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Vector Radiative Transfer in a Vertically Inhomogeneous Scattering and Emitting ***Ⅰ:A New Discrete Ordinate Method

Journal of Meteorological Research 2024年第2期38卷 209-224页

作者： Ziqiang ZHU Fuzhong WENG yang han Chinese Academy of Meteorological Sciences China Meteorological AdministrationBeijing 100081 University of Chinese Academy of Sciences Beijing 100049 CMA Earth System Modeling and Prediction Centre China Meteorological Administration(CMA)Beijing 100081 State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesChina Meteorological AdministrationBeijing 100081

The original vector discrete ordinate radiative transfer(VDISORT)model takes into account Stokes radiance vector but derives its solution assuming azimuthal symmetric surface reflective matrix and atmospheric scattering phase matrix,such as the phase matrix derived from spherical particles or randomly oriented non-spherical *** this study,a new VDISORT is developed for general atmospheric scattering and boundary *** vector is decomposed into both sinusoidal and cosinusoidal harmonic modes,and the radiance at arbitrary viewing geometry is solved directly by adding two zero-weighted points in the Gaussian quadrature *** complex eigenvalues in homogeneous solutions are also taken into full *** accuracy of VDISORT model is comprehensively validated by four cases:Rayleigh scattering case,the spherical particle scattering case with the Legendre expansion coefficients of 0th-13th orders of the phase matrix(hereinafter L13),L13 with a polarized source,and the randomoriented oblate particle scattering case with the Legendre expansion coefficients of 0th-11th orders of the phase matrix(hereinafter L11).In all cases,the simulated radiances agree well with the benchmarks,with absolute biases less than 0.0065,0.0006,and 0.0008 for Rayleigh,unpolarized L13,and L11,*** a polarized bidirectional reflection distribution function(pBRDF)matrix is used as the lower boundary condition,VDISORT is now able to handle fully coupled atmospheric and surface polarimetric radiative transfer processes.

关键词： radiative transfer discrete ordinate polarization Stokes vector vector discrete ordinate radiative transfer(VDISORT)

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Impact of Atmospheric Transmittance and NLTE Correction on Simulation of High Spectral Infrared Atmospheric Sounder onboard FY-3E

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Journal of Meteorological Research 2024年第2期38卷 225-234页

作者： Chenggege FANG Peiming DONG yang han Wanlin KAN Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Key Laboratory for Aerosol-Cloud-Precipitation of China Meteorological AdministrationNanjing University of Information Science&TechnologyNanjing 210044 Donghai Laboratory Zhoushan 316021 State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesChina Meteorological AdministrationBeijing 100081 CMA Earth System Modeling and Prediction Centre China Meteorological Administration(CMA)Beijing 100081 Key Laboratory of Transportation Meteorology of China Meteorological Administration Nanjing Joint Institute for Atmospheric SciencesNanjing 210041

With the launch of the first civilian early-morning orbit satellite Fengyun-3E(FY-3E),higher demands are placed on the accuracy of radiative transfer simulations for hyperspectral infrared ***,several key issues are investigated in the ***,the accuracy of the fast atmospheric transmittance model implemented in the Advanced Research and Modeling System(ARMS)has been evaluated with both the line-by-line radiative transfer model(LBLRTM)and the actual satellite *** results indicate that the biases are generally less than 0.25 K when compared to the LBLRTM,while below 1.0 K for the majority of the channels when compared to the ***,during both comparisons,significant biases are observed in certain *** accuracy of Hyperspectral Infrared Atmospheric Sounder-II(HIRAS-II)onboard FY-3E is comparable to,and even superior to that of the Cross-track Infrared Sounder(CrIS)onboard ***,apodization is a crucial step in the processing of hyperspectral data in that the apodization function is utilized as the instrument channel spectral response function to produce the satellite channel-averaged *** further explore the difference between the apodized and unapodized simulations,Sinc function is adopted in the fast transmittance *** is found that the use of Sinc function can make the simulations fit the original satellite observations *** simulating with apodized observations,the use of Sinc function exhibits larger deviations compared to the Hamming ***,a correction module is applied to minimize the impact of Non-Local Thermodynamic Equilibrium(NLTE)in the shortwave infrared *** is verified that the implementation of the NLTE correction model leads to a significant reduction in the bias between the simulation and observation for this band.

