检索结果-南通市图书馆

Intraplaque injections of hyaluronic acid for the treatment of stable-phase Peyronie’s disease:a retrospective single-center experience

引用

Asian Journal of Andrology 2024年第3期26卷 268-271页

作者： Simone Cilio Roberto La Rocca Giuseppe Celentano Claudio Marino Massimiliano Creta Gianluigi Califano Celeste Manfredi Giorgio Ivan Russo Afonso Morgado Marco Falcone Marco Capece yau working group sexual and reproductive health Department of Neurosciences Reproductive Sciences and OdontostomatologyUrology UnitUniversity of Naples“Federico II”Naples 80131Italy Urology Unit Department of WomenChild and General and Specialized Surgery“Luigi Vanvitelli”UniversityNaples 80131Italy Urology Section Department of SurgeryUniversityof CataniaCatania 95131Italy Department of Urology Centro Hospitalar Universitário São JoãoPorto 4200-319Portugal Urology Clinic-A.O.U.“Cittàdella Salute edella Scienza”-Molinette Hospital University of TurinTurin 10100Italy 不详

Peyronie’s disease(PD)is a condition of penile connective tissue affecting up to 10%of men *** the complexity ofits management,nonsurgical treatments,such as intraplaque injections,are gaining *** current literature shows dataon the efficacy of intraplaque injections of hyaluronic acid(HA)mainly in acute-phase ***,data on injections of HA instable-phase PD are *** for this retrospective study were derived from a prospectively maintained database of privatepatients presenting at a private medical practice affiliated to the University of Naples“Federico II”(Naples,Italy)with stable-phasePD between January 2020 and March *** underwent a standard protocol of three injections,each administered at atwo-week *** the intervals,patients performed vacuum device therapy,penile stretching,and modeling *** compiled the Peyronie’s Disease Questionnaire(PDQ)and Global Assessment of Peyronie’s Disease(GAPD)at baselineand 2 weeks after the third injection.A penile Doppler ultrasound was performed 2 weeks after the last injection to record thefinal ***,we recruited 62 patients with stable-phase PD and a mean(±standard deviation[s.d.])curvature of52.7°(±9.7°).After 6 weeks,eight(12.9%)patients did not experience any curvature *** remaining 54 patientshad a final mean(±s.d.)curvature of 40.3°(±9.1°)with P<0.001,compared to that before *** found improvement inall PDQ domains(all P≤0.01),and 50(80.6%)patients reported subjective improvement of the penile curvature according to *** conclusion,we demonstrated that after three injections of HA administered according to the adopted protocol,patientswith stable-phase PD could experience significant improvements in penile curvature,and physical and psychological consequencesof the disease without significantly relevant side effects.

关键词： hyaluronic acid intraplaque injection Peyronie’s disease stable-phase therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Machine learning approach to assess the association between anthropometric,metabolic,and nutritional status and semen parameters

引用

Asian Journal of Andrology 2024年第4期26卷 349-355页

作者： Guillaume Bachelot Antonin Lamaziere Sebastien Czernichow Celine Faure Chrystelle Racine Rachel Levy Charlotte Dupont Nutrition and Fertility(ALIFERT)group Author Information Sorbonne University School of Medicine Saint-Antoine Research CenterINSERM UMR 93827 rue ChalignyParis 75012France reproductive Biology Department-CECOS Tenon HospitalAP-HP.Sorbonne UniversityParis 75020France Clinical Metabolomics Department Saint-Antoine HospitalAP-HP27 rue ChalignyParis 75012France Nutrition Department Obesity Specialist CentreGeorges Pompidou European HospitalAP-HPParis 75015France 不详

Many lifestyle factors,such as nutritional imbalance leading to obesity,metabolic disorders,and nutritional deficiency,have been identified as potential risk factors for male *** aim of this study was to evaluate the relationship between semen parameters and anthropometric,metabolic and nutritional *** was first assessed individually,then after the application of a previously constructed and validated machine learning score that allows their ***,metabolic,antioxidant,micronutrient,and sperm parameters from 75 men suffering from idiopathic infertility from four infertility centers in France(Jean-Verdier ART Center Hospital,Bondy;North Hospital ART Center,Saint-Étienne;Navarre Polyclinic ART Center,Pau;and Cochin Hospital ART Center,Paris)between September 2009 and December 2013 were *** assessing standard correlation analysis,a previously built machine learning model,providing a score ranging from 0(the poorest)to 1(the most favorable),was calculated for each man in the study *** machine learning model,which separates infertile/fertile men with unexplained infertility on the basis of their bioclinical signature,provides a more holistic evaluation of the influence of the considered markers(anthropometric,metabolic,and oxidative status).We observed a significant correlation of some anthropometric,metabolic,and nutritional disorders with some sperm ***,an unfavorable machine learning score was associated with a high level of sperm DNA *** anthropometric,metabolic,and oxidative patterns,which may reflect an appropriate lifestyle,appear to positively impact overall health,in particular reproductive *** study,consistent with previous publications,suggests that beyond semen quality parameters,in an essential assessment of male fertility,other key factors should be taken into *** this regard,the application of emerging artificial intelligence t

