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The development of laminin-alginate microspheres encapsulated with Ginsenoside Rg1 and ADSCs for breast reconstruction after lumpectomy

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Bioactive Materials 2021年第6期6卷 1699-1710页

作者： I-Hsuan yang Yo-Shen Chen Jia-Jing Li ya-jyun liang Tzu-Chieh Lin Subhaini Jakfar Minal Thacker Shinn-Chih Wu Feng-Huei Lin Department of Biomedical Engineering College of Medicine and College of EngineeringNational Taiwan UniversityNo.49Fanglan RdTaipei10672China Division of Plastic Surgery Department of SurgeryFar Eastern Memorial HospitalNo.21Sec.2Nanya S.Rd.New Taipei City220China Department of Animal Science and Technology National Taiwan UniversityNo.1Section 4Roosevelt RoadTaipei City10617China Institute of Biomedical Engineering and Nanomedicine National Health Research InstitutesNo.35Keyan RoadZhunanMiaoli County35053China

Many technologies have been developed for breast reconstruction after *** the technologies achieved promising success in clinical,there are still many shortages hanging over and trouble the *** engineering technology was introduced to plastic surgery that gave a light to lumpectomy patients in breast *** unexpected absorption rate,resulting from limited vascularization and low cell survival rate,is a major factor that leads to unsatisfactory results for the previous studies in our *** the study,the laminin-modified alginate synthesized by a new method of low concertation of sodium periodate would be mixed with ADSCs and Rg1 in the medium;and then sprayed into a calcium chloride(CaCl2)solution to prepare into microsphere(abbreviated as ADSC-G-LAMS)by bio-electrospray with a power syringe for the mass production and smaller bead *** developed ADSC-G-LAMS microspheres had the diameter of 232±42μ***-release of the Rg1 retained its biological ***-1,live/dead staining,and chromosome aberration assay were evaluated to confirm the safety of the *** in vivo study,ADSC-G-LAMS microspheres combined with autologous adipocytes were transplanted into the dorsum of rats by subcutaneous *** efficacy was investigated by H&E and immunofluorescence *** results showed that the bioactive ADSC-G-LAMS microspheres could integrate well into the host adipose tissue with an adequate rate of angiogenesis by constantly releasing Rg1 to enhance the ADSC or adipocyte survival rate to join tissue growth and repair with adipogenesis for breast reconstruction after lumpectomy.

关键词： Laminin-alginate microspheres Adipose-derived stem cells Ginsenoside Rg1 Bio-electrospray Tissue engineering

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Analysis of the one-decoy-state SARG04 quantum cryptography protocol in the presence of afterpulse effects

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Communications in Theoretical Physics 2024年第6期76卷 66-71页

作者： Hu Nian ya-Feng Nie Chun-Mei Zhang liang-liang Lu Key Laboratory of Optoelectronic Technology of Jiangsu Province School of Physical Science and TechnologyNanjing Normal UniversityNanjing 210023China Institute of Quantum Information and Technology Nanjing University of Posts and TelecommunicationsNanjing 210003China Hefei National Laboratory Hefei 230088China

The SARG04 quantum key distribution protocol can offer greater robustness against photon number splitting attacks than the BB84 protocol that is implemented with weak *** this paper,we propose a tight key analysis for the SARG04 protocol,by considering the one-decoy method and investigating its performance under the influence of a detector *** results demonstrate that an increase in block size leads to a slight increase in both the secure key rate and the maximum transmission ***,the detector afterpulse plays a crucial role in practical applications and has a more pronounced effect on the SARG04 protocol compared to the BB84 protocol.

关键词： Quantum key distribution SARG04 protocol one decoy afterpulse

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On a Flexible Loan Repayment Method Depending on Borrower's Asset with an Early Termination Clause

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 557-567页

作者： Jin liang Jia-qi MAO Zhao-ya LIU School of Mathematical Sciences Tongji UniversityShanghai 200092China

Aiming at the problem that the asset’s fluctuation influences the borrower’s repayment ability,a loan with a new and flexible repayment method is designed,which depends on the asset value of the *** repayment method can reduce the loan default probability,but it causes the uncertainty of the pay off *** the repayment term is related to the regular repayment amount in this method,a boundary for the regular repayment amount is set up in order to avoid too long repayment *** will balance the benefit of borrowers and lenders and improve the applicability of this *** establishing a mathematical model of the residual value of the loan,this model can be transformed into an initial-boundary problem of a partial differential *** analytic solution and the expected time to pay off the loan are ***,numerical analysis are shown.

