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Rescue case of low birth weight infant with acute hepatic failure

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World Journal of Gastroenterology 2017年第40期23卷 7337-7342页

作者： Noriki Okada Yukihiro Sanada Taizen Urahashi Yoshiyuki Ihara Naoya Yamada yuta Hirata Takumi Katano Kentaro Ushijima Shinya Otomo Shujiro Fujita Koichi Mizuta Department of Transplant Surgery Jichi Medical University Department of Clinical Pharmacology Jichi Medical University Department of Pharmacy Jichi Medical University Department of Pediatrics Yokohama City University School of Medicine

We report a case involving a rescued low birth weight infant(LBWI) with acute liver failure. Case: The patient was 1594 g and 32^(3/7) gestational wk at birth. At the age of 11 d, she developed acute liver failure due to gestational alloimmune liver disease. Exchange transfusion and high-dose gamma globulin therapy were initiated, and body weight increased with enteral nutrition. Exchange transfusion was performed a total of 33 times prior to living donor liver transplantation(LDLT). Her liver dysfunction could not be treated by medications alone. At 55 d old and a body weight of 2946 g, she underwent LDLT using an S2 monosegment graft from her mother. Three years have passed with no reports of intellectual disability or liver dysfunction. LBWIs with acute liver failure may be rescued by LDLT after body weight has increased to over 2500 g.

关键词： Liver transplantation Acute liver failure Low birth weight infant Transplantable body weight Monosegment graft

Two cases of pancreatic ductal adenocarcinoma with intrapancreatic metastasis

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World Journal of Gastroenterology 2016年第41期22卷 9222-9228页

作者： Yusuke Fujita Minoru Kitago Yohei Masugi Osamu Itano Masahiro Shinoda yuta Abe Taizo Hibi Hiroshi Yagi Yoko Fujii-Nishimura Michiie Sakamoto Yuko Kitagawa Department of Surgery Keio University School of Medicine Department of Pathology Keio University School of Medicine

There are no standardized diagnostic criteria for intrapancreatic metastasis of pancreatic ductal adenocarcinoma(PDAC). Here, we report two cases of patients with PDAC who were pathologically diagnosed as harboring intrapancreatic metastasis. In both cases, the main lesions were located in the pancreatic body, and no other lesion was detected preoperatively. The patients were diagnosed with pancreatic body cancers and distal pancreatectomy was performed. Pathological findings revealed microscopic cancer nests, which had connections to neither the main lesion nor the premalignant lesion in the pancreatic tail parenchyma. In both cases, the histological type of the daughter lesion was quite similar to that of the main lesion. Hence, we diagnosed the daughter lesions as metastatic foci in the pancreas. Although intrapancreatic metastasis of PDAC has been regarded as a poor prognostic factor, few reports of intrapancreatic metastasis are available. This article reports two such cases and provides a review of the literature.

关键词：癌胰腺的 ductal 瘤 micrometastasis 复发 Carcinogenesis

How to maintain nutritional status after esophagectomy via the Tanaka method

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Journal of Cancer Metastasis and Treatment 2021年第1期7卷 785-793页

作者： Yoshihiro Tanaka yuta Sato Tomonari Suetsugu Junichi Mase Ritsuki Takaha Naoki Okumura Nobuhisa Matsuhashi Takao Takahashi Kazuhiro Yoshida Department of Surgical Oncology Graduate School of MedicineGifu UniversityGifu 501-1194Japan.

