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Genomic Surveillance for SARS-CoV-2 Variants: Dominance of XBB Replacement — China, January–June 2023

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China CDC weekly 2024年第15期6卷 324-331页

作者： Yenan feng Qiudong Su Lili Li xiaozhou He Peihua Niu xiaojuan Guo xiang Zhao Jing Tang Zhiyuan Jia Ji Wang Changcheng Wu Baicheng xia Zhixiao Chen Yuchao Wu Jing yang Songqi Chen Cao Chen Shiwen Wang xiaoping Dong National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina NHC Key Laboratory of Medical Virology and Viral Diseases National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina

Introduction:In the first half of 2023,a global shift was observed towards the predominance of XBB *** faced a significant epidemic between late 2022 and early 2023 due to Omicron subvariants BA.5.2 and *** study aims to depict the evolving variant distribution among provincial-level administrative divisions(PLADs)in China and explore the factors driving the predominance of XBB ***:Sequences from local and imported coronavirus disease 2019(COVID-19)cases recorded between January 1 and June 30,2023,were *** study analyzed the changing distribution of viral variants and assessed how the prior dominance of specific variants,XBB subvariants,and imported cases influenced the prevalence of the XBB replacement ***:A total of 56,486 sequences were obtained from local cases,and 8,669 sequences were from imported *** in April,there was a shift in the prevalence of XBB from imported to local cases,with varying dominance among *** PLADs previously high in BF.7,the rise of XBB was delayed.A positive correlation was found between XBB proportions in imported cases from January to March and local cases in *** distribution pattern of XBB subvariants differed between local and imported cases within the same *** significant differences were noted in the replacement rates of XBB ***:The timing of XBB dominance differed among various PLADs in China in the first half of 2023,correlating closely with the prevalence of XBB variants among imported cases.

关键词： dominance imported distribution

Recent Advances in Electrochemical-Based Silicon Production Technologies with Reduced Carbon Emission

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Research 2024年第1期2023卷 209-236页

作者： feng Tian Zhongya Pang Shen Hu Xueqiang Zhang Fei Wang Wei Nie Xuewen xia Guangshi Li Hsien-Yi Hsu Qian Xu Xingli Zou Li Ji Xionggang Lu State Key Laboratory of Advanced Special Steel&Shanghai Key Laboratory of Advanced Ferrometallurgy&School of Materials Science and Engineering Shanghai University99#Shangda RoadShanghai 200444China Center for Hydrogen Metallurgy Technology Shanghai UniversityShanghai 200444China State Key Laboratory of ASIC and System School of MicroelectronicsFudan University220#Handan RoadShanghai 200433China School of Energy and Environment Department of Materials Science and EngineeringCity University of Hong KongKowloon TongHong KongChina

Sustainable and low-carbon-emission silicon production is currently one of the main focuses for the metallurgical and materials science ***,considered a promising strategy,has been explored to produce silicon due to prominent advantages:(a)high electricity utilization efficiency;(b)low-cost silica as a raw material;and(c)tunable morphologies and structures,including films,nanowires,and *** review begins with a summary of early research on the extraction of silicon by *** has been placed on the electro-deoxidation and dissolution–electrodeposition of silica in chloride molten salts since the 21st century,including the basic reaction mechanisms,the fabrication of photoactive Si films for solar cells,the design and production of nanoSi and various silicon components for energy conversion,as well as storage ***,the feasibility of silicon electrodeposition in room-temperature ionic liquids and its unique opportunities are *** this basis,the challenges and future research directions for silicon electrochemical production strategies are proposed and discussed,which are essential to achieve large-scale sustainable production of silicon by electrochemistry.

关键词： directions electrodeposition electricity

One-step controlled electrodeposition nickel sulfides heterointerfaces favoring the desorption of hydroxyl groups for efficient hydrogen generation

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Rare Metals 2024年第9期43卷 4377-4386页

作者： Ru-Chun Li Xin-Yue Zhang Ze-Yue Qu feng-Yi Liu Quan-Qing Xu Zhao-xia Hu Jing-Wei Li Mohamed-Nawfal Ghazzal Jin-Li Yu Faculty of Chemistry and Chemical Engineering Yunnan Normal UniversityKunming 650500China Foshan Gaoke Hechuang Technology Co. Ltd.Foshan 528200China School of Chemistry and Chemical Engineering Guangzhou UniversityGuangzhou 510006China Universite Paris-Saclay UMR 8000 CNRSInstitut de Chimie PhysiqueOrsay 91405France Department of Chemistry City University of Hong KongHong Kong 999077China

The heterointerface engineering involving different components or phases represents a desirable strategy for enhancing the sluggish kinetics of hydrogen evolution reaction(HER).However,constructing desired heterointerfaces and elucidating the reaction mechanisms on the interface remains a considerable *** this work,we propose a straightforward electrochemical synthesis strategy to prepare the nickel sulfide-based heterointerfaces for *** mechanism of electrochemical synthesis is revealed,wherein metal-thiourea species can be formed at the cathode potential and subsequently oxidized to nickel sulfides at the anode *** this mechanism,a range of nickel sulfides,including NiS,Ni_(3)S_(2)/NiS,Ni/Ni_(3)S_(2)and Ni_(3)S_(2),have been successfully synthesized by tuning the potential range of cyclic *** these,the obtained Ni_(3)S_(2)/NiS@CC(CC:carbon cloth)exhibits the smallest overpotential of84 mV at 10 mA·cm^(-2)and high *** calculations further reveal that the combination of NiS and Ni_(3)S_(2)induces electron redistribution at the interface,and thus the Volmer process is effectively promoted with faster water dissociation and OH desorption ***,the simplicity method coupled with a clear synthesis mechanism and outstanding HER performance highlights its promising potential for practical applications.

