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Climatic implications in earlywood and latewood width indices of Chinese pine in north central China

Journal of Forestry Research 2024年第3期35卷 143-153页

作者： Kaixuan yang Junzhou Zhang Haowen Fan yuan yan College of Geographic Sciences Qinghai Normal UniversityXining 810016People's Republic of China Key Laboratory of Tibetan Plateau Land Surface Processes and Ecological Conservation(Ministry of Education) Xining 810016People's Republic of China Key Laboratory of Western China's Environmental Systems(Ministry of Education) College of Earth and Environmental SciencesLanzhou UniversityLanzhou 730030People's Republic of China Gansu Liancheng Forest Ecosystem Field Observation and Research Station Lanzhou UniversityLanzhou 730333People's Republic of China School of Geography and Information Engineering University of GeoscienceWuhan 430074People's Republic of China

Latewood width(LWW)indices of trees are considered a reliable proxy of summer precipitation in the Northern ***,the strong coupling and high correlation between earlywood width(EWW)and LWW indices often prevent registration of climate signals of the LWW *** this study,328-year-long earlywood width and latewood width chronologies were developed from Chinese pine at two sites in the Hasi Mountains,north central *** climate responses of these chronologies were analyzed and the LWW index used to derive sum-mer precipitation *** analyses showed that LWW was particularly influenced by earlywood growth and recorded stronger climate signals of the previous year as EWW,rather than those of the current year with infrequent summer climate ***,after removing the effect of earlywood growth using a simple regression model,the adjusted LWW chronology(LWW_(adj))showed a strong relationship with July precipitation in dry *** suggests that the LWW_(adj) chronology has the potential to be used to investigate long-term variability in summer precipitation in drought-limited regions.

关键词： Dendroclimatology Latewood width Climate response Summer precipitation Earlywood effect

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Performance evaluation of the effect of humic acid on Anammox granular sludge:Apparent morphology,nitrogen removal and microbial community

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Journal of Environmental Sciences 2024年第10期144卷 148-158页

作者： Wenhui Huang Peiling Xu Xiang Li Yong Huang Hao Sun Wei Li Mao Zhang Miao Shi yan yuan School of Environmental Science and Engineering Suzhou University of Science and TechnologySuzhou 215009China Suzhou Hongyu Environmental Technology Company Limited by Shares Suzhou 215011China Suzhou Tianjun Environmental Technology Limited Company Suzhou 215011China Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment Suzhou University of Science and TechnologySuzhou 215009China

Humic acid(HA)is a typical refractory organicmatter,so it is of great significance to investigate its effect on the performance of Anammox granular *** the dosage ofHA≤50 mg/L,HA promotes the total nitrogen removal rate(NRR)to 1.45 kg/(m^(3)·day).When HA was between 50 and 100 mg/L,the NRR of Anammox was *** this time,the adsorption of HA causes the sludge to gradually turn fromred to brown,but the activities of heme and enzymes showed that its capacitywas not *** HA levels reached 250 mg/L,the NRR dropped to 0.11 kg/(m3·day).Moderate HA levels promoted the release of extracellular polymeric substance(EPS),but excessive HA levels lead to a decrease in EPS *** inhibited Anammox activity,which indirectly hindered the transmission of substrate and accumulated substrate *** HA promoted the increase of heterotrophicmicrobial abundance in Anammox system,the microbial diversity decreased *** the increase of HA concentration,the abundance of Candidatus_Brocadia,the main functional microorganism of Anammox system,decreased gradually,while the abundance of Candidatus_Kuenenia increased gradually.

关键词： Anammox Landfill leachate Humic acid Heme Microbial community Enzyme activity

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Graphene oxide/Al_(2)O_(3)-based diffusive memristor cells:enabling robust crossbar arrays for multidisciplinary applications

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Rare Metals 2024年第8期43卷 3997-4005页

作者： Chen Liu Jun-Cheng Jin Yi-Ke Xiao Xin-Xin Wang Ping-yuan yan yan-Qiang Cao Li-Yong Jiang Chuan-Xiang Sheng Ye-Feng Yu School of Microelectronics Nanjing University of Science and TechnologyNanjing 210094China School of Science Nanjing University of Science and TechnologyNanjing210094China School of Information Science and Technology Fudan UniversityShanghai 200433China

A memristor crossbar array (MCA) has emerged as a cutting-edge platform for advanced memory and neuromorphic computing hardware,offering unrivaled bit-level storage density.A diffusive memristor cell (DMC) is particularly well-suited for MCA integration due to its inherent threshold switching characteristics as a selector,effectively addressing current sneak path *** DMC's potential is acknowledged,it necessitates furtherexploration of their practical applicability.

