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站在巨人的肩上:从“醒脑开窍”到“疏肝调神”——谈符文彬教授对石学敏院士学术与学科专科建设经验的传承与创新

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中华针灸电子杂志 2024年第1期13卷 1-4页

作者：罗丁石学敏符文彬广州中医药大学第二临床医学院/广东省中医院 510120 广东省中医院石学敏院士工作室 510120 天津中医药大学第一附属医院 300381 国家中医针灸临床医学研究中心天津300381

国医大师石学敏院士从医60余年,创立的醒脑开窍针刺法救人无数,他在临床实践与科学研究中奉行的科学与创新原则也给针灸学科发展带来巨大动力,是推动针灸走向世界的战略医学家。符文彬教授深入领悟了石院士醒脑开窍的学术思想,将石院士... 详细信息

国医大师石学敏院士从医60余年,创立的醒脑开窍针刺法救人无数,他在临床实践与科学研究中奉行的科学与创新原则也给针灸学科发展带来巨大动力,是推动针灸走向世界的战略医学家。符文彬教授深入领悟了石院士醒脑开窍的学术思想,将石院士对“神”的认识、针刺手法量学观点、单元疗法蕴藏于“疏肝调神”整合针灸学术思想体系中。石院士在学科建设与管理、人才培养方面的经验也给符教授极大启发。符教授在多年的临床和科研工作中不断完善“疏肝调神”学术思想、创立“整合针灸”治疗抑郁障碍相关疾病以及学科、专科建设,是对石学敏院士学术与学科、专科建设经验的传承与创新,并致力于将针灸学科提升至新高度、为人类健康贡献中医针灸力量。

关键词：醒脑开窍针刺疗法继承创新

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针灸大数据发展的整体观

中华针灸电子杂志 2024年第2期13卷 45-49页

作者：李礼石学敏姚晨王舒石江伟天津中医药大学第一附属医院 300381 国家中医针灸临床医学研究中心天津300381 北京大学第一医院北京大学临床研究所100191 天津市中医药研究院附属医院 300120 国家中医药管理局脑病针刺疗法重点研究室天津300381 天津市针灸学重点实验室 300381

国家全面推进健康医疗大数据基础建设,针灸行业可顺势推动自我发展。天河灵枢大模型是针灸拥抱大数据的标志性成果。但针灸大数据的良性发展仍需要立足于针灸自身特点做好顶层设计,统筹规划并系统推进针灸大数据工程,以便加速针灸与大... 详细信息

国家全面推进健康医疗大数据基础建设,针灸行业可顺势推动自我发展。天河灵枢大模型是针灸拥抱大数据的标志性成果。但针灸大数据的良性发展仍需要立足于针灸自身特点做好顶层设计,统筹规划并系统推进针灸大数据工程,以便加速针灸与大数据的深度融合。基于此,从目标定位、支撑和应用体系、相关交叉学科建设等角度分析针灸大数据发展的需求,以便为后续制定行业规划提供参考。

关键词：针灸学大数据整体观针灸交叉学科

北京大学首钢医院发热门诊1223例患者临床资料分析

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中国卫生标准管理 2024年第15期15卷 82-85页

作者：史雪敏张丽梅宁武北京大学首钢医院感染性疾病科北京100043

目的分析发热门诊患者的流行病学特征,了解发热门诊患者发热原因和临床表现,为疾病的防治提供帮助。方法选取2022年1月—2023年1月北京大学首钢医院发热门诊收治的1223例患者的临床资料进行回顾性分析,包括患者的性别、年龄、体温、发... 详细信息

