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Transforming growth factor β1 is a differentially expressed candidate protein of congestive heart failure with Qi-deficiency-blood-stasis syndrome

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Journal of Traditional Chinese Medicine 2020年第2期40卷 311-316页

作者： Li Xiaoqian Huang Pinxian Wang Shijun cao xuebin He Jiancheng Research Centre on Application of Classical Prescriptions Basic Medical CollegeShanghai University of Traditional Chinese MedicineShanghai 201230China Department of Cardiology Shanghai Institute of Cardiovascular DiseasesZhongshan HospitalFudan UniversityShanghai 200032China Department of Cardiology The PLA 252 HospitalBaoding 71000China

OBJECTIVE: To investigate the role of tongue coating fluid protein in regulation of congestive heart failure(CHF) in Qi-deficiency-blood-stasis ***: We studied patients with CHF(3 patients with Qi-deficiency-blood-stasis syndrome and 3 without Qi-deficiency-blood-stasis syndrome) to investigate differentially expressed proteins. We also included a control group. A biotin label-based antibody array was used for testing tongue coating fluid samples from patients. Net-work analysis of these differentially expressed proteins was conducted using the STRING database,which can predict the relations between differentially expressed proteins and CHF with Qi-deficiency-blood-stasis ***: A total of seven differentially expressed proteins were identified, and among these, transforming growth factor β1(TGF-β1) gets a particular attention for us has drawn specific *** analysis showed a homologous relationship of TGF-β1 with bone morphogenetic protein15, which is associated with myocardial ***: Occurrence and development of CHF may result from certain DE-proteins and associated signaling pathways. TGF-β1 protein may be a candidate marker for assessing the risk of CHF in Qideficiency-blood-stasis syndrome.

关键词： Congestive heart failure Qi-deficiency blood-stasis Transforming growth factorβ1 Bone morphogenetic protein 15 Differentially expressed protein

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The early percutaneous coronary intervention in elderly patients with acute coronary syndrome

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Frontiers of Medicine 2008年第1期2卷 15-18页

作者： Xiong HUANG xuebin cao Gang ZHANG Department of Cardiology Number 252 Hospital of People’s Liberation ArmyBaoding 071000China

It is challenging to undo early percutaneous intervention(PCI)in the elderly with acute coronary syndrome(ACS).Fifteen patients older than 65 years with ACS within 24 hours of the event were admitted from April 4,2004 to December 12,*** the patients had early percutaneous coronary intervention and were followed up for 6-12 months by telephone or in the out-patient *** of the 15 patients exhibited acute myocardial infarction(AMI).Six exhib-ited unstable angina(UA).All the patients had early *** average door-to-balloon time was 78 minutes(40-110 minutes).The average PCI time was 99 minutes(68-120 minutes).Nineteen of 36 lesions in the fifteen angioplasty patients were treated and 20 stents were implanted in *** the procedures were considered *** deaths nor recurrent angina occurred in the 6-12 months of *** was shown that early PCI might be an effective and safe method to treat eld-erly patients with ACS.

关键词： acute coronary syndrome elderly percutan-eous coronary intervention coronary angiograph stent door to balloon

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Optimization of different intensities of exercise preconditioning in protecting exhausted exercise induced heart injury in rats

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Sports Medicine and Health Science 2021年第4期3卷 218-227页

作者： Zheng Ping Weijia Qiu Mei Yang Xiaoli Zhang Dongying Wang Peng Xu Ziwen Wang xuebin cao Department of Cardiology and Nephrology Hospital of the 82nd Group Army of PLABaoding071000China