关键词： crossbar arrays offering

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Factors resisting protein adsorption on hydrophilic/hydrophobic self-assembled monolayers terminated with hydrophilic hydroxyl groups

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Chinese Physics B 2024年第6期33卷 605-612页

作者：毛党新吴园燕涂育松 College of Physics Science and Technology Yangzhou UniversityYangzhou 225009China

The hydroxyl-terminated self-assembled monolayer(OH-SAM),as a surface resistant to protein adsorption,exhibits substantial potential in applications such as ship navigation and medical implants,and the appropriate strategies for designing anti-fouling surfaces are ***,we employ molecular dynamics simulations and alchemical free energy calculations to systematically analyze the factors influencing resistance to protein adsorption on the SAMs terminated with single or double OH groups at three packing densities(∑=2.0 nm^(-2),4.5 nm^(-2),and 6.5 nm^(-2)),*** the first time,we observed that the compactness and order of interfacial water enhance its physical barrier effect,subsequently enhancing the resistance of SAM to protein ***,the spatial hindrance effect of SAM leads to the embedding of protein into SAM,resulting in a lack of resistance of SAM towards ***,the number of hydroxyl groups per unit area of double OH-terminated SAM at ∑=6.5 nm^(-2) is approximately 2 to 3 times that of single OH-terminated SAM at ∑=6.5 nm^(-2) and 4.5 nm^(-2),consequently yielding a weaker resistance of double OH-terminated SAM towards ***,due to the structure of SAM itself,i.e.,the formation of a nearly perfect ice-like hydrogen bond structure,the SAM exhibits the weakest resistance towards *** study will complement and improve the mechanism of OH-SAM resistance to protein adsorption,especially the traditional barrier effect of interfacial water.

关键词： molecular dynamics simulation self-assembled monolayer resistance to protein adsorption hydrogen bond interfacial water

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Ocular surface in patients with different degrees of myopia

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International Journal of Ophthalmology(English edition) 2024年第7期17卷 1313-1321页

作者： yan-Yun Lyu Shuang Wang Xiao-Niao Chen Zhen-Yu Wang Shan-Shan Huang yan yuan Hong-Shuang Lu Wen-Li yang Li-Ya Qiao Lei Tian Ying Jie Tongren Eye Care Center Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Beijing Institute of Ophthalmology Beijing Tongren Eye CenterBeijing Tongren HospitalCapital Medical University and Beijing Ophthalmology and Visual Sciences Key LaboratoryBeijing 100730China Department of Ophthalmology the Third Medical Center of Chinese People’s Liberation Army General HospitalBeijing 100039China Department of Ophthalmology and Visual Science Tokyo Medical and Dental UniversityTokyo 113-8510Japan

AIM:To investigate the clinical features of the ocular surface in patients with different degrees of ***:A cross-sectional study was conducted involving 122 participants with myopia in Beijing Tongren Hospital from February to June,*** completing the Ocular Surface Disease Index(OSDI)score scale,measurements were taken for refraction,biometric parameters and ocular surface *** prevalence,severity and related parameters of the dry eye among different groups based on axial length(AL)were *** analysis was performed between ocular surface parameters and refraction/biometric measurement ***:Statistically significant differences were observed in refractive error,corneal thickness,anterior chamber depth,and subfoveal choroidal thickness among the groups(all P<0.05).With the increase in AL,the incidence and severity of dry eye increased significantly(P<0.05).Moreover,the tear film break-up time(BUT)shortened(P<0.05),and the corneal fluorescein staining(CFS)points increased significantly(P<0.05).OSDI scores were positively correlated with AL and spherical equivalent(SE;both P<0.05);BUT was negatively correlated with AL,SE,and corneal astigmatism(AST;all P<0.05);Schirmer I test(SIT)results were negatively correlated with AL and SE(both P<0.05).CONCLUSION:AL elongation is a risk factor for dry eye onset in myopic *** longer the AL,the more severe the dry eye is,with the increased CFS spots and tear film ***,SE and AST exhibit negative correlations with dry eye symptom scores and ocular surface parameters.

