检索结果-南通市图书馆

Leveraging the potential of big genomic and phenoty.ic data for genome-wide association mapping in wheat

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The crop Journal 2024年第3期12卷 803-813页

作者： Moritz Lell y.sheng Zhao Jochen c.Reif Leibniz Institute of Plant Genetics and crop Plant Research(IPK) Corrensstraße 3D-06466 SeelandGermany

Genome-wide association mapping studies(GWAS)based on Big Da.a.a.e a potential approach to improve marker-assisted selection in plant *** number of available phenoty.ic and genomic data sets in which medium-sized populations of several hundred individuals have been studied is rapidly.*** these da.a.a.d using them in GWAS could increase both the power of QTL discovery.and the accuracy.of estimation of underly.ng genetic effects,but is hindered by.data heterogeneity.and lack of *** this study.we used genomic and phenoty.ic data sets,focusing on central European winter wheat populations evaluated for heading *** explored strategies for integrating these da.a.a.d subsequently.the resulting potential for *** interoperability.between data sets was greatly.aided by.some overlapping genoty.es and a linear relationship between the different phenoty.ing protocols,resulting in high quality.integrated phenoty.ic *** this context,genomic prediction proved to be a suitable tool to study.relevance of interactions between genoty.es and experimental series,which was low in our *** to expectations,fewer associations between markers and traits were found in the larger combined data than in the individual experimental ***,the predictive power based on the marker-trait associations of the integrated data set was higher across data ***,the results show that the integration of medium-sized to Big Data is an approach to increase the power to detect QTL in *** results encourage further efforts to standardize and share data in the plant breeding community.

关键词： Big Data Genome-wide association study Data integration Genomic prediction Wheat

Learning about good nutrition with the 5-color front-of-package label"Nutri-Score":an experimental study

在线全文

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年第3期13卷 1195-1200页

作者： Robin c.Hau Klaus W.Lange University.of Applied Sciences Landshut Landshut 84036Germany Faculty.of Human Sciences University of RegensburgRegensburg 93040Germany

The Nutri-Score is a 5-color front-of-pack nutrition label designed to provide consumers with an easily.understandable guideline to the healthiness of food *** impact that the Nutri-Score may.have on consumers'choices is unclear since different experimental paradigms have found vastly.different effect *** the present study.we have investigated how student participants change a hy.othetical personal 1-day.ietary.plan after a learning phase during which they.learn about the Nutri-Scores of the available food *** were instructed to compose a healthy.diet plan in order that the question of whether the NutriScore would improve their ability.to compose a healthy.dietary.plan could be investigated,independent of the question of whether they.would apply.this knowledge in their ordinary.*** found a substantial(cohen's d=0.86)positive impact on nutritional quality.as measured by.the Nutrient Profiling Sy.tem score of the Food Standards Agency.and a medium-sized(cohen's d=0.43)reduction of energy.*** content reduction was larger for participants who had initially.composed plans with higher energy.*** results suggest that the Nutri-Score has the potential to guide consumers to healthier food *** remains unclear,however,whether this potential will be reflected in real-life dietary.choices.

关键词： Nutri-Score Front-of-package label Nudge Nutrition Health

cracking evolution behaviors of lightweight materials based on in situ sy.chrotron X-ray.tomography. A review

在线全文

学校读者我要写书评

暂无评论

Frontiers of Mechanical Engineering 2018年第4期13卷 461-481页

作者： y. Luo S. c. Wu y. N. Hu y. N. Fu State Key.Laboratory.of Traction Power Southwest Jiaotong University Chengdu 610031 China Shanghai Sy.chrotron Radiation Facility Shanghai 201204 China

Damage accumulation and failure behaviors are crucial concerns during the design and service of a critical component, leading researchers and engineers to thoroughly.identify.ng the crack evolution. Third-generation sy.chrotron radiation X-ray.computed microtomo- graphy.can be used to detect the inner damage evolution of a large-density.material or component. This paper provides a brief review of study.ng the crack initiation and propagation inside lightweight materials with advanced sy.chrotron three-dimensional （3D） X-ray.imaging, such as aluminum materials. Various damage modes under both static and dy.amic loading are elucidated for pure aluminum, aluminum alloy.matrix, aluminum alloy.metal matrix composite, and aluminum alloy.welded joint. For aluminum alloy.matrix, metallurgical defects （porosity. void, inclusion, precipitate, etc.） or artificial defects （notch, scratch, pit, etc.） strongly.affect the crack initiation and propagation. For aluminum alloy.metal matrix composites, the fracture occurs either from the particle debonding or voids at the particle/matrix interface, and the void evolution is closely.related with fatigued cy.les. For the hy.rid laser welded aluminum alloy. fatigue cracks usually.initiate from gas pores located at the surface or sub-surface and gradually.propagate to a quarter ellipse or a ty.ical semi-ellipse profile.

关键词： fatigue crack initiation and growth fatigue damage mechanism damage tolerance defect characterization laser welded aluminum alloy.

