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锥束CT散射校正的平板探测研究

福建电脑 2024年第5期40卷 65-69页

作者：罗雪莹郑州财税金融职业学院信息技术系郑州450000

为了解决锥束CT在工业CT无损检测中所产生的散射问题,从而提升图像质量,本文提出了一种基于平板探测器的锥束CT散射硬件校正方法。该方法通过在平板探测器BSA上增加散射校正单元,对原始数据进行预处理,从而有效去除散射噪声,以减少散射... 详细信息

为了解决锥束CT在工业CT无损检测中所产生的散射问题,从而提升图像质量,本文提出了一种基于平板探测器的锥束CT散射硬件校正方法。该方法通过在平板探测器BSA上增加散射校正单元,对原始数据进行预处理,从而有效去除散射噪声,以减少散射对锥束CT图像的影响。实验结果表明,该方法能够显著提高锥束CT图像的清晰度和对比度,降低散射对图像质量的影响。

关键词：平板探测器锥束CT 散射校正图像质量

知识创新视角下日本数字经济与数字技术创新发展互动机制及耦合协调研究

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科技管理研究 2024年第9期44卷 45-54页

作者：罗雪英福建商学院工商管理学院福建福州350003

立足于日本新兴产业变革发展趋势,在深入研究数字经济与数字技术创新互动机制的基础上,采用耦合协调度模型,测算日本数字经济与数字技术耦合协调发展水平及特征,以其耦合协调度指数为基础,检验并论证2011—2020年期间日本数字经济与数... 详细信息

立足于日本新兴产业变革发展趋势,在深入研究数字经济与数字技术创新互动机制的基础上,采用耦合协调度模型,测算日本数字经济与数字技术耦合协调发展水平及特征,以其耦合协调度指数为基础,检验并论证2011—2020年期间日本数字经济与数字技术创新发展从拮抗、磨合到协调,以及两者之间处于同步发展及互为滞后更替的相对发展态势,为进一步深入探讨日本数字经济和数字技术创新发展耦合协调的内在规律提供理论参考和论证方法;并针对日本现实问题,从创新人才培养体系和科学技术规划体系两个方面研究提出促进数字经济和科技创新融合发展的对策建议。

关键词：知识创新知识转化日本数字经济数字技术创新耦合研究

公共图书馆志愿者行为、满意度与持续参与意愿调查研究——以长沙图书馆为例

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图书馆理论与实践 2024年第5期 116-125页

作者：罗雪英刘泱泱湘潭大学公共管理学院

文章通过问卷调查和访谈调研法调查分析了公共图书馆志愿者的志愿服务动机、满意度以及持续参与意愿与影响因素。研究发现,现阶段志愿者的参与动机、满意度均与持续参与意愿有密切相关关系,志愿者持续参与意愿受到图书馆志愿服务管理、... 详细信息

文章通过问卷调查和访谈调研法调查分析了公共图书馆志愿者的志愿服务动机、满意度以及持续参与意愿与影响因素。研究发现,现阶段志愿者的参与动机、满意度均与持续参与意愿有密切相关关系,志愿者持续参与意愿受到图书馆志愿服务管理、内容、培训、权益、激励等因素的直接影响,并因此提出志愿引导、内容创新、培训机制、激励机制与权益保护等提升志愿者持续参与意愿的方法和策略。

关键词：公共图书馆志愿服务满意度持续参与意愿

基于用户体验的有声出版平台发展策略研究——以喜马拉雅FM为例

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数字出版研究 2024年第1期3卷 16-24页

作者：罗雪英王女娜湘潭大学公共管理学院湘潭411105

随着互联网、声音存储等新技术的发展,有声阅读成为一种阅读新趋向,各类在线音频服务不断推陈出新。研究选取喜马拉雅FM作为典型案例,从感知知识性、感知实用性、感知娱乐性、感知社交性、感知独特性、感知易用性、感知性价比、感知可靠... 详细信息

随着互联网、声音存储等新技术的发展,有声阅读成为一种阅读新趋向,各类在线音频服务不断推陈出新。研究选取喜马拉雅FM作为典型案例,从感知知识性、感知实用性、感知娱乐性、感知社交性、感知独特性、感知易用性、感知性价比、感知可靠性8个方面调研用户体验,并验证用户体验与用户持续付费阅读意愿的相关性。结合用户体验,指出有声出版平台应优化内容资源,注重差异化发展,提升互动功能并完善付费体系与售后保障,以提升用户黏性,促进有声出版平台良性可持续发展。