关键词： flexible repayment method repayment ratio early termination clause expected pay off time

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Ligand-controlled NiH-catalyzed regiodivergent hydroalkylation of 2-alkenylazaarenes

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Science China Chemistry 2024年第6期67卷 1935-1940页

作者： ya-Ping Shao Zhuo-Min Chi Yong-Min liang State Key Laboratory of Applied Organic Chemistry School of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou730000China

A nickel-hydride(Ni H)-catalyzed migratory and nonmigratory hydroalkylation reaction of 2-alkenyl azaarenes with alkyl iodines has been established through strategic modulation of N-or P-donor *** method enables the synthesis of diverseβ-orγ-branched aromatic *** mild regiodivergent protocols exhibit wide substrate scope,excellent functional tolerance,and great reaction yield with remarkable ***,deuterium labeling studies reveal Ni H-catalyzed interrupted chain-walking mode as the mechanism behind remotedβ-selective hydroalkylation reaction—an interesting phenomenon mediated through aromatic imine directing groups.

关键词： NiH regiodivergent hydroalkylation azaarenes interrupted chain-walking

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Cracking on a nickel-based superalloy fabricated by direct energy deposition

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China Foundry 2024年第4期21卷 311-318页

作者： Xue Zhang ya-hang Mu liang Ma Jing-jing liang Yi-zhou Zhou Xiao-feng Sun Jin-guo Li School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China Shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering Northeastern UniversityShenyang 110819China

Cracks have consistently been a significant challenge limiting the development of additive manufactured nickel-based *** is essential to investigate the location of cracks and their forming *** study extensively examines the impact of solidification process,microstructural evolution,and stress concentration on crack initiation during direct energy deposition(DED).The results emphasize that the crack formation is significantly related to large-angle grain boundaries,rapid cooling *** caused by large-angle grain boundaries and a fast-cooling rate predominantly appear near the edge of the deposited *** cracks are more likely to form near the top of the deposited sample,due to the presence ofγ/γ'*** secondary dendritic arm and the carbides in the interdendritic regions can obstruct liquid flow during the final stage of solidification,which results in the formation of solidification cracks and *** work paves the way to avoid cracks in nickel-based superalloys fabricated by DED,thereby enhancing the performance of superalloys.

关键词： location cracks direct energy deposition nickel-based superalloys

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Engineering FeOOH/Ni(OH)_(2) heterostructures on Ni_(3)S_(2)surface to enhance seawater splitting

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Rare Metals 2024年第5期43卷 1989-1998页

作者： Chen yang ya-Dong Li Li-Juan Cao Xi-Long Wang Han-Pu liang Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of SciencesQingdao 266101China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China Sino-Danish College University of Chinese Academy of SciencesBeijing 100049China

The construction of highly stable and efficient electrocatalysts is desirable for seawater splitting but remains challenging due to the high concentration of Cl-in ***,FeOOH/Ni(OH)_(2)heterostructure supported on Ni_(3)S_(2)-covered nickel foam(Fe–Ni/Ni_(3)S_(2)/NF)was fabricated by hydrothermal and etching methods,as well as anodic oxidation *** electronic structure of FeOOH and Ni(OH)_(2)could be modulated after depositing FeOOH nanoparticles on Ni(OH)_(2)nanosheet,which greatly boosted the catalytic *** the catalyst used as an electrode for oxygen evolution reaction(OER),it needed low overpotentials of 266 and 368 m V to achieve current densities of 100 and 800 m A·cm^(-2),respectively,in 1 mol·L^(-1)KOH+seawater *** can operate continuously at 100 m A·cm^(-2)for 400 h without obvious ***,in situ generated SO_(4)^(2-)from inner Ni_(3)S_(2)during electrolysis process would accumulate on the surface of active sites to form passivation layers to repel Cl^(-),which seemed to be responsible for superior *** study not only synthesizes an OER catalyst for highly selective and stable seawater splitting,but also gives a novel approach for industrial hydrogen production.

