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Primary ascending colon cancer accompanying skip metastases in left shoulder skin and left neck lymph node: A case report

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World Journal of Clinical Cases 2022年第23期10卷 8262-8270页

作者： jun-Chao Zhou Jian-jun Wang Tao Liu Qin Tong yue-jun Fang Zhang-Qiang Wu Qiang Hong Graduate School Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina Department of Surgical Oncology Jinhua Guangfu Oncology HospitalJinhua 321000Zhejiang ProvinceChina Department of General Surgery The Fourth Affiliated Hospital Zhejiang University School of MedicineJinhua 322000Zhejiang ProvinceChina

BACKGROUND Lymph node skip metastases are common in lung,breast,and thyroid cancer patients,but are rare in colon cancer ***,lymph node skip metastases occur in 1%-3%of colon cancer *** reports have demonstrated colon cancer skip metastases involving the retropancreatic and portocaval lymph nodes and Virchow's node;however,reports involving skip metastases into the left neck lymph nodes and left shoulder skin are extremely rare,as are related reports of clinical treatment and *** SUMMARY A 44-year-old Chinese man was admitted to the hospital for evaluation of persistent shoulder pain for 3 d and a cutaneous mass(3.0 cm×2.0 cm)on the left *** left shoulder cutaneous mass was excised and bisected,revealing tissues with a fish-like *** pathologic diagnosis of the cutaneous mass suggested a signature[CDX-2(++),CK20(++),Ki-67(+)>50%]of infiltrating or metastatic colorectal *** enhanced computed tomography scan of the abdomen revealed chronic appendicitis with fecal stone formation,cecal edema,and a pelvic effusion.A colonoscopy revealed a cauliflower-like mass within the ascending colon area that involved the *** surface of the ascending colon mass was eroded and bleeding;a biopsy was *** pathologic diagnosis of the colonoscopy biopsy was an ascending colon mucinous *** patient underwent a laparoscopic radical resection of the right colon based on the pathological *** tumor was 5.0 cm×4.5 cm×1.8 cm in size and infiltrated the entire thickness of the intestinal wall with vascular tumor *** nerve tissue involvement was *** ileum and colon resection margins were *** postoperative pathologic analysis revealed non-metastatic involvement of ileocecal,pericolic,or peri-ileal lymph *** postoperative medical examination revealed palpably enlarged lymph nodes in the left neck,and the following color Doppler ultrasound examination of the

关键词： Colon cancer Skip metastasis Skin metastasis Unknown primary tumor Case report

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移动荷载作用下建筑垃圾再生路面响应分析

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公路 2024年第1期69卷 58-65页

作者：杨振宇杨三强褚嘉怡候月军刘杰河北大学建筑工程学院保定市071000 北京市政建设集团有限责任公司北京市100000 保定市绿生环境科技有限公司保定市071000

为研究砖混类建筑垃圾用于道路基层填筑的再生路面在移动荷载下的力学响应问题,通过室内试验对不同再生骨料掺量的再生混合料进行抗压回弹模量试验,分析再生混合料力学性能特点;利用ABAQUS有限元分析软件建立再生路面三维道路模型,分析... 详细信息

为研究砖混类建筑垃圾用于道路基层填筑的再生路面在移动荷载下的力学响应问题,通过室内试验对不同再生骨料掺量的再生混合料进行抗压回弹模量试验,分析再生混合料力学性能特点;利用ABAQUS有限元分析软件建立再生路面三维道路模型,分析了移动荷载下再生路面力学响应规律;并基于正交试验,就再生下基层厚度、底基层厚度及再生骨料掺量对结构力学响应影响进行敏感性分析。研究结果表明:(1)建筑垃圾再生骨料具有压碎值大、密度小、吸水率大的特点,再生混合料最佳含水率与最大干密度随再生料掺量的增多分别增大与减小,再生混合料抗压回弹模量随再生料掺量的增多呈现先增大后减小的趋势,因此将砖混类再生骨料用于基层铺筑时建议掺量在40%以下,并应严格控制再生骨料中砖混比例;(2)在移动荷载作用下,建筑垃圾再生路面动力响应具有“应变集中”与“应变交替”的现象,最大竖向应变达到381.94με;(3)建筑垃圾再生路面下基层厚度、底基层厚度对道路性能的影响大于再生骨料掺量的影响。研究结果可为建筑垃圾再生路面结构设计提供理论依据和技术参考。

关键词：道路工程路面基层建筑垃圾移动荷载力学响应正交试验

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On Modeling Drilling Load in Lunar Regolith Simulant

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Chinese Journal of Mechanical Engineering 2018年第1期31卷 41-52页

