检索结果-南通市图书馆

Chinese Journal of Structural Chemistry 2021年第6期40卷 767-774,685页

作者： JU Hai-Yan yang Ming ZHANG Gang LIU De-Zheng yang yong-sheng ZHANG Yan-Bo School of Chemistry and Engineering Wuhan Textile UniversityWuhan 430073China Hubei Key Laboratory of Biomass Fibers and Eco-dyeing&Finishing Wuhan Textile UniversityWuhan 430073China Hubei Key Laboratory of Power System Design and Test for Electrical Vehicle Hubei University of Arts and ScienceXiangyang 441053China

One-dimensional(1D)chiral chain complexes[CuLSCu(Pydc)](2S)and[CuLRCu(Pydc)](2R)(LS=(E)-3-(((1S,2S)-2-(((E)-3-oxo-3-(4-pyridin-4-yl)phenyl)propylidene)amono)-1,2-diphenyl)imino)-1-(4-(py-ridi-4-yl)phenyl)butan-1-one)and LR=(E)-3-(((1R,2R)-2-(((E)-3-oxo-3-(4-pyridin-4-yl)phenyl)propyli-dene)amono)-1,2-diphenyl)imino)-1-(4-(pyridi-4-yl)phenyl)butan-1-one and Pydc=2,6-pyridinedicarboxylic acid)have been synthesized vis mononuclear chiral enantiomer precursors CuLS(1S)and CuLR(1R).Their different chiral configurations of 1S,1R,2S and 2R were determined by single-crystal X-ray diffraction analyses and further characterized by elemental analyses,infrared spectra(IR),powder X-ray diffraction(PXRD),thermal gravimetric analyses(TGA)and circular dichroism spectra(CD).

关键词： mononuclear chiral precursors 1D chiral chain circular dichroism spectra

Effects of long-term grazing exclusion on vegetation structure,soil water holding capacity,carbon and nitrogen sequestration capacity in an alpine meadow on the Tibetan Plateau

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Journal of Mountain Science 2023年第3期20卷 779-791页

作者： yang yong-sheng ZHANG Fa-wei XIE Xian-rong WANG Jun-bang LI Ying-nian HUANG Xiao-tao LI Hui-ting ZHOU Hua-kun Key Laboratory of Adaptation and Evolution of Plateau Biota and Key Laboratory of Restoration Ecology in Cold Region of Qinghai Province Northwest Institute of Plateau BiologyChinese Academy of SciencesXining 810008China Qinghai Haibei National Field Research Station of Alpine Grassland Ecosystem Xining 810008China Xi Ning Municipal Beishan Forestry Farm Xining 810003China Institute of Geographic Sciences and Natural Resources Research Chinese Academy of SciencesBeijing 100101China

Grazing exclusion is one of the primary management practices used to restore degraded grasslands on the Tibetan ***,to date,the effects of long-term grazing exclusion measures on the process of restoring degraded alpine meadows have not been *** this study,moderately degraded plots,in which the vegetation coverage was approximately 65%and the dominant plant species was Potentilla anserina L,with grazing exclusion for 2 to 23 years,were selected in alpine meadows of Haibei in Qinghai-Tibet *** coverage,plant height,biomass,soil bulk density,saturated water content,soil organic carbon(SOC)and total nitrogen(TN)were *** results were as follows:(1)With aboveground biomass and total saturated water content at 0-40 cm depth,the average SOC and TN contents in moderately degraded alpine meadows increased as a power function,and the plant height increased as a log function.(2)The average soil bulk density at 0-40 cm depth first decreased and then increased with increasing grazing exclusion duration,and the minimum value of 0.90 g·cm^(-3) was reached at 15.23 *** plant coverage,total belowground biomass at 0-40 cm depth,total aboveground and belowground biomass first increased and then decreased,their maximum values(80.49%,2452.92g·m^(-2),2891.06 g·m^(-2))were reached at 9.41,9.46 and 10.25 years,***-term grazing exclusion is apparently harmful for the sustainable restoration of degraded alpine *** optimal duration of grazing exclusion for the restoration of moderately degraded alpine meadows was 10 *** research suggests that moderate disturbance should be allowed in moderately degraded alpine meadows after 10years of grazing exclusion.

