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Transcutaneous electrical acupoint stimulation benefits postoperative pain relief of oocyte retrieval:A randomized controlled trial

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Journal of Integrative Medicine 2024年第1期22卷 32-38页

作者： Li-ying Liu yang Su rong-rong Wang yuan-yuan Lai lei Huang yi-ting Li Xin-yue Tao Meng-hua Su Xiao-yan Zheng Shi-chen Huang Yong-na Wu si-yi yu Fan-rong Liang Jie yang Acupuncture and Tuina School Chengdu University of Traditional Chinese MedicineChengdu 610000Sichuan ProvinceChina Traditional Chinese Medicine Department Sichuan Jinxin Xi’nan Women's and Children's HospitalChengdu 610000Sichuan ProvinceChina

Background Transvaginal oocyte retrieval is frequently followed by adverse events related to anesthesia and the *** research showed that transcutaneous electrical acupoint stimulation(TEAS)can relieve intraoperative pain and postoperative *** This study examined whether TEAS can alleviate pain and relieve adverse symptoms after oocyte ***,setting,participants and interventions Altogether 128 patients were randomly divided into the TEAS group and the mock TEAS *** two groups received a 30-minute-long TEAS or mock TEAS treatment that began 30 min after oocyte *** outcome measures The primary outcome was the visual analog scale(VAS)pain *** outcomes were pressure pain threshold,McGill score,pain rating index(PRI),present pain intensity(PPI),VAS stress score,VAS anxiety score,and postoperative adverse *** The baseline characteristics of the two groups were comparable(P>0.05).The VAS pain scores of the TEAS group were lower than those of the mock TEAS group at 60 and 90 min after oocyte retrieval(Psignificantly lower than those in the control group at 60 min after oocyte retrieval(P0.05).The TEAS group was superior to the mock TEAS group for relieving postoperative adverse symptoms(Psion TEAS treatment can relieve postoperative pain and postoperative adverse symptoms for patients undergoing oocyte retrieval.

关键词： Transcutaneous electrical acupoint stimulation Fertilization Embryo transfer Oocyte retrieval Pain Randomized controlled trial

Effect of Low-temperature Imidization on Properties and Aggregation Structures of Polyimide Films with Different Rigidity

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Chinese Journal of Polymer Science 2024年第8期42卷 1134-1146页

作者： yan jia lei Zhai Song Mo yi Liu Li-Xin Liu Xin-yu Du Min-Hui He Lin Fan Key Laboratory of Science and Technology on High-tech Polymer Materials Institute of ChemistryChinese Academy of SciencesBeijing 100190China School of Chemical Sciences University of Chinese Academy of SciencesBeijing 100049China

The traditional high-temperature preparation process of polyimide can cause many problems and limits the wider application in extreme *** important challenge to be solved urgently is the reduction of imidization *** this work,twelve kinds of polyimide films with different chain rigidity were prepared at low temperature of 200℃,in the absence or presence of imidazole used as the *** molecular rigidity and free volume were theoretically calculated,and relationship between structure and properties were systematically *** results show that imidization reaction under low temperatures is significantly affected by the rigidity of molecula r *** rigid structure of polyimide is not conducive to the low-temperature imidization,but this adverse effect can be eliminated by adding catalyst,resulting the notably increased imidization *** optical and thermal properties can be improved to a certain extent for the chemically catalyzed system,resulting in relatively higher heat resistance and thermal *** the mechanical performance could be determined by com plicating factors,greatly different from polyimide films prepa red by high temperature *** investigate aggregation structures of film s,the effect of chain rigidity and catalyst on the stacking or orientation of molecular chains was further *** wo rk can contribute to the understanding of chemically catalyzed imidization that is rarely reported in the existing research,and will provide guidance for the low-temperature preparation of high-performance polyimides.

关键词： Polyimide Imidization Catalyst Structure and properties Aggregation structures

Immediate Effect of Electro-acupuncture on Endometrial Blood Flow in Patients with Recurrent Implantation Failure:A Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第4期30卷 291-298页

作者： LAI yuan-yuan LIU Li-ying WU Yong-na HUANG lei ZHENG Xiao-yan GAN Di yu si-yi ZHONG ying LIANG Fan-rong ZHOU ying yanG Jie Acupuncture and Tuina School Chengdu University of Traditional Chinese MedicineChengdu(610032)China sichuan Jinxin Xi'nan Women's and Children's Hospital Chengdu(610032)China yuan TCM Wellness Pte.Ltd.(999002) Pulse TCM SingaporeSingapore

