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大连梭鱼湾足球场罩棚结构健康监测及应用

建筑结构学报 2024年第3期45卷 92-100页

作者：张照博任亮李宏男郑帅周光毅伊廷华大连理工大学建设工程学部辽宁大连116024 中国建筑第八工程局有限公司上海200135

大连梭鱼湾足球场的屋盖结构是基于张拉结构延拓的一种自平衡外凸形轮辐式索网结构。为保证延拓设计后的结构安全和解决新型大跨空间结构形式健康监测的重点及难点,针对大连梭鱼湾足球场的罩棚结构建立了由结构层、传感层、数据采集与... 详细信息

大连梭鱼湾足球场的屋盖结构是基于张拉结构延拓的一种自平衡外凸形轮辐式索网结构。为保证延拓设计后的结构安全和解决新型大跨空间结构形式健康监测的重点及难点,针对大连梭鱼湾足球场的罩棚结构建立了由结构层、传感层、数据采集与分析层组成的结构健康监测系统,动态监测结构在多种环境荷载下的实时响应。获取了外荷载由索撑体系中的径向承重索传递至外环柱撑体系中摇摆柱和柱间人字斜撑的体系间荷载传递路径,以及索撑体系中“稳定索-撑杆-承重索”和柱撑体系中“摇摆柱-斜撑”的荷载传递路径和协同受力响应。结果表明,由健康监测系统获取的拉索与重要连接构件在七级风荷载和温度荷载下的索力分别为45kN和85kN,可用于实时评估结构的安全状态。此外,克服温度影响误差的长期监测结果显示结构的最大应力变化约为3MPa。

关键词：大连梭鱼湾足球场结构健康监测索力应力长期监测

Structural regulation of coal-derived hard carbon anode for sodium-ion batteries via pre-oxidation

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Rare Metals 2024年第6期43卷 2585-2596页

作者： Meng-Yuan Su Kai-Yang Zhang Edison Huixiang Ang Xue-li Zhang Yan-Ning liu Jia-lin Yang Zhen-yi gu Faaz A.Butt Xing-Long Wu faculty of Chemistry Northeast Normal UniversityChangchun 130024China MOE Key Laboratory for UV light-Emiting Materials and technology.Northeast Normal University.Ministry of Education Changchun 130024China Natural Sciences and Science Education National Institute of EducationNanyang Technological UniversitySingapore 637616Singapore Materials engineering Department NED University of Engineering and TechnologyKarachi 75300Pakistan

Hard carbon(HC)is broadly recognized as an exceptionally prospective candidate for the anodes of sodium-ion batteries(SIBs),but their practical implementation faces substantial limitations linked to precursor factors,such as reduced carbon yield and increased ***,a cost-effective approach is proposed to prepare a coal-derived HC anode with simple pre-oxidation followed by a post-carbonization process which effectively expands the d_(002.layer spacing,generates closed pores and increases defect *** these modifications,the resulting HC anode attains a delicate equilibrium between plateau capacity and sloping capacity,showcasing a remarkable reversible capacity of 306.3 mAh·g^(-1)at 0.03 A·g^(-1).Furthermore,the produ ced HC exhibits fast reaction kinetics and exceptional rate performance,achieving a capacity of 2.9 mAh·g^(-1)at 0.1 A·g^(-1),equivalent to~94.5%of that at 0.03 A·g^(-1).When implemented in a full cell configuration,the impressive electrochemical performance is evident,with a notable energy density of 410.6 Wh·kg^(-1)(based on cathode mass).In short,we provide a straightforward yet efficient method for regulating coal-derived HC,which is crucial for the widespread use of SIBs anodes.

关键词： Sodium-ion batteries Hard carbon Anode Coal Pre-oxidation

Grading severity of microscopic vascular invasion was independently associated with recurrence and survival following hepatectomy for solitary hepatocellular carcinoma

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Hepatobiliary Surgery and Nutrition 2024年第1期13卷 16-28页