关键词：喜马拉雅有声出版用户体验有声阅读

The interventional effect of Polygonatum cyrtonema Hua polysaccharide on atherosclerosis in mice of different sexes

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Food Science and Human Wellness 2024年第1期13卷 370-380页

作者： Anjun Guo xueying Li Lihua Pan Qiangming Li Jianping luo Xueqiang Zha Engineering Research Centre of Bioprocess of Ministry of Education Hefei University of TechnologyHefei 230009China School of Food and Biological Engineering Hefei University of TechnologyHefei 230009China Key Laboratory of Metabolism and Regulation for Major Disease of Anhui Higher Education Institutes Hefei University of TechnologyHefei 230009China

In the present study,we investigated the intervention effects of a purified Polygonatum cyrtonema polysaccharide(PCP)on high-fat diet(HFD)-induced atherosclerosis in male and female LDLr-/-*** showed that HFD caused severe dyslipidemia,atherosclerotic lesions,oxidative damages and inflammation in male and female mice,and these effects seemed to be more pronounced in males than in ***,the above variations could be dose-dependently reversed by PCP treatment,and the intervention effects on males were greater than those on *** factor kappa-B(NF-κB),mitogen-activated protein kinase(MAPKs)and protein kinase B(Akt)are 3 pivotal signaling pathways mediating the development of ***,PCP was also found to significantly decrease the phosphorylation of p65,p38,extracellular-regulated kinase 1/2(ERK1/2)and Akt,and increase the protein expression of inhibitor of NF-κB(IκB)in the aortas of male and female mice induced by *** together,these findings indicated that PCP could be effective for the prevention of atherosclerosis,and the intervention effect of PCP on male mice was more obvious than that of female mice.

关键词： Polygonatum cyrtonema polysaccharide Anti-atherosclerosis Sex

Athens Has Gone,Beijing Is Coming

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China Today 2004年第11期53卷 10-13页

作者： ZHANG xueying & luo YUANJUN

Having attended various meetings oJcelebration and citation, Cui Dalin, deputy chief of the Chinese Sports Delegation to the Athens Olympic Games, heaves a sigh of relief as he sits in his spacious office in the Train... 详细信息

关键词：雅典奥运会北京奥运会中国体育代表团运动成绩

Alternative Role of Motif B in Template Dependent Polymerase Inhibition

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Chinese Journal of Chemical Physics 2022年第3期35卷 407-412,I0001页

作者： xueying luo Tiantian Xu Xin Gao Lu Zhang State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China University of Chinese Academy of Sciences Beijing 100049China Computer Science Program ComputerElectrical and Mathematical Sciences and Engineering(CEMSE)DivisionKing Abdullah University of Science and TechnologyThuwal 23955-6900King-dom of Saudi Arabia KAUST Computational Bioscience Research Center(CBRC) King Abdullah University of Science and TechnologyThuwal 23955-6900Kingdom of Saudi Arabia Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry Xiamen 361005China

Severe acute respiratory syndrome coronavirus 2(SARS-Co V-2) relies on the central molecular machine RNA-dependent RNA polymerase(Rd Rp) for the viral replication and transcription. Remdesivir at the template strand has been shown to effectively inhibit the RNA synthesis in SARS-Co V-2 Rd Rp by deactivating not only the complementary UTP incorporation but also the next nucleotide addition. However, the underlying molecular mechanism of the second inhibitory point remains unclear. In this work, we have performed molecular dynamics simulations and demonstrated that such inhibition has not directly acted on the nucleotide addition at the active site. Instead, the translocation of Remdesivir from +1 to-1 site is hindered thermodynamically as the posttranslocation state is less stable than the pre-translocation state due to the motif B residue G683. Moreover, another conserved residue S682 on motif B further hinders the dynamic translocation of Remdesivir due to the steric clash with the 1′-cyano substitution. Overall,our study has unveiled an alternative role of motif B in mediating the translocation when Remdesivir is present in the template strand and complemented our understanding about the inhibitory mechanisms exerted by Remdesivir on the RNA synthesis in SARS-Co V-2 Rd Rp.

