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Effects of intelligent feedingmethod on the growth,immunity and stress of juvenile Micropterus salmoides

Artificial Intelligence in Agriculture 2021年第1期5卷 118-124页

作者： Dan Wei Fengdeng Zhang Zhangying Ye Songming Zhu Daxiong ji jian Zhao Fan Zhou Xueyan Ding College of Biosystems Engineering and Food Science Zhejiang UniversityHangzhou 310000China Ocean Academy Zhejiang UniversityZhoushan 316000China Zhejiang Fisheries Technical Extension Center Hangzhou 310023China

The feeding method is of great significance for aquaculture production and *** recent years,research on intelligent feeding,a method based on fish appetite,has been ***,however,have focused on fish welfare issues that can result from intelligent *** this study,an adaptive feeder based on a practical intelligent feeding method was designed to evaluate whether this intelligent feeding method would impair fish welfare compared to traditional automatic *** results indicated that the amount of residual feed and size inhomogeneity in the traditional group was significantly higher than that in the intelligent *** results of the growth indicator showed that theweight gain rate(WGR)in the intelligent feeding groupwas significantly higher(30.17%)than in the traditional feeding *** no significant differences were observed in the survival rate(SR),the condition factor(CF)and the hepatosomatic index(HSI),the specific growth rate(SGR)in the intelligent feeding group was significantly increased by 8.33%while the feed conversion rate(FCR)was reduced by a remarkable 17.07%compared to the traditional feeding ***,intelligent feeding significantly improved the pepsin activity of the *** terms of immunity and antioxidant capacity,however,the fish in the intelligent feeding group had a significantly lower lysozyme(LZM)level than those fed with the traditional *** superoxide dismutase(SOD),the intelligent group also displayed a lower activity value,although it was not *** intelligent feeding group had 0.14 nmol/mg protein higher malondialdehyde(MDA)activity than the traditional *** stress,although no statistical significance was observed,the cortisol level in the intelligent group was 1.9 ng/ml higher than in the traditional ***,these data suggested that the intelligent feeding method can significantly improve fish growth but may also result in stress and suppress innate immunity.

关键词： Intelligent feeding method Fish welfare Growth Immunity Stress

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Granulomatous prostatitis after bacille Calmette-Guérin instillation resembles prostate carcinoma:A case report and review of the literature

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World Journal of Clinical Cases 2023年第9期11卷 2051-2059页

作者： Yu Yao Jun-jie ji Hai-Yun Wang Li-jiang Sun Gui-Ming Zhang Department of Urology The Affiliated Hospital of Qingdao UniversityQingdao 266003Shandong ProvinceChina

BACKGROUND Bacille Calmette-Guérin(BCG)instillation is recommended in patients with nonmuscle-invasive bladder cancer who have intermediate-risk and high-risk ***,granulomatous prostatitis is a rare complication induced by BCG instillation,which can easily be misdiagnosed as prostate ***,we report a case of granulomatous prostatitis that resembled prostate *** SUMMARY A 64-year-old Chinese man with bladder cancer received BCG *** days later,he stopped BCG instillation and received anti-infective therapy due to the urinary tract *** months after BCG restart,he had rising total prostate-specific antigen(PSA)(9.14 ng/mL)and decreasing free PSA/total PSA(0.09).T2-weighted images of magnetic resonance imaging(MRI)showed a 28 mm×20 mm diffuse low signal abnormality in the right peripheral zone,which was markedly hyperintense on high b-value diffusion-weighted MRI and hypointense on apparent diffusion coefficient map *** Prostate Imaging Reporting and Data System score of 5 and possibility of prostate cancer,a prostate biopsy was *** showed typical features of granulomatous *** nucleic acid test for tuberculosis was *** was finally diagnosed with BCG-induced granulomatous ***,he stopped BCG instillation and received anti-tuberculosis *** 10 mo follow-up,he had no evidence of tumor recurrence or symptoms of *** Temporarily elevated PSA and high followed by low signal abnormality on diffusion-weighted MRI are important indicators of BCG-induced granulomatous prostatitis.