This study was to optimize the exercise preconditioning(EP)intensity in protecting from exhaustive exercise-induced cardiac injury(EECI).A total of 98 male Sprague-Dawley rats were divided into 7 groups(n=14):the control group(C),the exhaustive exercise group(EE)and the EP+EE groups,which include the V10(53.0%VO_(2max)),V15(58.4%VO_(2max)),V20(67.0%VO_(2max)),V26(74.0%VO_(2max))and V30(80.0%VO_(2max))*** the C group,the other groups were subjected to treadmill *** serum contents of N terminal pro B type natriuretic peptide(NT-proBNP)and cardiac troponin I(cTn-I)were detected by the enzyme-linked immunosorbent assay method,ECG was recorded,heart function was detected by pressure volume catheter and the activities of mitochondrial electron transfer pathway(ET pathway)complexesⅠ,ⅡandⅣwere measured by high-resolution respiration *** to the EE group,the EP groups have shown decrease of NT-proBNP and cTn-I,improvement of mitochondrial respiratory function and car-diac *** to other EP groups,the V26 group has shown significant decrease of myocardial enzymes and improvement of mitochondrial *** correlation analysis showed the EP effect was proportional to EP intensity in the range of 53.0%VO_(2max)-74.0%VO_(2max).High intensity and long duration of exhaustive exercise caused cardiac injury and EP could decrease serum level of NT-proBNP and cTn-I,improve electrical derangement and the left ventricular function,and raise the activities of ET pathway complexesⅠ,ⅡandⅣ.The protection of EP on EECI was improved as the EP intensity was increased from 53.0%VO_(2max)to 74.0%VO_(2max)and when EP intensity was 74.0%VO_(2max),the effect was the most obvious among all the setting EP groups.

关键词： Exercise preconditioning Exhaustive exercise-induced cardiac injury Mitochondrial respiratory function

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倒置梯形涡流发生器与非对称超声速来流相互作用的短隔离段流动数值研究

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航空学报 2010年第3期31卷 487-492页

作者：曹学斌张堃元南京航空航天大学能源与动力学院江苏南京210016

为了有效地缩短超燃冲压发动机隔离段长度,在前期研究的等宽度平直斜楔基础上,用数值模拟的方法,研究了一种侧壁面后掠的倒置梯形涡流发生器,涡流发生器放置在隔离段进口厚附面层一侧。研究结果表明:加装倒置梯形涡流发生器后可在进出... 详细信息

为了有效地缩短超燃冲压发动机隔离段长度,在前期研究的等宽度平直斜楔基础上,用数值模拟的方法,研究了一种侧壁面后掠的倒置梯形涡流发生器,涡流发生器放置在隔离段进口厚附面层一侧。研究结果表明:加装倒置梯形涡流发生器后可在进出口压比相同的情况下,将隔离段长度减小40%左右,比等宽度平直斜楔多缩短5%;激波串长度随后掠角呈非线性变化,在一适当的后掠角下,激波串长度最小,它的总压恢复系数与等宽度平直斜楔处于同等水平。

关键词：超燃冲压发动机隔离段激波串倒置梯形涡流发生器数值仿真

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EXPERIMENTAL STUDY OF FORCED SHOCK TRAIN OSCILLATION IN ISOLATOR UNDER ASYMMETRIC INCOMING FLOW

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Transactions of Nanjing University of Aeronautics and Astronautics 2011年第1期28卷 73-80页

作者：曹学斌张堃元南京航空航天大学能源与动力学院

To analyze the response of the wall pressure fluctuation in an isolator when the shock train is subjected to a periodic motion at a low frequency,the isolator experiment is conducted in a blow-down supersonic wind tunnel at free stream Mach number of 1.98 under asymmetric incoming *** results show that：The isolator effectively isolates the periodic back pressure fluctuation from affecting upstream undisturbed flow;The wall pressure fluctuations are due to the propagation of wave fronts with the second acoustic mode,but they are subjected to an oscillating shock train in the most part of the shock oscillation region;The attenuation of wall pressure fluctuations on the lower wall with thick boundary layer accords with the exponential law,but it fluctuates on the upper wall with thin boundary layer in the shock oscillation region.

关键词： engines shock waves pressure distribution isolator

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Battery State of Health Estimation Based on Multiple Linear Regression by Particle Swarm Optimization

Battery State of Health Estimation Based on Multiple Linear ...

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第40届中国控制会议

作者： Peng Huang Pingwei Gu xuebin cao Kun Jiang Bin Duan Chenghui Zhang School of Control Science and Engineering Shandong University

State of health of battery is crucial for electric vehicles, which has been widely studied through many different methods where incremental capacity analysis（ICA） is a common method for battery state of health estimation. However,previous methods are difficult to find suitable feature information from multiple features to make the estimation result better,especially considering that the ICA curves of different batteries have different peak numbers and positions. In this paper, in order to acquire accurate peak coordinates, the Gaussian filtering is used to make the incremental capacity（IC） curve smoother, and then the method that using multiple linear regression by particle swarm optimization（PSO） is proposed to solve the problems mentioned above. Compared with the traditional multiple linear regression, multiple linear regression by particle swarm optimization selects the most appropriate variables to improve the accuracy of estimation. In the experiment, a group of peak data of series module of battery is selected for linear regression to get the optimal variables and corresponding parameters, and then the corresponding verification is carried out by using the data of six different aging states of another series module of battery. The experimental results show that except the sixth group of the state of health estimation error is 2.09%, the estimation error of the remaining five groups is less than 2%, so this method has high accuracy and adaptability for series module of battery.

