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砂土液化后液-固相变机理的单元试验与模拟

同济大学学报（自然科学版） 2023年第1期51卷 16-22页

作者：倪雪倩叶斌中南大学土木工程学院湖南长沙410018 同济大学土木工程学院上海200092

液化后砂土流动是一个涉及液相向固相转化的过程。针对目前常规三轴加载模式在进行松砂液化后性质研究中存在局限性的现状,提出应力与应变控制相结合的加载方法,获取初始液化状态,开展液化后松散土体流态化性质研究。基于试验结果,引入... 详细信息

液化后砂土流动是一个涉及液相向固相转化的过程。针对目前常规三轴加载模式在进行松砂液化后性质研究中存在局限性的现状,提出应力与应变控制相结合的加载方法,获取初始液化状态,开展液化后松散土体流态化性质研究。基于试验结果,引入液-固相变参数,耦合流体本构与固体本构关系,建立可统一描述液化后土体应力应变关系的经验模型,实现不同密实度条件下砂土液化后液-固相变转化全过程力学行为的模拟。

关键词：液化后砂土液-固相变三轴试验本构模型

考虑多尺度孔隙耦合效应的非饱和膨胀土本构模型

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同济大学学报（自然科学版） 2023年第1期51卷 23-30页

作者：张召倪雪倩张升中南大学有色金属成矿预测与地质环境监测教育部重点实验室湖南长沙410083 中南大学地球科学与信息物理学院湖南长沙410083 中南大学土木工程学院湖南长沙410083

颗粒型膨润土材料具有颗粒间孔隙、集合体间孔隙和集合体内孔隙等多尺度孔隙结构特征,传统非饱和膨胀土双孔模型(BExM)难以准确描述其宏观力学行为。在现有BExM模型的理论框架基础上,从颗粒型膨润土材料的三重孔隙结构出发,通过双加载... 详细信息

颗粒型膨润土材料具有颗粒间孔隙、集合体间孔隙和集合体内孔隙等多尺度孔隙结构特征,传统非饱和膨胀土双孔模型(BExM)难以准确描述其宏观力学行为。在现有BExM模型的理论框架基础上,从颗粒型膨润土材料的三重孔隙结构出发,通过双加载屈服面方程和宏微观耦合效应函数表征膨润土颗粒混合物的多尺度孔隙弹塑性变形行为及其相互耦合关系。通过对比试验数据与模型模拟结果发现,模型可较好地描述非饱和颗粒型膨润土材料的膨胀力特征、膨胀变形特征以及宏微观孔隙结构演化规律。

关键词：膨润土非饱和土本构模型多尺度孔隙结构

制样方法对砂土液化力学性质影响的离散元模拟

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同济大学学报（自然科学版） 2022年第7期50卷 998-1008页

作者：叶斌宋思聪倪雪倩同济大学土木工程学院上海200092 中南大学土木工程学院湖南长沙410018

基于PFC2D软件对湿捣法和落砂法制备的砂土试样进行不排水循环剪切试验模拟,分析了砂土颗粒在动力加载过程中细观结构的变化规律。结果表明,施加荷载后,试样颗粒长轴方向在压缩侧偏向水平,拉伸侧趋向竖直,而接触法向的趋势则与之相反,... 详细信息

基于PFC2D软件对湿捣法和落砂法制备的砂土试样进行不排水循环剪切试验模拟,分析了砂土颗粒在动力加载过程中细观结构的变化规律。结果表明,施加荷载后,试样颗粒长轴方向在压缩侧偏向水平,拉伸侧趋向竖直,而接触法向的趋势则与之相反,二者的各向异性系数均逐渐上升。试样整体配位数随荷载的作用逐渐下降,液化后于0~3范围内波动。湿捣法试样比落砂法试样的各向异性程度更小,液化所需的加载循环数更多,即具有更高的抗液化强度。密实度越高,两种试样的液化强度差别越大。

关键词：砂土液化制样方法数值模拟结构特征

Grid-Connected/Islanded Switching Control Strategy for Photovoltaic Storage Hybrid Inverters Based on Modified Chimpanzee Optimization Algorithm

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Energy Engineering 2025年第1期122卷 265-284页

作者： Chao Zhou NarisuWang Fuyin ni Wenchao Zhang School of Electrical and Information Engineering Jiangsu University of TechnologyChangzhou213001China Jiangsu Key Laboratory of Power Transmission&Distribution Equipment Technology Jiangsu University of TechnologyChangzhou213001China

