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AN EVIDENT SIDELOBE CONTROL METHOD BASED ON NSCT FOR SHIP TARGET IN SAR IMAGES

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Journal of Electronics(China) 2011年第4期28卷 419-426页

作者： Li xueying yin Dong Zhang Rong Wang Kui School of Information Science ＆ Technology University of Science and Technology of China Hefei 230027 China

Evident sidelobe on faint ship target seriously affects the accuracy of the target segmen-tation in Synthetic Aperture Radar(SAR) *** avoid this problem,a novel sidelobe control method based on NonSubsampled Contourlet Transform(NSCT) for ship targets in SAR images is presented in this *** method enhances the SAR images in NSCT domain based on target azimuth estimation and then inhibits the sidelobe directionally in NSCT high-pass frequency *** results on RADARSAT-2 images demonstrate that the proposed method can not only reduce the strong sidelobes effectively,but also enhance the intensity of the objects ***,it gives a good segmentation result on the dark ship images with strong sidelobe,and en-hances the detection rate on these targets.

关键词： Synthetic Aperture Radar(SAR) NSCT Sidelobe control Directional enhancement

IFN-γ and CD8+ T cells Contribute to Hematopoietic System Dysregulation in p40(-/-)interleukin-2Rα(-/-) mice

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IFN-γ and CD8+ T cells Contribute to Hematopoietic System D...

第十届全国免疫学学术大会

作者： Yuan Yao Liang Li xueying yin Yuqing Xie 中国科学技术大学生命科学学院肝脏免疫学实验室

Objective:We had found hematopoietic system dysregulation in p40-/-IL-2Rα-/-mice and wanted to explore the ***:leukocyte isolation,flow cytometry,bone marrow ***:Lineage-c-Kit+Sca-1+cells(LSK cells)were usually considered to contain hemopoietic stem and progenitor cells.p40-/-IL-2Rα-/-mice had increased number and percentage of bone marrow LSK cells compared with wild type ***,bone marrow LSK cells in p40-/-IL-2Rα-/-mice had high expression of MHCII molecules,indicating that these cells may act as antigen-presenting *** number and percent of erythrocytes,B cells,NK cells were reduced in the bone marrow of p40-/-IL-2Rα-/-mice,suggesting the hematopoiesis disorder of HSCs,while T cell infiltration were *** reconstitution ability of bone marrow cells from p40-/-IL-2Rα-/-mice was lower than control *** we generated IFN-γ-/-p40-/-IL-2Rα-/-mice and found these mice still contained liver inflammation but did not have a huge *** found T cell infiltration was decreased in the bone marrow of IFN-γ-/-p40-/-IL-2Rα-/-mice,and the percent and number of B cells and erythrocytes were ***,the percent,number and phenotype of bone marrow LSK cells in IFN-γ-/-p40-/-IL-2Rα-/-mice were completely recovered and close to wild type *** reconstitution ability of total bone marrow cells from IFN-γ-/-p40-/-IL-2Rα-/-mice was *** last,we generated CD8a-/-p40-/-IL-2Rα-/-mice which lacked CD8+T *** found CD8a-/-p40-/-IL-2Rα-/-mice did not develop liver inflammation with a normal percentage of B cells,NK cells and NKT *** in these mice,CD4+T cells had a less activated phenotype and reduced IFN-γ***,CD8a-/-p40-/-IL-2Rα-/-mice displayed a complete normal bone marrow hematopoietic ***:p40-/-IL-2Rα-/-mice had hemotopoietic system dysregulation mediated by IFN-γ.And in p40-/-IL-2Rα-/-mice,CD8+T cells were critical for liver inflammation and CD8+T cells derived IFN-γc

关键词： HSC MHCII IFN-γ CD8+ T

Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design

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Structure of the NS5 methyltransferase from Zika virus and i...