关键词： myopia axial length ocular surface dry eye

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Single-cell profiling of the pig cecum at various developmental stages

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Zoological Research 2024年第1期45卷 55-68页

作者： yan-yuan Xiao Qing Zhang Fei Huang Lin Rao Tian-Xiong Yao Si-Yu yang Lei Xie Xiao-Xiao Zou Li-Ping Cai Jia-Wen yang Bin yang Lu-Sheng Huang National Key Laboratory for Swine Genetic Improvement and Germplasm Innovation Ministry of Science and Technology of ChinaJiangxi Agricultural UniversityNanchangJiangxi 330045China

The gastrointestinal tract is essential for food digestion,nutrient absorption,waste elimination,and microbial ***-cell transcriptome profiling of the intestinal tract has greatly enriched our understanding of cellular diversity,functional heterogeneity,and their importance in intestinal tract development and *** such profiling has been extensively conducted in humans and mice,the single-cell gene expression landscape of the pig cecum remains ***,single-cell RNA sequencing was performed on 45572 cells obtained from seven cecal samples in pigs at four different developmental stages(days(D)30,42,150,and 730).Analysis revealed 12 major cell types and 38 subtypes,as well as their distinctive genes,transcription factors,and regulons,many of which were conserved in *** increase in the relative proportions of CD8^(+)T and Granzyme A(low expression)natural killer T cells(GZMA^(low)NKT)cells and a decrease in the relative proportions of epithelial stem cells,Tregs,RHEX^(+)T cells,and plasmacytoid dendritic cells(pDCs)were noted across the developmental ***,the post-weaning period exhibited an up-regulation in mitochondrial genes,COX2 and ND2,as well as genes involved in immune activation in multiple cell ***-cell crosstalk analysis indicated that IBP6^(+)fibroblasts were the main signal senders at D30,whereas IBP6^(−)fibroblasts assumed this role at the other *** cells established interactions with epithelial cells and IBP6^(+)fibroblasts in the D730 cecum through mediation of GZMA-F2RL1/F2RL2 *** study provides valuable insights into cellular heterogeneity and function in the pig cecum at different development stages.

关键词： Single-cell RNA-seq Cecum Bama Xiang pigs Various developmental stages Cellular heterogeneity

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Germ cell-specific deletion of Pex3 reveals essential roles of PEX3-dependent peroxisomes in spermiogenesis

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The Journal of Biomedical Research 2024年第1期38卷 24-36页

作者： Yejin Yao Baolu Shi Xiangzheng Zhang Xin Wang Shuangyue Li Ying Yao Yueshuai Guo Dingdong Chen Bing Wang yan yuan Jiahao Sha Xuejiang Guo State Key Laboratory of Reproductive Medicine and Offspring Health Nanjing Medical UniversityNanjingJiangsu 211166China Reproductive and Genetic Branch the First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230001China State Key Laboratory of Reproductive Medicine and Offspring Health Women's Hospital of Nanjing Medical UniversityNanjing Maternity and Child Health Care HospitalNanjing Medical UniversityNanjingJiangsu 211166China.

Peroxisomes are organelles enclosed by a single membrane and are present in various *** abruption of peroxisomes is correlated with peroxisome biogenesis disorders and single peroxisomal enzyme deficiencies that induce diverse diseases in different ***,little is known about the protein compositions and corresponding roles of heterogeneous peroxisomes in various *** transcriptomic and proteomic analyses,we observed heterogenous peroxisomal components among different organs,as well as between testicular somatic cells and different developmental stages of germ *** Pex3 is expressed in both germ cells and Sertoli cells,we generated Pex3 germ cell-and Sertoli cell-specific knockout *** Pex3 deletion in Sertoli cells did not affect spermatogenesis,the deletion in germ cells resulted in male sterility,manifested as the destruction of intercellular bridges between spermatids and the formation of multinucleated giant *** analysis of the Pex3-deleted spermatids revealed defective expressions of peroxisomal proteins and spermiogenesis-related *** findings provide new insights that PEX3-dependent peroxisomes are essential for germ cells undergoing spermiogenesis,but not for Sertoli cells.

