检索结果-南通市图书馆

On the Application of PCA Technique to Fault Diagnosis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tsinghua science and Technology 2010年第2期15卷 138-144页

作者： DING s ZHANG P DING E yin s Naik A DENG P GUI W Institute for Automatic Control and Complex systems (AKs) University of Duisburg-Essen 47057 Duisburg Germany Department of Physical Engineering University of Applied Sciences Gelsenkirchen 45877 Gelsenkirchen Germany school of Information science and Engineering Central South University Changsha 410083 China

In this paper, we bdefly address the application of the standard principal component analysis （PCA） technique to fault detection and identification. Based on an analysis of the existing test statistic, we propose a new test statistic, which is similar to the Hawkin＇s T2 H statistic but without the numerical drawback. In comparison with the sPE index, the threshold setting associated with the new statistic is computationally simpler. Our further study is dedicated to the analysis of fault sensitivity. We consider the off-set and scaling faults, and evaluate the test statistic by viewing its sensitivity to the faults. Our final study focuses on identifying off-set and scaling faults. To this end, two algorithms are proposed. This paper also includes some critical remarks on the application of the PCA technique to fault diagnosis.

关键词： process monitoring fault diagnosis principal component analysis (PCA) multivariate analysis

THE ELECTROCHEMICAL BEHAVIOR OF OCEANIC MICROBIOLOGICAL INFLUENCED CORROsION ON CARBON sTEEL

在线全文

学校读者我要写书评

暂无评论

Acta Metallurgica sinica(English Letters) 2007年第5期20卷 334-340页

作者： X.T. Chang Y.s. yin G.H. Niu T. Liu s. Cheng s.B. sun Institute of Materials science and Technology Ocean University of China Qingdao 266003 China College of Materials science and Technology Shandong University Jinan 250061 China

The corrosion behavior of carbon steel in the medium of marine microorganisms was investigated by electrochemical impedance spectra, polarization curves, and so on. Experimental results showed that the corrosion potential of carbon steel moved in a negative direction in the unpurified marine microorganism solution, and the polarization style of the cathodic process did not change. The electrochemical impedance spectra showed that the impedance value of the electrode decreased in the medium with bacteria, which indicated that the existence of microorganism could accelerate the corrosion progress of carbon steel.

关键词： carbon steel microbiological influenced corrosion polarization curve electrochemical impedance spectroscopy

Nanomaterials-mediated lysosomal regulation:a robust protein-clearance approach for the treatment of Alzheimer’s disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 424-439页

作者： Mengqi Hao Jianjian Chu Tinglin Zhang Tong yin Yuankai Gu Wendanqi Liang Wenbo Ji Jianhua Zhuang Yan Liu Jie Gao You yin Department of Neurology Second Affiliated Hospital of Naval Medical University(Shanghai Changzheng Hospital)ShanghaiChina school of Health science and Engineering University of Shanghai for Science and TechnologyShanghaiChina Changhai Clinical Research Unit Shanghai Changhai HospitalNaval Medical UniversityShanghaiChina Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Neurology Shanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina

Alzheimer’s disease is a debilitating,progressive neurodegenerative disorder characterized by the progressive accumulation of abnormal proteins,including amyloid plaques and intracellular tau tangles,primarily within the ***,crucial intracellular organelles responsible for protein degradation,play a key role in maintaining cellular *** studies have suggested a link between the dysregulation of the lysosomal system and pathogenesis of neurodegenerative diseases,including Alzheimer’s *** the normal physiological function of lysosomes hold the potential to reduce the pathological burden and improve the symptoms of Alzheimer’s ***,the efficacy of drugs in treating Alzheimer’s disease is limited,with major challenges in drug delivery efficiency and ***,nanomaterials have gained widespread use in Alzheimer’s disease drug research owing to their favorable physical and chemical *** review aims to provide a comprehensive overview of recent advances in using nanomaterials(polymeric nanomaterials,nanoemulsions,and carbon-based nanomaterials)to enhance lysosomal function in treating Alzheimer’s *** review also explores new concepts and potential therapeutic strategies for Alzheimer’s disease through the integration of nanomaterials and modulation of lysosomal *** conclusion,this review emphasizes the potential of nanomaterials in modulating lysosomal function to improve the pathological features of Alzheimer’s *** application of nanotechnology to the development of Alzheimer’s disease drugs brings new ideas and approaches for future treatment of this disease.