华东地区生物化学与分子生物学学会联合会2017年学术交流会暨安徽省生物化学与分子生物学学会理事会议

作者： Caiying Zhang Tingting Feng Yajuan Li xueying yin Weihong Zeng Xiangyu Jin Yuelong Li Feng Guo Tengchuan Jin Laboratory of Structural Immunology CAS Key Laboratory of Innate Immunity and Chronic DiseasesSchool of Life Sciences and Medical CenterUniversity of Science and Technology of China

Recent outbreak of flavivirus Zika virus(ZIKV) in America has urged the basic as well as translational studies of this important human *** nonstructural protein5(NS5) of the flavivirus has an N-terminal methyltransferase(MTase) domain which plays critical roles in viral RNA genome *** null mutant of NS5 MTase is lethal for ***,NS5 is a potential drug target for the treatment of Zika virus *** this study,we determined crystal structures of the ZIKV MTase in complex with GTP and RNA cap analogue *** analyses revealed highly conserved GTP/cap-binding pocket and S-adenosylmethionine(SAM)-binding *** conformations of the second base of the cap were identified,which suggests the flexibility of RNA *** addition,the ligand-binding pockets identified a continuous region of hotspots suitable for drug *** calculation shows that the Dengue virus inhibitor compound 10 may bind to the ZIKV MTase.

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三轴多级荷载下盐岩声波声发射特征与损伤演化规律研究

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岩石力学与工程学报 2016年第4期35卷 682-691页

作者：李浩然杨春和李佰林尹雪英石家庄铁道大学大型结构健康诊断与控制研究所河北石家庄050043 中国科学院武汉岩土力学研究所岩土力学与工程国家重点实验室湖北武汉430071 石家庄铁道大学土木工程学院河北石家庄050043 国家知识产权局专利局材料工程发明审查部北京100088

采用岩石声波、声发射一体化监测装置,系统地研究三轴多级循环荷载作用下盐岩超声波波速与声发射变化特征。结果表明:(1)岩石的超声波波速和声发射活动与应力状态呈现出良好的一致性。加载阶段,超声波波速上升,声发射活跃,卸载阶段,超... 详细信息

采用岩石声波、声发射一体化监测装置,系统地研究三轴多级循环荷载作用下盐岩超声波波速与声发射变化特征。结果表明:(1)岩石的超声波波速和声发射活动与应力状态呈现出良好的一致性。加载阶段,超声波波速上升,声发射活跃,卸载阶段,超声波波速下降,声发射平静,应力级数越高,这一特征越显著。(2)盐岩的声波、声发射特征与试验围压应力密切相关。围压水平越低,应力循环试验中岩石波速变化率越大,声发射事件数量越多;围压水平越高,岩石超声波波速变化率越小,声发射事件数量越少。五级应力荷载试验中,围压条件为5,10,15,20 MPa时盐岩的声发射事件数量分别为1 026,703,361和206个,显示了"围压致密效应"。(3)分别应用卸载模量、裂隙密度和Felicity比表征盐岩的损伤演化。结论认为:盐岩的裂隙密度和Felicity比变化与岩体承载破坏特征较为一致,可以较好地反映盐岩的损伤破裂过程,而利用卸载模量表征盐岩损伤误差较大,这是由于盐岩特殊的黏塑性变形特征造成的。

关键词：岩石力学声波声发射损伤卸载模量裂隙密度

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浅议亳州市水环境及其防治对策

环境科学与管理 2009年第6期34卷 79-81页

作者：尹学英亳州职业技术学院安徽亳州236800

从城乡居民生活用水现状、农业生产用水状况、工业生产用水状况等方面分析探讨了亳州市水环境现状,指出诸多方面存在的问题:水资源总量、地表水、地下水的开采利用及水污染,提出了防治对策:开源节流、建立节水型社会、做好中长期水资源... 详细信息

从城乡居民生活用水现状、农业生产用水状况、工业生产用水状况等方面分析探讨了亳州市水环境现状,指出诸多方面存在的问题:水资源总量、地表水、地下水的开采利用及水污染,提出了防治对策:开源节流、建立节水型社会、做好中长期水资源发展规划、防治水污染,保护水环境、加快生态工程投资力度、搞好生态恢复和补偿。

关键词：水环境现状对策

Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design

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Structure of the NS5 methyltransferase from Zika virus and i...

中国生物化学与分子生物学会第十二届全国会员代表大会暨2018年全国学术会议

作者： Caiying Zhang Tingting Feng Jinbo Cheng Yajuan Li xueying yin Weihong Zeng Xiangyu Jin Yuelong Li Feng Guo Tengchuan Jin Laboratory of Structural Immunology University of Science and Technology of China School of Medicine Stanford University

Recent outbreak of flavivirus Zika virus(ZIKV) in America has urged the basic as well as translational studies of this important human *** nonstructural protein 5(NS5) of the flavivirus has an N terminal methyltransferase(MTase) domain that plays critical roles in viral RNA genome *** null mutant of NS5 MTase is lethal for ***,NS5 is a potential drug target for the treatment of Zika virus *** this study,we determined crystal structures of the ZIKV MTase in complex with GTP and RNA cap analogue 7 *** analyses revealed highly conserved GTP/cap-binding pocket and S-adenosylmethionine(SAM)-binding *** conformations of the second base of the cap were identified,which suggests the flexibility of RNA *** addition,the ligand binding pockets identified a continuous region of hotspots suitable for drug *** calculation shows that the Dengue virus inhibitor compound 10 may bind to the ZIKV MTase.

