/or resuscitations were performed *** data,interventions,and clinical outcomes were ***：A total of 39 patients were included in this *** clinical severity was divided into three grades （Grades Ⅰ,Ⅱ,and Ⅲ） according to the degree of ***-one patients were in Grade Ⅰ dyspnea,and they simply underwent bronchoscopic FBs *** resolved spontaneously and all patients recovered *** patients were in Grade Ⅱ dyspnea,and emergent drainage preceded rigid *** all recovered uneventfully under close *** exhausted patients were in Grade Ⅲ *** died from large PM and bilateral pneumothorax,respectively,despite of aggressive interventions in our ***：PM secondary to FBA could be life-threatening in some *** degree of dyspnea should be evaluated immediately,and patients in different dyspnea should be treated *** patients in Grade Ⅰ dyspnea,simple bronchoscopic FBs removals could promise a good *** patients in Grade Ⅱ dyspnea,emergent air evacuation and/or resuscitation should precede a bronchoscopy before the children become exhausted.

关键词： Children Foreign Body Aspiration Pneumomediastinum Pneumothorax Subcutaneous Emphysema

Acrylamide impairs adult neurogenesis and influence the expression of proliferation-associated genes in mouse hippocampus

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Acrylamide impairs adult neurogenesis and influence the expr...

Prevalence of Helicobacter pylori infection in Chinese military personnel:A cross-sectional,multicenter-based study

中国神经科学学会第十届全国学术会议

作者： Jiu-Tao WANG Wei zhang Run-Chuan yaN Xin-De HU Ling-Zhen SONG ya-mei zhang Shu-Lin CHEN Shan-Ting ZHAO College of Veterinary Medicine Northwest A＆F University

To investigate the influence of acrylamide poisoning on the adult neurogenesis and expression of prohferation-associated genes in the mouse dentate gyrus,adult male Kunming mice were used and divided into two groups:control group and experimental poisoning groups,that were exposured to acrylamide by intraperitoneal *** and Brdu labehng was used to investigate the prohferation of adult neural stem cells in the *** expression of prohferation-associated genes were examined by using *** results showed that the number of BrdU-positive cells in experimentally poisoning mice were remarkably decreased compared with that in the control group（P ＜0.01）.The mRNA expression levels of Gsk-3β,***,JNK3 and Racl were significantly increased in poisoning group compared to those in control *** results suggested that acrylamide poisoning suppressed the prohferation of adult neural stem cells and influenced the mRNA expression of ***-3β.Rac1 and RhoA in mice hippocampus.

关键词： acrylamide poisoning adult neurogenesis immunohistochemistry proliferation-associated gene

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World Journal of Gastroenterology 2025年第3期31卷 42-49页

作者： Han-Chen Min Chun-yan zhang Fang-Yu Wang Xiao-Hui Yu Shan-Hong Tang Hong-Wu Zhu ya-Gang Zhao Ji-Luo Liu Jian Wang Jing-Han Guo Xiao-mei zhang Yun-Sheng yang Chinese People’s Liberation Army Medical School Chinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology and Hepatology The First Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Sixth Healthcare Department The Second Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation ArmyLanzhou 730050Gansu ProvinceChina Department of Gastroenterology General Hospital of Western Theater CommandChengdu 610011Sichuan ProvinceChina Department of Gastroenterology General Hospital of Southern Theater CommandGuangzhou 510010Guangdong ProvinceChina Department of Epidemiology Naval Medical UniversityShanghai 200433China School of Medicine Nankai UniversityTianjin 300071China National Clinical Research Center for Geriatric Diseases Chinese People’s Liberation Army General HospitalBeijing 100853China

BACKGROUND Helicobacter pylori(***)infection is a prevalent disease encountered in military internal medicine and recognized as the main cause of dyspepsia,gastritis,and peptic ulcer,which are common diseases in military *** guidelines in China state all patients with evidence of active infection with *** are offered ***,the prevalence of *** infection and its regional distribution in the military population remain unclear,which hinders effective prevention and treatment *** the prevalence of *** infection in the military population will aid in the development of customized strategies to better manage this infectious *** To investigate the prevalence of *** infection in the Chinese military population in different geographic *** This multicenter,retrospective study included 22421 individuals from five tertiary hospitals located in north,east,southwest,and northwest cities of *** infection was identified using the urea breath test,which had been performed between January 2020 and December *** Of the 22421 military service members,7416(33.1%)were urea breath *** highest prevalence of *** was in the 30-39 years age group for military personnel,with an infection rate of 34.9%.The majority of infected subjects were younger than 40-years-old,accounting for 70.4%of the infected *** individuals serviced in Lanzhou and Chengdu showed a higher infection prevalence than those in Beijing,Nanjing,and Guangzhou,with prevalence rates of 44.3%,37.9%,29.0%,31.1%,and 32.3%,*** *** infection remains a common infectious disease among military personnel in China and has a relatively high prevalence rate in northwest China.

关键词： Helicobacter pylori Prevalence Military personnel Urea breath test Multicenter study