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Optimization of phenol degradation by Candida tropicalis Z-04 using Plackett-Burman design and response surface methodology

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Journal of Environmental Sciences 2011年第1期23卷 22-30页

作者： Jiangya Zhou Xiaojuan yu Cong Ding Zhiping Wang Qianqian Zhou Hao pao Weimin Ca School of Environmental Science and Engineering Shanghai Jiaotong University Dongchuan Road 800 Shanghai 200240 China.

Statistical experimental designs were used to optimize the process of phenol degradation by Candida tropicalis Z-04, isolated from phenol-degrading aerobic granules. The most important factors influencing phenol degradation （p 〈 0.05）, as identified by a two-level Plackett-Burman design with 11 variables, were yeast extract, phenol, inoculum size, and temperature. Steepest ascent method was undertaken to determine the optimal regions of these four significant factors. Central composite design （CCD） and response surface analysis were adopted to further investigate the mutual interactions between these variables and to identify their optimal values that would generate maximum phenol degradation. The analysis results indicated that interactions between yeast extract and temperature, phenol and temperature, inocuhim size and temperature affected the response variable （phenol degradation） significantly. The predicted results showed that the maximum removal efficiency of phenol （99.10%） could be obtained under the optimum conditions of yeast extract 0.41 g/L, phenol 1.03 g/L, inoculum size 1.43% （V/V） and temperature 30.04℃. These predicted values were further verified by validation experiments. The excellent correlation between predicted and experimental values confirmed the validity and practicability of this statistical optimum strategy. This study indicated the excellent ability of C. tropicalis Z-04 in degrading high-strength phenol. Optimal conditions obtained in this experiment laid a solid foundation for further use of this microorganism in the treatment of highstrength phenol effluents.

关键词： phenol degradation Candida tropicalis Z-04 optimization Plackett-Burman design response surface methodology

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Multiple bowel intussusceptions from metastatic localized malignant pleural mesothelioma:A case report

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World Journal of Gastroenterology 2010年第31期16卷 3984-3986页

作者： Hsien Liu yu-Jen Cheng Hsin-pao Chen Jau-Chung Hwang Po-Chih Chang Division of General Surgery Department of Sur-geryE-DA Hospital/I-Shou University Division of Thoracic Surgery Department of SurgeryE-DA Hospital/I-Shou University Division of Colon and Rectal Surgery Depart-ment of SurgeryE-DA Hospital/I-Shou University Department of Pathology E-DA Hospital/I-Shou University

Localized malignant pleural mesothelioma (LMPM) is a rare occurrence, and gastrointestinal intra-luminal metastases have not previously been reported. Herein, we report a patient with LMPM who presented with a local recurrence 10 mo after initial en bloc surgical resection. Abdominal computed tomography was performed for intractable, vague abdominal pain with episodic vomiting, which showed a "target sign" over the left lower quadrant. Laparotomy revealed several intra-luminal metastatic tumors in the small intestine and colon and a segmental resection of metastatic lesions was performed. Unfortunately, the patient died of sepsis despite successful surgical intervention. Though local recurrence is more frequent in LMPM, the possibility of distant metastasis should not be ignored in patients with non-specifi c abdominal pain.

关键词： Localized malignant pleural mesothelioma Intussusception Distant metastasis

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“勿以恶小而为之”:《申报》所见晚清社会欺诈问题研究

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社会科学战线 2024年第9期 164-175页

作者：李玉南京大学中华民国史研究中心江苏南京210023

在“变局”时代的晚清社会,各类欺诈现象愈演愈烈,其危害大者包括“掉包”“放白鸽”“人口拐卖”“冒充官员”等十余种,依侵权性质可分为“物的欺诈”“人的欺诈”与“信誉的欺诈”三大类。行骗成风与近代中国社会结构的剧变有很大关系... 详细信息

在“变局”时代的晚清社会,各类欺诈现象愈演愈烈,其危害大者包括“掉包”“放白鸽”“人口拐卖”“冒充官员”等十余种,依侵权性质可分为“物的欺诈”“人的欺诈”与“信誉的欺诈”三大类。行骗成风与近代中国社会结构的剧变有很大关系,是这一时期中国“城市病”的表现之一,也印证了晚清社会治理的不良与困境。以《申报》为视域,既有利于还原各类骗局的细节与内情,也可深化对于晚清欺诈现象社会面影响的认识。各类欺诈行为频发增大了城市社会的“公共危险”性,减损了民众对于城市的信任,增加了社会生产与生活的成本,阻滞了城市公共空间建设。用“公共信用的‘漏桶’”或可形象地说明社会欺诈之于城市近代化发展的不良影响。

关键词：晚清社会欺诈现象 “城市病” 《申报》

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Mapping and genetic validation of a grain size QTL qGS7.1 in rice(Oryza sativa L.)

