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Surgical Experience of a Partial Atrioventricular Septal Defect in an Elderly Patient: A Case Report

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World Journal of Cardiovascular Surgery 2013年第2期3卷 31-33页

作者： Yukiharu Sugimura Masaaki Toyama Masanori katoh yuji kato Department of Cardiovascular Surgery Fuji Heavy Industries Health Insurance Society Ota Memorial Hospital Ota Japan Department of Cardiovascular Surgery Kameda Medical Center Chiba Japan

The following paper describes patch closure (bovine pericardial sheet) of an ostium primum atrial septal defect and mitral valve repair (sutured mitral valve cleft + autologous pericardial annuloplasty + Alfieri’s method) in a 50-year-old man. He had been perfectly well until he was brought to the emergency room because of acute heart failure. Chest radiography revealed right-side heart enlargement. Electrocardiography indicated atrial flutter. Echocardiography revealed a large ostium primum atrial septal defect and moderate mitral regurgitation. The pulmonary-to-systemic blood flow ratio was 3.24. First, cardiologists performed catheter ablation of the cavotricuspid isthmus for atrial flutter. We performed patch closure of an ostium primum atrial septal defect and mitral valve repair after the patient’s heart failure was under control. The patient was discharged 13 days postoperatively in a satisfactory condition without any critical complications.

关键词： Partial Atrioventricular Septal Defect Incomplete Endocardial Cushion Defect Mitral Regurgitation Elderly Patient Repair

Natural history of asymptomatic gallbladder stones in clinic without beds:A long-term prognosis over 10 years

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World Journal of Clinical Cases 2024年第1期12卷 42-50页

作者： yuji Sakai Toshio Tsuyuguchi Hiroshi Ohyama Junichiro Kumagai Takashi Kaiho Masayuki Ohtsuka Naoya kato Tadao Sakai Department of Gastroenterology Sakai ClinicKimistu 299-1162Japan Department of Gastroenterology Graduate School of MedicineChiba UniversityChiba 260-8677Japan Department of Gastroenterology Chiba Prefectural Sawara HospitalChiba Prefectural Sawara HospitalSawara 287-0003Japan Department of Gastroenterology Kimitsu Central HospitalKisarazu 292-8535Japan Department of Surgery Kimitsu Central HospitalKisarazu 292-8535Japan Department of General Surgery Graduate School of MedicineChiba UniversityChiba 260-8677Japan

BACKGROUND Several studies have explored the long-term prognosis of patients with asymp-tomatic gallbladder *** reports were primarily conducted in facilities equipped with beds for addressing symptomatic *** To report the long-term prognosis of patients with asymptomatic gallbladder stones in clinics without bed *** We investigated the prognoses of 237 patients diagnosed with asymptomatic gallbladder stones in clinics without beds between March 2010 and October *** symptoms developed,patients were transferred to hospitals where appropriate treatment was *** investigated the asymptomatic and survival periods during the *** Among the 237 patients,214(90.3%)remained asymptomatic,with a mean asymptomatic period of 3898.9279±46.871 d(50-4111 d,10.7 years on average).Biliary complications developed in 23 patients(9.7%),with a mean survival period of 4010.0285±31.2788 d(53-4112 d,10.9 years on average).No patient died of biliary *** The long-term prognosis of asymptomatic gallbladder stones in clinics without beds was *** the condition became symptomatic,the patients were transferred to hospitals with beds that could address it;thus,no deaths related to biliary complications were *** finding suggests that follow-up care in clinics without beds is possible.

关键词： Gallbladder stone Acute cholangitis Acute cholecystitis Asymptomatic gallbladder stone Symptomatic gallbladder stone

A Modified Branched Graft Inversion Technique Employing a Syringe Inserter in Ascending Aortic Replacement for Type A Aortic Dissection

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World Journal of Cardiovascular Surgery 2014年第7期4卷 95-100页

作者： Masashi Kawabori Takashi Murakami Kuntae Ahn yuji kato Mitsuhisa Kotani Masaaki Toyama Department of Cardiovascular Surgery Kameda General Hospital Chiba Japan

Purpose: To achieve good outcomes during aortic surgery with circulatory arrest, a secure and non-bleeding anastomosis must be achieved rapidly to ensure brain protection. We report our initial experiences with a modified Branched Graft Inverting (BGI) technique using an inserter under mild hypothermia. We aimed to reduce the surgical duration and to prevent unnecessary damage to the fragile aorta. Methods: We retrospectively reviewed patients with type A acute aortic dissection (AAD) who underwent distal anastomosis via the modified BGI technique using an inserter between January 2012 and March 2013. Open distal anastomosis was performed under mild hypothermia with right hemisphere perfusion from the right axillary artery. Results: Eight patients were enrolled. There was no mortality. Circulatory arrest time was reproducibly 20.3 ± 1.9 min, which was sufficient to complete non-bleeding distal anastomoses. The average rectal temperature during circulatory arrest was 26.5℃ ± 1.9℃. All patients were extubated the day after the operation without any neurological deficit. Conclusion: The modified BGI technique employing an inserter and mild hypothermia offered easy, secure, and reproducible distal anastomosis for ascending aortic replacement for type A acute aortic dissection. Our outcomes were favorable and support further development of this technique.