Uneven power distribution,transient voltage,and frequency deviations are observed in the photovoltaic storage hybrid inverter during the switching between grid-connected and island *** response to these issues,this paper proposes a grid-connected/island switching control strategy for photovoltaic storage hybrid inverters based on the modified chimpanzee optimization *** proposed strategy incorporates coupling compensation and power differentiation elements based on the traditional droop ***,it combines the angular frequency and voltage amplitude adjustments provided by the phase-locked loop-free pre-synchronization control *** pre-synchronization is achieved by regulating the virtual current to zero and aligning the photovoltaic storage hybrid inverter with the grid ***,two novel operators,learning and emotional behaviors are introduced to enhance the optimization precision of the chimpanzee *** operators ensure high-precision and high-reliability optimization of the droop control parameters for photovoltaic storage hybrid inverters.A Simulink model was constructed for simulation analysis,which validated the optimized control strategy’s ability to evenly distribute power under load *** strategy effectively mitigated transient voltage and current surges during mode ***,seamless and efficient switching between gridconnected and island modes was achieved for the photovoltaic storage hybrid *** enhanced energy utilization efficiency,in turn,offers robust technical support for grid stability.

关键词： Photovoltaic storage hybrid inverters modified chimpanzee optimization algorithm droop control seamless switching

Exosomes:the next-generation therapeutic platform for ischemic stroke

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Neural Regeneration Research 2025年第5期20卷 1221-1235页

作者： Wenjing Yin Hongyin Ma Yang Qu Jiaxin Ren Yingying Sun Zhen-ni Guo Yi Yang Stroke Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina Neuroscience Research Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina

Current therapeutic strategies for ischemic stroke fall short of the desired objective of neurological functional ***,there is an urgent need to develop new methods for the treatment of this *** are natural cell-derived vesicles that mediate signal transduction between cells under physiological and pathological *** have low immunogenicity,good stability,high delivery efficiency,and the ability to cross the blood–brain *** physiological properties of exosomes have the potential to lead to new breakthroughs in the treatment of ischemic *** rapid development of nanotechnology has advanced the application of engineered exosomes,which can effectively improve targeting ability,enhance therapeutic efficacy,and minimize the dosages *** in technology have also driven clinical translational research on *** this review,we describe the therapeutic effects of exosomes and their positive roles in current treatment strategies for ischemic stroke,including their antiinflammation,anti-apoptosis,autophagy-regulation,angiogenesis,neurogenesis,and glial scar formation reduction ***,it is worth noting that,despite their significant therapeutic potential,there remains a dearth of standardized characterization methods and efficient isolation techniques capable of producing highly purified *** optimization strategies should prioritize the exploration of suitable isolation techniques and the establishment of unified workflows to effectively harness exosomes for diagnostic or therapeutic applications in ischemic ***,our review aims to summarize our understanding of exosome-based treatment prospects in ischemic stroke and foster innovative ideas for the development of exosome-based therapies.

关键词： blood–brain barrier electroacupuncture engineering exercise exosomes ischemic stroke mesenchymal stem cells microglia neuroprotection stents

Luteolin ameliorates ulcerative colitis in mice via reducing the depletion of NCR+ILC3 through Notch signaling pathway

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Chinese Journal of Natural Medicines 2024年第11期22卷 991-1002页

作者： XIE xueqian LI Pengcheng ZHAO Meng XU Bo ZHANG Guixing WANG Qing ni Chen LUO Xia ZHOU Lian School of Pharmaceutical Sciences Guangzhou University of Chinese MedicineGuangzhou 510000China Shenzhen Bao'an Traditional Chinese Medicine Hospital Guangzhou University of Chinese MedicineShenzhen 518000China

The disorder of group 3 innate lymphoid cells(ILC3)subgroup,such as the predominance of NCR-ILC3 but the deple-tion of NCR+ILC3,is unfavorable to damaged intestinal barrier repair,which leads to the prolongations and obstinacy of ulcerative colitis(UC).Our previous studies had shown that luteolin promoted NCRILC3 differentitating into NCR+ILC3 to improving the de-pletion of NCR+ILC3 in UC mice,while the mechanism is *** article aimed to explore the underlying mechanism of luteolin enhancing the proportion NCR+*** mice model was established with 2%DSS and Notch signaling was blocked,then luteolin was used to *** results showed that the effect of luteolin on ameliorating disease symptoms in UC mice,including inhibit-ing the weight loss,reducing the pathological damage of colon mucosa,etc.,was diminished with blocking Notch signaling *** addition,luteolin increased the proportion of NCR+ILC3,NCR+MNK3 and IL-22+ILC3,decreased intestinal permeability,pro-moted mucin secretion,and promoted ZO-1 and Occludin expression,the above effect of luteolin was neutralized by Notch inhibitor *** activated the abnormally blocked Notch signaling pathway in UC *** molecular docking predicted the af-finity of luteolin for RBPJ to be-7.5 kcal·mol^(-1 )in mouse,respectively;the affinity of luteolin for Notch1 and RBPJ was respectively scored to be-6.4 kcal·mol^(-1) and-7.7 kcal·mol^(-1) homo *** results proved that luteolin is positive for enhancing the propor-tion of NCR+ILC3 via Notch signaling,and it provides a basis for targeting NCR+ILC3 for restoring intestinal barrier function to alle-viating ulcerative colitis.

