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Moving Mechanism of a High-speed Insect-scale Microrobot via Electro-magnetically Induced Vibration

Journal of Bionic Engineering 2021年第3期18卷 662-673页

作者： Xinyi Liu Zhiwei Liu yangsheng Zhu Jiaming Leng Mingjing Qi Jianmei Huang xiaojun yan School of Energy and Power Engineering Beihang UniversityBeijing 100191China National Key Laboratory of Science and Technology on Aero-Engine Aero-thermodynamics Beijing 100191China Beijing Key Laboratory of Aero-Engine Structure and Strength Beijing 100191China Collaborative Innovation Center of Advanced Aero-Engine Beijing 100191China

This paper presents the moving mechanism of a high-speed insect-scale microrobot via electromagnetically induced vibration of two simply supported *** microrobot,which has a body length of 12.3 mm and a total mass of 137 mg,can achieve reciprocating lift motion of forelegs without any intermediate linkage mechanisms due to the design of an obliquely upward body tilt *** gait study shows that the body tilt angle prevents the forelegs from swinging backward when the feet contact the ground,which results in a forward friction force applied on the *** forward movement,the microrobot utilizes the elastic deformation of the simply supported beams as driving force to slide forward and its forelegs and rear legs work as pivots alternatively in a way similar to the movement of soft *** gait analysis also indicates that the moving direction of the microrobot is determined by whether its body tilt angle is obliquely upward or downward,and its moving speed is also related to the body tilt angle and as well as the body *** an applied AC voltage of 4 V,the microrobot can achieve a moving speed at 23.2 cm s1(18.9 body lengths per second),which is comparable to the fastest speed(20 cm s-1 or 20 body lengths per second)among the published insect-scale *** high-speed locomotion performance of the microrobot validates the feasibility of the presented actuation scheme and moving mechanism.

关键词： Legged microrobot electromagnetic actuation moving mechanism high-speed

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Isolation of Chloroplasts from Marine Microalga Isochrysis galbana Parke for Their Lipid Composition Analysis

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Journal of Ocean University of China 2022年第1期21卷 225-235页

作者： ZHONG Ye LI yanrong XU Jilin CAO Jiayi ZHOU Chengxu yan xiaojun Key Laboratory of Applied Marine Biotechnology Ningbo UniversityNingbo 315211China Collaborative Innovation Center for Zhejiang Marine High-Efficiency and Healthy Aquaculture Ningbo UniversityNingbo 315211China Fujian Baozhi Aquatic Science and Technology Co. Ltd.Zhangzhou 363503China Ningbo Institute of Oceanography Ningbo 315211China

Marine microalga Isochrysis galbana is an important feed species with a high nutritional *** from other uni-cellular algae,its cell contains two chloroplasts which are the major sites for lipid ***,we optimized a chloroplast isola-tion approach suitable for the isolation of *** chloroplasts and determined the purity and integrity of the isolated chloroplasts through microscopic observations and enzyme activity *** chloroplast lipids were analyzed with a ultrahigh-performance li-quid chromatography-Q Exactive Orbitrap-mass *** newly developed isolation approach is simple and reliable to isolate chloroplasts with high integrity and *** average yield of intact chloroplasts was 15.3%±0.1%.Glycolipids and acyl-glycerols were the main chloroplast *** accounted for 56.6%of chloroplast ***(DGDG),monogalactosyldiacylglycerol(MGDG)and sulfoquinovosyldiacylglycerol(SQDG)were the main *** fatty acyl R1/R2 were mostly 18:4/16:1,18:3/16:1 and 18:4/18:5 in DGDGs,14:0/18:4,18:4/18:5,18:4/18:4 and 18:3/18:4 in MGDGs and 16:0/14:0,16:0/18:3,and 18:4/18:3 in *** addition,diacylglycerol(DAG)was the most abundant acylglycerols;the content of 22:6/18:4-DAG was the *** was a little amount of glycosphingolipid(GSL)in ***(DGMG),monogalactosylmonoglyceride(MGMG),sulfoquinovosylmonoacylglycerol(SQMG),monoglyceride(MAG),phospholi-pids(PLs),ceramide(Cer)and betaine lipids were nearly undetectable in *** fatty acid proportions of DGDGs,MGDGs,SQDGs,DAGs,triglycerides(TAGs)and GSLs were either higher or lower than or similar to those of ***,our isolation approach is applicable to many aspects of chloroplast biology,and may offer a reference for the isolation of chloroplasts from other marine microalgae.