作者： Qi-Quan Quan Chong-Bin Chen Zong-Quan Deng jun-yue Tang De-Wei Tang State Key Laboratory of Robotics and System Harbin Institute of Technology

Drilling and coring, as effective ways to obtain lunar regolith along the longitudinal direction, are widely applied in the lunar sampling field. Conventionally, modeling of drill-soil interaction was divided into soil cutting and screw conveyance processes, ignoring the differences in soil mechanical properties between them. To improve the modeling accuracy, a hypothesis that divides the drill-soil interaction into four parts: cuttings screw conveyance, cuttings extruding, cuttings bulldozing, and in situ simulant cutting, is proposed to establish a novel model based on the passive earth pressure theory. An iterative numerical calculation method is developed to predict the drilling loads. A drilling and coring testbed is developed to conduct experimental tests. Drilling experiments indicate that the drilling loads calculated by the proposed model match well the experimental results. The proposed research provides the instructions to adopt a suitable drilling strategy to match the rotary and penetrating motions, to increase the safety and reliability of drilling control in lunar sampling missions.

关键词： Lunar regolith drilling Lunar regolith simulant Drill-simulant interaction Screw conveyance

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Analytical Model for the Palaeoenvironmental Evolution of the Nihewan Beds

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Acta Geologica Sinica(English Edition) 1991年第1期65卷 77-86页

作者： yue jun Wen Qizhong Tianjin Institute of Geology and Mineral Resources Institute of Geochemistry, Academia Sinica Tianjin Institute of Geology and Mineral Resources China

In this paper, the evolutional characteristics of palaeoclimate and oxidation-reduction conditions as well asacidity-alkalinity environment are discussed by means of the step-regression, cluster, optimal partitioning andcorrelation analyses of CaCO_3, C / P_2O_5, Fe^(2+) / Fe^(3+), pH and Eh values, taking the Xiaodukou section in theNihewan basin as an example. The CaCO_3, C / P_2O_5 and pH were calculated respectively using the optimalpartitioning method. Thus five cold zones and six warm zones as well as five reduction and six oxidation zoneswere distinguished. Then the inductive method was used to produce four numerical groups: 8.10, 8.3-8.4,8.6-8.7 and 8.9-8,97. The above-mentioned results are respectively based on CaCO_3 content, C/P_2O_5 andpH values. From Fig. 3, Tables 1 and 2 it can be seen that the Nihewan Beds were formed mainly under a re-duction and slightly alkaline environment of cold climate, with pH values of 8.3-8.4. Fig. 3 shows that bed 35is approximately near the boundary between the Brunhes and Matuyama polarity epochs, 0.73 Ma in age; bed26 is roughly near the Jaramillo event (base), 0.97 Ma in age; bed 18 coincides roughly with themagnetostratigraphic boundary of 2.00 Ma (?). Bed 13 may be the Pleistocene-Pliocene boundary, 2.48 Ma inage. Thus geochemical zones Ⅰ, Ⅱ, Ⅲ and Ⅳ include respectively cold zones 1; 2 and 3; 4; and 5.

关键词： Analytical Model for the Palaeoenvironmental Evolution of the Nihewan Beds

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A new hybrid method with data‑characteristic‑driven analysis for artificial intelligence and robotics index return forecasting

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Financial Innovation 2023年第1期9卷 2019-2041页

作者： yue‑jun Zhang Han Zhang Rangan Gupta Business School Hunan UniversityChangsha 410082China Center for Resource and Environmental Management Hunan UniversityChangsha 410082China Department of Economics University of PretoriaPrivate Bag X20Hatfield 0028South Africa

Forecasting returns for the Artificial Intelligence and Robotics Index is of great significance for financial market stability,and the development of the artificial intelligence *** provide investors with a more reliable reference in terms of artificial intelligence index investment,this paper selects the NASDAQ CTA Artificial Intelligence and Robotics(AIRO)Index as the research target,and proposes innovative hybrid methods to forecast returns by considering its multiple structural ***,this paper uses the ensemble empirical mode decomposition(EEMD)method and the modified iterative cumulative sum of squares(ICSS)algorithm to decompose the index returns and identify the structural ***,it combines the least-square support vector machine approach with the particle swarm optimization method(PSO-LSSVM)and the generalized autoregressive conditional heteroskedasticity(GARCH)type models to construct innovative hybrid forecasting *** the one hand,the empirical results indicate that the AIRO index returns have complex structural characteristics,and present time-varying and nonlinear characteristics with high complexity and mutability;on the other hand,the newly proposed hybrid forecasting method(i.e.,the EEMD-PSO-LSSVM-ICSS-GARCH models)which considers these complex structural characteristics,can yield the optimal forecasting performance for the AIRO index returns.

