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Chinese Journal of Mechanical Engineering 2007年第1期20卷 44-46页

作者： LI Xiaoquan DU Zeyu yang xuguang School of Matenals Science and Engineenng Tianjin University Tianjin 300072 China School of Mataials Science and Engineenng Jiangsu University of Science and Technology Zhenjiang 212003 China

For characteristics of open and far from thermodynamic equilibrium in welding chemical reaction, a new kind of quantitative method, which is used to analyze direction and extent for chemical reaction of SiO2/Fe during quasi-steady state period, is introduced with the concept of non-equilibrium stationary state. The main idea is based on thermodynamic driving forces, which result in non-zero thermodynamic fluxes and lead to chemical reaction far away from thermodynamic equilibrium. There exists certain dynamic equilibrium relationship between rates of diffusion fluxes in liquid phase of reactants or products and the rate equation of chemical reaction when welding is in quasi-steady state. As result of this, a group of non-linear equations containing concentrations of all substances at interface of slag/liquid-metal may be established. Moreover the stability of this non-equilibrium stationary state is discussed using dissipative structure theory and it is concluded theoretically that this non-equilibrium stationary state for welding chemical reaction is of stability.

关键词： Welding chemical metallurgy Non-equilibrium stationary state Dissipative structure Stability

Numerical and Experimental Study on Heat Transfer Characteristics of Single Vibrating Blade in a Channel Flow

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Journal of Thermal Science 2023年第3期32卷 982-992页

作者： HU Jinqi MIN Chunhua yang xuguang WANG Kun XIE Liyao School of Energy and Environmental Engineering Hebei University of TechnologyTianjin 300401China Hebei Key Laboratory of Thermal Science and Energy Clean Utilization Hebei University of TechnologyTianjin 300401China

The heat transfer characteristics of the vibrating blades of different shapes were numerically modeled in the present work.A single blade was arranged in a channel with vertical or horizontal *** the static environment and the channel flow were *** types of blades,rectangular,trapezoidal,serrated,and folding,were comparably *** results showed that the vibrating blade could effectively enhance the convection heat transfer of the heated surface with a smaller increase of pressure *** the static environment,the heat transfer performance of the vertical alignment of the blade is better than the horizontal *** channel flow,the opposite conclusion is *** the inlet velocity of channel flow v_(inlet)=2 m/s and v_(inlet)=6m/s,the maximum improvement of the local convection heat transfer coefficient is about 98%and 12%,*** corresponding pressure drops were reduced and increased by 9.5%and 8.8%,*** vibrating blade can effectively improve the convection heat transfer at lower inlet *** the same working conditions,the pressure drop difference between the four shapes of fan blades is less than 1%,and the folding blade has the best local heat dissipation performance.

关键词： convection heat transfer vibrating blade alignment of the blade shape of the blade

Coupled MRT Lattice Boltzmann Study of Electrokinetic Mixing of Power-Law Fluids in Microchannels with Heterogeneous Surface Potential

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Advances in Applied Mathematics and Mechanics 2018年第6期10卷 1478-1496页

作者： xuguang yang Lei Wang Baochang Shi School of Mathematics and Computational Science Hunan First Normal UniversityChangsha 410205HunanChina Department of Applied Mathematics The Hong Kong Polytechnic UniversityHung HomHong Kong School of Mathematics and Physics China University of GeosciencesWuhan430074HubeiChina School of Mathematics and Statistics Huazhong University of Science and TechnologyWuhan 430074HubeiChina

The electrokinetic mixing,as a powerful technique in microfluidic devices,is widely used in many *** this study,a more general dynamic model,which consists of Poisson equation,Nernst-Planck equation and Navier-Stokes equations,is used to describe the electrokinetic mixing of non-Newtonian fluids in ***,a coupled multiple-relaxation-time(MRT)lattice Boltzmann(LB)framework is developed to solve this complicated multi-physics transport *** numerical simulations,we mainly consider the effects of the arrangement of nonuniform surface potentials and the power-law index on the mixing efficiency and the volumetric flow *** results show that the mixing efficiency and the volumetric flow rate of shear-thinning fluids are higher than that of shear-thickening fluids under the same *** is also shown that for both types of fluids,there should be a balance between the mixing and liquid transport in electrokinetic microfluidics.