目的分析发热门诊患者的流行病学特征,了解发热门诊患者发热原因和临床表现,为疾病的防治提供帮助。方法选取2022年1月—2023年1月北京大学首钢医院发热门诊收治的1223例患者的临床资料进行回顾性分析,包括患者的性别、年龄、体温、发病时间以及血象等。结果1223例发热患者中男女比例为1.12∶1,各年龄段发热患者中有2个发热高峰,>15~25岁402例,占比32.87%;>25~35岁365例,占比29.84%。患者就诊数例最多的时间段为1月份,其次是2月份和12月份,发热患者的体温主要分布在38.0~38.9℃,共868例,占70.97%;发热类型主要为不规则发热,1091例,占比最高达到了89.21%;发热时间普遍为1~3 d。发热患者中的血象变化主要是中性粒细胞计数降低、淋巴细胞计数升高同时改变,共589例,占比48.16%;其次是单纯淋巴细胞降低,256例,占比20.93%。患者中有呼吸系统症状的有697例,占比56.99%;其次是泌尿系统症状,有306例患者,占比25.02%;病因诊断主要是呼吸系统疾病,有795例次,占比为65.00%。结论病毒感染是门诊发热患者就诊的主要原因,其中以呼吸系统疾病最为常见,中青年人群为主要发病群体,患者主要为中度、不规则发热,应加强呼吸道传染疾病知识的健康宣教,更好地防治疾病。

关键词：发热门诊发热患者流行病学呼吸道传染病发热原因临床表现

乳腺癌术后化疗初期患者支持性照顾需求及影响因素研究

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科技与健康 2024年第12期3卷 9-12页

作者：马纯华谢瑞霞姜雪宁史学敏张颖深圳职业技术大学广东深圳518055 中国医学科学院肿瘤医院深圳医院广东深圳518000

调查乳腺癌术后化疗初期患者支持性照顾需求现状,并探讨其影响因素.选取2022年11月-2023年9月深圳市某三甲医院收治的88例乳腺癌术后化疗初期患者作为研究对象,应用癌症患者支持性照顾需求量表(SCNS-SF34)调查患者的支持性照顾需求状况... 详细信息

调查乳腺癌术后化疗初期患者支持性照顾需求现状,并探讨其影响因素.选取2022年11月-2023年9月深圳市某三甲医院收治的88例乳腺癌术后化疗初期患者作为研究对象,应用癌症患者支持性照顾需求量表(SCNS-SF34)调查患者的支持性照顾需求状况,并通过单因素分析和多重线性回归分析探究患者支持性照顾需求的影响因素.结果显示,不同职业、主要照顾者及生育需求的患者SCNS-SF34总分比较差异均有统计学意义(P<0.05).研究发现,乳腺癌术后化疗初期患者支持性照顾需求较高,且大部分需求未被满足.职业、主要照顾者、生育需求均为影响乳腺癌术后化疗初期患者支持性照顾需求的独立因素.

关键词：乳腺癌术后化疗初期支持性照顾需求影响因素

Channel-Feedback-Free Transmission for Downlink FD-RAN:A Radio Map Based Complex-Valued Precoding Network Approach

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China Communications 2024年第4期21卷 10-22页

作者： Zhao Jiwei Chen Jiacheng Sun Zeyu shi Yuhang Zhou Haibo xuemin(Sherman)Shen School of Electronic Science and Engineering Nanjing UniversityNanjing 210023China College of Information Science and Electronic Engineering Zhejiang UniversityHangzhou 310058China Department of Mathematics and Theories Peng Cheng LaboratoryShenzhen 518000China Department of Electrical and Computer Engineering University of WaterlooWaterlooOntarioN2L 3G1Canada

As the demand for high-quality services proliferates,an innovative network architecture,the fully-decoupled RAN(FD-RAN),has emerged for more flexible spectrum resource utilization and lower network ***,with the decoupling of uplink base stations and downlink base stations in FDRAN,the traditional transmission mechanism,which relies on real-time channel feedback,is not suitable as the receiver is not able to feedback accurate and timely channel state information to the *** paper proposes a novel transmission scheme without relying on physical layer channel ***,we design a radio map based complex-valued precoding network(RMCPNet)model,which outputs the base station precoding based on user *** comprises multiple subnets,with each subnet responsible for extracting unique modal features from diverse input ***,the multimodal embeddings derived from these distinct subnets are integrated within the information fusion layer,culminating in a unified *** also develop a specific RMCPNet training algorithm that employs the negative spectral efficiency as the loss *** evaluate the performance of the proposed scheme on the public DeepMIMO dataset and show that RMCPNet can achieve 16%and 76%performance improvements over the conventional real-valued neural network and statistical codebook approach,respectively.