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Journal of Integrative Agriculture 2019年第8期18卷 1838-1850页

作者： XUE pao ZHANG Ying-xin LOU Xiang-yang ZHU Ai-ke CHEN yu-yu SUN Bin yu Ping CHENG Shi-hua CAO Li-yong ZHAN Xiao-deng Zhejiang Key Laboratory of Super Rice Research/State Key Laboratory of Rice Biology/China National Rice Research Institute Hangzhou 310006 P.R.China Nanchong Academy of Agricultural Sciences Nanchong 637000 P.R. China National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural University Wuhan 430070 P.R.China Institute of Crop Breeding and Cultivation Shanghai Academy of Agricultural Sciences Shanghai 201403 P.R.China

Grain size is a major determinant of grain weight, which is one of the components of rice yield. The objective o this study was to identify novel, and important quantitative trait loci(QTLs) for grain size and weight in rice. QTLs were mapped using a BC4F4 population including 192 backcross inbred lines(BILs) derived from a backcross between Xiaolijing(XLJ) and recombinant inbred lines(RILs). The mapping population was planted in both Lingshui(Hainan, 2015) and Fuyang(Zhejiang, 2016), with the short-and long-day conditions, respectively. A total of 10 QTLs for grain length, four for grain width, four for the ratio of grain length to width, and 11 for grain weight were detected in at least one environment and were distributed across 11 chromosomes. The phenotypic variance explained ranged from 6.76–25.68%, 14.30–34.03%, 5.28–26.50%, and 3.01–22.87% for grain length, grain width, the ratio of grain length to width, and thousand grain weight, respectively. Using the sequential residual heterozygotes(SeqRHs) method, qGS7.1, a QTL for grain size and weight, was mapped in a 3.2-Mb interval on chromosome 7. No QTLs about grain size and weight were reported in previous studies in this region, providing a good candidate for functional analysis and breeding utilization.

关键词： rice (Oryza sativa L.) quantitative trait loci grain size grain weight residual heterozygote

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Extracorporeal shock wave therapy in treating ischial non-union following Bernese periacetabular osteotomy:A case report

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World Journal of Orthopedics 2024年第10期15卷 991-996页

作者： Jun Yan Jun-yu Zhu Fei-Fei Zhao Jian Xiao Hao Li Ming-Xin Wang Jing Guo Liang Cui Geng-Yan Xing Department of Orthopedics The Third Medical Center of Chinese People's Liberation Army General HospitalBeijing 100039China Department of Orthopaedic Anhui Medical UniversityHefei 230032Anhui ProvinceChina Department of Orthopedics The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011Hebei ProvinceChina Department of Orthopedics The Fourth Medical Center of Chinese People’s Liberation Army General HospitalBeijing 100039China Department of Orthopaedic The Third Medical Center of Chinese People’s Liberation Army General HospitalThe Armed Police Clinical CollegeAnhui Medical UniversityHefei 230022Anhui ProvinceChina

BACKGROUND Extracorporeal shock wave therapy(ESWT)is increasingly being recognized as an advantageous alternative for treating non-union due to its efficacy and minimal associated ***-union following Bernese periacetabular osteotomy(pao)is particularly challenging,with a reported 55%delayed union and 8%***,we highlight a unique case of ischial non-union post-pao treated successfully with a structured ESWT *** SUMMARY A 50-year-old patient,diagnosed with left ischial non-union following the pao,underwent six cycles of ESWT treatment across ten *** cycle,spaced four weeks apart,consisted of five consecutive ESWT sessions without *** X-ray follow-ups showed progressive disappearance of the fracture line and fracture *** patient ultimately achieved a satisfactory asymptomatic recovery and bone *** The results from this case suggest that this ESWT regimen can be a promising non-invasive treatment strategy for non-union following pao.