关键词： high spectral infrared sounding atmospheric transmittance apodization Non-Local Thermodynamic Equilibrium Fengyun-3E(FY-3E)

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Polymer: Non-fullerene acceptor heterojunction-based phototransistor for short-wave infrared photodetection

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Nano Research 2024年第4期17卷 3087-3095页

作者： Jing Li Weigang Zhu yang han Yanhou Geng Wenping Hu Key Laboratory of Organic Integrated Circuits of Ministry of Education&Key Laboratory of Molecular Optoelectronic Sciences School of Science&Collaborative Innovation Center of Chemical Science and Engineering(Tianjin)Tianjin UniversityTianjin 300072China Key Laboratory of Organic Integrated Circuits of Ministry of Education&Key Laboratory of Molecular Optoelectronic Sciences School of Materials Science and EngineeringTianjin UniversityTianjin 300072China

It remains full of challenge for extending short-wave infrared(SWIR)spectral response and weak-light detection in the context of broad spectral responses for *** this work,a novel poly(2,5-bis(4-hexyldodecyl)-2,5-dihydro-3,6-di-2-thienyl-pyrrolo[3,4-c]pyrrole-1,4-dione-alt-thiophene)(PDPPT3-HDO):COTIC-4F organic bulk-heterojunction is prepared as active layer for bulk heterojunction ***3-HDO serves as a hole transport material,while COTIC-4F enhances the absorption of SWIR light to 1020 *** a result,smooth and connected PDPPT3-HDO film is fabricated by blade coating method and exhibits high hole mobility up to 2.34 cm^(2)·V^(-1)·s^(-1) with a current on/off ratio of 4.72×10^(5) in organic thin film ***3-HDO:COTIC-4F heterojunction phototransistors exhibit high responsivity of 2680 A·W^(-1) to 900 nm and 815 A·W^(-1) to 1020 nm,with fast response time(rise time~20 ms and fall time~100 ms).The photosensitivity of the heterojunction phototransistor improves as the mass ratio of non-fullerene acceptors increases,resulting in an approximately two orders of magnitude enhancement compared to the bare polymer ***,the phototransistor exhibits decent responsivity even under ultra-weak light power of 43μW·cm^(-2) to 1020 *** work represents a highly effective and general strategy for fabricating efficient and sensitive SWIR light photodetectors.

关键词： photodetection phototransistor organic semiconductor heterojunction non-fullerene acceptor

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Dynamic simulation analysis of molten salt reactor-coupled air-steam combined cycle power generation system

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Nuclear Science and Techniques 2024年第2期35卷 222-233页

作者： Jing-Lei Huang Guo-Bin Jia Li-Feng han Wen-Qian Liu Li Huang Zheng-han yang Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China

A nonlinear dynamic simulation model based on coordinated control of speed and flow rate for the molten salt reactor and combined cycle systems is proposed here to ensure the coordination and stability between the molten salt reactor and power *** model considers the impact of thermal properties of fluid variation on accuracy and has been validated with *** study reveals the capability of the control system to compensate for anomalous situations and maintain shaft stability in the event of perturbations occurring in high-temperature molten salt tank outlet ***,the control system’s impact on the system’s dynamic characteristics under molten salt disturbance is also *** results reveal that after the disturbance occurs,the controlled system benefits from the action of the control,and the overshoot and disturbance amplitude are positively correlated,while the system power and frequency eventually return to the initial *** simulation model provides a basis for utilizing molten salt reactors for power generation and maintaining grid stability.

