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New Material of Zhenyuanopterus(Pterosauria) from the Early Cretaceous Yixian Formation of Western Liaoning

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Acta Geologica Sinica(English Edition) 2014年第1期88卷 1-5页

作者： TENG Fangfang L Junchang WEI xuefang HSIAO Yufu Michael PITTMAN Xinghai Paleontological Museum of Dalian Institute of Geology Chinese Academy of Geological Sciences Cores and Samples Center of Land and Resources China Geological Survey Geoscience Institute Chinese Culture University Vertebrate Palaeontology Laboratory Department of Earth Sciences the University of Hong Kong

A new partial specimen of Zhenyuanopterus from the Lower Cretaceous Yixian Formation of Beipiao city, Liaoning Province is described. This specimen is slightly larger than half the size of the holotype. Although it is not complete, it provides new information on Zhenyuanopterus both in taxonomy and ontogeny： the total number of the caudal vertebrae is 15; the forelimb is more robust than the hindlimb; the growth rate of the humerus and femur is constant, and their ratio is about 1. Compared with the holotype, the scapula and coracoid grow faster than the humerus and the femur. The scapula and coracoid may slow their growth rate after a certain ontogenetic stage. The pectoral girdle, robust forelimb and weak hindlimb of the new material（XHPM1088） together with data from the holotype of Zhenyuanopterus indicate that this taxon spent less time on land than in the sky or other ecological niches such as forests and cliffs.

关键词： Boreopteridae Zhenyuanopterus ontogeny

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宜昌市点军区中药资源普查成果概述

亚太传统医药 2020年第7期16卷 165-168页

作者：陈智国杨学芳谈发明申雪阳钱特严德超邓衍清季光琼三峡大学中医医院/宜昌市中医医院湖北宜昌443000

目的:调查点军区药用植物的种类、分布、野生与栽培情况,明确该区域中药资源现状。方法:以全国第四次中药资源普查技术规范为指导,采用传统野外调查与现代技术相结合的方法,对点军区现有中药资源进行普查、统计分析。结果:该次普查共完... 详细信息

目的:调查点军区药用植物的种类、分布、野生与栽培情况,明确该区域中药资源现状。方法:以全国第四次中药资源普查技术规范为指导,采用传统野外调查与现代技术相结合的方法,对点军区现有中药资源进行普查、统计分析。结果:该次普查共完成了41个样地、205个样方套、1230个样方的调查工作,采集药用植物品种451种,涉及102科328属。其中,重点调查物种91种,涉及中药材101种。采集种子标本35种,走访调查药材种植户3户,调查栽培品种8种,完成4个中药材流通点。收集、整理民间传统经验方28个,医学古籍23本。结论:点军区中药资源物种较为丰富,柑橘类品种有较大量的种植,部分珍稀物种分布减少,应加强对中药资源的管理、保护、开发与利用。

关键词：点军区中药资源普查

经鼻高流量湿化氧疗对肺移植受者肺康复效果的影响

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中华移植杂志（电子版） 2016年第4期10卷 182-185,189页

作者：潘红黄琴红许红阳王大鹏杨学芳龚靓张毓柳微陈静瑜南京医科大学附属无锡市人民医院心肺ICU 无锡214023 南京医科大学附属无锡市人民医院肺移植科无锡214023

目的探讨应用经鼻高流量湿化氧疗(HHFNC)对肺移植受者肺康复效果的影响。方法回顾性分析2015年1月至2016年1月南京医科大学附属无锡市人民医院22例肺移植术受者,根据术后通气方案不同,将受者分为HHFNC组和持续气道正压通气(CPAP)组。观... 详细信息

目的探讨应用经鼻高流量湿化氧疗(HHFNC)对肺移植受者肺康复效果的影响。方法回顾性分析2015年1月至2016年1月南京医科大学附属无锡市人民医院22例肺移植术受者,根据术后通气方案不同,将受者分为HHFNC组和持续气道正压通气(CPAP)组。观察并比较两组受者基本资料、呼吸功能、血气分析结果及生活质量指标。采用两样本独立t检验比较两组受者年龄、APACHEⅡ等正态分布计量资料;采用配对t检验比较两组受者术后3个月和入院时SGRQ得分。采用Wilcoxon检验比较待肺时间、机械通气时间等非正态分布计量资料。P0.05)。两组受者机械通气时间、拔除人工气道时呼出潮气量及ICU住院时间差异均无统计学意义(P均>0.05)。两组受者进入ICU时、拔除经口气管插管时及转出ICU前血清p H值、脉搏血氧饱和度、动脉血二氧化碳分压、氧合指数、血清乳酸差异均无统计学意义(P均>0.05)。HHFNC组受者转出ICU前呼出潮气量及氧合指数均高于CPAP组(t=6.43、3.42,P均0.05)。结论 HHFNC可有效改善肺移植受者移植肺功能和早期生活质量。