关键词： Alzheimer’s disease autophagy dysfunction lysosomal acidification lysosomal system nanomaterials neurodegenerative diseases

Evaluation of The severity of Traumatic Hemothorax by CT

在线全文

学校读者我要写书评

暂无评论

Evaluation of The Severity of Traumatic Hemothorax by CT

接尘、吸烟者死亡危险度比较的前瞻性队列研究

The Fifth China International Congress on Thoracic and Cardiovasculal surgery

作者： shi shiqing yin County People’s Hospital of Ningbo City Zhejinag Province

＜正＞ Objective:To explore a scientific evaluation of the severity of traumatic hemothorax in emergencyby means of ***:Between October,1995 and April,1999,78 patients with acute traumat-ic hemothorax（hemo-pneumothorax）were analyzed *** all these cases,36 were decid-ed the treatment steps after emergent CT *** to CT findings all patients were di-111

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

中华流行病学杂志 2004年第9期25卷 748-752页

作者：张维森江朝强 Lam T.Hing Ho s.yin 陈清刘薇薇何健民曹民广州市职业病防治院 510620 香港大学社会医学系第一军医大学流行病学教研室

目的比较接尘、吸烟对死亡的影响。方法以1989～1992年广州市实施并建立的职工职业健康监护档案为基础资料,选年龄≥30岁的80987名接尘和无接尘职工为研究对象,进行前瞻性队列研究。结果 (1)队列平均43.5岁,主要为工人、中学文化程度... 详细信息

目的比较接尘、吸烟对死亡的影响。方法以1989～1992年广州市实施并建立的职工职业健康监护档案为基础资料,选年龄≥30岁的80987名接尘和无接尘职工为研究对象,进行前瞻性队列研究。结果 (1)队列平均43.5岁,主要为工人、中学文化程度、已婚,接尘率16.3％,吸烟率43.7％,饮酒率33.5％。(2)队列平均随访8年,失访35人,死亡1539人,以恶性肿瘤死亡为主。(3)调整相关混杂因素后,全死因、恶性肿瘤、心脑血管疾病等死亡相对危险度(RR),接尘者和吸烟者基本一致,但鼻咽癌、呼吸系统疾病死亡RR值,接尘者高于吸烟者,而肺癌、胃癌死亡RR值,吸烟者分别是接尘者的2.2倍和1.5倍;接尘可协同吸烟致死亡危险性明显增加。(4)男性总死因、恶性肿瘤和呼吸系统疾病死亡RR值,矽尘接触者高于吸烟者,心脑血管疾病死亡RR值,木尘接触者也高于吸烟者。(5)人群死亡归因危险度百分比(PARP)吸烟者是接尘者的2.5倍。(6)男吸烟者全死因、恶性肿瘤、肺癌、胃癌的死亡危险随日吸烟量、烟龄的增加而明显递增,冠心病、呼吸系统疾病的死亡危险则分别随日吸烟量、烟龄的增加而增加。结论接尘、吸烟者死亡RR值基本一致,接尘与吸烟存在协同作用,某些死因死亡危险吸烟者较明显,某些接尘者较明显;吸烟者PARP较接尘者高;吸烟与死亡危险存在明显的剂?

关键词：接尘吸烟死亡危险度职业卫生不良生活习惯

PREPARATION AND sURFACE CHARACTERIZATION OF TiO2 THIN FILMs ON GLAss BY MAGNETRON sPUTTERING METHOD

在线全文

学校读者我要写书评

暂无评论

Acta Metallurgica sinica(English Letters) 2002年第2期15卷 207-209页

作者： L.s.yin1,3), H. shen2) and J.X. Zhang3) 1)College of Information Engineering, Central south University, Changsha 410075, China 2)Guangzhou Institute of Energy Conversion, CAs, Guangzhou 510070, China 3)Department of Physics, Zhongshan University, Guang College of Information Engineering Central South University Changsha 410075 China

Ti thin films were firstly deposited on glass substrates by magnetron sputtering method, then sintered the Ti thin films in air atmosphere and finally TiO2 transparence thin films on glass substrates were obtained. The structure and surface morphologies of the thin films were characterized by X-ray diffraction and sEM. The growth process of the thin films has been observed. The annealing time and annealing temperatures have an affect on the growth of the films.

关键词： TiO2. thin film. magnetron sputtering

Neuronal regulated cell death in aging-related neurodegenerative diseases:key pathways and therapeutic potentials

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2245-2263页

作者： Run song shiyi yin Jiannan Wu Junqiang Yan Department of Neurology The First Affiliated HospitalCollege of Clinical Medicine of Henan University of Science and TechnologyLuoyangHenan ProvinceChina Neuromolecular Biology Laboratory The First Affiliated HospitalCollege of Clinical Medicine of Henan University of Science and TechnologyLuoyangHenan ProvinceChina

