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Xingnao Kaiqiao acupuncture combined with Angong Niuhuang Wan for a patient under persistent vegetative state： a case report

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Frontiers of Medicine 2018年第3期12卷 334-339页

作者： Hujie Song Xiao Chen yalan yu Ling Zhang PVS Consciousness-Promoted Center of Xi'an Encephalopathy Hospital of Traditional Chinese Medicine Xi'an 710032 China

Persistent vegetative state （PVS） is a clinical condition wherein the cerebral cortex loses its function although brain stem function remains relatively intact. It has high mortality and disability rates. Although treatment for PVS is extensively studied in developed countries, little breakthrough has been made. In China, many PVS patients who were treated with traditional Chinese medicine （TCM） and acupuncture therapy were reported to have regained consciousness. In our department, we have been investigating TCM diagnosis and treatment methods for PVS for many years and have summarized a set of curative programs. Our patient is a male and 5 years and 3 months of age. He had traumatic brain injury and had been unconscious for three months on admission. Considering his condition, we adopted Xingnao Kaiqiao acupuncture, oral Angong Niuhuang Wan, and Xingnaojing intravenous drip. After the 50-day treatment, his health significantly improved and is nearly similar to that of a healthy child, indicating that the treatment is effective for PVS. Therefore, we decided to report the case and treatment methods.

关键词： PVS smbbom disease Xingnao Kaiqiao Angong Niuhuang Wan TCM acupuncture

CFD simulation on membrane distillation of NaCl solution

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Frontiers of Chemical Science and Engineering 2009年第3期3卷 293-297页

作者： Zhaoguang XU Yanqiu PAN yalan yu School of Chemical Engineering Dalian University of TechnologyDalian 116012China

A computational fluid dynamics(CFD)simu-lation that coupled an established heat and mass transfer model was carried out for the air-gap membrane distillation(AGMD)of NaCl solution to predict mass and heat behaviors of the *** effects of temperature and flowrate on fluxes were first simulated and compared with available experimental data to verify the *** profiles of temperature,temperature polarization factor,and mass flux adjacent to the tubular carbon membrane surface were then examined under different feed Reynolds number in the computational *** show that the temperature polarization phenomena can be reduced,and mass flux can be enhanced with increase in the feed Reynolds number.

关键词： membrane distillation computational fluid dynamics(CFD)simulation temperature polarization carbon membrane

From Class to Market Benign Interaction ——Explore the Marketing Operation Mode of Class Management of Higher Vocational Students

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Journal of Educational Theory and Management 2017年第1期1卷 20-23页

作者： Chaoxiong Guan yalan yu Xinjiang Agricultural Vocational Technical College Changji Xinjiang831199China

In higher vocational colleges students' daily management is the most important and most headaches, school for the higher vocational school students daily management methods, to explore education brand management, improve the students' society, the market management idea, to build with love, tolerance, confidence of higher vocational students ideological soul support, awaken their self-esteem self-improvement habit, cultivate lofty career goals;It is helpful to strengthen the students' management and employment in vocational colleges to conform to the concept of educating people, and improve the quality of education of higher vocational colleges.

关键词： Higher vocational students Marketization education Brand management Human love

Flexible,video-rate,and aberration-compensated axial dual-line scanning imaging with field-of-view jointing and stepped remote focusing

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Photonics Research 2021年第8期9卷 1477-1485页

作者： RUI JIN yalan yu DAN SHEN QINGMING LUO HUI GONG JING yuAN Britton Chance Center for Biomedical Photonics and MoE Key Laboratory for Biomedical Photonics Wuhan National Laboratory for OptoelectronicsHuazhong University of Science and TechnologyWuhan 430074China Current address:Department of Mechanical and Automation Engineering Chinese University of Hong KongShatinHong Kong HUST-Suzhou Institute for Brainsmatics JITRI Institute for BrainsmaticsSuzhou 215123China School of Biomedical Engineering Hainan UniversityHaikou 570228China