Aim:Many therapeutic means have emerged to treat esophageal *** relating to nutritional status such as body weight maintenance are important to the continuation of these *** this study,we investigated methods to extend the administration of diversified treatments for patients with esophageal cancer,especially regarding measures to suppress body weight loss after ***:We retrospectively evaluated a strategy for preventing postoperative body weight loss which can hinder the continuation of treatment via a reconstruction method aimed at safety and comfort combined with postoperative dietary intake and nutritional support for esophageal cancer ***:The subjects comprised 386 patients who underwent subtotal stomach reconstruction during esophageal cancer surgery performed from January 2008 to January 2021 at Gifu University *** anastomotic leakage rate was 0.5%.By administering oral nutritional supplementation under strict rules using ENSURE®H during the perioperative period,the percentage of body weight loss after 5 years could be limited to 4.78%compared to that before *** assessing early feeling of fullness measured using the EORTC QLQ-OES18 at postoperative months 3,12,24,36,48,and 60 were 1.7±0.3,2.0±0.2,1.2±0.3,1.3±0.2,1.5±0.2,and 1.4±0.1,***:Considering methods to eliminate the factors that prevent continuation of treatment may lead to sustainable treatment against esophageal *** surgical reconstruction and nutritional management will allow maintenance of body weight and good quality of life.

关键词： Esophageal cancer nutrition reconstruction oral nutritional supplementation

Comparison of clinical trial registry systems and registered trials between Japan and China

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Comparison of clinical trial registry systems and registered...

Augmented reality: The use of the PicoLinker smart glasses improves wire insertion under fluoroscopy

第三届中日双边药理学和临床药理学学术会议

作者： TSUTANI Kiichiro OISHI yuta Dept.of Drug Policy and Management Graduate School of Pharmaceutical SciencesUniversity of TokyoJapan Dept.of Drug Policy and Management Graduate School of Pharmaceutical SciencesUniversity of TokyoJapan

＜正＞AIM Awareness of clinical trial registry （CTR） has increased globally since the International Committee of Medical Journal Editors （ICMJE） adopted in 2004 a trials-registration *** also established the International Clinical Trial Registry Platform （ICTRP, http://***/ictrp/）.There are currently 4 CTRs in Asia,3 in Japan and 1 in *** study ex- amines the 4 systems in terms of organization,review process,characteristics of the trials registered,etc. METHODS Information was collected through Internet and *** Japan established UMIN- CTR（http://***/ctr）,the first CTR in an academic setting,in June *** is one of the five CTRs in the world recognized by ICMJE.626 trials （mostly pub- licly-funded） were registered in UMIN-CTR as of 30 April *** July 2005,JAPIC-CTI （http://***- ***） was established by industry-funded *** registry has 532 registered drug trials （mostly industry- funded）.In December 2005,JMA-CCT （https://dbcen- ***,***/ctrialr/） was established by Ja- pan Medical ***-CCT is unique because all 9 trials registered are publicly-funded trials to be used to support future NDAs.A web portal is planned to be set up to link all CTRs in *** April 2006,China estab- lished ChiCTR （http://***/）.Twenty-two trials were submitted for posting in this registry but only 12 trials were officially *** the 12 registered trials, all but one are *** trials are in the field of traditional Chinese medicine,including a comparative study of traditional Chinese and Western *** nine journals in China have adopted a trials-registration policy,but the level of awareness of this policy is still low.

关键词： clinical trial registry Japan China Comparison ICMJE ICTRP

来源： cnki会议评论

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World Journal of Orthopedics 2017年第12期8卷 891-894页

作者： Takafumi Hiranaka Takaaki Fujishiro Yuichi Hida Yosaku Shibata Masanori Tsubosaka yuta Nakanishi Kenjiro Okimura Harunobu Uemoto Department of Orthopaedic Surgery and Joint Surgery CenterTakatsuki General Hospital

AIM To demonstrate the feasibility of the wearable smart glasses, Pico Linker, in guide wire insertion under fluoroscopic guidance. METHODS Under a fluoroscope, a surgeon inserted 3 mm guide wires into plastic femurs from the lateral cortex to the femoral head center while the surgeon did or did not wear Pico Linker, which are wearable smart glasses where the fluoroscopic video was displayed(10 guide wires each). RESULTS The tip apex distance, radiation exposure time and total insertion time were significantly shorter while wearing the Pico Linker smart glasses. CONCLUSION This study indicated that the Pico Linker smart glasses can improve accuracy, reduce radiation exposure time, and reduce total insertion time. This is due to the fact that the Pico Linker smart glasses enable surgeons to keep their eyes on the operation field.