关键词：经鼻高流量湿化氧疗康复肺移植肺功能

ARTC1-mediated VAPB ADP-ribosylation regulates calcium homeostasis

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Journal of Molecular Cell Biology 2023年第7期15卷 1-14页

作者： Xueyao Ma Mengyuan Li Yi Liu xuefang Zhang Xiaoyun yang Yun Wang Yipeng Li Jiayue Wang Xiuhua Liu Zhenzhen Yan Xiaochun Yu Chen Wu College of Life Sciences Institute of Life Sciences and Green DevelopmentHebei UniversityBaoding 071002China Department of Public Health Affiliated Hospital of Hebei UniversityBaoding 071000China Westlake Laboratory of Life Sciences and Biomedicine Hangzhou 310024China School of Life Sciences Westlake UniversityHangzhou 310024China Institute of Biology Westlake Institute for Advanced StudyHangzhou 310024China

Mono-ADP-ribosylation(MARylation)is a post-translational modification that regulates a variety of biological processes,including DNA damage repair,cell proliferation,metabolism,and stress and immune *** mammals,MARylation is mainly catalyzed by ADP-ribosyltransferases(ARTs),which consist of two groups:ART cholera toxin-like(ARTCs)and ART diphtheria toxin-like(ARTDs,also known as PARPs).The human ARTC(hARTC)family is composed of four members:two active mono-ADP-ARTs(hARTC1 and hARTC5)and two enzymatically inactive enzymes(hARTC3 and hARTC4).In this study,we systematically examined the homology,expression,and localization pattern of the hARTC family,with a particular focus on *** results showed that hARTC3 interacted with hARTC1 and promoted the enzymatic activity of hARTC1 by stabilizing *** also identified vesicle-associated membrane protein-associated protein B(VAPB)as a new target of hARTC1 and pinpointed Arg50 of VAPB as the ADP-ribosylation ***,we demonstrated that knockdown of hARTC1 impaired intracellular calcium homeostasis,highlighting the functional importance of hARTC1-mediated VAPB Arg50 ADP-ribosylation in regulating calcium *** summary,our study identified a new target of hARTC1 in the endoplasmic reticulum and suggested that ARTC1 plays a role in regulating calcium signaling.

关键词： ATRCs mono-ADP-ribosylation hARTC1 VAPB calcium homeostasis

The Effect of Netting Solidity Ratio and Inclined Angle on the Hydrodynamic Characteristics of Knotless Polyethylene Netting

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Journal of Ocean University of China 2017年第5期16卷 814-822页

作者： TANG Hao HU Fuxiang XU Liuxiong DONG Shuchuang ZHOU Cheng WANG xuefang College of Marine Sciences Shanghai Ocean University Shanghai 201306 P. R. China Faculty of Marine Science Tokyo University of Marine Science and Technology Minato Tokyo 108-8477 Japan National Engineering Research Center for Oceanic Fisheries Shanghai 201306 P. R. China Shanghai Collaborative Innovation Center for Oceanic Fisheries Shanghai 201306 P. R. China College of Fisheries Zhejiang Ocean University Zhoushan 316000 P. R. China

Knotless polyethylene(PE) netting has been widely used in aquaculture cages and fishing gears, especially in Japan. In this study, the hydrodynamic coefficient of six knotless PE netting panels with different solidity ratios were assessed in a flume tank under various attack angles of netting from 0?(parallel to flow) to 90?(perpendicular to flow) and current speeds from 40 cm s^(-1) to 130 cm s^(-1). It was found that the drag coefficient was related to Reynolds number, solidity ratio and attack angle of netting. The solidity ratio was positively related with drag coefficient for netting panel perpendicular to flow, whereas when setting the netting panel parallel to the flow the opposite result was obtained. For netting panels placed at an angle to the flow, the lift coefficient reached the maximum at an attack angle of 50? and then decreased as the attack angle further increased. The solidity ratio had a dual influence on drag coefficient of inclined netting panels. Compared to result in the literature, the normal drag coefficient of knotless PE netting measured in this study is larger than that of nylon netting or Dyneema netting.

关键词： panel fishing hydrodynamic Reynolds nylon polyethylene perpendicular Angle assessed aquaculture

多学科团队协作对乳腺癌内分泌治疗依从性的效果

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实用临床医药杂志 2018年第22期22卷 139-141,153页

作者：倪卫燕沈薇沈定玉冯艳萍王洁王伟李英杨雪芳陆亚青南京医科大学附属苏州医院苏州市立医院东区肿瘤外科五区江苏苏州215001

目的评价多学科团队协作模式对乳腺癌内分泌治疗服药依从性的影响。方法将106例符合内分泌治疗的乳腺癌患者,随机分成干预组54例和对照组52例,对照组失访2例。2组患者在首次服药时均给予常规护理教育,干预组患者同时引入多学科团队(MDT)... 详细信息