关键词： SARS-CoV-2 RNA-dependent RNA polymerase Inhibitory mechanism Nu-cleotide analog Molecular dynamics simulation

Aquaporin-3 promotes proliferation and inflammation in hepatocellular carcinoma

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Genes & Diseases 2024年第4期11卷 45-48页

作者： Yao Wang Yalan Wu xueying Li Weiwei Song Fengling Zheng Xiaoying Mo Yi luo Yun Li Song Chen Huanhuan luo School of Basic Medical Sciences Guangzhou University of Chinese MedicineGuangzhouGuangdong 510006China The School of Health Guangzhou Vocational University of Science andTechnologyGuangzhouGuangdong 510555China Zhongshan Hospital of Traditional Chinese Medicine ZhongshanGuangdong 528401China The Journal Center Guangzhou University of Chinese MedicineGuangzhouGuangdong 510006China Jiangsu Vocational College of Medicine YanchengJiangsu 224005China Science and Technology Innovation Center Guangzhou University of Chinese MedicineGuangzhouGuangdong 510006China State Key Laboratory of Dampness Syndrome of Chinese Medicine GuangzhouGuangdong 510006China

Carcinogenesis is closely associated with *** have shown that lipopolysaccharides(LPS)can contribute to hepatocellular carcinoma(HC)development by inducing IL-6 and TNF-αproduction from the hepatic progenitor cells.1 Aquaporin 3(AQP3),a water channel protein,has recently been found to play a critical role in cancer-associated inflammation.

关键词： inflammation. hepatocellular inflammation

Potential-dependent insights into the origin of high ammonia yield rate on copper surface via nitrate reduction:A computational and experimental study

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Journal of Energy Chemistry 2024年第9期96卷 272-281页

作者： Yangge Guo Nannan Sun Liuxuan luo Xiaojing Cheng xueying Chen Xiaohui Yan Shuiyun Shen Junliang Zhang Institute of Fuel Cells School of Mechanical EngineeringMOE Key Laboratory of Power&Machinery EngineeringShanghai Jiao Tong UniversityShanghai 200240China Department of Chemical and Biological Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloon 999077Hong KongChina Paris Elite Institute of Technology Shanghai Jiao Tong UniversityShanghai 200240China

Focusing on revealing the origin of high ammonia yield rate on Cu via nitrate reduction(NO3RR),we herein applied constant potential method via grand-canonical density functional theory(GC-DFT)with implicit continuum solvation model to predict the reaction energetics of NO3RR on pure copper surface in alkaline *** potential-dependent mechanism on the most prevailing Cu(111)and the minor(100)and(110)facets were established,in consideration of NO_(2)_(−),NO,NH_(3),NH_(2)OH,N_(2),and N_(2)O as the main *** computational results show that the major Cu(111)is the ideal surface to produce ammonia with the highest onset potential at 0.06 V(until−0.37 V)and the highest optimal potential at−0.31 V for ammonia production without kinetic obstacles in activation energies at critical *** other minor facets,the secondary Cu(100)shows activity to ammonia from−0.03 to−0.54 V with the ideal potential at−0.50 V,which requires larger overpotential to overcome kinetic activation energy *** least Cu(110)possesses the longest potential range for ammonia yield from−0.27 to−1.12 V due to the higher adsorption coverage of nitrate,but also with higher tendency to generate di-nitrogen *** evaluations on commercial Cu/C electrocatalyst validated the accuracy of our proposed *** most influential(111)surface with highest percentage in electrocatalyst determined the trend of ammonia *** specific,the onset potential of ammonia production at 0.1 V and emergence of yield rate peak at−0.3 V in experiments precisely located in the predicted potentials on Cu(111).Four critical factors for the high ammonia yield and selectivity on Cu surface via NO3RR are summarized,including high NO3RR activity towards ammonia on the dominant Cu(111)facet,more possibilities to produce ammonia along different pathways on each facet,excellent ability for HER inhibition and suitable surface size to suppress di-nitrogen species formation at high nitrate cove

关键词： Nitrate reduction to ammonia Copper surface Density functional theory Constant electrode potential method Experimental validation