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Chinese science Bulletin 1999年第4期44卷 352-356页

作者： Wang, X He, yX zhou, y Liu, s yan, Xy Tien, P Chinese Acad sci Inst Microbiol Beijing 100080 Peoples R China Beijing Ditan Hosp Dept Virol Beijing 100011 Peoples R China

The heavy chain Fd genes and K chain genes of immunoglobulin were amplified by RT-PCR from PBL of three volunteer donors with HIV-positive. Phage antibody library was constructed with the Fd genes and K chain genes using pComb3 as vector. Three-round selection against coated gpl20 showed specific enrichment of phage antibodies. After the third round selection, 40 out of 50 clones exhibited gpl20 binding capacity. The specificity of the clones was verified by ELIsA and competition inhibition ELIsA. The V_H was derived from subgroups V_Ⅱ and V_Ⅲ, V_L belonged to subgroups V_K Ⅰ and V_K Ⅲ with DNA sequencing. These results suggest that the antibodies obtained are specific to gpi20.

关键词： immunoglobulin combinatorial library phage antibody Fab gp120 HIV-1.

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美丽中国建设的制度体系研究

生态经济 2025年第1期41卷 13-18页

作者：董战峰周佳生态环境部环境规划院北京100041

制度体系是美丽中国建设的根本保障。改革开放四十多年以来,我国基本建立了一套行之有效的生态文明制度体系,但与全面推进美丽中国建设的要求相比还存在较大差距。论文分析了美丽中国建设的制度基础和面临的关键挑战,明确了促进美丽中... 详细信息

制度体系是美丽中国建设的根本保障。改革开放四十多年以来,我国基本建立了一套行之有效的生态文明制度体系,但与全面推进美丽中国建设的要求相比还存在较大差距。论文分析了美丽中国建设的制度基础和面临的关键挑战,明确了促进美丽中国建设的制度体系思路,提出了健全生态环境空间管控、责任体系、市场体系等十大重点任务,为全面推进美丽中国建设提供坚实支撑。

关键词：美丽中国生态文明制度环境治理现代化重点任务

Effects of solvent,supersaturation ratio and silica template on morphology and polymorph evolution of vanillin during swift cooling crystallization

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Particuology 2022年第6期20卷 93-104页

作者： Jinbo Ouyang Xiaohong Xing Jian Chen Limin zhou Zhirong Liu Jerry y.y.Heng Jiangxi Province Key Laboratory of Polymer Micro/Nano Manufacturing and Devices East China University of TechnologyNanchang 330013China Department of Chemical Engineering Imperial College LondonSouth Kensington CampusLondon SW72AZUK

swift cooling crystallization of vanillin was investigated in water,ethanol,isopropanol and ethyl *** and polymorph evolution of vanillin were discussed in terms of solvent,supersaturation ratio and silica ***,DsC,FTIR and microscope were used to identify polymorphs of *** showed that the nucleated polymorphs of vanillin depended largely on the solvent,supersaturation ratio and silica *** supersaturation ratios favor the nucleation of stable form I in water,and high supersaturation ratio exceeds 7 generating 100%metastable form ***,if the supersaturation ratio is too high(s>8),liquid-liquid phase separation will occur,and no crystals could be *** other solvents such as ethanol,isopropanol and ethyl acetate,only form I was ***,it should be noted that the morphology of form I prepared in ethanol,isopropanol and ethyl acetate is distinct from that obtained in water,the former is flake-like and the latter is *** nucleation of vanillin from different solution was also studied with the presence of siO_(2),siO_(2)-NH_(2)and siO_(2)−COOH templates,which did not change the nucleated polymorph of vanillin,but changed the nucleation and growth rate of stable form I.

关键词： Vanillin supersaturation ratio Nucleation Polymorph Template

RocksL:an integrated rock spectral library for better global shared services

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Big Earth Data 2023年第1期7卷 191-211页

作者： B.s.Xie s.y.zhou L.X.Wu W.F.Mao W.Wang Department of surveying Mapping and Remote Sensing ScienceSchool of Geosciences and Info-PhysicsCentral South UniversityChangshaChina Laboratory of Geo-Hazards Perception Cognition and PredicationCentral South UniversityChangshaChina

spectral data of different rocks and minerals usually show different waveforms and absorption characteristics in visible and infrared wavelengths,which allow identification of mineral species and ***,massive spectra of rock/mineral on earth surface were scattered across a variety of spectral libraries world-wide,exhibiting inconsistent data structures and measurement *** advance the data interoperability and the data usability,we collected data and information from six shared libraries with different format and measured field specimen in laboratory to establish an integrated rock spectral library(RocksL).Both the data quality of spectral curves and the integrity of descrip-tive metadata are considered in the integrated RocksL to be pub-lished in GitHub open-source *** contains not only the big spectral dataset of rocks and minerals for data service(*** sharing and retrieval)and geological discrimination,but also the characteristics dataset of key parameters/metadata(*** size,mineral composition and full-band signature,etc.)for explora-tion of data mining and knowledge *** hope that more researchers will join to improve the availability and practical value of RocksL for remote sensing *** article introduces the database structure and data processing workflow,and demon-strates a matching service and several examples of characteristic datasets of RocksL.