Objective To investigate the immediate effects of electro-acupuncture(EA)on endometrial blood flow among recurrent implantation failure(RIF)*** Eighty RIF patients,enrolled from March 2022 to December 2022,were randomly allocated into either the EA group(40 cases)or the waiting-list(WL)group(40 cases)by using a random number *** EA group underwent acupuncture at points of Shenting(GV 24),Baihui(GV 4),Benshen(GB 13),bilateral Zigong(EX-CA 1),Huangshu(KI 16),Sanyinjiao(SP 6)and Xuehai(SP10),and electric acupuncture apparatus was connected to EX-CA 1,KI 16,SP 6,and SP 10 with disperse-dense waves at 4/20 Hz frequencies for 30 min after transvaginal ultrasound,while the WL group received no *** primary outcome measured was the endometrial volume blood *** secondary outcomes included the bilateral uterine artery index,endometrial volume,endometrial blood flow type,vascular distribution index(VI^(MV))for endometrial and ovary,clinical pregnancy rate,and embryo implantation *** In the EA group,there was a notable decrease in the bilateral pulsatility index and a significant improvement in the endometrial blood flow type post-EA(Psignificant disparities were observed in vascular index,flow index,vascular blood flow index,uterine arterial blood flow indices,endometrial volume,clinical pregnancy rate and embryo implantation rate between the two groups after treatment(P>0.05).Besides,no adverse events related to EA were *** EA can promptly ameliorate VI^(MV) for the endometrial and right ovary,and endometrial blood flow *** randomized controlled trials are warranted to investigate the long-term effects of EA on blood flow of RIF patients and its implications for pregnancy outcomes.(Trial registration ***2200057377

关键词： electro-acupuncture recurrent implantation failure transvaginal ultrasound endometrial receptivityanalysis randomized controlledtrial

Hepatic arterial infusion chemotherapy with anti-angiogenesis agents and immune checkpoint inhibitors for unresectable hepatocellular carcinoma and meta-analysis

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World Journal of Gastroenterology 2024年第4期30卷 318-331页

作者： yu-Zhe Cao guang-lei Zheng Tian-Qi Zhang Hong-yan Shao jia-yu Pan Zi-Lin Huang Meng-Xuan Zuo Department of Minimally Invasive Interventional Therapy Sun Yat-sen University Cancer CenterGuangzhou 510060Guangdong ProvinceChina Department of Minimally Invasive Interventional Therapy State Key Laboratory of Oncology in South ChinaGuangzhou 510060Guangdong ProvinceChina Department of Minimally Invasive Interventional Therapy Guangdong Provincial Clinical Research Center for CancerGuangzhou 510060Guangdong ProvinceChina

BACKGROUND Hepatic arterial infusion chemotherapy(HAIC)has been proven to be an ideal choice for treating unresectable hepatocellular carcinoma(uHCC).HAIC-based treatment showed great potential for treating ***,large-scale studies on HAIC-based treatments and meta-analyses of first-line treatments for uHCC are *** To investigate better first-line treatment options for uHCC and to assess the safety and efficacy of HAIC combined with angiogenesis inhibitors,programmed cell death of protein 1(PD-1)and its ligand(PD-L1)blockers(triple therapy)under real-world *** Several electronic databases were searched to identify eligible randomized controlled trials for this ***-level pooled analyses of hazard ratios(HRs)and odds ratios(ORs)were *** was a retrospective single-center study involving 442 patients with uHCC who received triple therapy or angiogenesis inhibitors plus PD-1/PD-L1 blockades(AIPB)at Sun Yat-sen University Cancer Center from January 2018 to April *** score matching(PSM)was performed to balance the bias between the *** Kaplan-Meier method and cox regression were used to analyse the survival data,and the log-rank test was used to compare the suvival time between the *** A total of 13 randomized controlled trials were *** alone and in combination with sorafenib were found to be effective treatments(P values for ORs:HAIC,0.95;for HRs:HAIC+sorafenib,0.04).After PSM,176 HCC patients were included in the *** triple therapy group(n=88)had a longer median overall survival than the AIPB group(n=88)(31.6 months vs 14.6 months,PsiON This meta-analysis suggests that HAIC-based treatments are likely to be the best choice for *** findings confirm that triple therapy is more effective for uHCC patients than AIPB.

