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Acta Mathematica Sinica,English Series 2014年第10期30卷 1689-1697页

作者： Zhe DONG ya fei zhao Department of Mathematics Zhejiang University

In this note, we show that avon Neumann algebra M is injective if and only if the weak＊ similarity degree d.（M） ≤ 2.

关键词： Weak* similarity degree injective von Neumann algebra operator space

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Nuclearity and Finite-Representability in the System of Completely Integral Mapping Spaces

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1197-1214页

作者： Zhe DONG Ji Cheng TAO ya fei zhao Department of Mathematics Zhejiang UniversityHangzhou 310027P.R.China Department of Mathematics China Jiliang UniversityHangzhou 310018P.R.China Department of Mathematics Zhejiang International Studies UniversityHangzhou 310023P.R.China

In this paper,we investigate local properties in the system of completely integral mapping *** introduce notions of injectivity,local reflexivity,exactness,nuclearity,finite-represent ability and WEP in the system of completely integral mapping *** we obtain that any finite-dimensional operator space is injective in the system of completely integral mapping *** we prove that C is the unique nuclear operator space and the unique exact operator space in this *** also show that C is the unique operator space which is finitely representable in{T_(n)}n∈Nin this *** corollaries,Kirchberg’s conjecture and QWEP conjecture in the system of completely integral mapping spaces are false.

关键词： Completely integral mapping space injectivity exactness nuclearity finite-representability WEP

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Clinical and laboratory features of newly diagnosed multiple myeloma:a retrospective,single-centre analysis

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Chinese Medical Journal 2007年第19期120卷 1727-1729页

作者： MAI Yu-jie QI Pei-jing XU yan ZOU De-hui WANG ya-fei zhao yao-zhong yaNG Ren-chi XIAO Zhi-jian QIU Lu-gui Institute of Hematology ＆ Blood Disease Hospital Chinese Academy of Medical Sciences ＆ Peking Union of Medical College Tianjin 300020 China

Multiple myeloma （MM）, a common malignant plasma-cell proliferative disease, accounts for more than 10% of hematologic malignancies. There have been many studies conducted to analyze the clinical and laboratory features of patients with MM. The purpose of this study was to determine the clinical and laboratory features of patients with newly diagnosed MM in a large cohort of consecutive patients seen at the Blood Disease Hospital of Chinese Academy of Medical Swence during a 13-year period.

关键词： multiple myeloma diagnosis survival

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Precise gradient separation of nanoparticles using reduced graphene oxide-polyoxomolybdate membranes

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Science China Chemistry 2025年第01期 209-216页

作者： Yixin yang Wanlei zhao Ruoxuan Zheng Hongqiang Li Wei Chen Yu-fei Song State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology Quzhou Institute for Innovation in Resource Chemical Engineering

The purification and size sieving of nanoparticles （NPs） represents a significant scientific ***,the r GO-polyoxometalates (POMs=PMo12,Mo132and Mo368) membranes were fabricated successfully via a simple and scalable POMsassisted in-situ photoreduction *** the mass ratio of r GO to PMo12was 1:30,the resultant r GO-PMo12membranes with highly ordered and uniform nanochannels of 1.0 nm can be obtained,which showed an accurate carbon quantum dots（CQDs） separation with a cut-off size approximately 1.0 *** increase of the size of the interlayered POMs from PMo12（1.0 nm）,{Mo132}（2.9 nm） to{Mo368}（3.8 nm）,the resultant r GO-PMo12,r GO-Mo132and r GO-Mo368exhibited precise gradient separation of CQDs and Au nanoparticles by size exclusion *** results pave a promising way to construct new twodimensional （2D） membranes for highly efficient size-selective separation.