关键词： Lattice Boltzmann method electrokinetic mixing non-Newtonian fluids

Effects of gamma-aminobutyric acid A-receptor antagonist on sleep-wakefulness cycles following lesion to the ventrolateral preoptic area in rats

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Neural Regeneration Research 2009年第1期4卷 53-57页

作者： Xin Zhang Yina Sun Peng Xie xuguang yang Yiping Hou Laboratory of Neurobiology Department of Anatomy Histology and Embryology School of Basic Medical Sciences Lanzhou University Lanzhou 730000 Gansu Province China

BACKGROUND： Neurons expressing gamma-aminobutyric acid （GABA） play an important role in the regulation of wakefulness to sleep, as well as the maintenance of sleep. However, the role of GABAergic neurons in the tuberomammillary nucleus （TMn）, with regard to the sleep-wakefulness cycle, is poorly understood. OBJECTIVE： To investigate the effects of GABAergic neurons in the TMn on the sleep-wakefulness cycle. DESIGN, TIME AND SETTING： Randomized controlled study, performed at the Laboratory of Neurobiology, Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Lanzhou University from July 2007 to February 2008. MATERIALS： Fifteen healthy, adult, male, Sprague Dawley rats were randomly divided into three groups（n = 5）： control, ventrolateral preoptic area （VLPO） lesion, and VLPO lesion plus GABAA receptor antagonist-treated. Ibotenic acid and bicuculline were provided by Sigma （St. Louis, USA）. METHODS： Four electroencephalogram screw electrodes were implanted into the skull at a frontal region （two） and parietal bones （two） on each side. Three flexible electromyogram wire electrodes were placed into the nuchal muscles. On day 8, a fine glass micropipette （10–20 mm tip diameter） containing ibotenic acid solution （10 nmol/L） was injected into the VLPO in both hemispheres following bone wax removal under anesthesia. One week after the second surgery, sleep-wakefulness states were recorded in rats from the VLPO lesion group. On day 10 after VLPO lesion, bicuculline （10 nmol/L）, a GABAA-receptor antagonist, was microinjected into the TMn and sleep-wakefulness states were recorded for 24 hours. MAIN OUTCOME MEASURES： Duration of the sleep-wakefulness cycle in each group using a Data acquisition unit （Micro1 401 mk2） and Data collection software （Spike Ⅱ）. RESULTS： VLPO lesion induced an increased duration of wakefulness （W, 13.17%） and light slow-wave sleep （SWS1, 28.9%）, respectively. Deep slow-wave sleep （SWS2, 43.74%） and paradoxical

关键词： GABAergic neuron GABAA-receptor antagonist histaminergic neuron neurotoxiclesion tuberomammillary nucleus ventrolateral preoptic area

Histone post-translational modification and the DNA damage response

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Genes & Diseases 2023年第4期10卷 1429-1444页

作者： Haoyun Song Rong Shen Xiangwen Liu xuguang yang Kun Xie Zhao Guo Degui Wang School of Basic Medical Sciences Lanzhou UniversityLanzhouGansu 730000China

DNA is highly vulnerable to spontaneous and environmental timely damage in living *** damage may cause genetic instability and increase cancer risk if the damages are not repaired timely and *** cells possess several DNA damage response(DDR)mechanisms to protect the integrity of their *** of the mechanisms under-lying the DNA damage response following lethal damage will facilitate the identification of therapeutic targets for *** post-translational modifications(PTMs)have been indicated to play different roles in the repair of DNA *** this context,histone PTMs regulate recruitment of downstream effectors,and facilitate appropriate repair *** review outlines the current understanding of different histone PTMs in response to DNA dam-age repair,besides,enumerates the role of new type PTMs such as histone succinylation and crotonylation in regulating DNA damage repair processes.