作者： Lan-Qing Yao Chao li Yong-Kang Diao Lei liang Hang-Dong Jia Shi-Chuan Tang Yong-yi Zeng Han Wu ming-Da Wang li-Hui gu Timothy MPawlik Wan Yee Lau Cheng-Wu Zhang Feng Shen Kui Wang Tian Yang Department of Hepatobiliary Surgery Eastern Hepatobiliary Surgery HospitalSecond Military Medical University(Navy Medical University)ShanghaiChina Department of General Surgery Cancer CenterDivision of Hepatobiliary and Pancreatic SurgeryZhejiang Provincial People’s HospitalAffiliated People’s HospitalHangzhou Medical CollegeHangzhouChina Department of Hepatobiliary Surgery Mengchao Hepatobiliary HospitalFujian Medical UniversityFuzhouChina Department of Surgery Ohio State UniversityWexner Medical CenterColumbusOHUSA faculty of Medicine the Chinese University of Hong KongShatinNew TerritoriesHong KongChina Eastern Hepatobiliary Clinical Research Institute Third Affiliated Hospital of Navy Medical UniversityShanghaiChina

Background:Hepatectomy is the preferred treatment for solitary hepatocellular carcinoma(HCC)without macrovascular invasion and distant metastasis,but long-term survival remains unsatisfactory in certain *** sought to identify whether the grading severity of microscopic vascular invasion(MVI)was associated with recurrence and survival among patients with solitary ***:Consecutive patients who underwent hepatectomy for solitary HCC were identified from a multicenter prospectively-collected *** were categorized into three groups according to the MVI grading system proposed by the liver Cancer Pathology Group of china:M0(no MVI),M1(1-5 sites of MVI occurring≤1.0 cm away from the tumor),and M2.>5 sites occurring≤1.0 cm or any site occurring>1 cm away from the tumor).Recurrence-free survival(RFS)and overall survival(OS)were compared among the ***:Among 2.7 patients,97(42.7%),83(36.6%),and 47(2..7%)patients had M0,M1,and M2.*** RFS rates among patients with M0,M1,and M2.were 38.3,35.1,11.6 months,respectively,while OS rates were 66.8,62.3,30.6 months,respectively(both P1).Multivariate Cox-regression analyses demonstrated that both M1 and M2.were independent risk factors for RFS(hazard ratio 1.2.,95%CI:1.03-1.89,P=0.040;and hazard ratio 1.67,95%CI:1.06-2.64,P=0.02.)and OS(hazard ratio 1.2.,95%CI:1.05-2.07,P=0.035;and hazard ratio 1.97,95%CI:1.15-3.38,P=0.013).Conclusions:Grading severity of MVI was independently associated with RFS and OS after hepatectomy for solitary *** surveillance for recurrence and potentially adjuvant therapy may be considered for patients with MVI,especially individuals with more severe MVI grading(M2..

关键词： Hepatocellular carcinoma microscopic vascular invasion recurrence survival hepatectomy

Persistent organic pollutants and chemicals of emerging Arctic concern in the Arctic environment

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Environmental Science and Ecotechnology 2024年第2期18卷 1-3页

作者： yi-Fan li Roland Kallenborn Zifeng Zhang International Joint Research Center for Persistent Toxic Substances(IJRC-PTS) State Key Laboratory of Urban Water Resource and EnvironmentHarbin Institute of TechnologyHarbin 150090China International Joint Research Center for Arctic Environment and Ecosystem(IJRC-AEE) Polar AcademyHarbin Institute of Technology(PA-HIT)Harbin 150090China Heilongjiang Provincial Key Laboratory of Polar Environment and Ecosystem(HPKL-PEE) Harbin 150090China IJRC-PTS-NA TorontoONM2J 3N8Canada faculty of Chemistry Biotechnology and Food Sciences(KBM)Norwegian University of Life Sciences(NMBU)NOe1433 AsNorway

Environmental pollutants,such as persistent organic pollutants(POPs),enter the Arctic mainly via long-range transport(LRT)through atmospheric and ocean/river *** the other hand,chemicals of emerging Arctic concern(CEACs)are often introduced as local contaminants from industrial,municipal,or infrastructure-related *** of their origins,all these contaminants negatively impact the health of the environment and the indigenous ***,in recent decades,the Arctic has been experiencing unprecedented climate *** combination of Arctic environmental changes and the introduction of new anthropogenic contaminants as chemical aids for exploiting Arctic resources led to a severe imbalance in the Arctic ***,an international consortium of Arctic experts asked for internationally coordinated actions to mitigate the serious problems that environmental pollution causes on Arctic ecosystems and people,according to the Berlin statement[1].