关键词： beamforming complex neural networks deep learning FD-RAN

针刺人迎穴调控RhoA/ROCK1通路改善自发性高血压大鼠血压及血管损伤的机制研究

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天津中医药 2024年第1期41卷 67-72页

作者：周诗远杨永可熊飞然陆妍赵轶文刘嘉妍史慧妍石学敏天津中医药大学第一附属医院针灸科天津300193 国家中医针灸临床医学研究中心天津300193 宁波市北仑区人民医院康复科宁波315800 河北省三河市中医院中医科廊坊065200 天津市北辰区双环邨街社区卫生服务中心中医科天津300134 天津中医药大学天津300193 天津市西青区中北镇社区卫生服务中心针灸科天津300111

[目的]基于RhoA/ROCK1通路探讨针刺人迎穴对自发性高血压大鼠血压及血管损伤的作用机制。[方法]11周龄雄性自发性高血压大鼠,随机分为模型组、针刺组和西药组,选取同周龄雄性Wistar大鼠作为正常组。针刺组和西药组分别给予针刺人迎穴和... 详细信息

[目的]基于RhoA/ROCK1通路探讨针刺人迎穴对自发性高血压大鼠血压及血管损伤的作用机制。[方法]11周龄雄性自发性高血压大鼠,随机分为模型组、针刺组和西药组,选取同周龄雄性Wistar大鼠作为正常组。针刺组和西药组分别给予针刺人迎穴和厄贝沙坦灌胃给药。观察大鼠血压变化情况,酶联免疫吸附实验(ELISA)检测血管紧张素Ⅱ(AngⅡ)和ROCK1的表达水平,逆转录聚合酶链反应(RT-PCR),蛋白免疫印迹法(Western Blot)检测内皮素-1(ET-1)和人血小板衍化生长因子-AA(PDGF-AA)的mRNA和蛋白表达水平,免疫荧光检测颈动脉组织中基质金属蛋白酶2(MMP2)和RhoA的定位及表达水平。[结果]1)与模型组比较,西药组和针刺组在治疗3周,治疗6周时的平均动脉压有降低(P<0.05)。2)与模型组比较,西药组和针刺组在治疗6周时ET-1和PDGF-AA的mRNA和蛋白的表达均降低(P<0.05)。3)与模型组比较,西药组和针刺组在治疗6周时RhoA、AngⅡ和ROCK1的蛋白表达均降低(P<0.05),针刺组在治疗6周时MMP2的蛋白表达降低(P<0.05)。4)与西药组比较,针刺组在治疗6周时AngⅡ和ROCK1的蛋白表达均降低(P<0.05)。[结论]针刺人迎穴可能通过下调颈动脉RhoA/ROCK1通路来改善自发性高血压大鼠血压及血管损伤。

关键词：人迎穴针刺血压 ET-1 AngⅡ PDGF-AA MMP2 RhoA/ROCK1通路

Resuscitating acupuncture therapy for glucose metabolism in acute cerebral infarction of basal ganglia

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Neural Regeneration Research 2010年第14期5卷 1050-1054页

作者： Pengfei Shen xuemin shi First Affiliated Hospital Tianjin University of Traditional Chinese Medicine Tianjin 300193 China

BACKGROUND： Acupuncture can improve motor function in patients with cerebral infarction, and activate brain glucose metabolism in relevant brain areas. However, the association between encephalic region activation and acupuncture, as well as the clinical significance of activation remain unclear. OBJECTIVE： Through the use of positron emission tomography-computed tomography （PET-CT）, acute cerebral infarction patients were analyzed for global cerebral metabolism, cerebral infarction focus, peripheral edema, and pyramidal tract pathway changes, which were directly related to clinical symptoms. The influence of resuscitating acupuncture on cerebral glucose metabolism was analyzed in patients with acute cerebral infarction in basal ganglia. DESIGN, TIME AND SETTNG： Randomized, controlled, clinical trials were performed from March 2007 to October 2008 at the PET-CT Center of the General Hospital of Tianjin Medical University, China. PARTICIPANTS： Twelve patients with acute basal ganglia infarction were recruited from the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, the Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin Chinese Medicine Hospital, and Affiliated Hospital of Medical College of Chinese People＇s Armed Police Force. METHODS： The cerebral infarcted patients were randomly assigned to acupuncture and control groups. In addition to routine treatment, the acupuncture group was treated by acupuncture at the main acupoints for resuscitation [Neiguan （PC 6）, Renzhong （DU 26）, and Sanyinjiao （SP 6）], while the control group received routine treatment. MAIN OUTCOME MEASURES： Before and after treatment, patients with acute cerebral infarction were evaluated for global brain, cerebral infarction focus, and surrounding edema and glucose metabolism in encephalic region of pyramidal tract conduction by 18-labeled fluorodeoxyglucose for PET-CT imaging. RESULTS： The resuscitating acupuncture th