关键词： Molten salt reactor Combined cycle Dynamic characteristic Control

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Protein lysine crotonylation in cellular processions and disease associations

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Genes & Diseases 2024年第5期11卷 219-235页

作者： Hongling Zhao yang han Pingkun Zhou Hua Guan Shanshan Gao Beijing Key Laboratory for Radiobiology Beijing Institute of Radiation MedicineBeijing 100850China

Protein lysine crotonylation(Kcr)is one conserved form of posttranslational modifications of proteins,which plays an important role in a series of cellular physiological and pathological *** e-amino groups are the primary sites of such modification,resulting in four-carbon planar lysine crotonylation that is structurally and functionally distinct from the acetylation of these *** levels of Kcr modifications have been identified on both histone and non-histone *** present review offers an update on the research progression regarding protein Kcr modifications in biomedical contexts and provides a discussion of the mechanisms whereby Kcr modification governs a range of biological *** addition,given the importance of protein Kcr modification in disease onset and progression,the potential viability of Kcr regulators as therapeutic targets is elucidated.

关键词： Cell biology Disease Lysine crotonylation Posttranslational modification Therapeutic target

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Genome-edited rabbits:Unleashing the potential of a promising experimental animal model across diverse diseases

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Zoological Research 2024年第2期45卷 253-262页

作者： yang han Jiale Zhou Renquan Zhang Yuru Liang Liangxue Lai Zhanjun Li Key Laboratory of Zoonosis Research Ministry of EducationCollege of Animal ScienceJilin UniversityChangchunJilin 130062China CAS Key Laboratory of Regenerative Biology Guangdong Provincial Key Laboratory of Stem Cell and Regenerative MedicineSouth China Institute for Stem Cell Biology and Regenerative MedicineGuangzhou Institutes of Biomedicine and HealthChinese Academy of SciencesGuangzhouGuangdong 510530China Guangzhou Regenerative Medicine and Health Guang Dong Laboratory(GRMH-GDL) GuangzhouGuangdong 510005China Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijing 100101China

Animal models are extensively used in all aspects of biomedical research,with substantial contributions to our understanding of diseases,the development of pharmaceuticals,and the exploration of gene *** field of genome modification in rabbits has progressed ***,recent advancements,particularly in CRISPR/Cas9-related technologies,have catalyzed the successful development of various genome-edited rabbit models to mimic diverse diseases,including cardiovascular disorders,immunodeficiencies,agingrelated ailments,neurological diseases,and ophthalmic *** models hold great promise in advancing biomedical research due to their closer physiological and biochemical resemblance to humans compared to *** review aims to summarize the novel gene-editing approaches currently available for rabbits and present the applications and prospects of such models in biomedicine,underscoring their impact and future potential in translational medicine.

关键词： Genome editing Animal model Rabbit CRISPR/Cas9 Genetic diseases

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Non-invasive imaging of pathological scars using a portable handheld two-photon microscope

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Chinese Medical Journal 2024年第3期137卷 329-337页

作者： yang han Yuxuan Sun Feili yang Qingwu Liu Wenmin Fei Wenzhuo Qiu Junjie Wang Linshuang Li Xuejun Zhang Aimin Wang Yong Cui Graduate School Chinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100730China Department of Dermatology China-Japan Friendship HospitalBeijing 100029China College of Engineering Peking UniversityBeijing 100871China School of Chemical Biology and Biotechnology State Key Laboratory of Chemical OncogenomicsPeking University Shenzhen Graduate SchoolShenzhenGuangdong 518055China Department of Dermatology The First Affiliated Hospital of Nanchang UniversityNanchangJiangxi 330006China Academy for Advanced Interdisciplinary Studies Peking UniversityBeijing 100871China College of Future Technology Peking UniversityBeijing 100871China Beijing Transcend Vivoscope Biotech Beijing 100085China Department of Dermatology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui 230001China Institute of Dermatology Anhui Medical UniversityHefeiAnhui 230001China School of Electronics Peking UniversityBeijing 100871China