关键词： Isochrysis galbana chloroplast isolation method lipid analysis chloroplast lipid

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Physical structure and vertical distribution of chlorophyll a in winter sea ice from the northwestern Weddell Sea, Antarctica

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Acta Oceanologica Sinica 2010年第3期29卷 97-105页

作者： DAI Fangfang WANG Zipan yan xiaojun LI Zhijun ALLHUSEN Erika DIECKMANN Gerhard Ningbo University Ningbo 315211 China Zhejiang Wanli University Ningbo 315100 China Dalian University of Technology Dalian 116024 China Alfred Wegener Institute for Marine and Polar Research Bremerhaven 27570 Germany

The investigation on sea-ice biology in combination with physics, chemistry and ecology was carried out in the northwestern Weddell Sea, Antarctica, during the cruise ANT/XX III-7 on board POLARSTERN in the austral winter （August-October） in 2006. The distribution of chlorophyll a was measured and related to sea ice texture. The mean concentrations of chlorophyll a in the sea ice varied considerably with ice texture. The concentration of chlorophyll a per core ranged from 2.10– 84.40 μg/dm ^3 with a mean of 16.56 μg/dm ^3 . And the value of R （chlorophyll a / gross chlorophyll） ranged from 0.79–0.83. These high winter chlorophyll values indicate that primary production is considerable and confirms that there is significant primary production in Antarctic sea ice during winter. Thus this constitutes a major proportion of southern ocean primary production and carbon flux before the sea ice retreats.

关键词： physical structure chlorophyll a Antarctica winter sea-ice

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HY-1C Coastal Zone Imager observations of the suspended sediment content distribution details in the sea area near Hong Kong-Zhuhai-Macao Bridge in China

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Acta Oceanologica Sinica 2022年第11期41卷 126-138页

作者： Lina Cai Minrui Zhou xiaojun yan Jianqiang Liu Qiyan Ji Yuxiang Chen Juncheng Zuo Marine Science and Technology College Zhejiang Ocean UniversityZhoushan 316004China Key Laboratory of Space Ocean Remote Sensing and Application Ministry of Natural ResourcesBeijing 100081China South China Sea Fisheries Research Institute Chinese Academy of Fishery SciencesGuangzhou 510300China College of Marine Sciences Shanghai Ocean UniversityShanghai 201306China

The impacts of the Hong Kong-Zhuhai-Macao Bridge(HKZMB)on suspended sediment content(SSC)were analysed in the Zhujiang River Estuary based on data from HY-1C,which was launched in September 2018 in China,carrying Coastal Zone Imager(CZI)and Chinese Ocean Color and Temperature Scanner on it.A new SSC inversion model was established based on the relationship between in-situ SSC and the remote sensing reflectance in red and near-infrared bands of CZI ***-1C satellite data obtained from October to December 2019 were applied to retrieve SSC in the Zhujiang River *** results show that SSC around the HKZMB is ranging from 20 mg/L to 95 mg/*** change obviously on two sides of the *** flooding and ebbing period,SSC increases obviously downstream of the *** difference between upstream and downstream is ranging from 5 mg/L to 20 mg/*** flowing across the HKZMB,the change trend of SSC in most places upstream and downstream is almost the same that SSC downstream of the bridge is higher than SSC *** tidal currents interact with bridge piers,inducing vortexes downstream,leading the sediment to re-suspend downstream of the bridge *** factors,including seafloor topography and wind,can also contribute to the distribution of SSC in the Zhujiang River Estuary.

关键词： HY-1C Coastal Zone Imager(CZI) Hong Kong-Zhuhai-Macao Bridge suspended sediment content Zhujiang River Estuary

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Liver metabolomic characteristics in three different rat models of Yin deficiency based on ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry

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Journal of Traditional Chinese Medicine 2023年第2期43卷 274-285页

作者： HU Xingyao LIU Hongning yan xiaojun CHEN Zhong FU Liu LIU Ge CHEN Xuan SHANG Guangbin Jiangxi University of Chinese Medicine Research Center for Differention and Development of Traditional Chinese Medicine(TCM)Basic Theory Jiangxi Province Key Laboratory of TCM EtiopathogenisisNanchang 330004China