关键词： male infertility spermiogenesis peroxisome oxidative stress PEX3

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Recurrent multisystem Langerhans cell histiocytosis involving the female genitalia: A case report

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World Journal of Clinical Cases 2024年第28期12卷 6222-6229页

作者： Chun-yan yuan Zhi-Rong Zhang Ming-Fang Guo Na Zhang Department of Gynaecology Fengdu People's HospitalChongqing 408200China Department of Gynecologic Oncology Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized TreatmentChongqing University Cancer HospitalChongqing Cancer InstituteChongqing Cancer HospitalChongqing 400030China

BACKGROUND Langerhans cell histiocytosis(LCH)is a histiocytic proliferative disease caused by clonal proliferation of Langerhans cells,which is currently defined as an inflam-matory myeloid *** is rare in adults,with an incidence of 1–2 per million,and is highly heterogeneous in clinical presentation,with unpredictable disease progression and *** SUMMARY A 52-year-old postmenopausal female patient presented to the gynecology department in July 2023 with bilateral vulvar *** was diagnosed with recurrent multisystem *** patient had previously been diagnosed with a single-system and single-focal LCH in October 2021 due to a right maxillofacial mass,which resolved after surgical treatment.A chemotherapy regimen was developed after multidisciplinary *** cycles of chemotherapy resulted in partial remission,and maintenance chemotherapy is currently being *** Recurrent LCH involving the bilateral vulva has been poorly ***-hensive imaging and pathological evaluation is important for *** model of joint multidisciplinary specialist diagnosis and treatment is worthy of clinical application.

关键词： Langerhans cell histiocytosis Chemotherapy Vulva Recurrence Case report

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数字金融、技术创新与审计质量

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科学管理研究 2024年第4期42卷 142-151页

作者：阎源鲁清仿河南大学民生学院河南开封475000 河南大学商学院河南开封475000

新质生产力要求发挥数字金融优化资源配置作用,激活企业科技创新主体意识。以沪深两市2013-2022年的沪深A股公司为样本,检验数字金融对审计质量影响,分析技术创新的中介效应。研究结果发现:数字金融提高审计质量,而企业技术创新发挥中... 详细信息

新质生产力要求发挥数字金融优化资源配置作用,激活企业科技创新主体意识。以沪深两市2013-2022年的沪深A股公司为样本,检验数字金融对审计质量影响,分析技术创新的中介效应。研究结果发现:数字金融提高审计质量,而企业技术创新发挥中介效应。进一步研究发现,数字金融的覆盖广度、使用深度以及数字化程度均能通过创新投入提高审计质量;分组检验发现,数字金融通过技术创新提高审计质量在东部地区、董事长兼任总经理中更加显著;此外,数字金融提高审计质量产生的经济后果是减少审计延迟、提高企业价值。

关键词：数字金融技术创新审计质量

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睾丸类器官在体外精子发生中的研究进展

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合成生物学 2024年第4期5卷 770-781页

作者：张博航祁晓萱袁艳南京医科大学生殖医学与子代健康全国重点实验室江苏南京211166

随着全球不孕不育问题的日益严重,特别是男性不育症的比例逐年上升,睾丸类器官的研究为这一领域提供了新的希望和策略。本综述全面探讨了睾丸类器官在模拟自然生精环境、深入探究精子发生机制以及应对男性生殖健康挑战中的应用。首先,... 详细信息

随着全球不孕不育问题的日益严重,特别是男性不育症的比例逐年上升,睾丸类器官的研究为这一领域提供了新的希望和策略。本综述全面探讨了睾丸类器官在模拟自然生精环境、深入探究精子发生机制以及应对男性生殖健康挑战中的应用。首先,介绍了睾丸的生理功能和精子发生过程的重要性,关注了睾丸组织体外培养和睾丸细胞重聚类器官的技术及其研究进展。其次,探讨了睾丸类器官在探究分子机制、药物筛选和毒性评估及男性生育力保存方面的潜在应用。最后,对当前方法的局限性和未来研究方向进行了讨论,特别是在提高体外环境下精子质量和成熟度方面的研究成果。尽管睾丸微环境复杂,在体外完整模拟人类精子发生仍面临挑战,但睾丸类器官领域的不断发展有望为临床生殖医学和男性健康研究提供新的解决方案。

关键词：睾丸类器官精子发生生殖医学睾丸微环境应用

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