关键词： Aortic Dissection Ascending Replacement Syringe Branched Graft Inversion Mild Hypothermia

Current status of diagnosis and therapy for intraductal papillary neoplasm of the bile duct

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World Journal of Gastroenterology 2021年第15期27卷 1569-1577页

作者： yuji Sakai Masayuki Ohtsuka Harutoshi Sugiyama Rintaro Mikata Shin Yasui Izumi Ohno Yotaro Iino Jun kato Toshio Tsuyuguchi Naoya kato Department of Gastroenterology and Nephrology Graduate School of MedicineChiba UniversityChiba 260-8670Japan Department of General Surgery Graduate School of MedicineChiba UniversityChiba 260-8670Japan

Bile duct epithelial tumours showing papillary neoplasm in the bile duct lumen are present in the intrahepatic and extrahepatic bile *** images of these tumours are distinctive and diverse,including histological images with a low to high grade dysplasia,infiltrating and noninfiltrating characteristics,excessive mucus production,and similarity to intraductal papillary mucinous neoplasm(IPMN)of the *** World Health Organization Classification of Tumours of the Digestive System in 2010 named these features,intraductal papillary neoplasm of the bile duct(IPNB),as precancerous lesion of biliary *** is currently classified into type 1 that is similar to IPMN,and type 2 that is not similar to *** of IPNB spreads superficially,and diagnosis with cholangioscopy is considered mandatory to identify accurate localization and *** of IPNB is said to be better than normal bile duct cancer.

关键词： Intraductal papillary neoplasm of the bile duct Intraductal papillary mucinous neoplasm of the pancreas Peroral cholangioscopy Cholangioscopy

Short-and long-term results of endoscopic ultrasoundguided transmural drainage for pancreatic pseudocysts and walled-off necrosis

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World Journal of Gastroenterology 2017年第39期23卷 7110-7118页

作者： Yuto Watanabe Rintaro Mikata Shin Yasui Hiroshi Ohyama Harutoshi Sugiyama yuji Sakai Toshio Tsuyuguchi Naoya kato Department of Gastroenterology Graduate School of Medicine Chiba University

AIM To evaluate the short-and long-term results of endoscopic ultrasound-guided transmural drainage(EUS-GTD) for pancreatic fluid collection(PFC) and identify the predictive factors of treatment outcome for walled-off necrosis(WON) managed by EUS-GTD *** We investigated 103 consecutive patients with PFC who underwent EUS-GTD between September 1999 and August 2015. Patients were divided into four groups as follows: WON(n = 40), pancreatic pseudocyst(PPC; n = 11), chronic pseudocyst(n = 33), and others(n = 19). We evaluated the short-and long-term outcomes of the treatment. In cases of WON, multiple logistic regression analyses were performed to identify the predictor variables associated with the treatment success. In addition, PFC recurrence was examined in patients followed up for more than 6 mo and internal stent removal after successful EUS-GTD was *** In this study, the total technical success rate was 96.1%. The treatment success rate of WON, PPC, chronic pseudocyst, and others was 57.5%, 90.9%, 91.0%, and 89.5%, respectively. Contrast-enhanced computed tomography using the multivariate logistic regression analysis revealed that the treatment success rate of WON was significantly lower in patients with more than 50% pancreatic parenchymal necrosis(OR = 17.0; 95%CI: 1.9-150.7; P = 0.011) and in patients with more than 150 mm of PFC(OR = 27.9; 95%CI: 3.4-227.7; P = 0.002).The recurrence of PFC in the long term was 13.3%(median observation time, 38.8 mo). Mean amylase level in the cavity was significantly higher in the recurrence group than in the no recurrence group(P = 0.02).CONCLUSION The reduction of WON by EUS-GTD alone was associated with the proportion of necrotic tissue and extent of the cavity. The amylase level in the cavity may be a predictive factor for recurrence of PFC.

关键词： Endoscopic ultrasound-guided transmural drainage Pancreatic fluid collection Revised Atlanta Classification Walled-off necrosis

Coherent X-ray mirage: discovery and possible applications

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High Power Laser Science and Engineering 2014年第2期2卷 1-6页

作者： Tatiana Pikuz Anatoly Faenov Sergey Magnitskiy Nikolay Nagorskiy Momoko Tanaka Masahiko Ishino Masaharu Nishikino yuji Fukuda Masaki Kando Yoshiaki kato Tetsuya Kawachi Quantum Beam Science Directorate Japan Atomic Energy Agency Kizugawa Kyoto 619-0215 Japan Joint Institute for High Temperatures Russian Academy of Sciences Moscow 125412 Russia Institute for Academic Initiatives Osaka University International Laser Center of M.V. Lomonosov Moscow State University The Graduate School for the Creation of New Photonics Industries Hamamatsu Shizuoka 431-1202 Japan

In the far field of the intensity distribution of the beam delivered by a two-stage transient–collisional excitation X-ray laser(XRL), a non-expected interference pattern that is stable from shot to shot has been discovered. It is demonstrated that the interference is caused by the emergence of an imaginary source in the amplifying plasma, which is phase matched to the radiation of the generator. The observed phenomenon is called an X-ray coherent mirage. To explain the obtained results, a new theoretical approach is developed. The basic essential conditions for formation of the X-ray mirage are formulated, and possible applications are discussed. This paper details the experiments, including the formulation of the necessary and sufficient conditions for formation of the X-ray mirage, and possible applications are discussed.