关键词： Smart glasses Imaging Wearable devices Fluoroscopy Guide wire insertion

Pediatric living donor liver transplantation for congenital hepatic fibrosis using a mother's graft with von Meyenburg complex: A case report

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World Journal of Gastroenterology 2016年第44期22卷 9865-9870页

作者： Naoya Yamada Yukihiro Sanada Takumi Katano Masahisa Tashiro yuta Hirata Noriki Okada Yoshiyuki Ihara Atsushi Miki Hideki Sasanuma Taizen Urahashi Yasunaru Sakuma Koichi Mizuta Department of Transplant Surgery Jichi Medical University Department of Surgery Jichi Medical University

This is the first report of living donor liver transplantation(LDLT) for congenital hepatic fibrosis(CHF) using a mother's graft with von Meyenburg complex. A 6-year-old girl with CHF, who suffered from recurrent gastrointestinal bleeding, was referred to our hospital for liver transplantation. Her 38-year-old mother was investigated as a living donor and multiple biliary hamartoma were seen on her computed tomography and magnetic resonance imaging scan. The mother's liver function tests were normal and she did not have any organ abnormality, including polycystic kidney disease. LDLT using the left lateral segment(LLS) graft from the donor was performed. The donor LLS graft weighed 250 g; the graft recipient weight ratio was 1.19%. The operation and post-operative course of the donor were uneventful and she was discharged on post-operative day(POD) 8. The graft liver function was good, and the recipient was discharged on POD 31. LDLT using a graft with von Meyenburg complex is safe and useful. Long-term follow-up is needed with respect to graft liver function and screening malignant tumors.

关键词： Congenital hepatic fibrosis Von Meyenburg complex Living donor liver transplantation Pediatric liver transplantation

Penile and scrotal strangulation by stainless steel rings in an human immunodeficiency virus positive man: A case report

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世界临床病例杂志 2023年第24期11卷 5811-5816页

作者： Daisuke Usuda Nobuyoshi Kaminishi Masashi Kato Yuto Sugawara Runa Shimizu Tomotari Inami Shiho Tsuge Riki Sakurai Kenji Kawai Shun Matsubara Risa Tanaka Makoto Suzuki Shintaro Shimozawa yuta Hotchi Ippei Osugi Risa Katou Sakurako Ito Kentaro Mishima Akihiko Kondo Keiko Mizuno Hiroki Takami Takayuki Komatsu Jiro Oba Tomohisa Nomura Manabu Sugita Emergency and Critical Care Medicine Juntendo University Nerima HospitalNerima 177-8521TokyoJapan Clinical Training Center Juntendo University Nerima HospitalNerima 177-8521TokyoJapan Sports Medicine Juntendo UniversityBunkyo 113-8421TokyoJapan

BACKGROUND Penoscrotal constriction devices are either used as autoerotic stimuli or to increase sexual pleasure or performance by maintaining an erection for a longer period,and a variety of metallic and non-metallic objects are *** the other hand,penile strangulation is a rare urologic emergency that requires prompt evaluation and intervention to prevent long-term *** goal of treating penile incarceration is to remove the foreign object as soon as *** the other hand,removal can be very challenging,and often requires resourcefulness and a multidisciplinary *** SUMMARY A 47-year-old man who has sex with men was transferred to our hospital for persistent phallodynia and scrotal pain,accompanying swelling due to strangulation by stainless steel *** medical history included acquired immunodeficiency *** day prior,he had put three stainless steel rings on his penis and scrotum before sexual *** sexual intercourse,he was unable to remove them,due to swelling of his penis and *** swelling persisted,and he felt pain in the affected area the next day,then he was transferred to our hospital by *** emergency department found that his penis and scrotum were markedly engorged and *** established a diagnosis of penile and scrotal strangulation by stainless steel *** unsuccessfully attempted to cut the rings using a cutter,then requested a rescue team via emergency medical *** cut through each ring in two places,using an electric-powered angle grinder,and successfully removed all of the ***,he was discharged and went *** We report the first case of penile and scrotal strangulation by stainless steel rings in an human immunodeficiency virus positive person.