关键词： Flavivirus family virus Zika virus Methyltransferase RNA cap Antiviral inhibitor design

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京津冀一体化背景下城市公共文化服务展望

辽宁经济职业技术学院学报.辽宁经济管理干部学院 2020年第1期 23-25页

作者：王文妤阴雪颖华北理工大学

目前,我国京津冀地区市区公共文化服务协同建设水平、发展程度与民众需求差距仍旧巨大,除城市自身发展问题外,三地深层次文化协同面临很大的挑战,且协同路径具体各异、北京城市病的恶性循环等问题都无形中加大了三地协同的困难。有关政... 详细信息

目前,我国京津冀地区市区公共文化服务协同建设水平、发展程度与民众需求差距仍旧巨大,除城市自身发展问题外,三地深层次文化协同面临很大的挑战,且协同路径具体各异、北京城市病的恶性循环等问题都无形中加大了三地协同的困难。有关政府部门要迎难而上,从发展前提、发展要素、发展结构三方面加强公共文化协同建设,最终构建出能使三地人民满意的协同服务体系。

关键词：京津冀一体化公共文化服务协同发展

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层状盐岩力学特性研究进展

力学进展 2008年第4期38卷 484-494页

作者：杨春和李银平屈丹安陈锋尹雪英中国科学院武汉岩土力学研究所岩土力学与工程国家重点实验室武汉430071 中国石油天然气股份有限公司西气东输管道公司储气库项目部北京100027

盐岩具有孔隙度低,渗透率小,损伤自恢复和塑性变形能力大等特性.本文着眼于深部盐岩能源地下储备,在简要介绍国内外盐岩力学特性研究现状基础上,着重综述了近期关于层状沉积型盐岩工程力学特性研究的进展.层状盐岩压缩试验表明泥质硬石... 详细信息

盐岩具有孔隙度低,渗透率小,损伤自恢复和塑性变形能力大等特性.本文着眼于深部盐岩能源地下储备,在简要介绍国内外盐岩力学特性研究现状基础上,着重综述了近期关于层状沉积型盐岩工程力学特性研究的进展.层状盐岩压缩试验表明泥质硬石膏夹层对盐岩体的变形和破坏特性有明显的影响,揭示了复合岩体的变形和破坏机制;层状盐岩流变试验表明层状盐岩的蠕变主要由盐岩层控制,硬夹层的存在对溶腔围岩的长期蠕变起到抑制作用;为了深入了解界面的力学特性,开展了层状盐岩直接剪切试验、间接拉伸试验和界面微观分析试验,试验表明层状盐岩体中盐岩夹层界面具有较强的黏结力,这十分有利于盐岩溶腔的密闭性和稳定性;针对特殊的层状岩体提出了复合岩体Cosserat介质扩展本构模型,并应用于层状盐岩构造中能源储库稳定性分析中.最后指出了层状盐岩工程力学特性研究中值得关注的几个重点研究方向.

关键词：层状盐岩能源地下储存压缩试验直接剪切试验界面本构关系

Conceptual Design of a Branch Beam Line at HIRFL

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近代物理研究所和兰州重离子加速器实验室年报：英文版 2003年第1期 37-37页

作者： Zhang xueying, Tang Jingyu, yin Quanming, Xu Hushan, Li Wenfei and Mao Ruishi

In the case of matching the parameters between the SFC and the SSC, a stripper was installed in between the beam transport line connecting the two accelerators. The singly charged beam from SFC will turn into multi-charged one when it goes through the stripper and only the most intensive charged beam particles will be transported to SSC. In order to collect the surplus beam particles with other charge states for experiment as well, a new branch beam line is designed behind the exit of the original BL1-B2 dipole. Fig.l shows the layout of the newly designed beam line (with the dashed components in the figure).

关键词：概念设计支波束线路加速器 HIRFL 偶极