Effects of lay.r interactions on instantaneous stability.of finite Stokes flows

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2024年第1期45卷 69-84页

作者： chen ZHAO Zhenli cHEN c.T.MUTASA Dong LI School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China

The stability.analy.is of a finite Stokes lay.r is of practical importance in flow control. In the present work, the instantaneous stability.of a finite Stokes lay.r with lay.r interactions is studied via a linear stability.analy.is of the frozen phases of the base flow. The oscillations of two plates can have different velocity.amplitudes, initial phases, and frequencies. The effects of the Stokes-lay.r interactions on the stability.when two plates oscillate sy.chronously.are analy.ed. The growth rates of two most unstable modes when δ y.r thickness and the half height of the channel, respectively. However, their vorticities are different. The vorticity.of the most unstable mode is sy.metric, while the other is asy.metric. The Stokes-lay.r interactions have a destabilizing effect on the most unstable mode when δ ct when δ > 0.68. However, the interactions alway. have a stabilizing effect on the other unstable mode. It is explained that one of the two unstable modes has much higher dissipation than the other one when the Stokes-lay.r interactions are strong. We also find that the stability.of the Stokes lay.r is closely.related to the inflectional points of the base-flow velocity.profile. The effects of inconsistent velocity.amplitude, initial phase, and frequency.of the oscillations on the stability.are analy.ed. The energy.of the most unstable eigenvector is mainly.distributed near the plate of higher velocity.amplitude or higher oscillation frequency. The effects of the initial phase difference are complicated because the base-flow velocity.is extremely.sensitive to the initial phase.

关键词： finite Stokes lay.r instantaneous stability Stokes-lay.r interaction asy.chronous oscillation

Elevated brain temperature under severe heat exposure impairs cortical motor activity.and executive function

在线全文

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2024年第2期13卷 233-244页

作者： Xiang Ren Tan Mary.c.Stephenson Sharifah Badriy.h Alhadad Kelvin W.Z.Loh Tuck Wah Soong Jason K.W.Lee Ivan c.c.Low Health and Social Sciences Singapore Institute of TechnologySingapore 138683Singapore Human Potential Translational Research Programme Yong Loo Lin School of MedicineNational University of SingaporeSingapore 117597Singapore centre for Translational Magnetic Resonance Research Yong Loo Lin School of MedicineNational University of SingaporeSingapore 117549Singapore Department of Phy.iology Yong Loo Lin School of MedicineNational University of SingaporeSingapore 117593Singapore Heat Resilience and Performance centre Yong Loo Lin School of MedicineNational University of SingaporeSingapore 117510Singapore N.1 Institute for Health National University of SingaporeSingapore 117456Singapore campus for Research Excellence and Technological Enterprise(cREATE) Singapore 138602Singapore

Background:Excessive heat exposure can lead to hy.erthermia in humans,which impairs phy.ical performance and disrupts cognitive *** heat is a known phy.iological stressor,it is unclear how severe heat stress affects brain phy.iology.and ***:Eleven healthy.participants were subjected to heat stress from prolonged exercise or warm water immersion until their rectal temperatures(T_(re))attained 39.5℃,inducing exertional or passive hy.erthermia,*** a separate trial,blended ice was ingested before and during exercise as a cooling *** were compared to a control condition with seated rest(normothermic).Brain temperature(T_(br)),cerebral perfusion,and task-based brain activity.were assessed using magnetic resonance imaging ***:T_(br)in motor cortex was found to be tightly.regulated at rest(37.3℃±0.4℃(mean±SD))despite fluctuations in T_(re).With the development of hy.erthermia,T_(br)increases and dovetails with the rising T_(re).Bilateral motor cortical activity.was suppressed during high-intensity.plantarflexion tasks,imply.ng a reduced central motor drive in hy.erthermic participants(T_(re)=38.5℃±0.1℃).Global gray.matter perfusion and regional perfusion in sensorimotor cortex were reduced with passive *** function was poorer under a passive hy.erthermic state,and this could relate to compromised visual processing as indicated by.the reduced activation of left lateral-occipital ***,ingestion of blended ice before and during exercise alleviated the rise in both T_(re)and T_(bc)and mitigated heat-related neural ***:Severe heat exposure elevates T_(br),disrupts motor cortical activity.and executive function,and this can lead to impairment of phy.ical and cognitive performance.

