Granulomatous prostatitis after bacille Calmette-Guérin instillation resembles prostate carcinoma:A case report and review of the literature
作者机构：Department of UrologyThe Affiliated Hospital of Qingdao UniversityQingdao 266003Shandong ProvinceChina
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2023年第11卷第9期
页 面：2051-2059页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：Supported by the Natural Science Foundation of Shandong Province No.ZR2021MH354
主 题：Granulomatous prostatitis Prostate cancer Bacille Calmette-Guérin Magnetic resonance imaging Prostate-specific antigen Case report
摘 要：BACKGROUND Bacille Calmette-Guérin(BCG)instillation is recommended in patients with nonmuscle-invasive bladder cancer who have intermediate-risk and high-risk ***,granulomatous prostatitis is a rare complication induced by BCG instillation,which can easily be misdiagnosed as prostate ***,we report a case of granulomatous prostatitis that resembled prostate *** SUMMARY A 64-year-old Chinese man with bladder cancer received BCG *** days later,he stopped BCG instillation and received anti-infective therapy due to the urinary tract *** months after BCG restart,he had rising total prostate-specific antigen(PSA)(9.14 ng/mL)and decreasing free PSA/total PSA(0.09).T2-weighted images of magnetic resonance imaging(MRI)showed a 28 mm×20 mm diffuse low signal abnormality in the right peripheral zone,which was markedly hyperintense on high b-value diffusion-weighted MRI and hypointense on apparent diffusion coefficient map *** Prostate Imaging Reporting and Data System score of 5 and possibility of prostate cancer,a prostate biopsy was *** showed typical features of granulomatous *** nucleic acid test for tuberculosis was *** was finally diagnosed with BCG-induced granulomatous ***,he stopped BCG instillation and received anti-tuberculosis *** 10 mo follow-up,he had no evidence of tumor recurrence or symptoms of *** Temporarily elevated PSA and high followed by low signal abnormality on diffusion-weighted MRI are important indicators of BCG-induced granulomatous prostatitis.
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