Parallel dual-plane imaging with a large axial interval enables the simultaneous observation of biological structures and activities in different views of ***,the inflexibility in adjusting the field-of-view(FOV)positions in three dimensions and optical sectioning effects,as well as the relatively small effective axial range limited by spherical aberration,have hindered the application of parallel dual-plane ***,we propose a flexible,video-rate,and defocus-aberration-compensated axial dual-line scanning imaging *** used a stepped mirror to remotely generate and detect dual axial lines with compensation for spherical aberration and FOV-jointing to rearrange into a head-to-head line for high-speed optical sectioning *** lateral and axial positions of the two FOVs could be flexibly adjusted before and during imaging,*** method also allows the adjustment of optical sectioning effects according to specific experimental *** experimentally verified the consistent imaging performance over an axial range of 300μ*** demonstrated high throughput by simultaneously imaging Brownian motions in two 250μm×250μm FOVs with axial and lateral intervals of 150μm and 240μm,respectively,at 24.5 *** also showed potential application in functional imaging by simultaneously acquiring neural activities in the optic tectum and hindbrain of a zebrafish *** proposed method is,thus,advantageous compared to existing parallel dual-plane imaging and potentially facilitates intravital biological study in large axial range.

关键词： axial field aberration

A Case Report on Treating Progressive Supranuclear Palsy with a Combination of Chinese and Western Medicine

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Journal of Clinical and Nursing Research 2024年第5期8卷 23-29页

作者： Kai Wu Yongjie Gong Shan Yang yalan yu First Clinical College Shaanxi University of Chinese MedicineXianyang 712000Shaanxi ProvinceChina Xi’an TCM Hospital of Encephalopathy Xi’an 710000Shaanxi ProvinceChina

A case of progressive supranuclear palsy in a 66-year-old woman is *** patient complained of“progressive stiffness of both lower limbs for five years,accompanied by choking and coughing for more than 1 year,”and was diagnosed with paralysis in traditional Chinese medicine(TCM),which was characterized by a deficiency of liver and kidney,and phlegm and blood stasis blocking the *** medicine diagnosed it as progressive supranuclear *** patient was diagnosed with“Parkinson’s disease”several times in the past and was given“polybasic hydrazide”and“amantadine hydrochloride tablets,”*** patient did not have significant symptomatic relief,so she sought further treatment with a combination of traditional Chinese and Western *** on the concept of deficiency and excess,this disease is categorized as a paralytic disease in Chinese medicine,and the onset of the disease is closely related to the deficiency of the body after a long period of illness,with wind,phlegm,blood stasis,and deficiency as the main pathogenetic *** treatment is based on the combination of disease and evidence,with traditional Chinese medicine and acupuncture as the main treatments,supplemented by intermediate-frequency pulsed electrical stimulation,transcranial repetitive magnetic stimulation,medicated canisters,wax therapy,traditional Chinese medicine guasha,and acupoint *** medicine is based on symptomatic treatment,and the patient’s symptoms were relieved significantly after the combination of Chinese and Western medicine.

关键词： Progressive supranuclear palsy Paralytic disease Diagnosis and treatment Deficiency and excess Combination of Chinese and Western medicine

Discussion on Traditional Chinese Medicine Treatment of Liver-Depression-Spleen-Deficiency Type Insomnia Based on the State-Target Theory and the Regulation of Microbiome-Gut-Brain Axis

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Journal of Clinical and Nursing Research 2024年第5期8卷 39-46页

作者： Kai Wu Yongjie Gong Shan Yang yalan yu First Clinical College Shaanxi University of Traditional Chinese MedicineXianyang 712000Shaanxi ProvinceChina Xi’an TCM Hospital of Encephalopathy Xi’an 710000Shaanxi ProvinceChina

Insomnia has become an urgent clinical problem in modern *** research has found that the gut flora-gut-brain axis plays an important role in regulating *** state-target theory is a product of the combination of traditional Chinese medicine and modern molecular biology *** paper clarifies the correlation between the state-target theory,the intestinal flora-gut-brain axis,and liver-depression-spleen-deficiency *** use of traditional Chinese medicine to regulate the structure and abundance of intestinal flora was also explored,aiming to integrate traditional Chinese medicine with Western medicine for the prevention and treatment of liver-depression-spleen-deficiency insomnia.