关键词： Long-term grazing exclusion Soil water holdingcapacity Soilcarbonand nitrogen sequestration Biomass Alpine meadow

The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop

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Chinese Journal of Natural Medicines 2021年第11期19卷 815-824页

作者： CHEN Yao-Dong CAI Fang-Yu MAO Yu-Ze yang yong-sheng XU Kun LIU Xiao-Fang FAN Wen-Wen CHEN Wu JIANG Feng-Qi ZHANG Hui Department of Ultrasonic Imaging the First Hospital of Shanxi Medical UniversityTaiyuan 030001China Department of Radiology the First Clinical Medical CollegeShanxi Medical UniversityTaiyuan 030001China Department of Thoracic Surgery the General Hospital of Heilongjiang Province Land Reclamation BureauHarbin 150088China Department of Cardio-Thoracic Surgery the First Affiliated Hospital of Jiamusi UniversityJiamusi 154000China Department of General Surgery Heilongjiang Provincial HospitalHarbin 150001China

Cervical cancer(CC)is recognized as the most common neoplasm in the female reproductive system *** lack of chemotherapeutic agents with outstanding effectiveness and safety severely compromises the anti-cipated prognosis of ***(ALO)is a natural quinolizidine alkaloid with marked anti-cancer effects on multiple malignancies as well as favorable activity in relieving inflammation,allergies and ***,its therapeutic efficacy and underlying mechanism in CC are still *** the current study,MTT assay was employed to evaluate the viability of HeLa cells exposed to ALO to preliminarily estimate the effectiveness of ALO in ***,the effects of ALO on the proliferation and apoptosis of HeLa cells were further investigated by plate colony formation and flow cytometry,respectively,while the migration and invasion of ALO-treated HeLa cells were evaluated using Transwell ***,nude mice were subcutaneously inoculated with HeLa cells to demonstrate the anti-CC properties of ALO in *** molecular mechanisms underlying these effects of ALO were evaluated by Western blot and immunohistochemical *** study experimentally demonstrated that ALO inhibited the proliferation of HeLa cells via G2 phase cell cycle ***,ALO promoted an increase in the percentage of apoptotic HeLa cells by increasing the Bax/Bcl-2 ***,the migration and invasion of HeLa cells were attenuated by ALO treatment,which was considered to result from inhibition of epithelial-to-mesenchymal *** molecular mechanisms,the expression and activation of the IL-6-JAK1-STAT3 feedback loop were markedly suppressed by ALO *** study indicated that ALO markedly suppresses the proliferation,migration and invasion and enhances the apoptosis of HeLa *** addition,these prominent anti-CC properties of ALO are associated with repression of the IL-6-JAK1-STAT3 feedback loop.

关键词： Cervical cancer Chemotherapy Aloperine Epithelial-mesenchymal transition IL-6-JAK1-STAT3 feedback loop

Soil physicochemical properties and vegetation structure along an elevation gradient and implications for the response of alpine plant development to climate change on the northern slopes of the Qilian Mountains

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Journal of Mountain Science 2018年第5期15卷 1006-1019页

作者： yang yong-sheng ZHANG Li LI Hong-qin HE Hui-dan WEI Ya-xi LUO Jin ZHANG Guang-ru HUANG Yu-ru LI Ying-nian ZHOU Hua-kun The Key Laboratory of Restoration Ecology in Cold Region of Qinghai Province Northwest Institute of Plateau BiologyChinese Academy of Sciences Xining 810008 China Xining Institute of Surveying and Mapping Xining 810000 China Keg Laboratory of Adaptation and Evolution of Plateau Biota Northwest Institute of Plateau Biology Chinese Academy of Sciences Xining 810008 China University of Chinese Academy of Sciences Beijing 100049 China

