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BIOCELL 2017年第1期41卷 19-26页

作者： Mian LIU xumeng zhang Center for Reproductive Medicine Department of Obstetrics and GynecologyNanfang HospitalSouthern Medical UniversityGuangzhou 510515P.R.C State Key Laboratory of Biocontrol School of Life SciencesSun Yat-sen UniversityGuangzhou 510006P.R.C

Bladder,kidney,prostate and testicular carcinoma are the top four genitourinary cancers in *** we analyzed mRNA and miRNA expression profiles of carcinomas of the bladder(TCC),kidney(ccRCC)and testis(TGCT)to uncover their specific regulatory *** gene expression profiles of GSE31617 were downloaded from GEO database,which contained 27 samples,including 10 TCC,7 TGCT and 10 *** up-and downregulated differentially expressed genes(DEGs)and differentially expressed microRNAs(DEmiRNAs)of each cancer were selected and target genes of DEmiRNAs were *** interaction network of the shared genes and target genes of DEmiRNAs of each cancer was predicted by STRING and constructed by *** each cancer,we build regulatory networks of hub genes selected and conducted GO analysis of enriched ***,we chose four hub genes(SALL4,RHEB,CDC42 and TNN)for survival analysis in OncoLnc database,and they all had effects on the survival rate of another genitourinary cancer-kidney renal clear cell carcinoma(KIRC).In conclusion,the present study indicated that the identified hub genes promote our understanding of molecular mechanisms underlying the development of three genitourinary cancers,and might be used as molecular targets and diagnostic biomarkers for the treatment of them.

关键词： Genitourinary cancers Differentially expressed genes Differentially expressed miRNAs Hub genes

Modulating 3D memristor synapse by analog spiking pulses for bioinspired neuromorphic computing

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Science China(Physics,Mechanics & Astronomy) 2018年第8期61卷 75-81页

作者： Qi Liu xumeng zhang Qing LUO XiaoLong Zhao HangBing Lv ShiBing Long Ming Liu Key Laboratory of Microelectronics Device&Integrated Technology Institute of MicroelectronicsChinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China

Memristor based artificial synapses have demonstrated great potential for bioinspired neuromorphic computing in recent years. To emulate synaptic fimctions, such as short-term plasticity and long-term potentiation/depression, square pulses or combined complex pulse groups are applied on the device. However, in biological neuron systems, the action potentials are analog pulses with similar amplitudes. Furthermore, in biological systems, the intensity of the stimulus is coded into the frequency of action potentials to modulate the weight of synapses. Toward this programming method, we applied a series of analog spiking pulses with same peaks on Ru/TiOJTiN 3D memristor to emulate synaptic functions, such as long-term potentiation/depression and synaptic saturation. Moreover, we demonstrated the conductance change of the device under different stimulus frequencies of analog spiking pulses and described the statistical results of conductance change value, which shows that the device conductance has a larger change value under a higher spiking frequency with identical pulse number. These results show that the analog spiking pulses can well modulate the memristor-based synaptic weight and have a great potential for bioinspired computing in the future.

关键词： 3D memristor analog spiking pulses artificial synapse spiking frequency

Impact of Ta/Ti electrodes on linearities of TaOx-based resistive random-access memories for neuromorphic computing

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Science China(Physics,Mechanics & Astronomy) 2020年第9期63卷 83-88页

作者： YiLin Fang Tuo Shi xumeng zhang ZuHeng Wu JunJie An JinSong Wei Jian Lu Qi Liu School of Information Science and Technology University of Science and Technology of ChinaHefei 230027China Key Laboratory of Microelectronics Device&Integrated Technology Institute of MicroelectronicsChinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China Zhejiang Laboratory Hangzhou 311122China

In this work,by incorporating different electrodes(Ta/Ti)onto TaOxdielectric layer,we studied both the conductance reading and conductance updating(long term potentiation and depression)linearities in the two RRAM *** to the composition modulation(CM)mechanism,the Ta-electrode device shows better conductance reading and updating *** RRAM device linearities directly influence the performance of the neural network when the devices are used as *** evaluation of a two-layer neural network considering the conductance reading and updating linearity factors further confirm that both the training and inference accuracies of Ta electrode device are better than those of the Ti electrode *** believe that this work could serve as a powerful reference for engineering synaptic devices with good linearity for neuromorphic computing applications.