关键词： Artificial Intelligence and Robotics index return forecasting PSO-LSSVM model GARCH model Decomposition and integration model Combination model

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Synthesis and Characterization of pH-Responsive Block Copolymers with Primary Amine Groups

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Chemical Research in Chinese Universities 2013年第2期29卷 389-395页

作者： WANG Hong ZHU yue-jun REN Xiao-na ZHANG Hong TAN Ye-bang Key Laboratory of Special Functional Aggregated Materials Ministry of Education School of Chemistry and Chemical Engineering Shandong University Jinan 250100 P. R. China State Key Laboratory of Offshore Oil Exploitation Technology Research Department of Research Center China National Offshore Oil Corporation Beijing 100027 P R. China

A new pH-responsive block copolymer, methoxy poly（ethylene glycol）-b-poly[5-methacrylamido- pentylamine hydrochloride]（mPEG-b-PMAAPA） was synthesized and characterized in this paper. The monomer 5-methacrylamido-pentylamine hydrochloride（MAAPA） and the macroinitiator（mPEG-ACVA） were synthesized, re- spectively, and mPEG-b-PMAAPA was then obtained by free radical polymerization. The structure and molecular weight of mPEG-b-PMAAPA were cont]rmed by hydrogen nuclear magnetic resonance（~H NMR） spectroscopy and gel permeation chromatography with multiangle laser light scattering（GPC-MALLS） measurements. At a low pH, it is hydrophilic due to the protonation of the primary amine groups. With increasing pH value, deprotonation occurs and the hydrophobicity of PMAAPA block increases. This molecular feature leads to interesting aggregation behavior of mPEG-b-PMAAPA in aqueous solutions at different pH values as revealed by dynamic light scattering（DLS） measurements, transmission electron microscopy（TEM） observations and resonance light scattering（RLS） measure- ments.

关键词： Block copolymer Polyamine pH-Responsive Water soluble copolymer

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A simple and convenient method for the synthesis of S-aryl phosphorothioates catalyzed by cesium hydroxide

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Chinese Chemical Letters 2013年第12期24卷 1103-1105页

作者： yue-jun Ouyang Yuan-Yuan Li Ning-Bo Li Xin-Hua Xu Department of Chemistry and Chemical Engineering Huaihua University College of Chemistry and Chemical Engineering Hunan University

In the presence of a catalytic amount of cesium hydroxide, the corresponding S-aryl phosphorothioates can he obtained by the reactions of dialkyl phosphites with diaryldisulfides in excellent yields at room temperature, using DMSO as a solvent. The reaction mechanism was discussed. The method provides a new and expedient path for the preparation of $-aryl phosphorothioates.

关键词： Cesium hydroxide Diaryldisulfides O O-Dialkyl-S-arylphosphorothioates

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Effects of Rattling Behavior of K and Cd Atoms along Different Directions in Anisotropic KCdAs on Lattice Thermal Transport and Thermoelectric Properties

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Energy & Environmental Materials 2024年第6期7卷 388-398页

作者： yue Wang Yinchang Zhao jun Ni Zhenhong Dai Department of Physics Yantai UniversityYantai 264005China State Key Laboratory of Low-Dimensional Quantum Physics Department of PhysicsTsinghua UniversityBeijing 100084China

We employ advanced first principles methodology,merging self-consistent phonon theory and the Boltzmann transport equation,to comprehensively explore the thermal transport and thermoelectric properties of ***,the study accounts for the impact of quartic anharmonicity on phonon group velocities in the pursuit of lattice thermal conductivity and investigates 3ph and 4ph scattering processes on phonon *** various methodologies,including examining atomic vibrational modes and analyzing 3ph and 4ph scattering processes,the article unveils microphysical mechanisms contributing to the lowκL within *** features include significant anisotropy in Cd atoms,pronounced anharmonicity in K atoms,and relative vibrations in non-equivalent As atomic *** atoms,situated between As layers,exhibit rattling modes and strong lattice anharmonicity,contributing to the observed lowκ*** flat bands near the valence band maximum translate into high PF,aligning with ultralowκL for exceptional thermoelectric *** optimal temperature and carrier concentration doping,outstanding ZT values are achieved:4.25(a(b)-axis,p-type,3×10^(19)cm^(−3),500 K),0.90(c-axis,p-type,5×10^(20)cm^(−3),700 K),1.61(a(b)-axis,n-type,2×10^(18)cm^(−3),700 K),and 3.06(c-axis,n-type,9×10^(17)cm^(−3),700 K).

