检索结果-南通市图书馆

Ring-opening Polymerization ofε-Caprolactone Using Lanthanide Tris(4-tert-butylphenolate)s as a Single-component Initiator

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2003年第10期14卷 1021-1023页

作者： Cui ping yu, Li fang ZHANG, Zhi Quan SHEN Institute of Polymer Science, Zhejiang University, Hangzhou 310027 Institute of Polymer Science Zhejiang University Hangzhou 310027 China

The ring-opening polymerization of e-caprolactone (CL) initiated by novel single lanthanide tris(4-tert-butylphenolate)s [Ln(OTBP)3] is reported. Single-component La(OTBP)3 can effectively prepare polycaprolactone (PCL) with over 90% yield and viscosity average molecular weight about 60 x 10 under quite mild conditions: molar ratio of CL to initiator is 1000, 60 C, 2 h in toluene. Mechanism study indicates that the monomer inserts into the growing chain via the break of acyl-oxygen bond of CL.

关键词： Lanthanide tris(4-tert-butylphenolate)s e-caprolactone ring-opening polymerization.

Emerging mechanisms and implications of c GAS-STING signaling in cancer immunotherapy strategies

在线全文

学校读者我要写书评

暂无评论

Cancer Biology & Medicine 2024年第1期21卷 45-64页

作者： Jiawen Zhang Sihui yu Qiao Peng ping Wang Lan fang Tongji University Cancer Center Shanghai Tenth People’s HospitalSchool of MedicineTongji UniversityShanghai 200072China Reproductive Medicine Center Department of Obstetrics and GynecologyShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 201620China Department of Obstetrics and Gynecology Zhongshan HospitalFudan UniversityShanghai 200032China

The intricate interplay between the human immune system and cancer development underscores the central role of immunotherapy in cancer *** this landscape,the innate immune system,a critical sentinel protecting against tumor incursion,is a key *** cyclic GMP-AMP synthase(c GAS)and stimulator of interferon genes(STING)pathway has been found to be a linchpin of innate immunity:activation of this signaling pathway orchestrates the production of type I interferon(IFN-α/β),thus fostering the maturation,differentiation,and mobilization of immune effectors in the tumor ***,STING activation facilitates the release and presentation of tumor antigens,and therefore is an attractive target for cancer *** strategies to activate the STING pathway,including use of pharmacological agonists,have made substantial advancements,particularly when combined with immune checkpoint *** approaches have shown promise in preclinical and clinical settings,by enhancing patient survival *** review describes the evolving understanding of the c GAS-STING pathway's involvement in tumor biology and ***,this review explores classical and non-classical STING agonists,providing insights into their mechanisms of action and potential for optimizing immunotherapy *** challenges and complexities,the c GAS-STING pathway,a promising avenue for enhancing cancer treatment efficacy,has the potential to revolutionize patient outcomes.

关键词： cGAS-STING pathway type I interferon cyclic dinucleotide STING agonist cancer immunotherapy

Helmholtz decomposition with a scalar Poisson equation in elastic anisotropic media

在线全文

学校读者我要写书评

暂无评论

Petroleum Science 2024年第3期21卷 1597-1610页

作者： Xin-yu fang Gang Yao Qing-Qing Zheng ping-Min Zhang Di Wu Feng-Lin Niu State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China Unconventional Petroleum Research Institute China University of Petroleum(Beijing)Beijing102249China Department of Mathematics College of ScienceChina University of Petroleum(Beijing)Beijing102249China College of Geophysics China University of Petroleum(Beijing)Beijing102249China Department of Earth Environmental and Planetary SciencesRice UniversityHoustonTX77005UA

P-and S-wave separation plays an important role in elastic reverse-time *** can reduce the artifacts caused by crosstalk between different modes and improve image *** addition,P-and Swave separation can also be used to better understand and distinguish wave types in complex *** present,the methods for separating wave modes in anisotropic media mainly include spatial nonstationary filtering,low-rank approximation,and vector Poisson *** of these methods require multiple Fourier transforms or the calculation of large matrices,which require high computational costs for problems with large *** this paper,an efficient method is proposed to separate the wave mode for anisotropic media by using a scalar anisotropic Poisson operator in the spatial *** 2D problems,the computational complexity required by this method is 1/2 of the methods based on solving a vector Poisson ***,compared with existing methods based on pseudoHelmholtz decomposition operators,this method can significantly reduce the computational *** examples also show that the P and S waves decomposed by this method not only have the correct amplitude and phase relative to the input wavefield but also can reduce the computational complexity significantly.