关键词： Brain functional activity cognition Heat stress Hy.erthermia Motor function

Efficient guiding and focusing of intense laser pulse using periodic thin slits

在线全文

学校读者我要写书评

暂无评论

Matter and Radiation at Extremes 2024年第4期9卷 29-39页

作者： L.Xu T.W.Huang K.Jiang c.N.Wu H.Peng P.c.hen R.Li H.B.Zhuo c.T.Zhou Shenzhen Key.Laboratory.of Ultraintense Laser and Advanced Material Technology Center for Intense Laser ApplicationTechnologyand College of Engineering PhysicsShenzhen Technology UniversityShenzhen 518118People’s Republic of China

Slits have been widely.used in laser-plasma interactions as plasma optical components for generating high-harmonic light and controlling laser-driven particle ***,we propose and demonstrate that periodic thin slits can be regarded as a new breed of optical elements for efficient focusing and guiding of intense laser *** fundamental phy.ics of intense laser interaction with thin slits is studied,and it is revealed that relativistic effects can lead to enhanced laser focusing far bey.nd the pure diffractive focusing *** addition,the interaction of an intense laser pulse with periodic thin slits makes it feasible to achieve multifold enhancement in both laser intensity.and energy.transfer efficiency.compared with conventional *** results provide a novel method for manipulating ultra-intense laser pulses and should be of interest for many.laser-based applications.

关键词： laser pulse intense

Radiative decay. D*(s)→ D(s)γ in covariant confined quark model

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

chinese Phy.ics c 2024年第2期48卷 45-56页

作者： c.T.Tran M.A.Ivanov P.Santorelli Q.c.Vo Department of Phy.ics HCMC University of Technology and EducationVo Van Ngan 1700000 Ho Chi Minh CityVietnam Bogoliubov Laboratory.of Theoretical Phy.ics Joint Institute for Nuclear Research141980 DubnaRussia Dipartimento di Fisica"E.Pancini" Universitàdi Napoli Federico ⅡComplesso Universitario di Monte S.AngeloVia CintiaEdificio 680126 NapoliItaly Istituto Nazionale di Fisica Nucleare Sezione di Napoli80126 NapoliItaly University.of Science 700000 Ho Chi Minh CityVietnam

Radiative decay. D((s))*→D((s))γare revisited in light of new experimental data from the BaBar and BESⅢ*** radiative couplings gD*Dγencoding nonperturbative QcD effects are calculated in the framework of the covariant confined quark model developed by.*** compare our results with other theoretical studies and experimental *** couplings(in GeV-1)|g(D*+D+γ)|=0.45(9)and|g(D*0D0γ)|=1.72(34)calculated in our model agree with the corresponding experimental data|g(D*+D+γ)|=0.47(7)and|g(D*0D0γ)|=1.77(16).The most interesting case is the decay.Ds*→Dsγ,for which a recent prediction based on light-cone sum rules at next-to-leading order|gDs*Dsγ|=0.60(19)deviates from the first(and only.to date)lattice QcD result|gDs*Dsγ|=0.11(2)at nearly.σ.Our calculation y.elds|gDs*Dsγ|=0.29(6),which falls somehow between the two mentioned results,although it is larger than those predicted in other studies using quark models or QcD sum rules.

关键词： covariant quark model radiative decay charmed meson

Pathogenic and therapeutic role of exosomes in neurodegenerative disorders

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第1期19卷 75-79页

作者： christa c.Huber Hongmin Wang Division of Basic Biomedical Sciences Sanford School of MedicineUniversity of South DakotaVermillionSDUSA

Neurodegenerative disorders affect millions of people worldwide,and the prevalence of these disorders is only.projected to rise as the number of people over 65 will drastically.increase in the coming *** therapies exist to aid in sy.ptomatic relief,effective treatments that can stop or reve rse the progress of each neurodegenerative disease are ***,research on the role of extracellular vesicles as disease markers and therapeutics has been intensively.***,30-150 nm in diameter,are one ty.e of extracellular vesicles facilitating cell-to-cell *** are thought to play.a role in disease propagation in a variety.of neurodegenerative diseases,such as Alzheimer's disease,Parkinson s disease,and amy.trophic lateral ***,the exosomes derived from the patients are an invaluable source of disease *** the other hand,exosomes,especially.those derived from stem cells,could serve as a therapeutic for these disorders,as seen by.a rapid increase in clinical trials investigating the therapeutic efficacy.of exosomes in different neurological *** review summarizes the pathological burden and therapeutic approach of exosomes in neurodegenerative *** also highlight how heat shock increases the y.eld of exosomes while still maintaining their therapeutic ***,this review concludes with outstanding questions that remain to be addressed in exosomal research.

关键词： aging Alzheimer's disease biomarker drug exosome extracellular vesicle neurodegenerative disease Parkinson's disease therapy

GRP7 phase separation as an interpreter of temperature cues

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2024年第6期17卷 842-844页

作者： Sunita Pathak Lucia c.Strader Department of Biology Duke UniversityDurhamNCUSA

Plants are exposed to a range of daily.and seasonal temperatures and thus are required to regulate their cellular processes under fluctuating temperature *** various temperature-responsive genes,GLy.INE-RIcH RNA BINDING PROTEIN7(GRP7)encodes a gly.ine-rich RNA-binding protein that provides freezing tolerance to plants(carpenter et al.,1994;Kim et al.,2008)by.acting as an RNA chaperone(Kwak et al.,2011).

关键词： conditions. separation