Current status of diagnosis and therapy for intraductal papillary neoplasm of the bile duct

作     者：Yuji Sakai Masayuki Ohtsuka Harutoshi Sugiyama Rintaro Mikata Shin Yasui Izumi Ohno Yotaro Iino Jun Kato Toshio Tsuyuguchi Naoya Kato 

作者机构：Department of Gastroenterology and NephrologyGraduate School of MedicineChiba UniversityChiba 260-8670Japan Department of General SurgeryGraduate School of MedicineChiba UniversityChiba 260-8670Japan 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2021年第27卷第15期

页      面：1569-1577页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Intraductal papillary neoplasm of the bile duct Intraductal papillary mucinous neoplasm of the pancreas Peroral cholangioscopy Cholangioscopy 

摘      要：Bile duct epithelial tumours showing papillary neoplasm in the bile duct lumen are present in the intrahepatic and extrahepatic bile *** images of these tumours are distinctive and diverse,including histological images with a low to high grade dysplasia,infiltrating and noninfiltrating characteristics,excessive mucus production,and similarity to intraductal papillary mucinous neoplasm(IPMN)of the *** World Health Organization Classification of Tumours of the Digestive System in 2010 named these features,intraductal papillary neoplasm of the bile duct(IPNB),as precancerous lesion of biliary *** is currently classified into type 1 that is similar to IPMN,and type 2 that is not similar to *** of IPNB spreads superficially,and diagnosis with cholangioscopy is considered mandatory to identify accurate localization and *** of IPNB is said to be better than normal bile duct cancer.