关键词： Luteolin Ulcerative colitis Group 3 innate lymphoid cells Notch1 RBPJ

写人记事习作中道德说理的问题讨论与教学建议

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教学与管理 2025年第2期 51-55页

作者：倪建斌江苏省太仓市沙溪镇第一小学

写人记事习作是学生进行道德说理写作的重要载体，也是实施道德教育的重要渠道。写人记事习作中的道德说理要求学生具备一定的道德发现能力、逻辑思维水平、逻辑推理和道德推理能力。然而，小学生习作中的道德说理存在论据缺失、无关论... 详细信息

写人记事习作是学生进行道德说理写作的重要载体，也是实施道德教育的重要渠道。写人记事习作中的道德说理要求学生具备一定的道德发现能力、逻辑思维水平、逻辑推理和道德推理能力。然而，小学生习作中的道德说理存在论据缺失、无关论据、不充分论据、同质性论据、论据失真等问题。分类统计五大问题在各年级写人记事习作中的突出特征，将学生道德说理能力的发展划分为萌芽期、形塑期、思辨期和熟练期。据此，建议三年级培养例证意识，四年级学用推理方法，五年级强化情境阐述，六年级兼顾综合运用。

关键词：道德说理写人记事习作思辨性表达

Electrochemical Activation-Induced Structural Transformation in ni(OH)_(2)/Ti_(3)C_(2)T_(x)/NF Systems with Enhanced Electrochemical Performance for Hybrid Supercapacitors

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Energy & Environmental Materials 2024年第4期7卷 277-284页

作者： Chuming Xu Lu Dai Yiming Zhao Shuang Li Yapan Wu xueqian Wu Gaixia Zhang Shuhui Sun Dongsheng Li College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion MaterialsChina Three Gorges UniversityYichang 443002China Hubei Three Gorges Laboratory Yichang 443007China Department of Electrical Engineering École de Technologie Supérieure(ÉTS)MontréalQuébec H3C 1K3Canada Institut National de la Recherche Scientifique(INRS) CentreÉnergie Matériaux TélécommunicationsVarennesQuébec J3X 1P7Canada

Exploring a novel strategy for large-scale production of battery-type ni(OH)_(2)-based composites,with excellent capacitive performance,is still greatly ***,we developed a facile and cost-effective strategy to in situ grow a layer of ni(OH)_(2)/Ti_(3)C_(2)T_(x)composite on the nickel foam(NF)collector,where Ti_(3)C_(2)T_(x)is not only a conductive component,but also a catalyst that accelerates the oxidation of NF to ni(OH)_(2).Detailed analysis reveals that the crystallinity,morphology,and electronic structure of the integrated electrode can be tuned via the electrochemical activation,which is beneficial for improving electrical conductivity and redox *** expected,the integrated electrode shows a specific capacity of 1.09 C cm^(-2)at 1 mA cm^(-2)after three custom activation cycles and maintains 92.4%of the initial capacity after 1500 ***,a hybrid supercapacitor composed of ni(OH)_(2)/Ti_(3)C_(2)T_(x)/NF cathode and activated carbon anode provides an energy density of 0.1 mWh cm^(-2)at a power density of 0.97 mW cm^(-2),and excellent cycling stability with about 110%capacity retention rate after 5000 *** work would afford an economical and convenient method to steer commercial ni foam into advanced ni(OH)_(2)-based composite materials as binder-free electrodes for hybrid supercapacitors.

关键词： electrochemical activation hybrid supercapacitors ni(OH)_(2) Ti_(3)C_(2)T_(x)

以“融合式教学”推进高校思政课高质量发展的价值意蕴和实践理路

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黑龙江高教研究 2025年第1期43卷 104-111页

作者：任艳妮西安财经大学陕西西安710100

在教育数字化时代,高校思政课必然从线上线下“混合”式教学走向“融合”式教学阶段。数字化技术促发了高校思政课“融合式教学”新样态,将网络云课堂、线下专题教学课堂、翻转课堂、“克隆班”异地一同步课堂、社会大课堂等五大“融合... 详细信息

在教育数字化时代,高校思政课必然从线上线下“混合”式教学走向“融合”式教学阶段。数字化技术促发了高校思政课“融合式教学”新样态,将网络云课堂、线下专题教学课堂、翻转课堂、“克隆班”异地一同步课堂、社会大课堂等五大“融合式教学”新样态引入高校思政课改革,具有助力思政课教学向智能化、全景化、精准化与个性化迈进,促进思政课发展环境和整体生态发生转变的价值意蕴。坚持以学生为中心,差异性、个性化教学,技术服务于教学的实践原则,以内生机制保障“融合式教学”可持续发展的实践路径,不断提高思政课实效性,推进高校思政课高质量发展。

关键词：高校思政课 “融合式教学” 高质量发展实践理路