关键词： Unresectable hepatocellular carcinoma Hepatic arterial infusion chemotherapy Angiogenesis inhibitors Programmed cell death protein 1 Programmed death ligand 1

Layered oxide cathodes for sodium-ion batteries:microstructure design,local chemistry and structural unit

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Science China Chemistry 2024年第1期67卷 191-213页

作者： Ling-yi Kong Han-Xiao Liu yan-Fang Zhu jia-yang Li yu Su Hong-Wei Li Hai-yan Hu yi-Feng Liu Ming-Jing yang Zhuang-Chun jian Xin-Bei jia Shu-lei Chou Yao Xiao Institute for Carbon Neutralization College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325035China

Because of the low price and abundant reserves of sodium compared with lithium,the research of sodium-ion batteries(siBs)in the field of large-scale energy storage has returned to the research *** oxides distinguish themselves from the mains cathode materials of siBs owing to their advantages such as high specific capacity,simple synthesis route,and environmental ***,the commercial development of the layered oxides is limited by sluggish kinetics,complex phase transition and poor air *** on the research ideas from macro-to micro-scale,this review systematically summarizes the current optimization strategies of sodium-ion layered oxide cathodes(SLOC)from different dimensions:microstructure design,local chemistry regulation and structural unit *** the dimension of microstructure design,the various structures such as the microspheres,nanoplates,nanowires and exposed active facets are prepared to improve the slow kinetics and electrochemical ***,from the view of local chemistry regulation by chemical element substitution,the intrinsic electron/ion properties of SLOC have been enhanced to strengthen the structural ***,the optimization idea of endeavors to regulate the physical and chemical properties of cathode materials essentially is put forward from the dimension of structural unit *** opinions and strategies proposed in this review will provide some inspirations for the design of new SLOC in the future.

关键词： sodium-ion batteries layered oxide cathodes microstructure design local chemistry structural unit

Experimental and numerical investigations on acoustic damping of monoclinic crystalline wideband sound absorbing structures

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Journal of Central South University 2024年第6期31卷 1931-1944页

作者： XIE Su-chao HE lei yan Hong-yu ZHANG Feng-yi HE Guan-di WANG jia-cheng Key Laboratory of Traffic Safety on Track Ministry of EducationSchool of Traffic&Transportation EngineeringCentral South UniversityChangsha 410075China Joint International Research Laboratory of Key Technology for Rail Traffic Safety Changsha 410075China National&Local Joint Engineering Research Center of Safety Technology for Rail Vehicle Changsha 410075China

In order to overcome the limitations of traditional microperforated plate with narrow sound absorption bandwidth and a single structure,two multi-cavity composite sound-absorbing materials were designed based on the shape of monoclinic crystals:uniaxial oblique structure(UOS)and biaxial oblique structure(BOS).Through finite element simulation and experimental research,the theoretical models of UOS and BOS were verified,and their sound absorption mechanisms were *** the same time,the influence of multi-cavity composites on sound absorption performance was analyzed based on the theoretical model,and the influence of structural parameters on sound absorption performance was *** research results show that,in the range of 100-2000 Hz,UOS has three sound absorption peaks and BOS has five sound absorption *** frequency range of the half-absorption bandwidth(α>0.5)of UOS and BOS increases by 242% and 229%,*** with traditional microperforated sound-absorbing structures,the series and parallel hybrid methods significantly increase the sound-absorbing bandwidth of the sound-absorbing *** research has guiding significance for noise control and has broad application prospects in the fields of transportation,construction,and mechanical design.

关键词： monoclinic crystal microperforated plate acoustic metamaterials inclined cavity sound absorption

Megafossils of Betulaceae from the Oligocene of Qaidam Basin and their paleoenvironmental and phytogeographic implications

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Plant Diversity 2024年第1期46卷 101-115页

作者： Tao yang jia-Hao Cai yan-Zhi Dai Hong-yu Chen lei Han Li Zhang Wei-yu Liang Xu-Jun Li Wen-jia Li Jing-yu Wu San-Ping Xie De-Fei yan School of Earth Sciences and Key Laboratory of Mineral Resources in Western China(Gansu Province) Lanzhou UniversityLanzhou 730000China Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesBeijing 100044China State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and Palaeontology and Center for Excellence in Life and PaleoenvironmentChinese Academy of SciencesNanjing 210008China Center for Research and Education on Biological Evolution and Environments School of Earth Sciences and EngineeringNanjing UniversityNanjing 210023China