关键词： Anodic oxidation Heterostructure Oxygen evolution reaction Seawater splitting

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Hourly land surface temperature retrieval over the Tibetan Plateau using Geo-LightGBM framework: Fusion of Himawari-8 satellite, ERA5 and site observations

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Advances in Climate Change Research 2024年第4期15卷 623-635页

作者： Zhao-Hua LIU Shan-Shan WENG Zhao-liang ZENG Ming-Hu DING ya-Qiang WANG Zhehao liang Civil and Surveying&Mapping Engineering Jiangxi University of Science and TechnologyGanzhou 341000China State Key Laboratory of Severe Weather Chinese Academy of Meteoroogical Sciences Beijing 100081China Space Geodesy and Geoinformation Technical Unviersity of BerlinBerlin 10623Germany

The Tibetan Plateau(TP)is highly sensitive to even minor fluctuations in land surface temperature(LST),which can result in permafrost melting and degradation of alpine grasslands,leading to serious ecological ***,it is crucial to have high-temporal-resolution and seamless hourly estimating and monitoring of LST for a better understanding of climate change on the ***,we employed Himawari-8 satellite,Digital Elevation Model(DEM),ERA5 reanalysis and meteorological station observations data to develop a new LightGBM framework(called Geo-LightGBM)for estimating LST on the TP,and then analyzed the spatiotemporal variations of those ***-LightGBM demonstrated excellent LST estimation accuracy,with an R2(coefficient of determination)of 0.971,RMSE(root-mean-square error)of 2.479℃,and MAE(mean absolute error)of 1.510℃.The estimated LST values for the year 2020 agreed well with observed values,with remarkable differences in hourly LST ***,the estimated LST was more accurate than that from ***,there were two high LST centers,located in the yarlung Zangbo River Basin and the Qaidam Basin,and a low LST center located in the central *** SHAP(SHapley Additive exPlanations)and correlation analyses revealed DSCS(the mean ground downward shortwave radiation under clear-sky conditions)to be the most importantly input variable for estimating *** dummy variables(e.g.,longitude,latitude,DEM)were also found to be crucial for model accuracy *** findings indicate the potential for constructing a high-precision and seamless 24-h LST real-time retrieval and monitoring platform for the TP by combining satellite and China's independently developed CLDAS(China Land Data Assimilation System)data in future.

关键词： Tibetan Plateau Himawari-8 ERA5 Land surface temperature Geo-LightGBM

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Triggering triplet excitons of carbon nanodots through nanospace domain confinement for multicolor phosphorescence in aqueous solution

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Nano Research 2024年第7期17卷 6534-6543页

作者： ya-Chuan liang Qing Cao Yuan Deng Yong Wang Kai-Kai Liu Chong-Xin Shan School of Electronics and Information Zhengzhou University of Light IndustryZhengzhou 450002China Henan Key Laboratory of Diamond Optoelectronic Material and Devices Key Laboratory of Material PhysicsMinistry of EducationSchool of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450001China Academy for Quantum Science and Technology Zhengzhou University of Light IndustryZhengzhou 450002China Institute of Quantum Materials and Physics Henan Academy of SciencesZhengzhou 450046China

Easy non-radiative decay property of long-lived triplet excitons in aqueous solution obstructs their applications in aquatic *** reported phosphorescence phenomena in aqueous solution have excited researchers enormously but achieving full-color water-soluble phosphorescent carbon nanodots(CNDs)is still a challenging ***,full-color phosphorescence of water-soluble CNDs has been demonstrated by triggering their triplet excitons through nanospace domain confinement,and Förster energy resonance transfer is used for further tuning phosphorescence *** phosphorescence spans across most of the visible spectrum,ranging from 400 to 700 *** an aqueous solution,the CNDs exhibits blue,green,and red phosphorescence,lasting for approximately 6,10,and 7 s,***,the phosphorescence quantum yields are 11.85%,8.6%and 3.56%,making them readily discernible to the naked eyes and laying a solid foundation for practical ***,phosphorescence flexible optical display and bioimaging have been demonstrated by using the multicolor CNDs-based nanomaterials,showing distinct superiority for accuracy and complete display and imaging in complex emission background.