关键词： lifestyle machine learning metabolism nutrition sperm DNA fragmentation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Different sperm sources and parameters can influence intracytoplasmic sperm injection outcomes before embryo implantation

引用

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第1期13卷 1-10页

作者： Yue-hong LU1,2, Hui-juan GAO1, Bai-jia LI1, Ying-ming ZHENG1, Ying-hui YE1, Yu-li QIAN1, Chen-ming XU1, He-feng HUANG1, Fan JIN1 (1Department of reproductive Endocrinology, Key Laboratory of reproductive Genetics, Ministry of Education, and Key Laboratory of Women’s reproductive health of Zhejiang Province, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China) (2Department of reproductive health, Shaoxing Women and Children Hospital, Shaoxing 312000, China) Department of reproductive Endocrinology Key Laboratory of Reproductive Genetics Ministry of Education Women's Hospital School of Medicine Zhejiang University Hangzhou 310006 China.

To evaluate the effects of sperm with different parameters and sources on the outcomes of intracytoplasmic sperm injection (ICSI), 1972 ICSI cycles were analyzed retrospectively. groups 1 to 5 were composed of cycles using ejaculated sperm and were grouped according to sperm quantity, quality, and morphology into normal (288 cycles), or mild (329 cycles), moderate (522 cycles), severe (332 cycles), and extremely severe (171 cycles) oligozoospermia and/or asthenozoospermia and/or teratozoospermia (OAT) groups. group 6 was composed of 250 cycles using testicular or epididymal sperm, and group 7 consisted of 80 cycles using frozen-thawed sperm. We found that fertilization rates were gradually reduced from groups 1 to 6, and reached statistical difference in groups 5 and 6 (Pgroup 1 than in groups 2, 3, 5, 6, and 7 (Pgroups (P>0.05). A total of nine cases of malformation were observed, with a malformation rate of 1.25% (9/719). In conclusion, different sperm sources and parameters can affect ICSI outcomes before embryo implantation. A full assessment of offspring mal-formation will require further study using a larger sample size.

关键词： Intracytoplasmic sperm injection (ICSI)i Sperm Sperm source Sperm parameters Malformation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

IVF成功定义—基于Delphi法的中国专家意见

引用

中华生殖与避孕杂志 2024年第9期44卷 887-897页

作者： IVF成功定义专家组

目的旨在采用Delphi法对体外受精(in vitro fertilization, IVF)成功的定义提出专家意见, 为临床实践提供参考依据。方法采用Delphi法对衡量IVF成功定义进行专家调查, 由8名专家基于相关文献制定陈述框架, 并通过会议讨论细化陈述内容,... 详细信息

目的旨在采用Delphi法对体外受精(in vitro fertilization, IVF)成功的定义提出专家意见, 为临床实践提供参考依据。方法采用Delphi法对衡量IVF成功定义进行专家调查, 由8名专家基于相关文献制定陈述框架, 并通过会议讨论细化陈述内容, 形成陈述初始内容。通过发放调研问卷, 就陈述内容征询23名生殖专家意见。据专家反馈意见对陈述进行修改, 并再次发放问卷, 直至达成共识。结果共进行2轮问卷调查, 专家参与的积极程度分别为100%(23/23)和73.9%(17/23), 专家权威系数为0.895。就IVF成功定义相关的19条陈述达成共识, 主要包括:①IVF治疗的目标(1条陈述), 即安全地尽快获得单胎健康活产。②IVF成功的定义(13条陈述), 包括IVF治疗的有效性、安全性和效率的评估, 单个卵巢刺激周期2年内的累积活产率是衡量IVF治疗成功的绩效指标。衡量IVF成功应从以患者为中心角度出发, 结合患者的负担和满意度进行评价。③IVF成功的保障(3条陈述)。IVF治疗应遵循循证医学证据, 尽量避免在诊疗过程中实施未经证实的、患者获益不明确的治疗方案。辅助生殖机构应通过建立关键技术指标的监测并完善质控体系来优化治疗质量。④IVF成功的挑战(2条陈述)。取卵前取消周期和治疗周期失败后放弃继续治疗是IVF成功不可忽视的挑战。结论基于Delphi法, 结合生殖专家组的临床观点, 就IVF成功的定义形成了专家意见, 可作为临床指南的补充, 用于指导临床实践, 助力改善治疗结局。