OBJECTIVE:To investigate the mechanism of Yin deficiency syndrome(YDS) by analyzing the liver metabolomic characteristics of three different Yin deficiency rat models METHODS:Following the TCM etiology,for clinical features and pathological manifestations of modern medicine,three kinds of animal models of Yin deficiency were induced and *** 48 Sprague-Dawley(SD) male rats were randomly divided into blank group,irritation induced model group,Fuzi-Ganjiang induced model group,and thyroxine-reserpine induced model *** successful development of model,the ultraperformance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry was carried out to detect metabolites in each *** metabolites of rat liver were analyzed for the characteristics of their *** pathway enrichment analysis and metabolic network construction were performed through various online databases including Metabolite Biology Role,Human Metabolome Database,MetaboAnalyst,and Kyoto Encyclopedia of Genes and ***:The SD rats in the experimental group showed symptoms like less weight gain,reduced diet and water intake,high body temperature,increased liver and kidney indexes,and abnormal liver and kidney tissue ***,the rats showed high increased levels of serum cyclic adenosine monophosphate,estradiol,alanine transaminase,and aspartate aminotransferase and decreased levels of cyclic guanosinc monophosphate and *** found four key interrelated metabolic pathways in the liver tissue metabolomics,including the biosynthesis of pantothenic acid and coenzyme A,and metabolism of alpha-linolenic acid metabolism,glycerophospholipid metabolism,and ***:The liver and kidney YDS is closely related to the biosynthesis of pantothenic acid and CoA and abnormal metabolism of α-linolenic acid,glycerophospholipid,and sphingolipid in SD rats.

关键词： molecular biology integrative medicine Yin deficiency syndrome syndrome complex

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Engineering two-dimensional pores in freestanding TiO_2/graphene gel film for high performance lithium ion battery

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Journal of Energy Chemistry 2018年第1期27卷 176-182页

作者： xiaojun yan Yuanyuan Wang Congcong Liu Min Guo Jingying Tao Jing Cao Dongju Fu Liyi Dai Xiaowei yang College of Chemistry and Molecular Engineering East China Normal UniversityShanghai 200241China School of Materials Science and Engineering Tongji UniversityShanghai 201804China Research Institute of Tsinghua University in Shenzhen Shenzhen 518057GuangclongChina

As the key component of electrochemical energy storage devices, an electrode with superior ions transport pores is the important premise for high electrochemical performance. In this paper, we developed a unique solution process to prepare freestanding TiO_2/graphene hydrogel electrode with tunable density and porous structures. By incorporating room temperature ionic liquids（RTILs）, even upon drying, the non-volatile RTILs that remained in the gel film would preserve the efficient ion transport channels and prevent the electrode from closely stacking, to develop dense yet porous structures. As a result, the dense TiO_2/graphene gel film as an electrode for lithium ion battery displayed a good gravimetric electrochemical performance and more importantly a high volumetric performance.

关键词： TiO2/graphene gel electrode Pore engineering Ions transport channels Lithium ion battery Volumetric performance

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Processing micrometer-sized particles in crumpled graphene network for freestanding membrane enabled by freeze casting

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Chinese Chemical Letters 2020年第1期31卷 265-268页

作者： Jing Cao Xiaoli Zhao Jiahe Wang Huanglin Dou Congcong Liu xiaojun yan Yuantao yan Min Guo Wanyu Zhao Xiaowei yang School of Materials Science and Engineering Tongji University

Graphene oxide(GO)is widely used in the construction and application of various 2 D membrane-based materials due to its unique colloidal ***,we demonstrate that micrometer-sized particles can make up freestanding membranes enabled by the extraordinary amphiphilic and polymer-like properties of graphene oxide through freeze *** 2 D macromolecule,GO could well wrap the particles for better uniformity and stability in either dispersion or ***,freeze casting plays an important role in avoiding the severe aggregation of micrometer-sized particles in the solventremoving *** reduction,the membrane exhibits good electrical conductivity while maintaining its integral structure,which can be directly used as a freestanding binder-free *** work provides a universal approach to fabricate freestanding membranes with various micrometersized materials for energy storage.