关键词： carbon nanodots triplet excitons multicolor aqueous solution

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Energy saving analysis for CO_(2)–O_(2)mixed injection technology in converter steelmaking

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Journal of Iron and Steel Research International 2024年第5期31卷 1095-1103页

作者： Bao-chen Han Chun-liang Gao ya-qiang Li Dan Liu Guang-sheng Wei Rong Zhu Hebei Key Laboratory of Material Near-Net Forming Technology School of Material Science and EngineeringHebei University of Science and TechnologyShijiazhuang050018HebeiChina Department of Automotive Engineering Hebei Vocational University of Technology and EngineeringXingtai054000HebeiChina School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing100083China

Energy-saving in China's iron and steel industry still relies on the development and improvement of short-term energy saving ***,a special converter smelting technology incorporating energy saving was *** evaluate the energy-saving potential of the CO_(2)–O_(2)mixed injection(COMI)technology,collected production data were used to develop an improved techno-economic *** reveal that the technology can save energy through auxiliary material consumption,sensible heat of solid by-product,iron loss reduction,and energy *** application of COMI technology in an enterprise is cost effective,involving the energy saving potential of 0.206 GJ/t,the cost of conserved energy of−48.83 yuan/GJ,and a simple payback period of 0.35 year for a 60-million-yuan *** analysis shows that the investment cost and discount rate primarily influence the cost of conserved energy of the *** the discount rate increased,the cost of conserved energy also gradually ***,the COMI technology is an energy-saving technology with good development prospects.

关键词： Converter steelmaking COMI technology Energy saving Techno-economic model Investment cost

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Unlocking the potential:How acupuncture reshapes the liver-centered lipid metabolism pattern to fight obesity

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Journal of Integrative Medicine 2024年第5期22卷 523-532页

作者： Shu-rui yang Li Chen Dan Luo ya-yuan Wang Feng-xia liang College of Acupuncture and Orthopedics Hubei University of Chinese MedicineWuhan 430061Hubei ProvinceChina Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion Wuhan 430061Hubei ProvinceChina Hubei Shizhen Laboratory Wuhan 430060Hubei ProvinceChina Hubei International Science and Technology Cooperation Base of Preventive Treatment by Acupuncture and Moxibustion Wuhan 430061Hubei ProvinceChina Acupuncture and Moxibustion Department Affiliated Hospital of Hubei University of Chinese Medicine(Hubei Provincial Hospital of Traditional Chinese Medicine)Wuhan 430060Hubei ProvinceChina

Obesity,a widespread global health issue,is frequently linked to disrupted lipid metabolism,resulting in excessive accumulation of adipose tissue and associated health ***,a traditional Chinese medical modality,has exhibited potential as a viable intervention for addressing *** underlying mechanism proposed involves the stimulation of specific acupoints to exert a regulatory influence on hepatic *** liver has a central role in lipid metabolism,including processes such as lipid synthesis,storage and *** is believed to enhance the liver’s efficiency in processing lipids,thereby reducing lipid accumulation and improving metabolic *** indicates that acupuncture can influence the expression of certain genes and proteins involved in lipid metabolism in the *** includes upregulating genes that promote lipid breakdown and oxidation,and downregulating those involved in lipid ***,acupuncture has been shown to improve insulin sensitivity,which is crucial for the regulation of lipid ***,the potential anti-inflammatory effects of acupuncture may play a significant role in its efficacy for the treatment of *** presence of chronic inflammation has been strongly associated with metabolic disorders such as *** its ability to mitigate inflammation,acupuncture can potentially aid in the restoration of lipid metabolism and the reduction of body ***,the amelioration of hepatic oxidative stress represents another mechanism by which acupuncture may contribute to the reduction of lipid ***,the liver,being the primary site of lipid metabolism,maintains communication with various organs including the brain,adipose tissue,skeletal muscle and *** perspective opens new avenues for the treatment of obesity,emphasizing the importance of holistic approaches in managing complex metabolic disorders.

关键词： Acupuncture Obesity Liver-centered lipid metabolism pattern

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