关键词： Ischial non-union Extracorporeal shock wave therapy Non-union Bernese periacetabular osteotomy Case report

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Atomically isolated Pd sites within Pd-S nanocrystals enable trifunctional catalysis for direct,electrocatalytic and photocatalytic syntheses of H_(2)O_(2)

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Nano Research 2022年第3期15卷 1861-1867页

作者： Tang Yang Chengyong Yang Jiabo Le Zhiyong yu Lingzheng Bu Leigang Li Shuxing Bai Qi Shao Zhiwei Hu Chih-Wen pao Jun Cheng Yonggang Feng Xiaoqing Huang State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China College of Chemistry Chemical Engineering and Materials ScienceSoochow UniversitySuzhou 215123China Max-Planck-Institute for Chemical Physics of Solids Nöthnitzer Street 40Dresden 01187Germany “National Synchrotron Radiation Research Center” Hsinchu 30076TaiwanChina

Although high-efficiency production of hydrogen peroxide(H_(2)O_(2))can be realized separately by means of direct,electrochemical,and photocatalytic synthesis,developing versatile catalysts is particularly challenging yet ***,for the first time we reported that palladium-sulphur nanocrystals(Pd-S NCs)can be adopted as robust and universal catalysts,which can realize the efficient O_(2) conversion by three *** a result,Pd-S NCs exhibit an excellent selectivity(89.5%)to H_(2)O_(2)with high productivity(133.6 mol·kgcat^(−1)·h^(−1))in the direct synthesis,along with the significantly enhanced H_(2)O_(2)production activity and stability via electrocatalytic and photocatalytic *** is demonstrated that the isolated Pd sites can enhance the adsorption of O_(2) and inhibit its O–O bond dissociation,improving H_(2)O_(2)selectivity and reducing H_(2)O_(2)*** study confirms that the difference in surface atom composition and arrangement is the key factor for different ORR mechanisms on Pd NCs and Pd-S NCs.

关键词： Pd-S universality direct synthesis of H_(2)O_(2) oxygen reduction photocatalysis

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Predictors of unfavorable outcome at 90 days in basilar artery occlusion patients

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World Journal of Clinical Cases 2022年第12期10卷 3677-3685页

作者： yu-Chen Chiu Jia-Li Yang Wei-Chun Wang Hung-yu Huang Wei-Liang Chen pao-Sheng Yen Ying-Lin Tseng Hsiu-Hsueh Chen Sheng-Ta Tsai Department of Neurology An Nan HospitalChina Medical UniversityTainan 709204Taiwan College of Medicine China Medical UniversityTaichung 404332Taiwan Department of Anesthesiology China Medical University HospitalTaichung 404332Taiwan Department of Neurology China Medical University HospitalTaichung 404332Taiwan Department of Radiology China Medical University HospitalTaichung 404332Taiwan Department of Radiology Kuang Tien General HospitalTaichung 404332Taiwan Stroke Center China Medical University HospitalTaichung 404332Taiwan

BACKGROUND In a previous study,basilar artery occlusion(BAO)was shown to lead to death or disability in 80%of the *** treatment for BAO patients in the acute stage includes thrombolysis and intra-arterial thrombectomy,but not all patients benefit from these ***,understanding the predictors of outcome before initiating these treatments is of special *** To determine the predictors related to the 90-d clinical outcome in patients with BAO in an Asian *** We performed a retrospective case review of patients admitted to a tertiary stroke center between 2015 and *** used the international classification of diseases-10 criteria to identify cases of posterior circulation stroke.A neurologist reviewed every case,and patients fulfilling the criteria defined in the Basilar Artery International Cooperation Study were *** then analyzed the patients’characteristics and factors related to the 90-d *** We identified a total of 99 patients as real BAO *** these patients,33(33.3%)had a favorable outcome at 90 d(modified Rankin Scale:0–3).Moreover,72 patients received intra-arterial thrombectomy,while 13 patients received intravenous tissue-type plasminogen activator *** observed a favorable outcome in 33.3%of the cases and an unfavorable outcome in 66.7%of the *** found that the initial National Institutes of Health Stroke Scale(NIHSS)score and several BAO symptoms,including impaired consciousness,tetraparesis,and pupillary abnormalities,were significantly associated with an unfavorable outcome(P<0.05),while cerebellar symptoms were associated with a favorable outcome(P<0.05).In the receiver operating characteristic(ROC)analysis,the areas under the ROC curve of initial NIHSS score,impaired consciousness,tetraparesis,cerebellar symptoms,and pupillary abnormalities were 0.836,0.644,0.727,0.614,and 0.614,*** NIHSS score showed a higher AUROC(0.836)compared to BAO ***