关键词：受精, 体外成功率累积活产率

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

sexual Behaviour of Rural College Youth in Maharashtra, India: An Intervention Study

引用

Journal of Reproduction and Contraception 2008年第3期19卷 167-189页

作者： Mohan Ghule Balaiah Donta National Institute for Research in reproductive health Mumbai 400012 Maharashtra India

Objective To promote healthy sexual behaviour among rural college youth. Methods The intervention study consisted a sample of 1 500 （800 male and 700female） in baseline and 1 953 （1 022 male and 931 female） college going students in post intervention, in the age groups 15-24 years from 8 colleges in Thane district of Maharashtra. The interventions included dissemination of lEC （Information, Education and Communication）, counselling in colleges and provision of health care services at rural health centers in the experimental area. Male and female teachers and peer leaders were trained to provide IEC. Chi-square test was carried out to find out the association between contributing factors and sexual behaviour. Results Post intervention results showed that overall any sexual experience （coital/ non-coital） increased by 2.6% and 1.0% among male students and 4.6% and 0.8% among female students in control and experimental groups respectively which suggests that in the control area physical closeness and sexual relationship has increased between sexes. A significant improvement was noted in the usage of condom during their sexual intercourse in experimental group. The provision of IEC in college settings, peer leader training and orientation to teachers helped students and teachers to initiate a dialogue on reproductive health issues. Intervention programs helped college youth to develop the skills, make informed decisions about engaging in sexual intercourse and using contraceptives in a social context that sometimes encourages risky sexual behaviour. The study found that peer interaction was exposure to erotic material; habits and working status among boys and peer interaction and place of study among girls were closely associated with their coital and non-coital sex experience. Conclusion A scientifically developed, need based and demand driven reproductive health service package for male and female students in colleges can help them to develop their knowledge, sk

关键词： sexual behaviour rural youth interventions reproductive health youth sexuality sexual health

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

中国杜氏肌营养不良携带者筛查的临床实践指南

引用

国际神经病学神经外科学杂志 2024年第1期51卷 1-6页

作者：《中国杜氏肌营养不良携带者筛查的临床实践指南》制订组杨飞曹雅不详解放军总医院第一医学中心

杜氏肌营养不良(DMD)是一种X连锁隐性遗传的单基因病,多以男性起病,表现为严重的、进行性加重的肌无力。其致残致死性高,目前尚无有效治疗。越来越多的临床证据表明,女性携带者亦可出现不同程度的临床症状。因此,DMD携带者筛查是降低患... 详细信息

杜氏肌营养不良(DMD)是一种X连锁隐性遗传的单基因病,多以男性起病,表现为严重的、进行性加重的肌无力。其致残致死性高,目前尚无有效治疗。越来越多的临床证据表明,女性携带者亦可出现不同程度的临床症状。因此,DMD携带者筛查是降低患儿出生率的关键。该实践指南目的旨在快速明确DMD的病因,及早干预,并指导家系成员再生育,进一步促进DMD的规范化防控。

关键词：杜氏肌营养不良杜氏肌营养不良携带者 X连锁隐性遗传病遗传咨询临床实践指南

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Birth Defects in Assisted reproductive Technology and Spontaneously Conceived Children:A Meta-analysis

引用

Journal of Reproduction and Contraception 2013年第4期24卷 237-252页

作者： Yan JIA Li-hong GENG Ying ZHONG reproductive Centre Jinjiang Maternal and Child Health Hospital

Objective To evaluate the risk of birth defects in children born following assisted reproductive technology （ART） and spontaneous conceptions. Methods This study carried out an updated systematic review to identify papers published by August 2013 with data relating to birth defects of children conceived using ART （IVF and for ICSI） compared with those spontaneously conceived and also compared birth defects between subgroups of lVF and ICSI. Results Totally 76 studies were identified for review. The individual relative risk （RR） estimated for these studies ranged from 0.44 to 5.51, a signifieantly increased risk of birth defects was observed （RR=l.36, 95%CI=1.25-1.47） in ART compared with the spontaneously conceived group, which was also evident in the subgroup analysis. Among these studies, 16 studies simultaneously gave data of birth defects comparing IVF and ICSI children, which showed no difference in risk of combined effects （RR=0.90, 95%CI=0.80 1.02）, but ICSI had a higher risk in subgroups of clinical research （RR=O. 76, 95%CI=0.65-0.89） and crude RR value （RR=O. 78, 95%CI=0.67 0.91）. Conclusion Pooled results from all suitable published studies suggested that children born following ART were at increased risk of birth defects compared with spontaneous conceptions. There is no difference in birth defect risk between children conceived by IVF or 1CS1 using a summative analysis, however, 1CS1 had a significant higher risk in birth defect risk comparing with 1VF when using subgroup analyses of sample size and RR value.