Background:Pathological scars are a disorder that can lead to various cosmetic,psychological,and functional problems,and no effective assessment methods are currently *** and treatment of pathological scars are based on cutaneous manifestations.A two-photon microscope(TPM)with the potential for real-time non-invasive assessment may help determine the under-surface pathophysiological conditions in *** study used a portable handheld TPM to image epidermal cells and dermal collagen structures in pathological scars and normal skin in vivo to evaluate the effectiveness of treatment in scar ***:Fifteen patients with pathological scars and three healthy controls were *** was performed using a portable handheld *** indexes were extracted from two dimensional(2D)and three dimensional(3D)perspectives,including collagen depth,dermo-epidermal junction(DEJ)contour ratio,thickness,orientation,and occupation(proportion of collagen fibers in the field of view)of *** depth-dependent indexes were computed through the 3D second harmonic generation image and three morphology-related indexes from the 2D *** assessed index differences between scar and normal skin and changes before and after ***:Pathological scars and normal skin differed markedly regarding the epidermal morphological structure and the spectral characteristics of collagen *** indexes were employed to distinguish between normal skin and scar *** significant differences were found in average depth(t=9.917,Phandheld TPM can distinguish collagen from skin tissues;thus,it is more suitable for scar imaging than reflectance confocal ***,a TPM may be an auxiliary tool for scar treatment selection and assessing treatment efficacy.

关键词： Scars Two-photon microscope Two-photon excitation fluorescence Second harmonic generation microscopy

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Scutellarein Ameliorated Chondrocyte Inflammation and Osteoarthritis in Rats

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Current Medical Science 2024年第2期44卷 355-368页

作者： Shao-ze JING Shu-han yang Yun-kun QU Hai-hu HAO Hua WU Department of Orthopedics Third Hospital of Shanxi Medical UniversityShanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalTaiyuan 030032China Department of Orthopedics Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Objective:Osteoarthritis(OA)is a degenerative joint disorder characterized by the gradual degradation of joint cartilage and local *** study aimed to investigate the anti-OA effect of scutellarein(SCU),a single-unit flavonoid compound obtained from Scutellaria barbata ***,in ***:The extracted rat chondrocytes were treated with SCU and IL-1β.The chondrocytes were divided into control group,IL-1βgroup,IL-1β+SCU 50µmol/L group,and IL-1β+SCU 100µmol/L *** of rat chondrocytes was observed by toluidine blue and safranin O ***-8 method was used to detect the cytotoxicity of ***,qRT-PCR,Western blotting,immunofluorescence,SAβ-gal staining,flow cytometry,and bioinformatics analysis were applied to evaluate the effect of SCU on rat chondrocytes under IL-1β***,anterior cruciate ligament transection(ACL-T)was used to establish a rat OA *** changes were detected by safranin O/fast green,hematoxylin-eosin(HE)staining,and ***:SCU protected cartilage and exhibited anti-inflammatory effects via multiple ***,it could enhance the synthesis of extracellular matrix in cartilage cells and inhibit its *** addition,SCU partially inhibited the nuclear factor kappa-B/mitogen-activated protein kinase(NF-κB/MAPK)pathway,thereby reducing inflammatory cytokine production in the joint ***,SCU significantly reduced IL-1β-induced apoptosis and senescence in rat chondrocytes,further highlighting its potential role in OA *** vivo experiments revealed that SCU(at a dose of 50 mg/kg)administered for 2 months could significantly delay the progression of cartilage damage,which was reflected in a lower Osteoarthritis Research Society International(OARSI)score,and reduced expression of matrix metalloproteinase 13(MMP13)in ***:SCU is effective in the therapeutic management of OA and could serve as a potential candidate f

关键词： scutellarein osteoarthritis apoptosis mitogen-activated protein kinase(MAPK) nuclear factor kappa-B(NF-κB)