关键词： Granulomatous prostatitis Prostate cancer Bacille Calmette-Guérin Magnetic resonance imaging Prostate-specific antigen Case report

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MicroRNA-630 alleviates inflammatory reactions in rats with diabetic kidney disease by targeting toll-like receptor 4

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World Journal of Diabetes 2024年第3期15卷 488-501页

作者： Qi-Shun Wu Dan-Na Zheng Cheng ji Hui Qian Juan jin Qiang He Graduate School Medical College of Soochow UniversitySuzhou 215006Jiangsu ProvinceChina Department of Nephrology Zhejiang Provincial People’s HospitalAffiliated People’s HospitalHangzhou 314408Zhejiang ProvinceChina Department of Nephrology Affiliated Hospital of Jiangsu UniversityZhenjiang 212001Jiangsu ProvinceChina Department of Nephrology Zhejiang Provincial People’s HospitalAffiliated People’s HospitalHangzhou Medical CollegeHangzhou 314408Zhejiang ProvinceChina Molecular Inspection Laboratory School of MedicineJiangsu UniversityZhenjiang 212000Jiangsu ProvinceChina Department of Nephrology The First Affiliated Hospital of Zhejiang Chinese Medical UniversityZhejiang Provincial Hospital of Traditional Chinese MedicineHangzhou 310060Zhejiang ProvinceChina

BACKGROUND Diabetic kidney disease(DKD)is a major complication of diabetes *** tubular epithelial cell(TEC)damage,which is strongly associated with the inflammatory response and mesenchymal trans-differentiation,plays a significant role in DKD;However,the precise molecular mechanism is *** recently identified microRNA-630(miR-630)has been hypothesized to be closely associated with cell migration,apoptosis,and ***,the association between miR-630 and DKD and the underlying mechanism remain *** To investigate how miR-630 affects TEC injury and the inflammatory response in DKD *** Streptozotocin was administered to six-week-old male rats to create a hypergly cemic diabetic *** the second week of modeling,the rats were divided into control,DKD,negative control of lentivirus,and miR-630 overexpression *** 8 wk,urine and blood samples were collected for the kidney injury assays,and renal tissues were removed for further molecular *** target gene for miR-630 was predicted using bioinformatics,and the association between miR-630 and toll-like receptor 4(TLR4)was confirmed using in vitro investigations and double luciferase reporter gene *** of miR-630 in DKD rats led to changes in body weight,renal weight index,basic blood parameters and histopathological *** The expression level of miR-630 was reduced in the kidney tissue of rats with DKD(Png quantitative reverse transcription polymerase chain *** mRNA expression level of miR-630 was significantly lower in the high-glucose(HG)and HG+mimic negative control(NC)groups than in the normal glucose(ng)group(P<0.05).In contrast,the mRNA expression level of TLR4 was significantly higher in these groups(P<0.05).However,miR-630 mRNA expression increased and TLR4 mRNA expression significantly decreased in the HG+miR-630 mimic group than in the HG

关键词： Diabetic kidney disease MicroRNA-630 Toll-like receptor 4 Mouse model Renal tubular epithelial cells damage Hyperglycemic model

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头孢曲松钠联合痰热清注射液治疗小儿支气管肺炎的效果

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中国当代医药 2017年第18期24卷 87-89页

作者：杨继红深圳市第二人民医院儿科广东深圳518035

目的观察头孢曲松钠联合痰热清注射液治疗小儿支气管肺炎的临床效果。方法选取我院2014年3月~2015年12月住院部收治的支气管肺炎患儿120例,将其随机分为两组,每组60例。观察组采用头孢曲松钠联合痰热清注射液治疗,对照组采用头孢曲松钠... 详细信息

目的观察头孢曲松钠联合痰热清注射液治疗小儿支气管肺炎的临床效果。方法选取我院2014年3月~2015年12月住院部收治的支气管肺炎患儿120例,将其随机分为两组,每组60例。观察组采用头孢曲松钠联合痰热清注射液治疗,对照组采用头孢曲松钠联合氨溴索注射液治疗。比较两组患者的总有效率、体温恢复时间、临床症状消失时间、肺部体征消失时间、住院时间。结果观察组患者的总有效率95.00%,明显高于对照组的76.67%(P<0.05);观察组患者的体温恢复时间为(1.61±0.36)d,临床症状消失时间为(3.51±0.55)d,肺部体征消失时间为(5.32±1.25)d,住院时间为(7.25±2.11)d,短于对照组的(2.61±0.45)、(4.51±1.05)、(6.45±1.42)、(8.56±2.30)d(P<0.05)。结论头孢曲松钠联合痰热清注射液治疗小儿支气管肺炎的效果显著,可有效改善患者的临床表现,缩短病程,临床上值得推广。

关键词：头孢曲松钠痰热清注射液小儿支气管肺炎

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最美的镜头对准江郎山

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品位 2022年第6期 14-16页

作者：张建成北京微电影产业协会

2017年,第二届浙江省微电影奖颁奖典礼首次落户江山,至今已在江山市连续举办4届。江山有什么魅力吸引着“微电影人”?在第七届浙江省微电影表彰典礼举办前夕,且听导演张建成、电影人毛小燕、演员郑华敢和影评人向宇,说一说江山和微电影... 详细信息

2017年,第二届浙江省微电影奖颁奖典礼首次落户江山,至今已在江山市连续举办4届。江山有什么魅力吸引着“微电影人”?在第七届浙江省微电影表彰典礼举办前夕,且听导演张建成、电影人毛小燕、演员郑华敢和影评人向宇,说一说江山和微电影的情缘.