关键词： resuscitating acupuncture positron emission tomography cerebral glucose metabolism acupuncture acute basal ganglia infarction brain injury neural regeneration

Safety and efficacy of Danqipiantan capsule for treatment of stroke: a systematic review

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Journal of Traditional Chinese Medicine 2013年第6期33卷 707-714页

作者： Jiashen Li Haizhen Zheng Xiaofeng Zhao Shu Wang xuemin shi Institute of Acupuncture and Moxibustion First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin Key Laboratory of Acupuncture and Moxibustion Science

OBJECTIVE： To evaluate the efficacy and safety of Danqipiantan capsule （DPC） for the treatment of stroke. METHODS： PubMed, China Science And Technolo- gy Journal Database, Wanfang Database, Chinese periodicals in the China National Knowledge Infra- structure, and the General Hospital of Tianjin Medi- cal University＇s Library were searched until July 2012. Randomized controlled trials （RCTs） and ob- servational studies that reported the use of DPC for treatment of stroke were selected. RESULTS： Eleven articles that included 12 RCTs, and 2 articles that included 3 observational studies were identified. A total of 2590 patients participat- ed in the studies. We found that there was a signifi-cant statistical difference between DPC treatment groups and the control groups in terms of the effec- tive rate [risk ratio （RR）, 1.14; 95% confidence inter- vals （CI）, 1.04, 1.25; P=0.01], FugI-Meyer Assessment Scale [weighted mean difference （WMD）, 9.77; 95% CI （4.84, 14.70）; P=0.00], Barthel Index [WMD=6.40; 95% CI （3.15, 9.65）], and mean flow velocity [WMD= 5.79; 95% CI （1.64, 9.94）]. There were no significant differences for The National Institutes of Health Stroke Scale [WMD=0.60; 95% CI （ - 1.09, 2.29）], vi- sual field defects [left visual field： WMD= - 203.10; 95% CI （ - 424.41, 18.21）; right visual field： WMD= - 172.60; 95% CI （ - 409.29, 64.09）] or the functional independence measure [WMD= - 7.90; 95% CI （ - 16.64, 0.84）]. Seven articles that included eight RCTs reported the safety of DPC treatment. Two ar- ticles that included three observational studies also reported beneficial effects for DPC. Because the Chinese studies were of poor methodological quali- ty, and most of the sample sizes were small, our analysis was likely affected by bias. CONCLUSION： DPC has a beneficial effect and is relatively safe when used for the treatment of stroke.

关键词： KeStroke Treatment outcome Safety Re-view Danqipiantan capsule

“Tong Guan Li Qiao” Acupuncture Therapy on Post-Stroke Dysphagia

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Chinese Medicine and Natural Products 2022年第4期2卷 174-178页

作者： Hongwen Huang Huiyan shi Xuesong Ren xuemin shi Department of Acupuncture and Moxibustion First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjinChina National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion TianjinChina Tianjin Institute of Acupuncture and Moxibustion First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjinChina Tianjin Key Laboratory of Acupuncture and Moxibustion TianjinChina

The differences between the“Tong Guan Li Qiao”acupuncture therapy and the conventional and current other acupuncture methods for poststroke dysphagia are as follows:first,it adheres to the basic idea of "Xing Nao Kai Qiao"acupuncture therapy in selecting and combining acupoints,centers on the brain,and combines the dysphagia symptoms of the mouth,tongue,and throat-related orifices with the root cause of"brain";second,thereare strictand standard requirements intheacupuncture operation,that is,manipulation *** addition to standardized twirling,lifting,and thrusting,the techniques of deep needling on the acupoints in the neck region,blood-letting puncturing at the posterior wallof the pharynx,and theneedling sensation of"like a fishbone getting stuck in the throat"are all unique.

关键词： dysphagia poststroke “Tong Guan Li Qiao” acupuncture therapy regulating spirit manipulation quantification brain