目的评价多学科团队协作模式对乳腺癌内分泌治疗服药依从性的影响。方法将106例符合内分泌治疗的乳腺癌患者,随机分成干预组54例和对照组52例,对照组失访2例。2组患者在首次服药时均给予常规护理教育,干预组患者同时引入多学科团队(MDT),评价比较在内分泌治疗期间两组患者的服药依从性。结果乳腺癌内分泌治疗服药依从性逐年下降(P <0. 05);干预组依从性及服药信念均高于对照组(P <0. 05)。结论乳腺癌内分泌治疗加入多学科团队,可提高患者的依从性,改善疗效。

关键词：乳腺癌内分泌药物治疗依从性多学科团队

WEIGHTED ESTIMATES FOR COMMUTATORS OF POTENTIAL OPERATORS ON SPACES OF HOMOGENEOUS TYPE

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Analysis in Theory and Applications 2009年第1期25卷 55-70页

作者： Wenming Li Xiaowu Yu xuefang Yan Hebei Normal University Shijiazhuang China College of Mathematics and Information Science Hebei Normal University Shijiazhuang 050016 P. R. China Department of Architectural Engineering Xingtai Vocational and Techonical College Xingtai 054000 P. R. China

We derive some strong type and weak type weighted norm estimates which re- late the commutators of potential integral operators to the corresponding maximal operators in the context of spaces of homogeneous type.

关键词： potential operator commutator BMO weight maximal operator space of homogeneous type

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新生儿危重先天性心脏病的早期干预

中国小儿急救医学 2016年第1期23卷 45-48页

作者：杨菊先王旭李守军闫军李胜利曾敏段雷雷李霞郑林鲁中原刘立伟杨雪芳国家心血管病中心中国医学科学院阜外医院小儿心脏中心PICU 北京100037

目的探讨新生儿危重先天性心脏病（先心病）的早期识别及早期干预方法。方法回顾性分析2010年1月至2014年12月阜外医院PICU收治的223例出生日龄≤30d的新生儿危重先心病病例，分析其畸形种类、临床特征及早期干预经验。结果223例先心病... 详细信息

目的探讨新生儿危重先天性心脏病（先心病）的早期识别及早期干预方法。方法回顾性分析2010年1月至2014年12月阜外医院PICU收治的223例出生日龄≤30d的新生儿危重先心病病例，分析其畸形种类、临床特征及早期干预经验。结果223例先心病患儿以完全性大动脉转位及完全性肺静脉异位引流最为常见，分别占59％（131例）和17％（39例）。首诊症状以紫绀、心脏杂音和呼吸困难最为常见，分别占91％（204例）、56％（125例）和53％（118例）。术前因严重缺氧、代谢性酸中毒及心力衰竭而急诊收住PICU抢救59例。早期干预主包括维持动脉导管开放、纠正内环境紊乱、治疗心力衰竭等，并尽早手术治疗。14例患儿未接受手术，其中4例术前死亡，另10例放弃治疗并均于出院后12d内死亡。最终接受手术209例，手术死亡9例，手术死亡率4．3％。随访3～63个月，远期死亡2例，二期解剖矫治手术2例，再次手术3例。其余术后患儿心功能正常，生长发育接近正常同龄儿童。结论必须在新生儿期进行干预的危重先心病主包括动脉导管依赖型先心病，其中以完全性大动脉转位、完全性肺静脉异位引流最为多见，如不积极手术治疗，大多于新生儿期死亡。早期识别，适当的术前处理，及时转诊和早期手术是挽救这类先心病患儿的关键。

关键词：新生儿危重先天性心脏病早期干预

Investigation on the photo-induced de-oxygenation process of myoglobin in aqueous solution by use of fluorescence spectroscopy

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Science China Chemistry 2008年第5期51卷 414-419页

作者： MA JunYan ZHENG xuefang TANG Qian MA Jing GAO DaBin HU JiHan Liaoning Key Lab of Bio-organic Chemistry Dalian University Dalian 116622China College of Bioengineering Dalian UniversityDalian 116622China

A photo-induced de-oxygenation process of myoglobin (Mb) in aqueous solution was investigated by use of fluorescence spectroscopy. The spectra are characterized by the fluorescence intensity declining gradually after each scan,and the decay of fluorescence intensity being significant in each scan,which is assigned to the release of oxygen from the opening of the heme-pockets induced by illumination. More illumination will cause more release of oxygen; if the temperature of an Mb solution is increased when it is illuminated,the rate of de-oxygenation will be higher. It was found that ligand-oxygen in Fe-porphyrin could be removed from Mb by nitrogen. This indicates that the interac-tion between oxy-Mb and other different gases can be tested by the method of fluorescence spectros-copy. In addition,fluorescence spectroscopy can be employed to probe the energy transfer between Fe-porphyrin and tryptophan or tyrosine in Mb molecules.

关键词： fluorescence spectroscopy myoglobin photo-induced de-oxygenation