关键词： Rocks and minerals data interoperability integrated library geological discrimination characteristic datasets

Bonding mechanism of ultrasonic wedge bonding of copper wire on Au/Ni/Cu substrate

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中国有色金属学会会刊：英文版 2008年第1期18卷 132-137页

作者：田艳红王春青 y.Norman zhou state Key Laboratory of Advanced Welding Production Technology Harbin Institute of Technology Microjoining Laboratory Center for Advanced Materials JoiningUniversity of Waterloo

The ultrasonic wedge bonding with d25 μm copper wire was achieved on Au/Ni plated Cu substrate at ambient *** wedge bonding mechanism was investigated by using sEM/EDX,pull test,shear test and microhardness *** results show that the thinning of the Au layer occurs directly below the center of the bonding tool with the bonding power *** interdiffusion between copper wire and Au metallization during the wedge bonding is assumed negligible,and the wedge bonding is achieved by wear action induced by ultrasonic *** ultrasonic power contributes to enhance the deformation of copper wire due to ultrasonic softening effect which is then followed by the strain hardening of the copper wedge bonding.

关键词：铜导线超声波焊接金属学磨损性能

Tribological behavior of lubricant-impregnated porous polyimide

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Friction 2024年第4期12卷 711-725页

作者： Jinbang LI Ningning zhou Janet s.s.WONG school of Mechanical Engineering and Mechanics Ningbo UniversityNingbo 315211China Beijing Key Laboratory of Long-life Technology of Precise Rotation and Transmission Mechanisms Beijing Institute of Control EngineeringBeijing 100029China Department of Mechanical Engineering Imperial College LondonLondon SW72AZUK

Porous materials impregnated with lubricants can be used in conditions where limited lubricant is *** this work,three porous polyimides(PPI)with different densities were ***(PAO)impregnated PPI(iPPI)discs were rubbed against steel and sapphire *** operando observations of the iPPI-sapphire contacts show that oil is released under an applied load,forming a meniscus around *** at the outlet is created at high sliding *** amount of released oil increases with increasing PPI *** moduli,E*,estimated based on the actual contact size show that trapped oil in iPPIs contributes to load *** higher speeds,tribological rehydration of the contact occurs in low density iPPI,with that E*rises with *** high density PPIs,high speeds give a constantly high E*which is limited by the viscoelastic properties of the PPI network and possibly the rate of oil *** of iPPI-steel contacts is governed by the mechanical properties of the PPI,the flow of the lubricant,and the roughness of the PPI *** low-and medium-density(highly porous,high roughness)PPIs,large amount of oil is released,and lubrication is mainly via lubricant restricted in the contact in the pores and possibly tribological *** high density(low porosity)PPI,with lower roughness,hydrodynamic lubrication is achieved which gives the lowest *** results show that polymeric porous materials for effective lubrication require the optimization of its surface roughness,stiffness,oil flow,and oil retentions.

关键词： polyimide porous material friction mechanism polymer limited lubrication

Tomographic Data Fusion with CFD simulations Associated with a Planar sensor

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Journal of Thermal science 2017年第2期26卷 175-182页

作者： LIU J. LIU s. sUN s. zhou W. I.H.I schlaberg WANG M. yAN y. North China Electric Power University 2 Beinong RoadChangping DistrictBeijing 102206China

Tomographic techniques have great abilities to interrogate the combustion processes, especially when it is combined with the physical models of the combustion itself. In this study, a data fusion algorithm is developed to investigate the flame distribution of a swirl-induced environmental(EV) burner, a new type of burner for low NOx combustion. An electric capacitance tomography(ECT) system is used to acquire 3D flame images and computational fluid dynamics(CFD) is applied to calculate an initial distribution of the temperature profile for the EV burner. Experiments were also carried out to visualize flames at a series of locations above the burner. While the ECT images essentially agree with the CFD temperature distribution, discrepancies exist at a certain height. When data fusion is applied, the discrepancy is visibly reduced and the ECT images are improved. The methods used in this study can lead to a new route where combustion visualization can be much improved and applied to clean energy conversion and new burner development.

关键词： Process tomography data fusion EV burner flame

High thermoelectric performance of ZrTe_(2)/srTiO_(3) heterostructure

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Journal of Materiomics 2022年第3期8卷 570-576页

作者： Chun Hung suen Long Zhang Kunya yang M.Q.He y.s.Chai K.zhou Huichao Wang X.y.zhou Ji-yan Dai Department of Applied Physics The Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina College of Physics Chongqing UniversityChongqing401331China school of Physics Sun Yat-sen UniversityGuangzhou510275China

Achieving high thermoelectric pe rformance in thin fiIm heterostructures is essental for integrated and minlatured ther moelectric device *** this work,we d emonstrate a mechansm and device performance of enh anced themoelectnic perfomance induced by interfuclal effect in a tansitdon metal dichalcogenides srTiO_(3)(sTO)heterpstructure Owing to the fomed conductive interface and elevated *** ZrTe_(2)/sTO he teras tructure presents large thermoelectric power factor of 3.7×10^(5)μWcm^(-1)K^(-2) at 10 *** ion of quasi-wo dimensional conductance at the interface s atributed for the lage seebeck coffcent and high electnical conductivity leading to high thermoelectric perfor mance which is demonstrated by a prototype device attaining 3 K cooling with 100 mA current input to this heterostructure This supenior themoelectnic property makes this he teros tructure a promtsing candidate for future thermoelectric device.