Understanding the paleoenvironment and phytogeographical history of the Tibetan Plateau,China relies on discovering new plant *** Qaidam Basin has long been regarded as an ideal‘field laboratory’to investigate the paleoclimate and paleobiological evolution of the northern Tibetan ***,fossil angiosperms from the Qaidam Basin are rare,and our knowledge of its paleovegetation is ***,we report fossil leaves and fruits of Betulaceae found from the Oligocene Shangganchaigou Formation of northwestern Qaidam Basin(Huatugou area).Comparative morphological analysis led us to assign the fruits to the Betula subgenus Betula and the leaves to Carpinus *** findings,together with other reported fossil plants from the same locality,reveal a close floristic linkage between the Qaidam Basin and Europe during the *** northern pathway of this floristic exchange may have crossed through the Qaidam Basin during the late *** floristic linkage may have been facilitated by the continuous narrowing of the Turgai Strait and stronger westerlies,which transported moisture and provided favorable climatic ***,fossil plants collected from the Qaidam Basin suggest that during the Oligocene this region had warm and humid deciduous broad-leaf forest,which differs from the region’s modern vegetation and indicates that the Qaidam Basin may have been a suitable region for these plants to flourish and spread during the Oligocene.

关键词： Paleoenvironment Biogeography Betulaceous fossil Qaidam basin Tibetan Plateau Oligocene

single-cell profiling of the pig cecum at various developmental stages

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Zoological Research 2024年第1期45卷 55-68页

作者： yan-yuan Xiao Qing Zhang Fei Huang Lin Rao Tian-Xiong Yao si-yu yang lei Xie Xiao-Xiao Zou Li-Ping Cai jia-Wen yang Bin yang Lu-Sheng Huang National Key Laboratory for Swine Genetic Improvement and Germplasm Innovation Ministry of Science and Technology of ChinaJiangxi Agricultural UniversityNanchangJiangxi 330045China

The gastrointestinal tract is essential for food digestion,nutrient absorption,waste elimination,and microbial ***-cell transcriptome profiling of the intestinal tract has greatly enriched our understanding of cellular diversity,functional heterogeneity,and their importance in intestinal tract development and *** such profiling has been extensively conducted in humans and mice,the single-cell gene expression landscape of the pig cecum remains ***,single-cell RNA sequencing was performed on 45572 cells obtained from seven cecal samples in pigs at four different developmental stages(days(D)30,42,150,and 730).Analysis revealed 12 major cell types and 38 subtypes,as well as their distinctive genes,transcription factors,and regulons,many of which were conserved in *** increase in the relative proportions of CD8^(+)T and Granzyme A(low expression)natural killer T cells(GZMA^(low)NKT)cells and a decrease in the relative proportions of epithelial stem cells,Tregs,RHEX^(+)T cells,and plasmacytoid dendritic cells(pDCs)were noted across the developmental ***,the post-weaning period exhibited an up-regulation in mitochondrial genes,COX2 and ND2,as well as genes involved in immune activation in multiple cell ***-cell crosstalk analysis indicated that IBP6^(+)fibroblasts were the main signal senders at D30,whereas IBP6^(−)fibroblasts assumed this role at the other *** cells established interactions with epithelial cells and IBP6^(+)fibroblasts in the D730 cecum through mediation of GZMA-F2RL1/F2RL2 *** study provides valuable insights into cellular heterogeneity and function in the pig cecum at different development stages.

关键词： single-cell RNA-seq Cecum Bama Xiang pigs Various developmental stages Cellular heterogeneity

Review of Baduanjin and resistance exercise for the mental health of patients with hematologic malignancies

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World Journal of Psychiatry 2024年第8期14卷 1165-1173页

作者： Ya-Zhou Shen Feng Chen jia-Wen yu yan Zhang Ling-Xiang Lu Yong-Li Huo si-Ting Chu Bing Cao lei-Wen Tang Department of Nursing Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Nursing The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina

Patients with hematological tumors experience physical and psychological stress,and negative psychological ***,an emerging psychological rehabil-itation method combined with resistance exercise,has received widespread *** study reviews the current status of the application of Baduanjin combined with resistance exercise in improving the negative psychological state of patients with hematological tumors and discusses its problems and *** a literature review and comprehensive analysis,the application of Baduanjin and resistance exercise in the psychological rehabilitation of patients with hematological tumors was identified and *** results showed that Baduanjin with resistance exercise had a positive effect on improving negative psychological states of patients with hematological tumors,which can alleviate anxiety,depression,and other adverse emotions,and improve quality of ***,there is a lack of unified and standardized exercise intervention programs for practical application,and patient participation and compliance must be *** combined with resistance exercise can potentially improve the negative psychological status of patients with hematological tumors;however,it is still necessary to further standardize and improve the exercise program improving patient participation and *** studies should strengthen theoretical exploration and empirical research,providing more effective psychological rehabilitation strategies for patients with hematological tumors.

关键词： Hematological tumors Baduanjin Resistance exercise Negative psychological state Psychological rehabilitation