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Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan zhao Yidan Zhang Xin Liu Jian Zhang ya Gao Shuyue Li Cui Chang Xiang Liu Guofeng yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

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Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex

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Neural Regeneration Research 2025年第10期20卷 2923-2937页

作者： yan Li Peng Hao Hongmei Duan fei Hao Wen zhao Yudan Gao zhaoyang yang Kwok-Fai So Xiaoguang Li Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina China Rehabilitation Science Institute China Rehabilitation Research CenterBeijing Key Laboratory of Neural Injury and RehabilitationBeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Beijing Key Laboratory for Biomaterials and Neural Regeneration School of Engineering MedicineBeihang UniversityBeijingChina Guangdong-HongKong-Macao Institute of CNS Regeneration Ministry of Education CNS Regeneration Collaborative Joint LaboratoryJinan UniversityGuangzhouGuangdong ProvinceChina Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) GuangzhouGuangdong ProvinceChina Department of Ophthalmology and State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong Kong Special Administration RegionChina Center for Brain Science and Brain-Inspired Intelligence Guangdong-HongKong-Macao Greater Bay AreaGuangzhouGuangdong ProvinceChina Co-innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Biomedical Engineering School of Biological Science and Medical EngineeringBeihang UniversityBeijingChina

The presence of endogenous neural stem/progenitor cells in the adult mammalian brain suggests that the central nervous system can be repaired and regenerated after ***,whether it is possible to stimulate neurogenesis and reconstruct cortical layers II to VI in non-neurogenic regions,such as the cortex,remains *** this study,we implanted a hyaluronic acid collagen gel loaded with basic fibroblast growth factor into the motor cortex immediately following traumatic *** findings reveal that this gel effectively stimulated the proliferation and migration of endogenous neural stem/progenitor cells,as well as their differentiation into mature and functionally integrated ***,these new neurons reconstructed the architecture of cortical layers II to VI,integrated into the existing neural circuitry,and ultimately led to improved brain *** findings offer novel insight into potential clinical treatments for traumatic cerebral cortex injuries.

关键词： adult endogenous neurogenesis basic fibroblast growth factor-hyaluronic acid collagen gel cortical remodeling functional recovery migration motor cortex injury neural circuits neural stem cells newborn neurons proliferation

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某发动机弹性密封贴合面轴向变形量计算

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风机技术 2023年第5期65卷 81-84页

作者：周龙超赵亚飞赵丹诚中国航空发动机集团公司四川燃气涡轮研究院深圳大学电子与信息工程学院

为准确、定量评估某发动机弹性密封件贴合面的轴向变形,首先建立贴合组件的模型,随后对模型中的各零部件赋予导热系数与材料,施加初始温度、换热系数等边界条件,计算出四种恶劣工况下精确的温度场分布,随后将温度场分布作为输入条件导... 详细信息

为准确、定量评估某发动机弹性密封件贴合面的轴向变形,首先建立贴合组件的模型,随后对模型中的各零部件赋予导热系数与材料,施加初始温度、换热系数等边界条件,计算出四种恶劣工况下精确的温度场分布,随后将温度场分布作为输入条件导入结构求解的模型中求解,输入材料的热膨胀系数和弹性模量,施加轴向力载荷时考虑2g的正反方向的过载,分别求出极限情况下的两个大的组件中端面的轴向变形,最后进行求差,得到最大的轴向相对变形量,从而为进一步评估压缩量对弹性密封的影响提供了科学的定量依据。

关键词：弹性密封贴合面变形量温度场过载相对变形量

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应激与肠道疾病发生机制

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世界华人消化杂志 2020年第14期28卷 617-627页

作者：李佳佳任文静尹海燕赵亚飞唐勇成都中医药大学针灸推拿学院四川省成都市610075 针灸与时间生物学四川省重点实验室四川省成都市610075

应激是机体在生存竞争中的一种本能的防御机制;但长期、慢性应激则会引起全身多系统多部位病理表现.肠道疾病与机体受到的应激关系密切.本文重点就心理应激引起肠道疾病发生的下丘脑-垂体-肾上腺轴、自主神经系统和肠道自身介导发生机... 详细信息

应激是机体在生存竞争中的一种本能的防御机制;但长期、慢性应激则会引起全身多系统多部位病理表现.肠道疾病与机体受到的应激关系密切.本文重点就心理应激引起肠道疾病发生的下丘脑-垂体-肾上腺轴、自主神经系统和肠道自身介导发生机制进行综述.