关键词： DNA damage DNA damage response Histone Post-translational modifications(PTMs)

Chemerin aggravates DSS-induced colitis by suppressing M2 macrophage polarization

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Cellular & Molecular Immunology 2014年第4期11卷 355-366页

作者： Yuli Lin xuguang yang Wenjie Yue Xiaofei Xu Bingji Li Linlin Zou Rui He Department of Immunology School of Basic Medical Sciences Shanghai China Department of Gastroenterology Huashan Hospital Shanghai China Biotherapy Research Center Fudan University Shanghai China

Chemerin is present in various inflammatory sites and is closely involved in tissue inflammation. Recent studies have demonstrated that chemerin treatment can cause either anti-inflammatory or pro-inflammatory effects according to the disease model being investigated. Elevated circulating chemerin was recently found in patients with inflammatory bowel disease （IBD）; however, the role of chemerin in intestinal inflammation remains unknown. In this study, we demonstrated that the administration of exogenous chemerin （aa 17-156） aggravated the severity of dextran sulfate sodium （DSS）-induced colitis, which was characterized by higher clinical scores, extensive mucosal damage and significantly increased local and systemic production of pro-inflammatory cytokines, including IL-6, TNF-a and interferon （IFN-7）. Interestingly, chemerin did not appear to influence the magnitudes of inflammatory infiltrates in the colons, but did result in significantly decreased colonic expression of M2 macrophage-associated genes, including Arginase 1 （Arg-1）, Yml, FIZZ1 and IL-IO, following DSS exposure, suggesting an impaired M2 macrophage skewing in vivo. Furthermore, an in vitro experiment showed that the addition of chemerin directly suppressed M2 macrophage-associated gene expression and STAT6 phosphorylation in IL-4-stimulated macrophages. Significantly elevated chemerin levels were found in colons from DSS-exposed mice and from ulcerative colitis （UC） patients and appeared to positively correlate with disease severity. Moreover, the in vivo administration of neutralizing anti-chemerin antibody significantly improved intestinal inflammation following DSS exposure. Taken together, our findings reveal a pro-inflammatory role for chemerin in DSS-induced colitis and the ability of chemerin to suppress the anti-inflammatory M2 macrophage response. Our study also suggests that upregulated chemerin in inflamed colons may contribute to the pathogenesis of IBD.

关键词： chemerin intestinal inflammation macrophage

Curative effect of acupuncture and moxibustion on insomnia: a randomized clinical trial

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Journal of Traditional Chinese Medicine 2013年第4期33卷 428-432页

作者： Xiyan Gao Cuixiang Xu Peiyu Wang Shan Ren Yanli Zhou xuguang yang Ling Gao College of Acupuncture and Massage Henan University of Traditional Chinese Medicine

OBJECTIVE: To observe the effect of acupuncture and moxibustion on insomnia and explore its mechanism. METHODS: One hundred and twenty patients were randomly divided into an experiment group and a control group. Sixty patients in the experiment group were treated once a day with acupuncture at Baihui (GV 20), Sishencong (EX-HN 1), Shenmai (BL 62), and Zhaohai (KI 6) and with moxibustion at Baihui (GV 20) and Sishencong (EX-HN 1). Sixty patients in the control group were acupunctured once a day at Shenmen (HT 7), Neiguan (PC 6), and Sanyinjiao (SP 6).The Pittsburgh Sleep Quality Index (PSQI) was used to compare sleep improvement between the two groups. RESULTS: The total effective rate was 87.7% in the experiment group and 76.3% in the control group. The PSQI scores and the total score were lower after treatment than before treatment in bothgroups. However, the reduction in the experiment group was greater than that in the control group in sleeping quality, time to fall asleep, sleeping disorder, and daytime function (P<0.05). CONCLUSION: Acupuncture and moxibustion at Baihui (GV 20), Sishencong (EX-HN 1), Shenmai (BL 62), and Zhaohai (KI 6) significantly improved insomnia symptoms in the experiment group compared with the control group.