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Interface engineering of Co_(9)S_(8)/SnS heterostructure as a high-performance anode for lithium/sodium-ion batteries

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Rare Metals 2024年第2期43卷 612-623页

作者： Jia Luo Shi-Li Xiang Dan-yang han An Liu João Cunha Gang-Yong Li Zhao-Hui Hou Hong Yin School of Chemistry and Chemical Engineering Key Laboratory of Hunan Province for Advanced Carbon-based Functional MaterialsHunan Institute of Science and TechnologyYueyang414006China Hubei Jiufengshan Laboratory Wuhan430206China International Iberian Nanotechnology Laboratory(INL) Av.Mestre Jose Veiga4715-330BragaPortugal

Transition metal sulfide(TMS)anodes exhibit the characteristics of phase stability and high capacity for lithium/sodium-ion batteries(LIBs/SIBs).However,the TMS anodes often suffer from poor electronic conductivity,low ionic diffusion and large volume expansion during Li/Na-ion intercalation significantly impairing the Li/Na-storage ***,a long chain heterostructure composed of the Co_(9)S_(8) and SnS are first reported,which can generate rich phase interfaces,and small crystal *** unique structure can facilitate the properties of reactivity,conductivity and ionic *** addition,the heterostructure surface is modified by the N-doped carbon(N-DC@(CoSn)S),successfully improving the structural *** synergistic effects of Co_(9)S_(8)/SnS heterostructure and coated carbon layer effectively increase the capacity and cycling *** N-DC@(CoSn)S anode delivers enhanced high specific capacities of 820.6 mAh·g^(−1) at 1.0 A·g^(–1) after 500 cycles for LIBs and 339.2 mAh·g^(–1)at 0.5 A·g^(–1) after 1000 cycles for SIBs,*** work is expected to provide a material design idea for preparing LIBs/SIBs with high capacity and long cycling life.

关键词： Interface engineering Long chain heterostructure High capacity Cycling stability Li Na-ion batteries

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Mechanical properties and energy evolution of Beishan shallow-layer granite under different unloading paths

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Journal of Mountain Science 2024年第5期21卷 1728-1744页

作者： WANG Chuanle LI Erbing ZhanG Dengke han yang LU Hui HE Kang DU Guangyin School of Transportation Southeast UniversityNanjing 211189China College of Defense Engineering Army Engineering University of PLANanjing 210007China Nanjing Urban Construction Management Group Co. Ltd.Nanjing 210006China College of Field Engineering Army Engineering University of PLANanjing 210007China

Rock has mechanical characteristics and a fracture damage mechanism that are closely related to its loading history and loading path. The mechanical properties, fracture damage features, acoustic emission(AE) characteristics, and strain energy evolution of the Beishan shallow-layer granite used in triaxial unloading tests were investigated in this study. Three groups of triaxial tests, namely, conventional triaxial compression test(Group Ⅰ), maintaining deviatoric stress synchronously unloading confining pressure test(Group Ⅱ), and loading axial pressure synchronously unloading confining pressure test(Group Ⅲ), were carried out for the cylindrical granite specimens. AE monitoring device was utilized in these tests to determine the degree to which the AE waves and AE events reflected the degree of rock damage. In addition, the crack stress thresholds of the specimens were determined by volumetric strain method and AE parameter method, and strain energy evolution of the rock was explored in different damage stages. The results show that the shallow-layer granite experiences brittle failure during the triaxial loading test and unloading test, and the rock has a greater damage degree during the unloading test. The crack stress thresholds of these samples vary greatly between tests, but the threshold ratios of all samples are similar in the same crack damage stage. The Mogi-Coulomb strength criterion can better describe the unloading failure strength of the rock. The evolution of the AE parameter characteristics and strain energy differs between the specimens used in different stress path tests. The dissipative strain energy is the largest in Group Ⅱ and the smallest in Group Ⅰ.

关键词： Beishan granite Unloading test Mechanical properties Damage mechanism Acoustic emission Strain energy

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