关键词： Anisotropic media Scalar anisotropic Poisson equation Improved elastic wavefield decomposition

Control of Virtual Synchronous Generator for Frequency Regulation Using a Coordinated Self-adaptive Method

在线全文

学校读者我要写书评

暂无评论

CSEE Journal of Power and Energy Systems 2024年第1期10卷 175-184页

作者： Hongwei fang Zhiwei yu School of Electrical and Information Engineering and Key Laboratory of Tianjin Electric Power System Simulation and Control Tianjin UniversityTianjin 300072China

Power inverter adopting virtual synchronous generator(VSG)control can provide inertia support for distributed generation ***,it cannot take into account the dynamic regulation characteristics of ***,when the system encounters a sudden change in load or disturbance,the dynamic process of frequency regulation will be greatly *** view of this issue,an improved VSG control strategy based on a coordinated self-adaptive(CSA)method is *** time domain analysis method is used to study the influences of virtual inertia and damping parameter perturbation on the system steady and dynamic ***,in order to make the control strategy suitable for large load changes and suppress frequency variations beyond the limit,the secondary frequency modulation is introduced into the control *** the coordinated adaptive control of virtual inertia,virtual damping and frequency modulation,the dynamic performance of vSG frequency regulation can be obviously *** and experiment results have verified the effectiveness of the proposed CSA control strategy.

关键词： Coordinated self-adaptive method frequency regulation time domain analysis virtual synchronous generator

Automatic analysis of textual garden path phenomenon： A computational perspective

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

通讯和计算机（中英文版） 2008年第10期5卷 58-65页

作者： yu ping-fang DU Jia-li Chinese-Based Center for Dictionary Research Directly under the National Education Ministry Yantai 264025 China School of Foreign Languages Ludong University Yantai 264025 China

This paper puts forward a text-circled semantic schema by which a special flow chart of cognitive alteration and processing breakdown in Machine Translation (MT) system is clearly presented. Based on the theoretical analysis of textual Garden Path Phenomenon (GPP), we devise a formula to measure the dramatically changeable value of textual GPP. The data-provided evidence in A Farewell to Arms shows the textual GPP can motivate the development of plots and adjust the analyst s original horizon of expectation. Despite the limitation of incompatible, subjective and sample-restricted features involved in the theoretical framework and formula, this computational analysis makes MT system pay more attention to text-circled cognitive alteration rather than only highlight the lexical or syntactic translation, and as a result aims to make the effectiveness of machine translation of the literary text improved.

关键词：自动化技术计算方法分析角度花园路径现象语言学

Cognitive deviation originating from the different systems between English and Chinese

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sino-US English Teaching 2008年第8期5卷 40-44,53页

作者： DU Jia-li yu ping-fang School of Foreign Languages Ludong University Yantai 264025 China 2. Chinese-Based Center for Dictionary Research Directly under the National Education Ministry Yantai 264025 China

This article discusses the result of cognitive deviation originating from the lexical and syntactic difference between English and Chinese. By analyzing three different aspects involved in this paper, namely, synthetic versus analytic, compact versus diffusive and hypotactic versus paratactic deviations, a conclusion can be drawn that consciousness of necessary information qualifies a translator for work only when he is familiar with this kind of cognitive deviation.