关键词： Acupuncture Sleep initiation and maintenance disorders Treatment outcome Randomized clinical trialsc

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磁州窑瓷枕纹饰的吉祥寓意研究

中国陶瓷 2019年第6期55卷 91-95页

作者：杨旭光河北环境工程学院

磁州窑的历史可追溯到北齐和隋唐时代,是我国北方著名的民间瓷窑。其生产的瓷器,除少量的贡品瓷,绝大多数是面向普通中、下层大众日常使用的盘、碗、壶、罐、枕、炉、瓦饰等。其中瓷枕的生产量仅次于盘和碗,瓷枕因其喜闻乐见的装饰和生... 详细信息

磁州窑的历史可追溯到北齐和隋唐时代,是我国北方著名的民间瓷窑。其生产的瓷器,除少量的贡品瓷,绝大多数是面向普通中、下层大众日常使用的盘、碗、壶、罐、枕、炉、瓦饰等。其中瓷枕的生产量仅次于盘和碗,瓷枕因其喜闻乐见的装饰和生活实用性而备受广大民众欢迎,瓷枕纹饰的题材与寓意为制作者提供了广阔的想象力,人们把现实生活中的富贵、吉祥等美好愿望直观朴实的表达在瓷枕纹饰中,这些纹饰就是磁州窑百姓的美好梦想和情感寄托。通过对磁州窑瓷枕吉祥纹饰的分类研究,论述了这些纹饰的寓意和存在的价值。

关键词：磁州窑瓷枕纹饰吉祥寓意

Bi_2S_3-BiOCl/煤矸石复合光催化剂的制备及光催化性能

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复合材料学报 2017年第8期34卷 1847-1852页

作者：李燕杨旭光曹林林安徽建筑大学材料与化学工程学院合肥230601

以表面改性煤矸石粉、Bi(NO_3)_3·5H_2O和NH_4Cl为原料,采用超声化学法制备了BiOCl/煤矸石前驱体;并通过BiOCl/煤矸石前驱体和硫代乙酰胺(TAA)的阴离子交换反应,原位制备了Bi_2S_3-BiOCl/煤矸石复合光催化剂。利用XRD和SEM对Bi_2S_3-Bi... 详细信息

以表面改性煤矸石粉、Bi(NO_3)_3·5H_2O和NH_4Cl为原料,采用超声化学法制备了BiOCl/煤矸石前驱体;并通过BiOCl/煤矸石前驱体和硫代乙酰胺(TAA)的阴离子交换反应,原位制备了Bi_2S_3-BiOCl/煤矸石复合光催化剂。利用XRD和SEM对Bi_2S_3-BiOCl/煤矸石复合光催化材料的结构及表面形貌进行了表征,并以可见光为光源,甲基橙为目标降解物,对其光催化活性进行了研究。结果表明:在可见光辐照下,Bi_2S_3-BiOCl/煤矸石复合光催化剂表现出较高的光催化降解能力,这是由于Bi_2S_3与BiOCl复合后形成的异质结促进了光生电子和光生空穴的分离,抑制了它们的复合。

关键词：声化学法阴离子交换 BiOCl Bi2S3 煤矸石光催化性能

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骨质瓷壁饰在现代家居环境中的应用研究

中国陶瓷 2018年第8期54卷 85-89页

作者：杨旭光河北环境工程学院

随着人们生活品位的提高,壁饰成为营造个性化家居空间的首选。壁饰是一种古老的装饰艺术,是＂壁＂与＂饰＂的结合,壁饰的材料更是多种多样。骨质瓷是目前陶瓷界公认的高档瓷种,骨质瓷应用于家居壁饰,在当今是一个新的研究课题。通过对... 详细信息

随着人们生活品位的提高,壁饰成为营造个性化家居空间的首选。壁饰是一种古老的装饰艺术,是＂壁＂与＂饰＂的结合,壁饰的材料更是多种多样。骨质瓷是目前陶瓷界公认的高档瓷种,骨质瓷应用于家居壁饰,在当今是一个新的研究课题。通过对骨质瓷壁饰在家居环境中的应用研究,论述了骨质瓷壁饰独特的艺术效果和广阔的应用前景。

关键词：骨质瓷家居环境壁饰应用艺术语言