关键词： RRAM conductance reading linearity conductance updating linearity neuromorphic computing

A neuromorphic core based on threshold switching memristor with asynchronous address event representation circuits

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Science China(Information Sciences) 2022年第2期65卷 211-217页

作者： Jinsong WEI Jilin zhang xumeng zhang Zuheng WU Rui WANG Jian LU Tuo SHI Mansun CHAN Qi LIU Hong CHEN School of Microelectronics University of Science and Technology of China Institute of Microelectronics of Chinese Academy of Sciences Zhejiang Lab Department of Microelectronics and Nanoelectronics Tsinghua University Department of Electronic & Computer Engineering The Hong Kong University of Science and Technology

The full memristive network hardware features high density and excellent scalability. However,recent researches on the full memristive network have been limited to a single-layer network, due to the lack of effective and flexible communication between neurons. In this design, we demonstrate a neuromorphic core based on Ag/Si O2/Au threshold switching memristor, which has built-in asynchronous address event representation(AER) circuits to provide flexible communication between neurons. Since temporally sparse spikes are the medium of communication between neurons, the AER circuits are designed to transmit spikes serially which have been encoded with neurons’ addresses before transmission. With the asynchronous circuits design, the AER circuits will detect neurons’ output in real-time. To test the performance of the neuromorphic core, we designed a behavioral simulator for the neuromporphic core to simulate the liquid state machine(LSM) network, which achieves a 100% recognition rate in the free spoken digital dataset. The simulation results show that the neuromorphic core obtains 35 times higher performance than the CPU and111 times higher energy efficiency than the GPU.

关键词： leaky-integration-and-fire (LIF) memristor threshold switching artificial neuron AER circuits asynchronous circuits on-chip communication

Reliable ferroelectricity down to cryogenic temperature in wakeup free Hf_(0.5)Zr_(0.5)O_(2)thin films by thermal atomic layer deposition

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Journal of Semiconductors 2024年第3期45卷 33-37页

作者： Shuyu Wu Rongrong Cao Hao Jiang Yu Li xumeng zhang Yang Yang Yan Wang Yingfen Wei Qi Liu State Key Laboratory of Fabrication Technologies for Integrated Circuits Institute of MicroelectronicsChinese Academy of SciencesBeijing 100029China Frontier institute of Chip and System Fudan UniversityShanghai 200433China College of Electronic Science and Technology National University of Defense TechnologyChangsha 410073China University of Chinese Academy of Sciences Beijing 100049China

The performance and reliability of ferroelectric thin films at temperatures around a few Kelvin are critical for their application in *** this work,TiN/Hf_(0.5)Zr_(0.5)O_(2)/TiN capacitors that are free from the wake-up effect are investigated systematically from room temperature(300 K)to cryogenic temperature(30 K).We observe a consistent decrease in permittivity(εr)and a progressive increase in coercive electric field(Ec)as temperatures *** investigation reveals exceptional stability in the double remnant polarization(2P_(r))of our ferroelectric thin films across a wide temperature ***,at 30 K,a 2P_(r)of 36μC/cm^(2)under an applied electric field of 3.0 MV/cm is ***,we observed a reduced fatigue effect at 30 K in comparison to 300 *** stable ferroelectric properties and endurance characteristics demonstrate the feasibility of utilizing HfO_(2)based ferroelectric thin films for cryo-electronics applications.

关键词： hafnia-zirconia solid solution ferroelectricity cryogenic temperature wake-up effect

Numerical Investigation on Residual Stress and Warping of Planar SOFC in Manufacturing

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Journal of Power and Energy Engineering 2022年第5期10卷 54-64页

作者： xumeng zhang Jianguo Zhu Wenlong Li Faculty of Civil Engineering and Mechanics Jiangsu University Zhenjiang China

Residual thermal stresses and warping of the anode-supported planar solid oxide fuel cell (SOFC) were estimated numerically. A 3D finite element (FE) model with viscoelastic constitutive equations was established to calculate the residual stress and warping for the cell. In the fabrication of the cells, some mechanical restriction was employed during the high-temperature treatment followed by a cooling stage in order to prevent the button cell from warping, and then from these specific boundaries and loading conditions, a FE simulation was used to calculate the distribution of the internal stresses in the cell. The results indicate that the concentration of compressive stress appears in the electrolyte layer, and that could cause interfacial micro-cracks or even cohesive failure. Furthermore, from the numerical study, the annealing time (or continuous cooling) is related to the residual stress in the material due to creeping. The compressive stress in the electrolyte layer can be reduced significantly by increasing the cooling time. Therefore, it is possible to optimize the annealing time in order to make the SOFCs flat and have less residual stress, improving the mechanical durability.