关键词： coherent seeded beams mirage phase-matching X-ray lasers X-ray plasma optics

Live-cell single-molecule imaging of the cytokine receptor MPL for analysis of dynamic dimerization

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Journal of Molecular Cell Biology 2016年第6期8卷 553-555页

作者： Akihiko Sakamoto Takashi Tsukamoto yuji Furutani Yuki Sudo Kazuyuki Shimada Akihiro Tomita Hitoshi Kiyoi Takashi kato Takashi Funatsu Graduate School of Pharmaceutical Sciences The University of TokyoTokyo 1130033Japan Department of Haematology and Oncology Nagoya University Graduate School of MedicineNagoya 4668550Japan Graduate School of Medicine Dentistry and Pharmaceutical SciencesOkayama UniversityOkayama 7008530Japan Department of Life and Coordination-Complex Molecular Science Institute for Molecular ScienceOkazaki 4448585Japan Department of Structural Molecular Science SOKENDAIOkazaki 4448585Japan Core Research for Evolutional Science and Technology Japan Science and Technology AgencyTokyo 1020076Japan Institute for Advanced Research Nagoya UniversityNagoya 4648601Japan Department of Haematology Fujita Health University School of MedicineToyoake 4701192Japan Faculty of Education and Integrated Arts and Sciences Waseda UniversityTokyo 1628480Japan

Dear Editor,MPL is a cytokine receptor that regulates the production of myeloid cells,in particular megakaryocytes and platelets(Kaushansky,2005).Dimerization of MPL is important not only for the initiation of signalling(Kaushansky,2005)but also for the resistance to a recent therapy for myeloproliferative neoplasms(Koppikar et al.,2012).In the current model,cytokine receptors exist as a mixture of monomers and dimers without ligand stimulation,while ligand binding induces additional receptor dimerization(Kaushansky,2005).

关键词： dimer dynamic analysis

New method for long-term monitoring of intragastric pH

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World Journal of Gastroenterology 2007年第47期13卷 6410-6413页

作者： Shouko Ono Mototsugu kato yuji Ono Masahiro Asaka Division of Endoscopy Hokkaido University HospitalSapporo 060-8648Japan Department of Gastroenterology Hokkaido University Graduate School of MedicineSapporo 060-8648Japan

AIM: Consecutive monitoring of intragastric pH using the Bravo? capsule. METHODS: We put threads through a Bravo? capsule and then affixed it to the gastric wall by endoscopic hemoclipping in seven subjects. Study data were uploaded to a computer via Datalink every 48 h. In this way,repeated monitoring of intragastric pH was undertaken. RESULTS: All subjects were able to monitor gastric pH over a 1-wk period,and five for > 2 wk. No complications were encountered during the monitoring. After pH monitoring,we safely retrieved the capsule endoscopically. CONCLUSION: Clipping a Bravo? capsule onto the gastric wall enabled long-term intragastric pH monitoring. This is a methodological report of pH monitoring over a period of > 2 wk.

关键词： Gastric pH Ambulatory monitoring Bravo system

Gastrojejunostomy for pyloric stenosis after acute gastric dilatation due to overeating

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World Journal of Gastroenterology 2015年第5期21卷 1670-1674页

作者： Akiharu Kimura Norihiro Masuda Norihiro Haga Tomokazu Ito Kichirou Otsuka Jyunko Takita Hitoshi Satomura yuji Kumakura Hiroyuki kato Hiroyuki Kuwano Department of Surgery Utsunomiya National HospitalTochigi 329-1193Japan Department of General Surgical Science Gunma UniversityGraduate School of MedicineMaebashiGunma 371-8511Japan Department of Surgery I Dokkyo Medical UniversityTochigi 321-0293Japan

A 34-year-old woman presented at our hospital withabdominal distention due to *** gastric dilatation was *** patient was hospitalized,and nasogastric decompression was *** hospitalization day 3,she developed shock,and her respiratory state deteriorated,requiring intubation and mechanical *** decompression contributed to the improvement in her clinical *** was discharged 3 mo after *** outpatient follow-up,her dietary intake decreased,and her body weight gradually decreased by 14 *** upper gastrointestinal series and endoscopy revealed pyloric stenosis; therefore,we performed gastrojejunostomy 18 mo after her initial *** patient was discharged from the hospital with no postoperative *** necrosis and perforation due to overeating-induced gastric dilatation are life-threatening *** intervention may be required if delayed pyloric stenosis occurs after conservative *** report a case of pyloric stenosis due to overeating-induced gastric dilatation treated by gastrojejunostomy 18 mo after the initial presentation.

关键词： Acute gastric dilatation Bulimia Pyloric stenosis