关键词： battery particle swarm optimization multiple linear regression state of health Gaussian filtering

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A Fast Capacity Estimation Approach for Retired Lithium-ion Batteries

A Fast Capacity Estimation Approach for Retired Lithium-ion ...

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第40届中国控制会议

作者： xuebin cao Zhongkai Zhou Bin Duan Pingwei Gu Yunlong Shang Chenghui Zhang School of Control Science and Engineering Shandong University

Capacity is one of the most critical parameters of lithium-ion batteries（LIBs）. Retired batteries generally also have 70%-80% of the nominal capacity, so it can bring considerable benefits through echelon use. However, the existing methods cannot simultaneously meet the capacity estimation accuracy and efficiency required for large-scale retired batteries. So this may lead to costing excessive time and energy. To solve the above problems, a fast and accurate capacity evaluation method based on support vector machine（SVM） is proposed in this paper. And the parameters（penalty coefficient and kernel function width） of the SVM model are optimized by the particle swarm optimization（PSO）. In order to expand the scope of application,capacity evaluation models in three different SOC are established. The inputs of the model are sampling voltages selected from the featured charging curve at three cases, and the output is the battery capacity. Experimental results demonstrate that the maximum error in the first case is less than 3.02%, and the errors in the other two cases are 1.88% and 1.97% respectively.

关键词： retired batteries capacity estimation support vector machine(SVM) particle swarm optimization(PSO)

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基于模糊神经网络的目标识别模型

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战术导弹技术 2007年第5期 90-92,96页

作者：曹学斌刘进忙空军工程大学导弹学院陕西三原713800

目标识别是地空导弹武器系统决策中的关键技术.针对目标特性,提出了一种基于模糊技术的BP神经网络的目标识别模型.从传感器中提取目标特性,经过模型处理,可以较好地实现目标的类型识别.

关键词：目标识别模糊技术 BP神经网络

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Long-distance Tele-robotic-assisted Percutaneous Coronary Intervention:A Case Report of First-inpatient in China

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Cardiology Discovery 2024年第3期4卷 245-249页

作者： Kai Xu xuebin cao Haiwei Liu Shenghua Zhou Zhaochuan Liu Xianghe Wang Quanmin Jing Yaling Han Department of Cardiology General Hospital for Northern Theater CommandShengyangLiaoning 110016China Department of Cardiology Hospital of82nd Group ArmyPeople’s Liberation ArmyBaodingHebei 071033China Department of Cardiology Second Xiangya Hospital of Central South UniversityChangshaHunan 410012China

Robotic-assisted percutaneous coronary intervention(R-PCI)is an innovative way of performing percutaneous coronary intervention(PCI)whereby the operator can manipulate coronary intraluminal guidewires and catheter devices by using remotely controlled *** tele-R-PCI from a remote location via fifth generation network communication technology has never been reported in China;however,if this were possible,the technique could be used to treat many patients with coronary artery disease who would otherwise not have the opportunity of *** case of a 73-year-old male patient with coronary artery disease who underwent successful tele-R-PCI at 800 km from the operators is *** long-distance teleR-PCI in patients with coronary artery disease is feasible with predictably successful outcomes when reliable network connectivity and local cardiac catheterization facilities are present.

关键词： Percutaneous coronary intervention Robotic Remote Percutaneous coronary intervention Fifth generation network communication

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课外阅读在小学语文作文教学中的重要性及应用

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家长 2020年第23期 150-151页

作者：曹学斌甘肃省定西市渭源县上湾学区常家坪小学

小学作文在小学语文教学中占据很大的比例,拥有丰富的阅读储备是写好小学语文作文的关键因素。本文通过分析当代小学生的阅读现状,指出了课外阅读对小学语文作文教学的重要性,并据此提出了相应的措施以及教学方法。

关键词：小学语文作文课外阅读重要性应用

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