关键词： Solid Oxide Fuel Cell Residual Stress Warping Numerical Simulation

Uniform, fast, and reliable CMOS compatible resistive switching memory

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Journal of Semiconductors 2022年第5期43卷 109-115页

作者： Yunxia Hao Ying zhang Zuheng Wu xumeng zhang Tuo Shi Yongzhou Wang Jiaxue Zhu Rui Wang Yan Wang Qi Liu Key Laboratory of Microelectronic Devices&Integrated Technology Institute of MicroelectronicsChinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China School of Integrated Circuits Anhui UniversityHefei 230601China Frontier Institute of Chip and System Fudan UniversityShanghai 200433China

Resistive switching random access memory(RRAM) is considered as one of the potential candidates for next-generation memory. However, obtaining an RRAM device with comprehensively excellent performance, such as high retention and endurance, low variations, as well as CMOS compatibility, etc., is still an open question. In this work, we introduce an insert TaO_(x) layer into HfO_(x)-based RRAM to optimize the device performance. Attributing to robust filament formed in the TaO_(x) layer by a forming operation, the local-field and thermal enhanced effect and interface modulation has been implemented simultaneously. Consequently, the RRAM device features large windows(> 10^(3)), fast switching speed(-10 ns), steady retention(> 72h), high endurance(> 10^(8) cycles), and excellent uniformity of both cycle-to-cycle and device-to-device. These results indicate that inserting the TaO_(x) layer can significantly improve HfO_(x)-based device performance, providing a constructive approach for the practical application of RRAM.

关键词： uniformity resistance switching field enhance layer thermal enhance layer and interface modulation

“一带一路”背景下中蒙俄经济走廊贸易潜力研究

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工业技术经济 2017年第6期36卷 111-118页

作者：温焜张旭萌南昌大学管理学院南昌330029 江西行政学院南昌330003 清华大学北京100084

在我国大力倡导"一带一路",推动全球对外经贸合作深入发展的今天,建立"中蒙俄经济走廊",充分发挥中俄蒙三国的经济互补性,挖掘三国之间的贸易潜力和合作空间,对三国的经济发展均有重要的战略意义。基于此研究背景,本文利用2002~2015年... 详细信息

在我国大力倡导"一带一路",推动全球对外经贸合作深入发展的今天,建立"中蒙俄经济走廊",充分发挥中俄蒙三国的经济互补性,挖掘三国之间的贸易潜力和合作空间,对三国的经济发展均有重要的战略意义。基于此研究背景,本文利用2002~2015年中俄对外贸易面板数据,通过引力模型分析了中蒙俄三国的贸易潜力。结果表明,近几年中俄两国之间的实际贸易额呈下降趋势,贸易增长潜力较大;中蒙两国之间的贸易虽呈现"贸易过度"的状态,但贸易额波动较大,且贸易总量较小。最后,从加强基础设施建设,增强政治、经济和文化交流以及完善边贸管理体制等3个方面对建立"中蒙俄经济走廊"提出了政策建议。

关键词：中蒙俄经济走廊引力模型自由贸易区潜力数据分析

某船舶艉轴承采用环保润滑油引起高温的原因分析

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润滑与密封 2015年第10期40卷 108-112,133页

作者：张绪猛朱汉华中国船级社江阴办事处江苏江阴214431 武汉理工大学能源与动力工程学院湖北武汉430063

针对某船舶系泊试验和航行试验期间出现的尾轴承高温现象,建立尾轴与尾轴承之间润滑的数学模型,研究尾轴转速和润滑油黏度对尾轴与尾轴承之间的油膜压力分布和承载力的影响,并分析尾轴承高温现象发生的主要原因。结果表明,采用的环保润... 详细信息

针对某船舶系泊试验和航行试验期间出现的尾轴承高温现象,建立尾轴与尾轴承之间润滑的数学模型,研究尾轴转速和润滑油黏度对尾轴与尾轴承之间的油膜压力分布和承载力的影响,并分析尾轴承高温现象发生的主要原因。结果表明,采用的环保润滑油黏度过低,船舶系泊试验和航行试验期间尾轴长时间在低转速区域运行,是导致尾轴承高温现象发生的主要原因,避免尾轴在低转速区域长时间运行和提高润滑油黏度有助于减少和避免尾轴承高温现象的发生。

关键词：环保润滑油尾轴尾轴承承载力

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七人住宅

城市建筑 2016年第4期13卷 74-81页

作者：张栩萌 mnm建筑事务所

项目名称：七人住宅业主：个人建设地点：东京都品川区设计单位：mnm建筑事务所用地面积：106 m^2建筑面积：147 m^2建筑层数：2建筑结构：钢木结构建筑材料：12 mm厚结构胶合板项目负责人：Mio Tsuneyama施工单位：N.F.C设计时间：2013... 详细信息

项目名称：七人住宅业主：个人建设地点：东京都品川区设计单位：mnm建筑事务所用地面积：106 m^2建筑面积：147 m^2建筑层数：2建筑结构：钢木结构建筑材料：12 mm厚结构胶合板项目负责人：Mio Tsuneyama施工单位：N.F.C设计时间：2013年3月~2013年5月建成时间：2013年8月图纸版权：mnm建筑事务所摄影：Sadao Hotta,Yasuaki Morinaka，

关键词：住宅建筑事务所设计时间项目负责人结构胶合板用地面积设计单位项目名称