关键词： Hydrogen evolution reaction Heterointerfaces OH desorption kinetics Electrochemical synthesis

ZIF-8-functionalized polymer electrolyte with enhanced performance for high-temperature solid-state lithium metal batteries

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Rare Metals 2024年第3期43卷 984-994页

作者： Jin-Fang Zhang Yuan-Yuan Wang xiao-feng Li Gen-Yan Zhang Ying Li Rong Liu Sheng-Liang Hu Tuo-Ping Hu Ruth Knibbe Qing-Bing xia School of Materials Science and Engineering North University of ChinaTaiyuan030051China School of Energy and Power Engineering North University of ChinaTaiyuan030051China School of Chemistry and Chemical Engineering North University of ChinaTaiyuan030051China School of Mechanical and Mining Engineering The University of QueenslandBrisbaneQLD4072Australia

Solid polymer electrolytes(SPEs)with high ionic conductivity are desirable for solid-state lithium metal batteries(SSLMBs)to achieve enhanced safety and energy *** nanofillers into a polymeric matrix to develop nanocomposite solid electrolytes(NCSEs)has become a promising method for improving the ionic conductivity of the ***,a novel ZIF-8-functionalized NCSE was prepared for high-temperature S SLMB s using an in situ radical polymerization *** is found that the ZIF-8 nanoparticles could reduce the crystallinity of polymer segments and offer a Lewis acid surface that promotes the dissociation of lithium bis(trifluoromethanesulfonyl)imide(LiTFSI)and stabilizes the TFSI^(-) anion ***,the as-prepared NCSE exhibits an outstanding ionic conductivity of 1.63×10^(-3)S·cm^(-1),an electrochem ical stability window of 5.0 V at 80℃,and excellent interface compatibility with lithium metal anode with a stable polarization over 2000 ***,the assembled SSLMBs with LiFePO_(4)cathode show dendrite-free Li-metal surface,good rate capability,and stable cycling stability with a capacity retention of 70%over 1000 cycles at a high temperature of 80℃.This work provides valuable insights into promoting the ionic conductivity of SPEs.

关键词： Lithium metal batteries Metal-organic frameworks Solid polymer electrolytes Lithium metal anode Interfacial compatibility

Application of dezocine patient-controlled epidural analgesia in postoperative analgesia in patients with total myomectomy

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World Journal of Clinical Cases 2024年第20期12卷 4265-4271页

作者： feng-feng Ning Ting-Ting Yao xiao-xia Wang Department of Anesthesiology Gansu Provincial Maternity and Child-care HospitalLanzhou 730050Gansu ProvinceChina Department of Gynecology Gansu Provincial Maternity and Child-Care HospitalLanzhou 730050Gansu ProvinceChina

BACKGROUND Uterine fibroids are common benign gynecological *** who experience excessive menstruation,anemia,and pressure symptoms should be administered medication,and severe cases require a total *** procedure is invasive and causes severe postoperative pain,which can affect the patient’s postoperative sleep quality and,thus,the recovery *** To evaluate use of dezocine in patient-controlled epidural analgesia(PCEA)for postoperative pain management in patients undergoing total *** We selected 100 patients undergoing total abdominal hysterectomy for uterine fibroids and randomized them into two groups:A control group receiving 0.2%ropivacaine plus 0.06 mg/mL of morphine and an observation group receiving 0.2%ropivacaine plus 0.3 mg/mL of diazoxide in their *** assessed included pain levels,sedation,recovery indices,PCEA usage,stress factors,and sleep *** The observation group showed lower visual analog scale scores,shorter postoperative recovery indices,fewer mean PCEA compressions,lower cortisol and blood glucose levels,and better polysomnographic parameters compared to the control group(P<0.05).The cumulative incidence of adverse reactions was lower in the observation group than in the control group(P<0.05).CONCLUSION Dezocine PCEA can effectively control the pain associated with total myomectomy,reduce the negative impact of stress factors,and have less impact on patients’sleep,consequently resulting in fewer adverse effects.