关键词： cognition deviation comparison contrast bilingual education

Poly(3-hexylthio) thiophene Field-effect Transistor Device Performance: Impact of the Content of Hexylthio Side Chain on Backbone

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第1期42卷 14-23,I0005页

作者： Hao-yu Liu Lian-He Han Ling-Wei Kong Li-ping Zhu Xiao-Lan Qiao Mei-fang Zhu State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringDonghua UniversityShanghai 201620China School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

Regioregular poly(3-hexylthio)thiopene(P3HTT) has emerged tremendous potential in organic electronic applications due to the strong noncovalent interactions from the sulfur atom linked to thiophene. However, P3HTT generally exhibits low charge mobility mostly due to poor solution processability attributed to dense arrangement of hexylthio side chain in polymer, which led to strong noncovalent interactions among sulfur atoms. To balance the nonvalent interaction and aggregation for P3HTT, herein, we systematically study the effect of hexylthio side chain content in polymer backbone on the structure and properties. A series of regioregular P3HTT-based homopolymers(P3HTT, P3HTT-50,P3HTT-33 and P3HTT-25) were prepared via Kumada catalyst transfer polycondensation method from a set of mono-, bi-, ter-and quarterthiophenes containing different contents of hexylthio side chain. The DFT calculation shows the planarity of polymers backbone could be improved through reducing the density of hexylthio side chain in polymer mainchain. And significant changes in their crystallinity, aggregation and optical properties were observed with the content of hexylthio side chain reducing. The P3HTT-33 displayed the highest field-effect transistor hole mobility of 2.83×10^(-2) cm^(2)·V^(-1)·s^(-1) resulting from a balance between the crystallinity and planarity. This study demonstrates modulating the content of hexylthio side chain in P3HTT is an effective strategy to optimize the opto-electronic properties of polymer obtaining excellent semiconductor device performance.

关键词： Conjugated polymer Polythiophene Noncovalent interaction Molecular aggregation Organic field-effect transistor

Trudinger–Moser Inequalities on a Closed Riemann Surface with a Symmetric Conical Metric

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2024年第9期40卷 2263-2284页

作者： yu fang yun Yan YANG College of Teacher Education Quzhou UniversityQuzhou 324003P.R.China Department of Mathematics Renmin University of ChinaBeijing 100872P.R.China

This is a continuation of our previous work(*** ***.,20,1295–1324,2020).Let(Σ,g)be a closed Riemann surface,where the metric g has conical singularities at finite *** G is a group whose elements are isometries acting on(Σ,g).Trudinger–Moser inequalities involving G are established via the method of blow-up analysis,and the corresponding extremals are also *** extends previous results of Chen(***.,1990),Iula–Manicini(Nonlinear Anal.,2017),and the authors(2020).

关键词： Trudinger-Moser inequality blow-up analysis conical singularity

Chronic administration of triclosan leads to liver fibrosis through hepcidin-ferroportin axis-mediated iron overload

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第3期137卷 144-154页

作者： Jing Liu Lecong Zhang fang Xu ping Zhang Yang Song College of Eco-Environmental Engineering Guizhou Minzu UniversityGuiyang 550025China The Institute of Karst Wetland Ecology Guizhou Minzu UniversityGuiyang 550025China State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China

Triclosan(TCS)has been manufactured as an antibacterial compound for half a ***,it is widely used in various personal care products;however,its potential adverse effects raise a lot of ***,we create a long-term oral administration mouse model and identify the corresponding hepatotoxicity of *** discover that daily intragastric administration of 10 mg/kg TCS to mice for 12 weeks results in severe hepatic *** study displays that hepatic iron increased 18%,23%and 29%upon oral TCS treatment for4,8 and 12 weeks,*** by hepatic iron variation,splenic and duodenal iron are increased,which indicates systemic iron *** only excessive iron accumulated in the liver,abnormal hepatic malondialdehyde,prostaglandin synthase 2 and glutathione peroxidase 4 are pointed to *** study uncovers that hepcidin expression increases 7%,10%,4%in serum and 2.4-,4.8-,and 2.3-fold on transcriptional levels upon TCS exposure for 4,8 and 12 weeks,*** together,the mice in the TCS-treated group show disordered systemic iron homeostasis via the upregulated hepatic hepcidin-ferroportin ***,both hepatic iron overload(systemic level)and hepatocyte ferroptosis(cellular level)are accused of TCS-induced liver ***■,an iron scavenger,significantly ameliorates TCS-induced liver *** summary,this study confirms the impact of TCS on liver fibrosis;a critical signal pathway is also *** significance of the current study is to prompt us to reevaluate the“pros and cons”of TCS applications.

关键词： Triclosan Iron metabolism Hepcidin Hepatotoxicity Liver fibrosis