检索结果-南通市图书馆

第三世界生态高峰会

作者： Ohta y. Nakagoshi N. Research associate of Kitakyushu Museum of Natural History and Human History 2-4-1 higashida yahatahigashi-ku Kitakyushyu.Fukuoka 805-0071 JAPAN Graduate School for lnternational Development and Cooperation Hiroshima Hiroshima University 1-5-1 Kagamiyama higashi-Hiroshima 739-8529 Japan

The Seto Inland Sea is the largest sea in western Japan,and the climate is mild and *** are more than 1000 islands,ranging in size from 0.001 to 595 km,of which 160 are *** work in various industries,such as agriculture,fishery,mining,and tourist *** municipalities were classified into six groups by their characteristics of industry and social *** noticed a typical island-municipality that depended on agriculture,Shimokamagari Island,and examined landscape changes during from 1947 to 2002. There is only a limited area of land suitable for agriculture and settlement,people made terraced farmlands on the *** farmlands were once used for upland crops,but were converted to orchards in 1960s along the rapid economic growth in ***, the economics of orange production have now slumped and many orchards have been *** of abandoned orchards changed into Pueraria lobata communities,and it was hard that they changed into the other *** distributed in consideration of their site conditions,such as slope direction,road density,geology,inclination, and *** the other hand,after being free from the impacts of human activities,tall pine forests changed into tall oak forests along natural *** site conditions influenced on the change of tall pine forest;geology,slope direction,inclination,and elevation. Both Orchards and tall pine forests are important elements of traditional landscape in this *** Shimokamagari Island,there are some political efforts for revaluating agricultural landscapes and appealing their own *** the Seto Inland Sea was one of the first designated national parks in *** has been evaluated that cultural landscapes of fishing villages and terraced fields have well consisted with natural landscapes including white sand beach and pine *** these traditional landscapes face to dissolution,and local municipalities have social problems of depopu

关键词： orange production island agricultural economics pine forest cultural landscape

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三叉神经中脑核神经元膜的电学特性

生理学报 1989年第6期41卷 543-554页

作者：郑谦东英穗井口敞惠西彰五郎中国医科大学生理教研室久留米大学医学部生理学教研室

用大鼠脑干脑片,给三叉神经中脑核79个神经元作了细胞内记录,测算了20个神经元膜的电学特性:静息电位-60.3±5.6mV;输入阻抗为10.5±5.4MΩ;时间常数1.3±0.5ms。电刺激可诱发动作电位,测算32个神经元的有关参数:阈电位-50—-55mV;波幅6... 详细信息

用大鼠脑干脑片,给三叉神经中脑核79个神经元作了细胞内记录,测算了20个神经元膜的电学特性:静息电位-60.3±5.6mV;输入阻抗为10.5±5.4MΩ;时间常数1.3±0.5ms。电刺激可诱发动作电位,测算32个神经元的有关参数:阈电位-50—-55mV;波幅69.5±6.1mV;超射11.9±3.6mV;波宽0.8±0.2ms。TTX(0.3μmol/L)或无钠使之消失。通以长时程矩形波电流可引起200—250Hz的2—15个重复放电,但在通电停止前终止,TEA或4-AP可延长放电。膜电位-60—-55mV时在动作电位之后可看到阈下电位波动,它不受TTX的影响,无钙时消失,TEA或4-AP使波幅增大。静息电位去极化可使45个神经元中的40个发生外向整流作用,并被TEA,4-AP或无钙抑制,超极化则发生内向整流作用,Cs或无钠抑制之。灌流液中加入各种钾通道阻断药时神经元的稳态I-V曲线发生相应变化,提示I_(DR),l_A,I_(K(Ca))及I_Q可能都与静息时的膜电导有关。

关键词：三叉神经中脑核神经元电学特性

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鼠磨牙牙本质龋粘接修复的组织学评价

中国口腔医学继续教育杂志 2007年第1期10卷 30-34页

作者： yasushi Shimada Masatugu Kawashima Takashi higashi Richard M. Foxton Junji Tagami 王冬梅（译）姬爱平（校）不详北京大学口腔医学院北京海淀区中关村南大街22号100081

目的体外评价复合树脂和玻璃离子水门汀充填体下方鼠磨牙牙本质龋的进展状况。材料和方法16只实验鼠口腔内接种变形链球菌，使其磨牙发生实验性龋齿。鼠磨牙发生的龋损在不去除腐质的情况下，直接用复合树脂或玻璃离子水门汀进行封闭。... 详细信息

目的体外评价复合树脂和玻璃离子水门汀充填体下方鼠磨牙牙本质龋的进展状况。材料和方法16只实验鼠口腔内接种变形链球菌，使其磨牙发生实验性龋齿。鼠磨牙发生的龋损在不去除腐质的情况下，直接用复合树脂或玻璃离子水门汀进行封闭。在组织病理染色切片上测量病损中细菌侵入的深度和宽度。同时检测牙髓炎性细胞的浸润程度。结果复合树脂或玻璃离子水门汀封闭龋损后，细菌入侵牙本质及龋进展的速度均明显减慢，2种封闭材料之间无显著性差异。在牙髓反应方面，龋损虽被封闭，但在牙髓中仍可观察到中到重度的炎性细胞浸润。结论通过封闭龋损可以减慢龋病的进展速度，使其由活动期转为慢性状态，但并不能完全使其静止。