关键词：肠道疾病心理应激下丘脑-垂体-肾上腺轴交感神经迷走神经肠道

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牙龈卟啉单胞菌侵入口腔上皮细胞后基因表达变化的初步研究

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牙体牙髓牙周病学杂志 2012年第11期22卷 641-645页

作者：成伟王洁孔令雪齐霞吴亚菲赵蕾四川大学口腔疾病研究国家重点实验室四川成都610041 四川大学华西口腔医院牙周科四川成都610041

目的:采用差异显示反转录PCR技术,比较牙龈卟啉单胞菌侵入口腔上皮细胞后基因表达的变化,初步筛选与细菌侵入宿主细胞相关的毒力致病基因。方法:提取纯培养状态和侵入KB细胞后的牙龈卟啉单胞菌ATCC 33277细菌总RNA;反转录PCR技术显示cDN... 详细信息

目的:采用差异显示反转录PCR技术,比较牙龈卟啉单胞菌侵入口腔上皮细胞后基因表达的变化,初步筛选与细菌侵入宿主细胞相关的毒力致病基因。方法:提取纯培养状态和侵入KB细胞后的牙龈卟啉单胞菌ATCC 33277细菌总RNA;反转录PCR技术显示cDNA表达条带;筛选并回收差异表达条带,二次扩增cDNA,经测序和BLAST同源性比对,初步分析细菌侵入KB细胞后表达差异基因的功能。结果:共筛选获得3条牙龈卟啉单胞菌侵入KB细胞后表达存在差异的基因HX 01、HX 02、HX 03;BLAST同源性比对结果显示,HX 01与牙龈卟啉单胞菌ABC转运蛋白编码基因PG 0683具有96%的同源性;HX 02与牙龈卟啉单胞菌PepO编码基因PG 0159具有97%的同源性;HX 03未找到类似同源性基因序列。结论:牙龈卟啉单胞菌在侵入KB细胞后发生了细菌毒力基因的表达变化,跨膜蛋白ABC转座子和PepO可能参与细菌侵入宿主细胞的致病过程。

关键词：牙龈卟啉单胞菌口腔上皮细胞侵入差异显示PCR

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硅藻土复合磁性壳聚糖对铬(Ⅵ)离子吸附性能

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精细化工 2018年第4期35卷 668-675页

作者：冯辉霞杨洋李全珍李东东张亚飞赵丹陈娜丽省部共建有色金属先进加工与再利用国家重点实验室甘肃兰州730050 兰州理工大学石油化工学院甘肃兰州730050

以硅藻土、壳聚糖和Fe3O4为主要原料,制得硅藻土复合磁性壳聚糖材料DE/M-CS。分别考察了Fe3O4和壳聚糖与硅藻土质量比、pH、吸附时间、吸附温度等对铬（Ⅵ）离子吸附性能的影响。结果表明,低温有利于吸附,当m（Fe3O4）∶m（壳聚糖）∶m... 详细信息

以硅藻土、壳聚糖和Fe3O4为主要原料,制得硅藻土复合磁性壳聚糖材料DE/M-CS。分别考察了Fe3O4和壳聚糖与硅藻土质量比、pH、吸附时间、吸附温度等对铬（Ⅵ）离子吸附性能的影响。结果表明,低温有利于吸附,当m（Fe3O4）∶m（壳聚糖）∶m（硅藻土）=1∶1∶1、溶液pH为3、温度为15℃、吸附时间为6 h、达到吸附平衡时,DE/M-CS对铬（Ⅵ）离子吸附量为47.8 mg/g;吸附符合Langmuir等温模型,符合准二级动力学模型,吸附为放热反应。在吸附材料吸附饱和后,可以采用0.1 mol/L氢氧化钠溶液进行再生利用,重复使用4次后,DE/M-CS对铬（Ⅵ）离子吸附量为37.8 mg/g。

关键词：硅藻土磁性壳聚糖吸附六价铬吸附模型水处理技术

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