关键词： anharmonic lattice dynamics electron transport characteristics first principles calculation lattice thermal transport octahedron thermoelectric properties

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硒砂瓜根系不同生态位细菌群落多样性及结构分析

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南方农业学报 2024年第4期55卷 985-995页

作者：朱滕滕岳思君谢志鹏王国琴郑蕊苏建宇宁夏大学生命科学学院/宁夏大学西部特色生物资源保护与利用教育部重点实验室宁夏银川750021

【目的】分析硒砂瓜根系不同生态位细菌群落结构及多样性,为了解硒砂瓜根系微生物组成规律,挖掘微生物资源,维持硒砂瓜根系土壤健康及微生物生态系统稳定提供理论参考。【方法】采用五点取样法采集根围、根际、根表和根内4个生态位土壤... 详细信息

【目的】分析硒砂瓜根系不同生态位细菌群落结构及多样性,为了解硒砂瓜根系微生物组成规律,挖掘微生物资源,维持硒砂瓜根系土壤健康及微生物生态系统稳定提供理论参考。【方法】采用五点取样法采集根围、根际、根表和根内4个生态位土壤样品,分别标记为SRW、SRJ、SRB和SRN,通过使用Illumina Miseq测序平台对硒砂瓜根系不同生态位细菌群落进行解析,探究硒砂瓜细菌群落Alpha多样性指数,包括Sobs、Shannon、Simpson、Chao1和ACE指数,比较各生态位及内生菌与硒砂瓜根系其他生态位在门和属分类水平上的细菌物种差异,并进行主坐标分析(PCoA)及溯源分析。【结果】土壤中(SRW、SRJ及SRB)细菌群落Sobs、Shannon、ACE和Chao1指数均显著高于内生菌群落(SRN)(PSRW>SRB>SRN,丰富度即ACE和Chao1指数排序为SRW>SRJ>SRB>SRN。硒砂瓜根系不同生态位细菌类群的优势门均为变形菌门(Proteobacteria)和放线菌门(Actinobacteriota),各生态位变形菌门占比59.59%~84.62%,4个生态位的优势属均为根瘤菌属(AllorhizobiumNeorhizobium-Pararhizobium-Rhizobium)、克雷伯氏菌属(Klebsiella)和固氮菌属(Azotobacter),根瘤菌属占比5.48%~15.68%。PCoA结果显示,硒砂瓜根系不同生态位的群落结构存在显著差异(R2=0.6651,P=0.001)。根系各生态位相对丰度前15的物种中,10个细菌门和8个细菌属的相对丰度存在显著差异。内生菌与硒砂瓜根系其他生态位相对丰度前15的物种中,8个细菌门和5个细菌属的相对丰度存在显著差异。溯源分析结果发现根际细菌群落中有55.70%来源于根围细菌,根表细菌群落中有65.75%来源于根际细菌,根内细菌群落中有90.75%来源于根表细菌,表明硒砂瓜根系不同生态位细菌群落来源之间存在一定相关性。【结论】宁夏硒砂瓜根系不同生态位细菌群落组成丰富,相对丰度有差异且细菌群落来源具有一定相关性,不同生态位对细菌群落具有选择及过滤作用。

关键词：硒砂瓜根系细菌群落生态位多样性群落结构

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新生儿重症监护病房医院感染与病原菌谱:一项单中心五年研究

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中国感染控制杂志 2024年第2期23卷 195-200页

作者：李艳敏张瑞敏平莉莉翟丽娜张晓丽韩军月河北北方学院研究生学院河北张家口075000 邯郸市中心医院新生儿科河北邯郸056000

目的了解新生儿重症监护病房(NICU)医院感染病原菌谱及变迁情况。方法收集2018年1月—2022年12月某院NICU发生医院感染新生儿的临床病历资料,回顾性分析医院感染的病原菌谱情况。结果共调查7 597例住院新生儿,240例发生医院感染,共26... 详细信息

目的了解新生儿重症监护病房(NICU)医院感染病原菌谱及变迁情况。方法收集2018年1月—2022年12月某院NICU发生医院感染新生儿的临床病历资料,回顾性分析医院感染的病原菌谱情况。结果共调查7 597例住院新生儿,240例发生医院感染,共263例次,医院感染发病率为3.16%,例次发病率为3.46%。其中血流感染96例(36.50%),呼吸系统感染70例(26.62%),感染部位不明确者57例(21.67%)。送检标本中共检出病原菌170株,其中革兰阳性菌78株(45.88%),以葡萄球菌属占比最高;革兰阴性菌78株(45.88%),以肺炎克雷伯菌为主;真菌14株(8.24%)。2018—2022年革兰阴性菌检出比率呈上升趋势(P<0.01)。结论 NICU医院感染以血流感染居多。近几年革兰阴性菌检出率逐年上升,临床应加强医院感染的预防与控制。

关键词：新生儿新生儿重症监护病房医院感染病原菌

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