关键词：牙本质龋实验鼠组织学评价粘接修复磨牙玻璃离子水门汀炎性细胞浸润复合树脂

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无舱盖船舶甲板上浪的研究

上海交通大学学报 2003年第8期37卷 1164-1167,1171页

作者：朱仁传斎藤公男上海交通大学船舶与海洋工程学院上海200030 广岛大学大学院国际协力研究科

研究船舶甲板上浪的问题是设计无舱盖船舶的重要前提 .甲板上浪和近海建筑物的越浪相似 ,均为非线性物理现象 ,因此引入越浪理论对规则波激励下的航行船舶甲板上浪量进行推算 ,利用洪水波理论与越浪理论相结合的方法对甲板上浪越过舱口... 详细信息

研究船舶甲板上浪的问题是设计无舱盖船舶的重要前提 .甲板上浪和近海建筑物的越浪相似 ,均为非线性物理现象 ,因此引入越浪理论对规则波激励下的航行船舶甲板上浪量进行推算 ,利用洪水波理论与越浪理论相结合的方法对甲板上浪越过舱口舷板的船舱进水量进行计算 .模型实验表明 ,理论计算与实验结果较为吻合 .

关键词：甲板上浪越浪洪水波模型实验

UV-Polarizing Linear Polyyne Molecules Aligned in PVA

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Chinese Journal of Chemical Physics 2019年第2期32卷 175-181,I0002页

作者： R. Sata H. Suzuki N. Ueno y. Morisawa M. Hatanaka T. Wakabayashi Department of Chemistry Kindai University Higashi-Osaka 577-8502 Japan Institute for Research Initiatives Graduate School of Science and Technology and Data Science Center Nara Institute of Science and Technology (NAIST) Ikoma 630-0192 Japan PRESTO Japan Science and Technology Agency (JST) Kawaguchi 332-0012 Japan

Electronic absorption bands of conjugated linear carbon chain molecules, namely polyynes H(C≡C)nH (n=5-7), are exploited to devise light-polarizing films applicable to the UV. Laser ablated polyynes are separated in size and dispersed in a film of polyvinyl alcohol (PVA), which is stretched to align the trapped linear polyyne molecules inside. As a nature of the structural anisotropy, transition dipole of the UV absorption for polyyne molecules is in parallel with the molecular axis and the absorption occurs only for the electromagnetic wave having the amplitude of its electric vector along the molecular axis. Aligned and fixed orientationally in the solid PVA film, polyyne molecules act as selective absorbers of one of the polarization components of incident light at particular wavelength. Using a light source of linearly polarized UV light, whose direction of polarization is rotatable, angular dependence of the absorption intensity is investigated for the stretched PVA film containing aligned polyyne molecules and analyzed in terms of an order parameter in the theory of linear dichroism.

关键词： Polyyne UV absorption Polyvinyl alcohol Linear dichroism Linearly polarized light Polarizer

新型淀粉样蛋白成像PET显像剂18F-FPyBF-2的生物分布和辐射剂量:首次在人体中的测定评估

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中华核医学与分子影像杂志 2018年第9期38卷 646-647页

作者：李雪娜 Ryuichi Nishii Tatsuya higashi Shinya Kagawa Chio Okuyama yoshihiko Kishibe Masaaki Takahashi Tomoko Okina Norio Suzuki Hiroshi Hasegawa yasuhiro Nagahama Koichi Ishizu Naoya Oishi Hiroyuki Kimura Hiroyuki Watanabe Masahiro Ono Hideo Saji Hiroshi yamauchi 中国医科大学附属第一医院核医学科 Shiga Medical Center Research Institute Dept.of Molecular Imaging and Theranostics National Institute of Radiological Sciences (NIRS)National Institutes for Quantum and Radiological Science and Technology( QST)

目的近年来,苯并呋喃衍生物5-(5-(2-(2-(2-18F-氟乙氧基)乙氧基)乙氧基)苯并呋喃-2-基)-N-甲基吡啶-2-胺(18F-FPyBF-2)被证实是淀粉样蛋白成像的显像剂。已发现18F-FPyBF-2PET/CT是评估阿尔茨海默病（AD）有用且可靠的诊断工具（higashi... 详细信息