关键词： State-target theory Microbiome-gut-brain axis Liver-depression and spleen deficiency Insomnia Traditional Chinese medicine

CNKSR2 interactome analysis indicates its association with the centrosome/microtubule system

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Neural Regeneration Research 2025年第8期20卷 2420-2432页

作者： Lin Yin yalan Xu Jie Mu yu Leng Lei Ma yu Zheng Ruizhi Li Yin Wang Peifeng Li Hai Zhu Dong Wang Jing Li Institute for Translational Medicine The Affiliated Hospital of Qingdao UniversityMedical CollegeQingdao UniversityQingdaoShandong ProvinceChina School of Basic Medicine Qingdao UniversityQingdaoShandong ProvinceChina College of Life Sciences and School of PharmacyMedical CollegeQingdao UniversityQingdaoShandong ProvinceChina Department of Urology Qingdao Municipal Hospital Affiliated to Qingdao UniversityQingdaoShandong ProvinceChina

The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding *** of the CNKSR2 gene have been implicated in neurodevelopmental disorders,particularly intellectual disability,although the precise mechanism involved has not yet been fully *** has demonstrated that CNKSR2 plays a role in facilitating the localization of postsynaptic density protein complexes to the membrane,thereby influencing synaptic signaling and the morphogenesis of dendritic ***,the function of CNKSR2 in the cytoplasm remains to be *** this study,we used immunoprecipitation and high-resolution liquid chromatography-mass spectrometry to identify the interactors of *** a combination of bioinformatic analysis and cytological experiments,we found that the CNKSR2 interactors were significantly enriched in the proteome of the *** also showed that CNKSR2 interacted with the microtubule protein DYNC1H1 and with the centrosome marker *** colocalization analysis confirmed the centrosomal localization of *** we downregulated CNKSR2 expression in mouse neuroblastoma cells(Neuro 2A),we observed significant changes in the expression of numerous centrosomal *** manipulation also affected centrosome-related functions,including cell size and shape,cell proliferation,and ***,we found that CNKSR2 interactors were highly enriched in de novo variants associated with intellectual disability and autism spectrum *** findings establish a connection between CNKSR2 and the centrosome,and offer new insights into the underlying mechanisms of neurodevelopmental disorders.

关键词： autism spectrum disorder centrosome CNKSR2 intellectual disability interactome mass spectrometry microtubule neurodevelopmental disease protein complexes protein-protein interactions

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国际比较视野中的现场工程师

高等工程教育研究 2024年第5期 127-132页

作者：余雅兰匡瑛华东师范大学职业教育与成人教育研究所华东师范大学教育学部

正确认识与理解现场工程师是开展此类人才培养的基本前提,然而,目前现有认知却存在争议与误区,急需理论和实践层面深入挖掘和明确界定。通过现场工程师概念多维分析,明确其现实工作、政策制定及学术研究的定位和内涵,明确“现场工程师... 详细信息

正确认识与理解现场工程师是开展此类人才培养的基本前提,然而,目前现有认知却存在争议与误区,急需理论和实践层面深入挖掘和明确界定。通过现场工程师概念多维分析,明确其现实工作、政策制定及学术研究的定位和内涵,明确“现场工程师属于技术工程师”的基本判断。以“技术工程师”这一概念为出发点,从职能范畴、职业本质及所需能力进行比较分析,为认识现场工程师提供了清晰职业轮廓。现场工程师在工程技术教育中的地位揭示,可以为未来工程技术教育研究提出了建设性思路,推动我国工程技术人才培养模式优化与国际接轨。

关键词：现场工程师技术工程师工程技术教育

高等教育普及化阶段下我国高职教育的三重转变:挑战与应对

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江苏高教 2024年第9期 116-124页

作者：余雅兰匡瑛华东师范大学职业教育与成人教育研究所上海200062

在我国高等教育规模扩张过程中,高职教育作出了应有的贡献。随着高等教育普及化的到来,高职教育的时代角色应从量的扩张者转变为质的承担者,亟须从“外扩式”的发展转变为“内涵式”变革,以应对高职教育体系自身、外部期望与内在构成的... 详细信息

在我国高等教育规模扩张过程中,高职教育作出了应有的贡献。随着高等教育普及化的到来,高职教育的时代角色应从量的扩张者转变为质的承担者,亟须从“外扩式”的发展转变为“内涵式”变革,以应对高职教育体系自身、外部期望与内在构成的三重根本性转变,服务高质量发展的时代命题。高等教育普及化带来的从量到质的转变需要立足于我国高等教育内部分化逻辑、社会发展的需求变化逻辑与生源生态变化逻辑进行本土化分析,应基于以上三维逻辑进行人才培养定位、办学功能与办学内涵上的改革与革新。据此,高职教育亟须在人才培养定位上兼顾高层次与类型化;在教育功能上基于区域性构建专业灵活调整机制,进而实现科研功能延伸与社会服务创新;在办学内涵上基于教学灵活度与发展个性化作出改变。

关键词：高等教育普及化高职教育高质量发展高等教育多元化