关键词： Arctic statement pollution

Association of Pringle maneuver with postoperative recurrence and survival following hepatectomy for hepatocellular carcinoma: a multicenter propensity score and competing-risks regression analysis

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Hepatobiliary Surgery and Nutrition 2024年第3期13卷 412-424,I0003-I0010页

作者： Shi-Chuan Tang Yong-Kang Diao Kong-ying lin Chao li Xiao Xu Lei liang Jie Kong Qing-Jing Chen Xian-ming Wang Fu-Bao liu Wei-Min gu Ya-Hao Zhou ying-Jian liang Hong-Zhi liu ming-Da Wang Lan-Qing Yao Timothy M.Pawlik Feng Shen Wan Yee Lau Tian Yang Yong-yi Zeng Department of Hepatobiliary Surgery Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhouChina Department of Hepatobiliary Surgery Eastern Hepatobiliary Surgery HospitalNavy Medical University(Second Military Medical University)ShanghaiChina Department of Hepatobiliary Surgery Affiliated Hospital of Nantong UniversityNantongChina Department of Hepatobiliary Surgery People’s Hospital of Zhejiang ProvincialPeople’s Hospital of Hangzhou Medical CollegeHangzhouChina Department of Hepatobiliary Heze Municiple HospitalHezeChina Department of General Surgery First Affiliated Hospital of Shandong First Medical University&Shandong Provincial Qianfoshan HospitalJinanChina Department of Hepatobiliary Surgery First Affiliated Hospital of Anhui Medical UniversityHefeiChina The First Department of General Surgery Fourth Hospital of HarbinHarbinChina Department of Hepatobiliary Surgery Pu’er People’s HospitalPu’erChina Department of Hepatobiliary Surgery First Affiliated Hospital of Harbin Medical UniversityHarbinChina Department of Surgery Ohio State UniversityWexner Medical CenterColumbusOHUSA faculty of Medicine The Chinese University of Hong KongHong KongChina Department of Hepatopancreatobiliary Surgery First Affiliated Hospital of Fujian Medical UniversityFuzhouChina The liver Disease Research Center of Fujian Province FuzhouChina

Background:The application of Pringle maneuver(PM)during hepatectomy reduces intraoperative blood loss and the need for perioperative transfusion,but its effect on long-term recurrence and survival for patients with hepatocellular carcinoma(HCC)remains *** sought to determine the association between the application of PM and post-hepatectomy oncologic outcomes for patients with ***:Patients who underwent curative hepatectomy for HCC at 9 Chinese hospitals from January 2.10 to December 2.18 were *** two propensity score methods[propensity score matching(PSM)and inverse probability of treatment weight(IPTW)],cumulative recurrence rate and cancer-specific mortality(CSM)were compared between the patients in the PM and non-PM *** competing-risks regression models were performed to adjust for the effect of non-cancer-specific mortality and other prognostic risk ***:Of the 2.798 included patients,2.404 and 394 did and did not adopt PM(the PM and non-PM groups),*** rates of intraoperative blood transfusion,postoperative 30-day mortality and morbidity were comparable between the two groups(all P>0.05).In the PSM cohort by the 1:3 ratio,compared to 382.patients in the non-PM group,1,146 patients in the PM group also had the higher cumulative 5-year recurrence rate and CSM(63.9%and 39.1%vs.55.3%and 31.6%,both P2.elded in the entire cohort and the IPTW *** competing-risks regression analyses demonstrated that no application of the PM was independently associated with lower recurrence rate and CSM based on various analytical cohorts[hazard ratio(HR),0.82.and 0.77 in the adjusted entire cohort,HR 0.80 and 0.73 in the PSM cohort,and HR 0.80 and 0.76 in the IPTW cohort,respectively].Conclusions:The findings suggested that no application of PM during hepatectomy for patients with HCC reduced the risk of postoperative recurrence and cancer-specific death by appr

关键词： Hepatocellular carcinoma(HCC) Pringle maneuver(PM) recurrence survival hepatectomy

谷壳灰硅肥改善土壤质量降低水稻镉砷累积的效应

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环境科学 2024年第3期45卷 1793-1802页

作者：易轩韬欧阳坤辜娇峰李倩游萍周航廖柏寒中南林业科技大学环境科学与工程学院长沙410004 湖南浩美安全环保科技有限公司长沙410100 昆明理工大学环境科学与工程学院昆明650504 中南大学资源加工与生物工程学院长沙410083