关键词：微电影影评人魅力吸引江山市江郎山

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丁苯酞对急性缺血性卒中患者认知功能的影响

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中外医疗 2016年第4期35卷 108-109页

作者：孙继锋开封市陇海医院神经内科河南开封475003

目的探讨急性缺血性卒中患者应用丁苯酞治疗对认知功能的影响,以丰富临床治疗经验。方法整群选取2014年3月—2015年3月在该院收治的急性缺血性卒中患者72例,根据入院治疗顺序随机分成对照组与观察组各36例,对照组给予标准化治疗,观察组... 详细信息

目的探讨急性缺血性卒中患者应用丁苯酞治疗对认知功能的影响,以丰富临床治疗经验。方法整群选取2014年3月—2015年3月在该院收治的急性缺血性卒中患者72例,根据入院治疗顺序随机分成对照组与观察组各36例,对照组给予标准化治疗,观察组则使用丁苯酞予以治疗。经治疗后,统计两组的认知功能情况,并进行对比。结果治疗后观察组的认知功能损害率为50%(18/36),显著低于对照组77.78%(28/36),差异有统计学意义(P<0.05)。结论急性缺血性卒中患者应用丁苯酞治疗显著改善了患者的认知功能,值得推广。

关键词：急性缺血性卒中丁苯酞认知功能

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Characteristics and source attribution of PM2.5 during 2016 G20 Summit in Hangzhou: Efficacy of radical measures to reduce source emissions

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Journal of Environmental Sciences 2021年第8期33卷 47-65页

作者： Ke Chen Sarah E.Metcalfe Huan Yu jingsha Xu Honghui Xu Dongsheng ji Chengjun Wang Hang Xiao Jun He Department of Chemical and Environmental Engineering University of Nottingham Ningbo ChinaNingbo315100China School of Geography University of NottinghamNottinghamNG72RDUK Department of Atmospheric Science School of Environmental StudiesChina University of GeosciencesWuhan430074China School of Geography Earth and Environmental SciencesUniversity of BirminghamEdgbastonBirminghamB152TTUnited Kingdom Zhejiang Institute of Metrological Sciences Hangzhou310008China State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing100029China College of Resources and Environmental Science South-Central University for NationalitiesWuhan430074China Centre for Excellence in Regional Atmos.Environ.Institute of Urban Environment Chinese Academy SciencesXiamen361021China Key Laboratory of Carbonaceous Wastes Processing and Process Intensification Research of Zhejiang Province University of Nottingham Ningbo ChinaNingbo315100China

A field campaign was conducted to study the PM2.5 and atmospheric gases and aerosol’s components to evaluate the efficacy of radical measures implemented by the Chinese government to improve air quality during the 2016 G20 Summit in Hangzhou *** lower level of PM2.5(32.48±11.03μg/m3)observed during the control period compared to precontrol and post-control periods showed that PM2.5 was alleviated by control *** on the mass concentrations of particulate components,the emissions of PM2.5 from local sources including fossil fuel,coal combustion,industry and construction were effectively reduced,but non-exhaust emission was not reduced as effectively as *** accumulation of SNA(SO42-,NO3-,NH4+)was observed during the control period,due to the favourable synoptic weather conditions for photochemical reactions and heterogeneous *** of transboundary transport during the control period,air masses from remote areas contributed significantly to local ***,secondary organic carbon(OCsec)exhibited more sensitivity than primary organic carbon(OCpri)to control measures,and the increased nitrogen oxidation ratio(NOR)implied the regional transport of aged sec-ondary aerosols to the study ***,the results from various approaches revealed that local pollution sources were kept under control,indicating that the implementation of mitigation measures were helpful in improving the air quality of Hangzhou during G20 *** reduce ambient levels of PM2.5 further in Hangzhou,regional control policies may have to be taken so as to reduce the impact of long-range transport of air masses from inland China.

关键词： G20 Summit PM2.5 Long-range transport CMB model

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Prostate volume as an independent predictor of prostate ：ancer in men with PSA of 10-50 ng ml-1

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Asian Journal of Andrology 2013年第3期15卷 409-412页

作者： Ping Tang Xiao-Long jin Matthew Uhlman Yu-Rong Lin Xiang-Rong Deng Bin Wang Ke-ji Xie Department of Urology Guangzhou First People's Hospital Guangzhou Medical University Guangzheu 510180 China postgraduate Institute Southern Medical University Guangzhou 510515 China Department of Urology University of Iowa Iowa City IA 52242 USA