关键词： Membrane Micrometer-sized particles Graphene oxide Freeze casting Freestanding

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Analysis and Characterization of the GABA Transaminase and Succinate Semialdehyde Dehydrogenase Genes in the Microalga Isochrysis zhanjiangensis in Response to Abiotic Stresses

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中国海洋大学学报（自然科学英文版） 2024年第3期 775页

作者： TIAN Jiaojiao ZHANG Lin LU Xinyue YE Lingzhi WU Yuanyuan CHEN Deshui CAO Jiayi JIANG Jiaxin XU Jilin yan xiaojun

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参苓白术散抗溃疡性结肠炎的物质基础、作用机制及安全性评价

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武汉大学学报（理学版） 2024年第2期70卷 236-252页

作者：姜丽张文彤肖彤邓绮王静怡沈珺璐严小军黄丽萍徐国良江西中医药大学中医基础理论分化发展研究中心江西南昌330004 江西省中医病因生物学重点实验室江西南昌330004 江西省中药药理学重点实验室江西南昌330004

溃疡性结肠炎(ulcerative colitis,UC)是一种结、直肠的慢性非特异性炎症性肠病,因病症长、反复发作、缠绵难愈,被公认为难治疾病之一,且已被证实为结肠癌的癌前病变。中医认为,脾虚湿困是UC的常见病机,健脾祛湿经典方参苓白术散中的人... 详细信息

溃疡性结肠炎(ulcerative colitis,UC)是一种结、直肠的慢性非特异性炎症性肠病,因病症长、反复发作、缠绵难愈,被公认为难治疾病之一,且已被证实为结肠癌的癌前病变。中医认为,脾虚湿困是UC的常见病机,健脾祛湿经典方参苓白术散中的人参、茯苓、山药等均属药食同源中药,不良反应少、安全性较高,在治疗UC等复杂慢性疾病有显著优势。本文对近些年参苓白术散抗UC的物质基础和作用机制研究进行综述,并探讨了其在药食同源方面的应用和安全性,可望为参苓白术散在治疗UC中的临床应用和食用保健提供理论依据。

关键词：参苓白术散溃疡性结肠炎物质基础作用机制药食同源

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Identification and Expression of PPAR in Sinonovacula constricta and Their Potential Regulatory Effects on Δ6 Fad Transcription

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Journal of Ocean University of China 2021年第6期20卷 1557-1566页

作者： RAN Zhaoshou KONG Fei LIAO Kai XU Jilin LIU Xingwang SHI Peng ZHANG Mengqi WU Kaibin yan xiaojun Key Laboratory of Applied Marine Biotechnology Ningbo UniversityMinistry of Education of ChinaNingbo 315211China Collaborative Innovation Center for Zhejiang Marine High-Efficiency and Healthy Aquaculture Ningbo UniversityNingbo 315211China Fujian Baozhi Aquatic Science and Technology Co. Ltd.Zhangzhou 363503China National and Local Joint Engineering Laboratory of Marine Biotechnology and Engineering Ningbo 315211China Key Laboratory of Marine Biological Engineering Ningbo 315211China Evergreen Feed Co. Ltd.Ningbo 315211China

Peroxisome proliferator activated receptors(PPAR)are kinds of key transcriptional factors in regulating LC-PUFA *** now,little is known about PPAR in marine molluscs as well as in other *** constricta is the first marine mollusc that is proved to possess the complete LC-PUFA biosynthetic pathway,and it can be a perfect representative to clarify this *** this study,the molecular properties of *** PPAR were characterized,and corresponding potential regulatory roles in ***Δ6 fatty acyl desaturase(Fad)transcription were estimated by dual luciferase *** showed that two PPAR homologs(PPAR_a and_b)were identified in *** both contain typical features of vertebrate PPAR,suggesting highly conserved functional regions in *** phylogenetic comparison,they are clearly different with vertebrate PPAR and can be divided into two distinctive ***,they show a high expression level in gill,labial palps,mantle and *** down-regulated expressions in trochophore larva and veliger larva might be attributed to ***,the transcriptional activity of ***Δ6 Fad promoter was significantly activated by both PPAR_a and_b,indicating that *** PPAR might play a role in the regulation of LC-PUFA *** our knowledge,this is the first systematic analysis of PPAR in a marine *** results will provide a valuable reference for further researches on the function of marine molluscan PPAR and their underlying mechanisms in regulating LC-PUFA biosynthesis.

关键词： Sinonovacula constricta peroxisome proliferator activated receptors Δ6 fatty acyl desaturase long chain-polyunsaturated fatty acids

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