为研究谷壳灰制备硅肥对水稻不同生育期土壤重金属镉(Cd)和砷(As)生物有效性、酶活性、微生物群落结构和糙米重金属含量的影响,开展水稻盆栽试验.结果表明,施用0.1%~1.0%谷壳灰硅肥能提高土壤pH值0.04~0.2.个单位,有效硅含量44.2.~97.5%... 详细信息

为研究谷壳灰制备硅肥对水稻不同生育期土壤重金属镉(Cd)和砷(As)生物有效性、酶活性、微生物群落结构和糙米重金属含量的影响,开展水稻盆栽试验.结果表明,施用0.1%~1.0%谷壳灰硅肥能提高土壤pH值0.04~0.2.个单位,有效硅含量44.2.~97.5%,也能降低土壤有效态Cd含量16.2.~2..4%,有效态As含量16.0%~2..9%;随施加量的增大各生育期土壤酶活性增大,其中蔗糖酶活性显著增大6.3%~145.7%,脱氢酶活性显著增大6.7%~2.4.1%;分析土壤成熟期微生物群落结构显示,施用谷壳灰硅肥不影响微生物α-多样性,但对微生物β-多样性产生显著影响,促进微生物生长,维持群落结构稳定性;随施加量的增大,糙米Cd含量降低了2..3%~89.7%,糙米总As和无机As含量分别降低7.8%~42.3%和17.2.~44.5%,当施用量在0.5%和1.0%时水稻糙米ω(Cd)2.mg·kg^(-1),ω(无机As)1).综上,谷壳灰硅肥能改善土壤质量、降低糙米Cd和As含量,具有环境友好性,可用于Cd和As复合污染稻田土壤的治理.

关键词：谷壳灰硅(Si) 镉砷水稻土壤酶土壤微生物群落

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一类新的单机工期指派模糊调度算法研究

聊城大学学报（自然科学版） 2024年第4期37卷 1-13页

作者：易国荣李金权顾文豪北京理工大学(珠海)信息学院广东珠海519088 北京师范大学珠海分校应用数学学院广东珠海519087 北京师范大学文理学院广东珠海519087

研究了单机模糊环境下,如何安排工件加工顺序和指定工件工期,使得提前完工和拖期完工惩罚总费用均值最小的工期指派调度优化问题。在该类调度问题中,工件的加工时间为非对称三角模糊数;总费用的均值用模糊数的加权可能性均值来计算。针... 详细信息

研究了单机模糊环境下,如何安排工件加工顺序和指定工件工期,使得提前完工和拖期完工惩罚总费用均值最小的工期指派调度优化问题。在该类调度问题中,工件的加工时间为非对称三角模糊数;总费用的均值用模糊数的加权可能性均值来计算。针对一类权函数族,给出了该类权函数族下的工件最优工期的计算方法,基于该最优工期,给出了排序的最优调度算法,并证明了该类工期设定问题是多项式可解的。数值实验中针对工件完工时间服从不同的非对称分布的情形,与现有的方法比较,结果表明给出的方法能更有效的降低费用。

关键词：工期指派模糊调度非对称三角模糊数

基于血液代谢组学分析缺血性心脏病患者疾病进程的代谢紊乱特征

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质谱学报 2024年第2期45卷 256-268页

作者：杨柱林田林云吴昊李慧敏顾颖任达兵壮可赵燕张宏易伦朝昆明理工大学食品科学与工程学院云南昆明650500 昆明理工大学附属医院云南省第一人民医院心血管内科云南昆明650032 昆明理工大学化学工程学院云南昆明650500 昆明理工大学生命科学学院云南昆明650500

本研究以47例心绞痛患者、51例心肌梗死患者和80例心力衰竭患者的血浆作为样本,结合超高效液相色谱-高分辨质谱(UPLC-HRMS)技术和化学计量学方法,分析缺血性心脏病患者疾病进程的代谢紊乱特征。实验共定性、定量鉴定97种内源性代谢物,基... 详细信息