关键词： Penile strangulation Stainless steel ring Human immunodeficiency virus Urologic emergency Management Case report

Secondary pulmonary infection by Fusarium solani and Aspergillus niger during systemic steroid treatment for COVID-19:A case report

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世界临床病例杂志 2023年第26期11卷 6280-6288页

作者： Daisuke Usuda Masashi Kato Yuto Sugawara Runa Shimizu Tomotari Inami Shiho Tsuge Riki Sakurai Kenji Kawai Shun Matsubara Risa Tanaka Makoto Suzuki Shintaro Shimozawa yuta Hotchi Ippei Osugi Risa Katou Sakurako Ito Kentaro Mishima Akihiko Kondo Keiko Mizuno Hiroki Takami Takayuki Komatsu Jiro Oba Tomohisa Nomura Manabu Sugita Department of Emergency and Critical Care Medicine Juntendo University Nerima HospitalNerima 177-8521TokyoJapan Department of Sports Medicine Juntendo UniversityBunkyo 113-8421TokyoJapan

BACKGROUND Coronavirus disease 2019(COVID-19)-associated invasive pulmonary aspergillosis presents a diagnostic challenge due to its non-specific clinical/imaging features,as well as the fact that the proposed clinically diagnostic algorithms do not necessarily apply to COVID-19 *** addition,Fusarium *** a rare cause of opportunistic life-threatening fungal *** Fusarium infection in an immunocompromised host is intractable,with a high likelihood of resulting *** our knowledge,this is the first case of secondary pulmonary infection by Fusarium solani(***)and Aspergillus niger(***)during systemic steroid treatment for *** SUMMARY A 62-year-old male was transported to our hospital by ambulance with a complaint of fever and *** established a diagnosis of pneumococcal pneumonia,complicated with COVID-19 and septic shock,together with acute renal *** was admitted to the intensive care unit,to be treated with piperacillin/tazobactam,vancomycin,and 6.6 mg per day of dexamethasone sodium phosphate,along with noradrenaline as a vasopressor,ventilator management,and continuous *** condition improved,and we finished the vasopressor on the fifth hospital *** administered dexamethasone for ten days,and finished the course of *** the eleventh day,patient respiratory deterioration was observed,and a computed tomography scan showed an exacerbation of bilateral ground-glass-opacity-like consolidation,together with newly appeared cavitary lesions in the *** changed antibiotics to meropenem plus *** addition,a fungal infection was considered as a possibility based on microscopic findings of sputum,and we began coadministration of ***,the pneumonia worsened,and the patient died on the seventeenth day of ***,*** and *** were identified from sputum collected on the twelfth *** was believed that he developed a cell-mediated immune defic

关键词： Fusarium solani Aspergillus niger Pulmonary infection Cell-mediated immune deficiency Coronavirus disease 2019 Case report

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日本留学生听力习得调查与教学方法研究

日本留学生听力习得调查与教学方法研究

作者： yuta AOYAMA（青山悠太）西北大学

学位级别：硕士

在学习汉语的四种技能中,说、读、写都是一种主动性的行为,听却完全相反,它是一种被动性行为,它会受到诸如语流、语速、轻重音、生词以及语言本身许多问题的影响。这些因素的影响不是完全靠听者本身能够解决的。通过对日本留学生和外国... 详细信息

在学习汉语的四种技能中,说、读、写都是一种主动性的行为,听却完全相反,它是一种被动性行为,它会受到诸如语流、语速、轻重音、生词以及语言本身许多问题的影响。这些因素的影响不是完全靠听者本身能够解决的。通过对日本留学生和外国留学生听力的调查,对日本留学生的汉语听力水平的提高上,在汉语听力教学中认真分析日本留学生学习汉语听力的规律,给出解决日本留学生的汉语听力教学的有效方法和途径,促使他们汉语听力水平和综合运用能力的全面提高。

关键词：听力日本留学生外国留学生问卷调查教学方法