关键词： Diazoxide Patient-controlled epidural analgesia Total hysterectomy Sleep impacts Adverse effects

高效毛细管电泳法同时检测苹果中4种多酚类化合物

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分析试验室 2017年第7期36卷 750-753页

作者：杨霞冯锋刘荔贞陈泽忠山西师范大学化学与材料科学学院临汾041000 山西大同大学化学与环境工程学院大同037009

利用高效毛细管电泳法(HPCE),对苹果中根皮苷,表儿茶素,芦丁,绿原酸4种多酚类化合物进行分离与测定。在最佳实验条件:缓冲溶液为10 mmol/L Na_2B_4O_7-H_3BO_3,pH 9.2,检测波长280 nm,分离电压25 kV,测定了4种多酚类化合物的标准品,其... 详细信息

利用高效毛细管电泳法(HPCE),对苹果中根皮苷,表儿茶素,芦丁,绿原酸4种多酚类化合物进行分离与测定。在最佳实验条件:缓冲溶液为10 mmol/L Na_2B_4O_7-H_3BO_3,pH 9.2,检测波长280 nm,分离电压25 kV,测定了4种多酚类化合物的标准品,其线性范围分别为0.005~0.120,0.005~0.550,0.004~0.450,0.020~0.600 mg/mL,相关系数r在0.9977~0.9992之间,检出限分别为34.1,56.7,37.8,38.9μg/L(S/N=3)。日内及日间精密度和平均回收率范围分别为0.13%~4.5%和为96.7%~104.5%,相对标准偏差(RSD)≤3.7%(n=3)。方法可用于苹果中多种酚类物质的同时检测。

关键词：高效毛细管电泳根皮苷表儿茶素芦丁绿原酸苹果

基于创新能力培养的物理化学教学模式探索与实践

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化学教育 2016年第24期37卷 16-20页

作者：杨风霞安彩霞王爱荣河南科技学院化学化工学院

在物理化学教学中开展创新教育,对培养学生的创新意识和创新能力有着极其重要的作用.从延伸设问、布置另类作业、改进实验考核办法、丰富综合和设计实验内涵、加强综合训练和利用网络教学资源等方面,结合教学改革实践,对在物理化学教学... 详细信息

在物理化学教学中开展创新教育,对培养学生的创新意识和创新能力有着极其重要的作用.从延伸设问、布置另类作业、改进实验考核办法、丰富综合和设计实验内涵、加强综合训练和利用网络教学资源等方面,结合教学改革实践,对在物理化学教学中实施创新教育的教学模式进行了探讨.

关键词：创新教育物理化学教学模式

Impairment of Autophagic Flux After Hypobaric Hypoxia Potentiates Oxidative Stress and Cognitive Function Disturbances in Mice

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Neuroscience Bulletin 2024年第1期40卷 35-49页

作者： Shuhui Dai Yuan feng Chuanhao Lu Hongchen Zhang Wenke Ma Wenyu Xie Xiuquan Wu Peng Luo Lei Zhang Fei Fei Zhou Fei xia Li Department of Neurosurgery Xijing HospitalFourth Military Medical UniversityXi'an 710000China National Translational Science Center for Molecular Medicine and Department of Cell Biology Fourth Military Medical UniversityXi'an 710000China Department of Neurosurgery The Central Hospital of BaojiBaoji 721000China Department of Ophthalmology Xijing HospitalFourth Military Medical UniversityXi'an 710000China

Acute hypobaric hypoxic brain damage is a potentially fatal high-altitude *** plays a critical role in ischemic brain injury,but its role in hypo-baric hypoxia(HH)remains *** we used an HH chamber to demonstrate that acute HH exposure impairs autophagic activity in both the early and late stages of the mouse brain,and is partially responsible for HH-induced oxidative stress,neuronal loss,and brain *** autophagic agonist rapamycin only promotes the initiation of *** proteome analysis,a screen showed that protein dynamin2(DNM2)potentially regulates autophagic *** of DNM2 significantly increased the formation of autolysosomes,thus maintaining autophagic flux in combination with ***,the enhancement of autophagic activity attenuated oxidative stress and neurological deficits after HH *** results contribute to evidence supporting the conclusion that DNM2-mediated autophagic flux represents a new therapeutic target in HH-induced brain damage.

关键词： Autophagy-Proteomics Oxidative stress Hypobaric hypoxia-Brain injury

Targeted DNA N^(6)-methyladenine editing by dCas9 fused to METTL4 in the lepidopteran model insect Bombyx mori

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Insect Science 2024年第2期31卷 646-650页

作者： feng Chen Hao Guo Weiqun Lan Mingyi Zhou Wenjng Geng Guanwang Shen Ping Lin Qingyou xia Ping Zhao Zhiqing Li Integrative Science Center of Germplasm Creation in Western China(CHONGQING)Science City Biological Science Research CenterSouthwest UniversityChongqingChina Chongqing Key Laboratory of Sericultural Science Chongqing Engineering and Technology Research Center for Novel Silk MaterialsSouthwest UniversityChongqingChina

Dear Editor,N^(6)-Methyladenine(6mA)DNA modification is an important epigenetic mechanism with roles in regulating gene expression,nucleosome positioning,DNA damage repair,and cell cycle progression(Heyn&Esteller,2015;Luo et al.,2015;Boulias&Greer,2022).Despite progress in understanding the biological functions of 6mA,the contribution of individual 6mA installations on site-specific target genes is largely unknown,and therefore deciphering the molecular mechanism of 6mA in target gene expression has been difficult.

关键词： adenine fused Bombyx