Elevation is one of key factors to affect changes in the environment, particularly changes in conditions of light, water and heat. Studying the soil physicochemical properties and vegetation structure along an elevation gradient is important for understanding the responses of alpine plants andtheir growing environment to climate change. In this study, we studied plant coverage, plant height, species richness, soil water-holding capacity, soil organic carbon(SOC) and total nitrogen(N) on the northern slopes of the Qilian Mountains at elevations from2124 to 3665 m. The following conclusions were drawn:(1) With the increase of elevation, plant coverage and species richness first increased and then decreased, with the maximum values being at 3177 *** height was significantly and negatively correlated with elevation(r=–0.97, P<0.01), and the ratio of decrease with elevation was 0.82 cm·100 m-1.(2) Both soil water-holding capacity and soil porosity increased on the northern slopes of the Qilian Mountains with the increase of elevation. The soil saturated water content at the 0-40 cm depth first increased and then stabilized with a further increase of elevation, and the average ratio of increase was2.44 mm·100 m-1. With the increase of elevation, the average bulk density at the 0-40 cm depth first decreased and then stabilized at 0.89 g/cm3.(3) With the increase of elevation, the average SOC content at the 0-40 cm depths first increased and then decreased,and the average total N content at the 0-40 cm depth first increased and then stabilized. The correlation between average SOC content and average total N content reached significant level. According to the results of this study, the distribution of plants showed a mono-peak curve with increasing elevation on the northern slopes of the Qilian Mountains. The limiting factor for plant growth at the high elevation areas was not soil physicochemical properties, and therefore,global warming will likely facilitate the develo

关键词： Qilian Mountains Elevation Vegetationstructure Soil physicochemical properties Climatechange

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从引簋看周代的命卿制度

史学集刊 2015年第5期 109-118页

作者：杨永生东北师范大学历史文化学院吉林长春130024

山东高青陈庄出土的引簋,其器主引是周王所任命的齐国命卿。引获赐的彤弓、矢代表单次军事指挥权,也同重命制度有关,并不能说明引的身份是齐侯。周代设立命卿制度,是一种在国家范围内控制"武力的合法使用权"的重要举措。一方面辅助诸侯... 详细信息

山东高青陈庄出土的引簋,其器主引是周王所任命的齐国命卿。引获赐的彤弓、矢代表单次军事指挥权,也同重命制度有关,并不能说明引的身份是齐侯。周代设立命卿制度,是一种在国家范围内控制"武力的合法使用权"的重要举措。一方面辅助诸侯、增强方伯实力以便更好地藩屏周室;另一方面,命卿也是周王对诸侯进行监督、引导的重要手段;命卿制度的根本目的在于维系周的一统局面。从西周中期开始,王官开始出现"私臣化"趋势,在春秋之时,命卿成为诸侯之臣。命卿制度的这一变化,虽然同王权的衰落有关,但其主要原因是制度本身存在的缺陷。

关键词：引命卿弓矢赐予

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土层随机地震反应分析中侧向边界的影响分析

岩土力学 2011年第11期32卷 3442-3447页

作者：陈清军杨永胜同济大学土木工程防灾国家重点实验室上海200092

研究了随机地震激励下土层地震反应及土-结构相互作用分析中有限土域的取值范围对计算精度的影响。分别以基岩白噪声谱和杜修力修正基岩谱作为输入,进行了土层随机地震反应分析,探讨了自由边界、固定边界和黏弹性边界3种人工边界条件下... 详细信息

研究了随机地震激励下土层地震反应及土-结构相互作用分析中有限土域的取值范围对计算精度的影响。分别以基岩白噪声谱和杜修力修正基岩谱作为输入,进行了土层随机地震反应分析,探讨了自由边界、固定边界和黏弹性边界3种人工边界条件下土域的取值范围、土介质阻尼和土体长深比(L/H)对土层随机地震反应的影响,给出了侧向人工边界合理位置的具体建议。在此基础上,选取土体的合理边界范围,建立土-结构相互作用分析模型,分别以基岩白噪声谱、杜修力修正基岩谱以及实测地震波功率谱作为输入,进行了土-结构相互作用体系随机地震反应分析,计算结果验证了侧向人工边界取值在土-结构相互作用体系随机地震反应分析中的有效性。