关键词： birth defects assisted reproductive technology (ART) IVF ICSI Meta-analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

青春期多囊卵巢综合征诊治共识

引用

生殖医学杂志 2016年第9期25卷 767-770页

作者： reproductive Endocrinology group,Chinese Maternal & Child health Industry Association,National Association of health Industry & Enterprise Management 全国卫生产业企业管理协会妇幼健康产业分会生殖内分泌学组

对于青春期女性的多囊卵巢综合征(PCOS),目前国内外尚无公认的统一诊断标准,且治疗方案的选择也不尽相同。为使国内各级妇产科医师更好地诊治和管理青春期PCOS患者,更新知识,并与国际接轨,国内该领域的专家在参考国外相关共识及指南后,... 详细信息

对于青春期女性的多囊卵巢综合征(PCOS),目前国内外尚无公认的统一诊断标准,且治疗方案的选择也不尽相同。为使国内各级妇产科医师更好地诊治和管理青春期PCOS患者,更新知识,并与国际接轨,国内该领域的专家在参考国外相关共识及指南后,结合我国的具体情况,编写了"青春期多囊卵巢综合征诊治共识",以改变临床医生对PCOS的传统认识,达到规范诊断和治疗青春期PCOS患者的目的。

关键词：青春期女性多囊卵巢综合征诊断及治疗专家共识

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of Exposure to Trinitrotoluene on Male Reproduction

引用

Biomedical and Environmental Sciences 1993年第2期6卷 154-160页

作者： LI YI, JIANG QUAN-GUAN, YAO SHOU-QI, LIU WEI, TIAN GAO-JUN,AND GUI JING-WEIDepartment of Occupational health, School of Public health, Beijing Medical University, Beijing ^Hebi Institute of Occupational health, Henan Province Anyang Institute of Occupational health, Henan Province Xinxiang Institute of Occupational health, Henan Province, China Prof. Jiang Quan-guan, Department of Occupational health, School of Public health, Beijing Medical University, Beijing 100083 China. Department of Occupational health School of Public Health Beijing Medical University China.

A cross-sectional study was performed in 2 plants located in Henan Province in 1990 for observing the reproductive and sexual functions of male workers exposed to trinitrotoluene (TNT). The TNT concentrations in the workplace air, except the packing site, were found to have exceeded MAC (1 mg/m3). TNT exposed male workers complained of more sexual disorders such as impotence, the loss of libido and sexual hypoesthesia than the control group. Compared with the control group, the volume of semen and percentage of motile spermatozoawere found to have significantly decreased, and the sperm malformation incidence increased significantly in TNT exposed workers. The serum testosterone content in TNT exposed male workers was significantly decreased too.

关键词： TNT

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

辅助生殖助孕患者妊娠风险等级评估标准及使用建议

引用

中华生殖与避孕杂志 2024年第7期44卷 668-678页

作者：辅助生殖助孕患者妊娠风险评估标准及使用建议编写组李蓉杨蕊陈立雪潘宁宁尚䴖周雯慧陈亮孙正怡韩红敬马延敏耿琳琳王颖杨晓葵赵连明王慧春吴红萍乔杰不详北京大学第三医院妇产科生殖医学中心国家妇产疾病临床研究中心北京市人类辅助生殖技术质量控制和改进中心北京大学第三医院国家妇产疾病临床研究中心北京大学第一医院首都医科大学附属北京朝阳医院北京协和医院北京大学人民医院首都医科大学附属北京妇产医院国家卫生健康委科学技术研究所北京市海淀区妇幼保健院北京大学

人类辅助生殖技术(assisted reproductive technology,ART)是运用医学技术和方法对配子、合子、胚胎进行人工操作,以达到受孕目的的技术。为加强医疗质量安全管理,保障接受ART治疗患者助孕期间及妊娠期的安全,北京市人类辅助生殖技术质... 详细信息

人类辅助生殖技术(assisted reproductive technology,ART)是运用医学技术和方法对配子、合子、胚胎进行人工操作,以达到受孕目的的技术。为加强医疗质量安全管理,保障接受ART治疗患者助孕期间及妊娠期的安全,北京市人类辅助生殖技术质量控制和改进中心结合国家卫生健康委员会印发的孕产妇妊娠风险评估与管理工作规范(孕产妇妊娠风险评估五色球管理),拟定本标准及其使用建议。本评估方法通过对接受辅助生殖治疗的女性进行妊娠相关风险的筛查、评估和管理,及时发现并干预相关风险因素,防范不良妊娠结局,保障母婴安全。

关键词：生殖技术,辅助妊娠风险评估专家建议

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：