关键词： Thermoelectric ZrTe_(2)thin film High mobility Interface Transition metal dichalcogenides

Polybenzimidazolium-reinforced polyimide separators to inhibit dendrites for high-security lithium-ion batteries

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science China Chemistry 2025年

作者： Guohua sun Jiaqi Cui Qingsong Zhang yisong zhou Xinluo Li yingying Zhang Zhanao Zhang Xin Zhang Jiantao Fan Pengpeng Li Lianlong Hou Nanjun Chen Hebei Key Laboratory of Flexible Functional Materials School of Materials Science and Engineering Hebei University of Science and Technology state Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical Technology Academy for Advanced Interdisciplinary studies Southern University of Science and Technology state Key Laboratory of Physical Chemistry of solid surfaces College of Chemistry and Chemical Engineering Xiamen University

Lithium dendrite formation poses a significant safety hazard in lithium-ion batteries（LIBs）, severely impeding their widespread adoption and further technological advancements. Here, we present a novel quaternized polybenzimidazolium（q-PBI） to armor polyimide（PI） nanofiber separator（q-PBI@PI）, in which the q-PBI containing lithiophilicity and anionphilicity sites serves as the multifunctional nano-layers to suppress the Li dendrite and reinforce the mechanical properties of PI nanofiber ***, the q-PBI@PI separator displays an unprecedented mechanical strength of 82.8 MPa, significantly outperforming previously reported PI nanofiber membranes（typically below 50.0 MPa）. Besides, we demonstrate that the q-PBI@PI separator simultaneously possesses low nucleation overpotential（59 mV） and exceptional average coulombic efficiency due to the suppression of Li dendrite. Importantly, q-PBI@PI-based Li||Li battery enables a stable Li plating-stripping at 1.0 m A cm-2for600 h. Attributing to these exceptional merits, the armored PI separator-based LIBs display remarkable specific capability and capacity retention. The density function theory calculations reveal that q-PBI is conducive to the desolvation of Li+and can immobilize Li+and PF6-ions near affinity sites of PI nanofibers for inhibiting the formation of Li dendrites. Our work paves a new avenue for the design of next-generation high-performing separators in LIBs.

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A dry-electrode enabled ECG-on-Chip with arrhythmia-aware data transmission

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science China(Information sciences) 2025年

作者： Xinzi XU yanxing sUO yang ZHAO Peiyi zhou Xiao HAN Qiao CAI Min WANG Jiajun yUAN Liebin ZHAO yongfu LI Guoxing WANG yong LIAN Department of Micro-Nano Electronics and MoE Key Lab of Artificial Intelligence Shanghai Jiao Tong University Pediatric AI Clinical Application and Research Center Shanghai Engineering Research Center of Intelligence Pediatrics (SERCIP) Child Health Advocacy Institute Shanghai Children's Medical Center School of MedicineShanghai Jiao Tong University shanghai Engineering Research Center of Intelligence Pediatrics (sERCIP) Xin Hua Hospital Affiliate to Shanghai Jiao Tong University School of Medicine

Early detection and treatment of cardiovascular diseases (CVDs) can be significantly enhanced through the use of flexible wearable electrocardiogram (ECG) sensors, potentially reducing CVD-related mortality. This paper introduces an ECG-on-Chip (EoC) solution tailored for flexible ECG sensors, incorporating novel features to address common challenges in wearable ECG technology. The EoC integrates a chopper-stabilized capacitively-coupled instrumentation amplifier (Cs-CCIA),ensuring a high common-mode rejection ratio (CMRR) and low noise performance. Performance is further boosted via a positive feedback loop (PFL) and a programmable gain amplifier (PGA) with shared on-chip calibration logic, which enhances input impedance and minimizes gain variability to ensure consistent algorithm performance. Additionally, a secondary chopping technique is employed to further reduce noise, achieving an input-referred noise level of 454 nVrms. The embedded algorithm within the EoC is designed to extract clinically meaningful features, facilitating robust real-time arrhythmia analysis. Fabricated using a 0.18μm CMOs process, the EoC consumes 14.9μW with a supply voltage of 1.2 V. The algorithm’s efficacy has been validated over 0.4 million heartbeats, demonstrating a sensitivity of over 99.7%for R-peak detection and 98.3%for arrhythmia analysis. To demonstrate practical application, the EoC has been integrated with a commercial Bluetooth low energy (BLE)transceiver, forming a wireless arrhythmia monitoring sensor equipped with dry electrodes. This system consumes 292.04μW in arrhythmia-aware transmission mode, supporting 13 days of operation with a 30 mAh thin-film battery.

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