关键词：随机地震激励土层随机地震反应土-结构相互作用侧向人工边界

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2105发动机捣缸原因分析

金属热处理 2005年第7期30卷 86-87页

作者：杨永生中国一拖集团有限公司工艺材料研究所河南洛阳471004

在2105发动机作整机磨合试验时发现,试验2h后,突然发生捣缸事故,发动机缸体被打出一个洞,拆开后发现第一缸连杆被打断、活塞和缸套受到撞击而破坏、两根连杆螺栓断裂.为了防止类似情况发生,对该发动机捣缸原因进行了分析.

关键词： 2105发动机捣缸现象连杆螺栓强度钢

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14例泛发性大疱性固定性药疹临床分析

临床皮肤科杂志 2022年第1期51卷 49-54页

作者：杨璐杨永生复旦大学附属华山医院皮肤科上海200040

目的:比较泛发性大疱性固定性药疹(GBFDE)与中毒性表皮坏死松解症(TEN)病例的临床表现、治疗方案及疾病转归情况,探索其临床特征。方法:对我科2008-2018年收住入院的14例GBFDE患者以及中毒性表皮坏死松解症病情严重程度评分(SCORTEN)相... 详细信息

目的:比较泛发性大疱性固定性药疹(GBFDE)与中毒性表皮坏死松解症(TEN)病例的临床表现、治疗方案及疾病转归情况,探索其临床特征。方法:对我科2008-2018年收住入院的14例GBFDE患者以及中毒性表皮坏死松解症病情严重程度评分(SCORTEN)相同、皮肤剥脱面积占体表面积百分比(total body surface area, TBSA)相近的TEN患者按照1∶3的数量比进行病例对照分析。结果:GBFDE与TEN常见的致敏药物主要有抗生素、抗癫痫药、非甾体类抗炎药,GBFDE患者在是否黏膜受累、≥2处黏膜受累、住院时间等方面均显著低于TEN患者(P分别为0.002,0.000,0.000)。GBFDE患者的糖皮质激素最大使用剂量、激素开始减量时间、减量前激素总量分别为0.9±0.3mg/kg·d、5.5(4.25,7)d、4.7(3.9,5.2)mg/kg,均少于TEN患者的1.4±0.3mg/kg·d、10(7,12)d、11.9(9.3,16.7)mg/kg·d(P均=0.000);治疗过程中3例GBFDE患者(21.4%)联合应用静脉输注免疫球蛋白(intravenous immunoglobulin, IVIG),少于TEN患者(37/52,88.1%,P=0.000)。电解质紊乱是GBFDE与TEN最常见的并发症,GBFDE患者电解质紊乱、药物性肝损伤、继发感染、消化道出血等并发症的发生率均明显低于TEN患者(P分别为0.000、0.047、0.004、0.026)。结论:尽管临床表现相似,但GBFDE临床转归较TEN好,需要的糖皮质激素量更小,因而糖皮质激素相关并发症的发生率较TEN低,临床上应注意避免过度治疗。

关键词：药疹,固定性,大疱性,泛发性史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症皮质激素 SCORTEN IVIG

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我国针对农村孤儿的社会政策变迁及调整对策

中国青年政治学院学报 2005年第6期24卷 132-136页

作者：杨生勇华中师范大学社会学系湖北武汉430079

建国以来,我国针对农村孤儿的社会政策经过了从救助制向福利制的转变过程,目前正在进行的农村税费改革给农村孤儿的社会政策变为完全福利制提供了有利的条件和机遇,但在社会转型期的调整过程中,需要我们从观念、制度、环境等方面进行全... 详细信息

建国以来,我国针对农村孤儿的社会政策经过了从救助制向福利制的转变过程,目前正在进行的农村税费改革给农村孤儿的社会政策变为完全福利制提供了有利的条件和机遇,但在社会转型期的调整过程中,需要我们从观念、制度、环境等方面进行全面的配套改革,才能推动农村孤儿完全福利制的实现。

关键词：农村孤儿社会政策变迁调整对策