Regulated cell death(such as apoptosis,necroptosis,pyroptosis,autophagy,cuproptosis,ferroptosis,disulfidptosis)involves complex signaling pathways and molecular effectors,and has been proven to be an important regulatory mechanism for regulating neuronal aging and ***,excessive activation of regulated cell death may lead to the progression of aging-related *** review summarizes recent advances in the understanding of seven forms of regulated cell death in age-related ***,the newly identified ferroptosis and cuproptosis have been implicated in the risk of cognitive impairment and neurodegenerative *** forms of cell death exacerbate disease progression by promoting inflammation,oxidative stress,and pathological protein *** review also provides an overview of key signaling pathways and crosstalk mechanisms among these regulated cell death forms,with a focus on ferroptosis,cuproptosis,and *** instance,FDX1 directly induces cuproptosis by regulating copper ion valency and dihydrolipoamide s-acetyltransferase aggregation,while copper mediates glutathione peroxidase 4 degradation,enhancing ferroptosis ***,inhibiting the Xc-transport system to prevent ferroptosis can increase disulfide formation and shift the NADP^(+)/NADPH ratio,transitioning ferroptosis to *** insights help to uncover the potential connections among these novel regulated cell death forms and differentiate them from traditional regulated cell death *** conclusion,identifying key targets and their crosstalk points among various regulated cell death pathways may aid in developing specific biomarkers to reverse the aging clock and treat age-related neurodegenerative conditions.

关键词： apoptosis autophagy cuproptosis disulfidptosis ferroptosis necroptosis neurodegenerative disease neurological aging diseases PANoptosis pyroptosis

Unleashing the Potential of Electroactive Hybrid Biomaterials and self‑Powered systems for Bone Therapeutics

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 463-497页

作者： shichang Liu Farid Manshaii Jinmiao Chen Xinfei Wang shaolei Wang Junyi yin Ming Yang Xuxu Chen Xinhua yin Yunlei Zhou Honghui Hospital Xi’an Jiaotong UniversityXi’an 710018People’s Republic of China Department of Bioengineering Henry Samueli School of Engineering and Applied ScienceUniversity of California Los AngelesLos Angeles 90095USA Hangzhou Institute of Technology Xidian UniversityHangzhou 311231People’s Republic of China

The incidence of large bone defects caused by traumatic injury is increasing worldwide,and the tissue regeneration process requires a long recovery time due to limited self-healing *** bioelectrical phenomena have been well recognized as critical biophysical factors in bone remodeling and *** by bioelectricity,electrical stimulation has been widely considered an external intervention to induce the osteogenic lineage of cells and enhance the synthesis of the extracellular matrix,thereby accelerating bone *** ongoing advances in biomaterials and energy-harvesting techniques,electroactive biomaterials and self-powered systems have been considered biomimetic approaches to ensure functional recovery by recapitulating the natural electrophysiological microenvironment of healthy bone *** this review,we first introduce the role of bioelectricity and the endogenous electric field in bone tissue and summarize different techniques to electrically stimulate cells and ***,we highlight the latest progress in exploring electroactive hybrid biomaterials as well as self-powered systems such as triboelectric and piezoelectric-based nanogenerators and photovoltaic cell-based devices and their implementation in bone tissue ***,we emphasize the significance of simulating the target tissue’s electrophysiological microenvironment and propose the opportunities and challenges faced by electroactive hybrid biomaterials and self-powered bioelectronics for bone repair strategies.

关键词： Electroactive biomaterials self-powered bioelectronics Bone regeneration Bone tissue

Multiple liver metastases of unknown origin:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第1期17卷 233-238页

作者： ying-Jin Wang Ze-Chuan Liu Jian Wang yin-Mo Yang Department of Hepatobiliary Pancreatic surgery Peking University First HospitalBeijing 100034China Department of Interventional and Vascular surgery Peking University First HospitalBeijing 100034China

BACKGROUND The liver is the most common site of digestive system tumor metastasis,but not all liver metastases can be traced back to the primary *** it is unusual,syphilis can impact the liver,manifesting as syphilitic hepatitis with inflammatory nodules,which might be misdiagnosed as *** sUMMARY This case report involves a 46-year-old female who developed right upper abdominal pain and intermittent low fever that persisted for more than three *** definitive diagnosis of a tumor had been made in the past decades,but signs of multiple liver metastases were recognized after a computed tomo-graphy scan without evidence of primary *** positive serological tests for syphilis and a biopsy of the liver nodules,a diagnosis of hepatic syphilis was made and confirmed with follow-up nodule reduction after anti-syphilis *** Clinicians must be aware of the possibility that syphilis can cause hepatic inflam-matory masses,especially when liver metastasis is suspected without evidence of primary lesions.A definitive diagnosis should be established in conjunction with a review of the patient’s medical history for accurate therapeutic intervention.

关键词： syphilitic hepatitis Liver nodules Liver metastasis Treponema pallidum Case report