关键词： Basilar artery occlusion National Institutes of Health Stroke Scale Natural course Outcome Asian

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Massive left atrial and interatrial septal calcification after mitral valve replacement

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Chinese Medical Journal 2008年第15期121卷 1497-1499页

作者： yu-Shen Lin Feng-Chun Tsai pao-Hsien Chu The First Cardiovascular Division Department of Internal Medicine Chang Gung Memorial Hospital Taipei Taiwan China Division of Thoracic & Cardiovascular Surgery Chang Gung Memorial Hospital Chang Gung University College of Medicine Taipei Taiwan China

Massive calcification of left atrium is an uncommon complication of long-standing rheumatic valvular disease, and is most often observed in patients with a previous operation on mitral valve. Most patients have experienced symptoms for more than 15 years. Massive calcification of the left atrium generality spared the interatrial septum in the previous studies. However, to our knowledge, fewer than five cases have presented as full left atrial calcification （Table）.

关键词： calcification left atrial interatrial septal mitral valve replacement

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基于时序模型的火工品贮存可靠性分析方法

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兵工学报 2009年第12期30卷 1679-1683页

作者：洪东跑赵宇北京航空航天大学工程系统工程系北京100191

火工品具有寿命长且可靠性高的特点,为了提高其贮存可靠性分析的精确性,研究了火工品及其贮存可靠性的特点,利用感度试验数据,给出了基于时序模型的火工品贮存可靠性分析方法。该方法利用升降法试验数据给出了感度分布参数的极大似然估... 详细信息

火工品具有寿命长且可靠性高的特点,为了提高其贮存可靠性分析的精确性,研究了火工品及其贮存可靠性的特点,利用感度试验数据,给出了基于时序模型的火工品贮存可靠性分析方法。该方法利用升降法试验数据给出了感度分布参数的极大似然估计,并结合先验信息给出了刻度参数的收缩估计。数值模拟结果表明,在一定条件下,收缩估计具有更优的统计性质。采用时序模型来描述感度分布参数随贮存时间的变化趋势;结合分布参数的估计值给出了模型参数的最小二乘估计;然后利用该模型对分布参数进行外推。结合信仰推断方法,给出了火工品贮存可靠度置信下限。数值算例表明该方法合理、可行,可用于高可靠性火工品的贮存可靠性分析。

关键词：系统评估与可行性分析贮存可靠性火工品时序模型收缩估计

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Evaluation of Erythrocyte Iron Incorporation in Beijing Prepubertal Children Using a Single Stable Isotope Tracer Method

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Biomedical and Environmental Sciences 2020年第6期33卷 414-420页

作者： ZHANG yu LI Ya Jie REN Tong Xiang LIU Xiao Bing YANG Li Chen pao Jian Hua WANG Jurr YANG Xiao Guang Key Laboratory of Trace Element Nutrition MOHChinese Center for Disease Control and PreventionBeijing 100050China Department of Preventive Medicine Changzhi Medical CollegeChangzhi 046000ShanxiChina National Institute of Metrology Beijing 100029China

Objective To analyze the rate of erythrocyte iron incorporation and provided guidance for the iron nutrition for prepubertal *** Fifty-seven prepubertal children of Beijing were involved in this study and each subject was orally administered 3 mg of 57 Fe twice daily to obtain a total of 30 mg 57 Fe after a 5-d period. The stable isotope ratios in RBCs were determined in 14 th day, 28 th day, 60 th day, and 90 th day. The erythrocyte incorporation rate in children was calculated using the stable isotope ratios, blood volume and body iron *** The percentage of erythrocyte 57 Fe incorporation increased starting 14 th day, reached a peak at 60 d(boys: 19.67% ± 0.56%, girls: 21.33% ± 0.59%) and then decreased. The erythrocyte incorporation rates of 57 Fe obtained for girls in 60 th day was significantly higher than those obtained for boys(P < 0.0001).Conclusions The oral administration of 57 Fe to children can be used to obtain erythrocyte iron incorporation within 90 d. Prepubertal girls should begin to increase the intake of iron and further studies should pay more attention to the iron status in prepubertal children.

关键词： Stable isotope tracer technique Iron Erythrocyte incorporation rate Beijing prepubertal children MC-ICP-MS

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