目的近年来,苯并呋喃衍生物5-(5-(2-(2-(2-18F-氟乙氧基)乙氧基)乙氧基)苯并呋喃-2-基)-N-甲基吡啶-2-胺(18F-FPyBF-2)被证实是淀粉样蛋白成像的显像剂。已发现18F-FPyBF-2PET/CT是评估阿尔茨海默病（AD）有用且可靠的诊断工具（higashi等,Ann Nucl Med,https://***/10.1007/s12149-018-1236-1,2018）。该研究首次在健康志愿者中评估诊断剂量18F-FPyBF-2的生物分布和辐射。方法 4名健康志愿者[男3名,女1名;平均年龄（40±17）岁,年龄范围25～56岁]行18FFPyBF-2 PET/CT显像,以评估辐射暴露和药代动力学。注射后0～10 min进行身体（胸部和腹部）的动态PET/CT显像,在注射18F-FPyBF-2后进行6次15 min的全身静态显像。重建PET和CT图像数据后,通过拟合动态显像和全身显像的感兴趣体积数据来估量个体器官时间-活度曲线。用OLINDA/EXM 2.0软件判定全身有效剂量（ED）。结果动态PET显像示肝胆系统和肾是18F-FPyBF-2清除的主要途径。肝脏、胆囊、胃和肾脏呈放射性高摄取,其次是肠和膀胱。成人剂量学模型估测的ED为（8.48±1.25）μSv/MBq。男性和女性中较高吸收剂量的器官为:肝脏[（28.98±12.49）和（36.21±15. 64）μGy/MBq],大脑[（20.93±4.56）和（23.05±5.03）μGy/MBq],成骨细胞[（9.67±1.67）和（10.29±1.70）μGy/MBq],小肠[（9.12±2.61）和（11.12±3.15）μGy/MBq]和肾脏[（7.81±2.62）和（8.71±2.90）μGy/MBq]。结论成人剂量学模型的ED与用于淀粉样蛋白PET显像的其他药物所致ED相似。18F-FPyBF-2作为评估AD的诊断工具,其诊断剂量185～370 MBq对患者而言是可耐受的。

关键词：阿尔茨海默病淀粉样蛋白显像健康志愿者正电子发射断层显像术生物分布辐射剂量测定 OLINDA/EXM

Identification and characterization of NBEAL1, a novel human neurobeachin-like 1 protein gene from fetal brain, which is up regulated in glioma

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第二军医大学学报 2005年第2期26卷 232-232页

作者： Chen J Lu y Xu J Huang y Cheng H Hu G Luo C Lou M Cao G Xie y ying K Department of Neurosurgery ChangZheng Hospital Second Military Medical University Shanghai 200003China

The Beige and Chediak-higashi (BEACH) domain is highly conserved in a large family of eukaryotic proteins, and is crucial for their functions in vesicle trafficking, membrane dynamics and receptor signaling. From a fetal brain cDNA library, we isolated a cDNA of 3858 bp encoding a novel human BEACH protein, which was named as human neurobeachin-like 1 (NBEAL1) gene. The cDNA had an open reading frame (ORF) of 3006 bp encoding a putative 1001 amino acid protein. The NBEAL1 gene was located on human chromosome 2q33-2q34 and consisted of 25 exons spanning about 73 kb of the human genome. PSORT analysis indicated that the NBEAL1 protein contained a vacuolar-targeting motif ILPK, which suggested the protein might be located in the cell lysosome. The expression pattern was examined by reverse transcription/polymerase chain reaction (RT-PCR), which showed that the transcripts were highly expressed in the human brain, kidney, prostate, and testis while lowly in the ovary, small intestine, colon and peripheral blood leukocyte. In addition, the RT-PCR result of and Northern blot showed that the novel gene was highly expressed in the biopsies of different grade glioma, especially in that of lower grade ones, which suggested it might be correlative with the glioma.

关键词： reverse transcription expression pattern peripheral blood Northern blot human genome cDNA library human brain novel gene amino acid

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腰椎椎间孔狭窄引起静息性腿痛

中国骨科临床与基础研究杂志 2014年第3期6卷 190-190页

作者： yamada K Aota y.higashi T 杨庆磊尹庆水

腰椎椎间孔狭窄（foraminal stenosis，FS）诊断困难，往往使腰椎管狭窄（canal stenosis，CS）常规手术的预后不尽如人意，有学者认为，近60%的术后持续疼痛来自于腰椎FS。

关键词：腰椎管狭窄椎间孔狭窄腿痛静息术后持续疼痛常规手术 FS

Endoscopic hemostasis for hemorrhage from an ileal diverticulum

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World Journal of Gastrointestinal Endoscopy 2011年第7期3卷 154-156页

作者： Masaya Iwamuro Mariko Hanada yoko Kominami Reiji higashi Motowo Mizuno Masaya Iwamuro Kazuhide yamamoto Department of Internal Medicine Hiroshima City HospitalHiroshima 730-8518Japan Department of Gastroenterology and Hepatology Okayama University Graduate School of MedicineDentistryand Pharmaceutical SciencesOkayama 700-8558Japan

Hemorrhage from a non-Meckelian jejunoileal diverticulum is rare, and it is generally difficult to diagnose the source of the bleeding. Here, we report the case of a 59- year-old male with hemorrhage from an ileal diverticulum. Contrast computed tomography scans demonstrated the ileal diverticulum and extravasation of the contrast medium around it. The diagnosis was then made by computed tomography scans, and endoscopic mechanical hemostasis was performed under colonoscopy with three metal clips. The management of hemorrhage from jejunoileal diverticula is discussed.

关键词： Diverticulum Gastrointestinal hemorrhage Endoscopic hemostasis