Prostate volume （PV） has been shown to be associated with prostate cancer （PCa） detection rates in men with a prostate-specific antigen （PSA） in the ＇grey zone＇（2.0-10.0 ng ml-1）. However, the PSA ＇grey zone＇ in Asian men should be higher because the incidence of PCa in Asian men is relatively low. Therefore, we evaluated the association between PV and PCa detection rates in men with PSAs measuring 10-50 ng ml-1, Men who underwent a 13-core prostatic biopsy with PV documentation participated in the study. A multivariate stepwise regression was used to evaluate whether the PV at time of prostate biopsy could predict the risk of PCa. The rates of PCa among men in different PSA ranges, stratified by PV medians （〈60 and ≥60 ml）, were calculated. There were 261 men included in the final analysis. PV was the strongest predictor of PCa risk （odds ratio, 0.02; P〈0.001） compared to other variables. The PCa rates in men with PVs measuring 〈60 and ≥ 60 ml in the 10-19.9 ng ml-1 PSA group were 40.6% and 15.1%, respectively, while the rates for men with PSAs measuring 20-50 ng ml- 1 were 65.1% and 26.8%. PV is an independent predictor of PCa in men with PSA measuring 10-50 ng ml-1. In clinical practice, particularly for those countries with lower incidences of PCa, PV should be considered when counselling patients with PSAs measuring 10-50 ng ml-1 regarding their PCa risks.

关键词： prostate biopsy prostate cancer (PCa) prostate-specific antigen (PSA) prostate volume (PV)

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断桥铝合金双层窗施工技术分析

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价值工程 2016年第17期35卷 87-89页

作者：王贵吉中山盛兴股份有限公司中山528412

随着建筑行业的快速发展,对门窗施工技术也提出更高的要求。从以往建筑中窗户的应用情况看,其很难实现室内温度与空气的控制,无法满足当前居住者对居住环境的舒适度要求。在此背景下,便提出铝合金双层窗施工,其对于改变以往门窗设计的弊... 详细信息

随着建筑行业的快速发展,对门窗施工技术也提出更高的要求。从以往建筑中窗户的应用情况看,其很难实现室内温度与空气的控制,无法满足当前居住者对居住环境的舒适度要求。在此背景下,便提出铝合金双层窗施工,其对于改变以往门窗设计的弊病,可起到明显改善作用。但如何做好双层窗施工工作,又成为现行施工中面临的主要问题。本文将对断桥铝合金双层窗施工主要特征、施工中的主要工序以及具体的施工案例进行探析。

关键词：断桥铝合金施工技术双层窗

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Molecular dynamics simulations of surfactant adsorption at oil/water interface under shear flow

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Particuology 2019年第3期17卷 36-43页

作者： Ying Ren Qiang Zhang Ning Yang ji Xu jialin Liu Ruixin Yang Christian Kunkelmann Eduard Schreiner Christian Holtze Kerstin Miilheims Bernd Sachweh State Key Laboratory of Multiphase Complex Systems Institute of Process Engineering Chinese Academy of Sciences P.O. Box 353 Beijing 100190 China Center for Mesoscience (COM) Institute of Process Engineering Chinese Academy of Sciences P.O. Box 353 Beijing 100190 China China University of Petroleum-Beijing Beijing 102249 China University of Shanghai for Science and Technology Shanghai 200093 China BASFSE 67056 Ludwigshafen am Rhein Germany BASF Advanced Chemicals Co. Ltd. Shanghai 200137 China

Surfactants are extensively used in many chemical products to improve their stability, appearance, texture, and rheology. Precise control of the emulsion droplet size distribution, which depends on the characteristics of the surfactant used, is important for target-oriented product design. A complete understand! ng of the structures and dynamics of emulsion droplets at the reactor level requires coupling of two mesoscale physical constraints, that at the interfacial level, i.e., smaller than a single droplet (Mesoscale- 1), and that at the device level, i.e., larger than a single droplet (Mesoscale-2). In this work, the structures and adsorption kinetics of Mesoscale-1 surfactant molecules were studied via coarse-grained molecular dynamics. A non-equilibrium model that could introduce stable shear flow into the simulation box was used to investigate the interfacial structures at the droplet interface under different shear rates. The configurations of the surfactant molecules and adsorption amounts were compared with those obtained without flow. The adsorption kinetics for different shear rates were compared to determine the effects of hydrodynamic interactions. The dominant mechanisms governing the dynamic structures can thus be summarized as maximization of the adsorption density at the interface and minimization of flow resistance in the bulk phase (water and/or oil molecules). A scheme for coupling between Mesoscale-1 and Mesoscale-2 is proposed. This method is promising for the incorporation of interfacial structure effects into the hydrodynamics at the reactor device level for the manipulation of chemical products.

关键词： Surfactant adsorption Molecular dynamics simulation Mesoscale modeling Shear flow

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