本研究以47例心绞痛患者、51例心肌梗死患者和80例心力衰竭患者的血浆作为样本,结合超高效液相色谱-高分辨质谱(UPLC-HRMS)技术和化学计量学方法,分析缺血性心脏病患者疾病进程的代谢紊乱特征。实验共定性、定量鉴定97种内源性代谢物,基于t检验、主成分分析、偏最小二乘-判别分析、变量重要性投影等方法,分别筛选出2.种和32.可区分心绞痛与心肌梗死患者,心肌梗死与心力衰竭患者的差异性特征代谢物。代谢通路分析结果表明,从心绞痛到心肌梗死,以及从心肌梗死到心力衰竭的疾病进程中,氨基酸代谢和三羧酸循环等能量代谢均发生了紊乱;从心肌梗死到心力衰竭的疾病进程中,以甘油磷脂代谢和脂肪酸生物合成为代表的脂质代谢显著紊乱;通过分析受试者工作曲线(ROC),糖胆酸、富马酸、棕榈酸、肌钙蛋白、高密度脂蛋白、谷丙转氨酶和谷草转氨酶等联合指标可提高心肌梗死诊断精度,ROC曲线下面积(AUC)值达到1.0000;瓜氨酸、柠檬酸、硬脂酸、甘油磷酸胆碱和NT-proBNP联合指标可提高心力衰竭诊断精度,AUC值达到0.9570。本研究可为缺血性心脏病患者的精准诊断和疾病发展过程中的药物、营养干预提供重要的代谢靶标。

关键词：超高效液相色谱-高分辨质谱(UPLC-HRMS) 代谢组学心绞痛心肌梗死心力衰竭化学计量学

自组装纳米颗粒肿瘤疫苗OVA2.7-2.4-mi3的构建及其保护效果评价

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陆军军医大学学报 2024年第12期46卷 1361-1368页

作者：陈源高晨李宇航崔致远程新张怡于博顾江杨宪重庆师范大学生命科学学院重庆401331 陆军军医大学(第三军医大学)药学与检验医学系重庆400038 陆军军医大学(第三军医大学)第一附属医院骨科重庆400038

目的构建SpyCatcher-mi3纳米颗粒疫苗递送载体,评价其在增强卵清蛋白CD8+T细胞表位肽OVA 2.7-2.4免疫原性和在小鼠荷瘤模型中免疫保护效果。方法SpyCatcher-mi3蛋白由大肠杆菌表达,依次经亲和层析、阴离子交换层析纯化得到;合成OVA 2.7-... 详细信息

目的构建SpyCatcher-mi3纳米颗粒疫苗递送载体,评价其在增强卵清蛋白CD8+T细胞表位肽OVA 2.7-2.4免疫原性和在小鼠荷瘤模型中免疫保护效果。方法SpyCatcher-mi3蛋白由大肠杆菌表达,依次经亲和层析、阴离子交换层析纯化得到;合成OVA 2.7-2.4-SpyTag多肽,通过SpyTag/SpyCatcher蛋白质连接系统构建纳米颗粒OVA 2.7-2.4-mi3;通过细胞溶血实验和细胞毒性实验评价OVA 2.7-2.4-mi3体外安全性,记录小鼠体重变化和镜检脏器组织切片HE染色评价OVA 2.7-2.4-mi3体内安全性;将6~8周龄,18~2. g,SPF级,雌性C57BL/6小鼠按随机数字表法分为OVA 2.7-2.4-mi3组、OVA 2.7-2.4组和Control组,每组14只,分别于第0、14、2.天免疫小鼠,末次免疫后第14天通过EliSpot检测其脾脏淋巴细胞中IFN-γ分泌细胞数量评价其免疫原性;在小鼠荷瘤模型上通过核磁共振成像等手段评价纳米颗粒疫苗OVA 2.7-2.4-mi3的保护效果。结果SpyCatcher-mi3和OVA 2.7-2.4-mi3均自组装形成均一稳定的纳米颗粒,平均粒径约为43.8 nm和91.3 nm;OVA 2.7-2.4-mi3在体内外均具有良好的安全性;OVA 2.7-2.4-mi3组小鼠每1×106个脾脏淋巴细胞中IFN-γ分泌细胞数量达2.3,显著高于OVA 2.7-2.4组(P2.7-2.4-mi3组小鼠第2.天荷瘤体积约151.1 mm 3,显著小于OVA 2.7-2.4组(P2.7-2.4组(P2.7-2.4-mi3,其增强肿瘤抗原表位肽OVA 2.7-2.4免疫原性,在小鼠荷瘤模型中保护效果良好,为肿瘤新抗原疫苗的研究提供了理论基础。

关键词： SpyCatcher-mi3 OVA 2.7-2.4 纳米颗粒疫苗保护效果评价