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Relationship between postoperative rehabilitation style, gastrointestinal function, and inflammatory factor levels in children with intussusception

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2640-2648页

作者： xue-yan wei Hong-Chang Huo Xin Li Su-Li Sun Jun Zhang Department of Outpatient Shijiazhuang Maternal and Child Health HospitalShijiazhuang 050090Hebei ProvinceChina Department of Pediatric Surgery Shijiazhuang Maternal and Child Health HospitalShijiazhuang 050090Hebei ProvinceChina Department of Nursing Shijiazhuang Maternal and Child Health HospitalShijiazhuang 050090Hebei ProvinceChina

BACKGROUND Intussusception occurs in children and progresses *** not treated in time,it may lead to secondary complications such as intestinal perforation,which affect the quality of life and health of *** is the most common clinical treatment and has a good ***,the postoperative prognosis of children with intussusception has a correlation with the postoperative rehabilitation ***,in this study,we explored the relationship between postopera-tive rehabilitation,gastrointestinal function,and the expression of inflammatory factors in children with *** medical records of 18 children who were admitted to our hospital for intussusception surgery between October 2022 and May 2024 were retrospectively *** patients were divided into the routine nursing group(n=6)and rehabilitation training group(n=12)according to the postoperative rehabilitation *** general data,gastrointestinal function,and inflammatory factor levels of the two groups were statistically *** correlation analysis of gastrointestinal function,inflammatory factors,and postoperative rehabil-itation was *** We found no significant intergroup differences in sex,age,or disease course(P>0.05).The times to first defecation,bowel sound recovery,and anal exhaust were shorter and inflammatory factor levels were lower in the rehabilitation training group than in the routine nursing group(P<0.05).Pearson correlation analysis showed that gastrin and motilin levels were positively correlated with postoperative rehabilitation(P<0.05).Interleukin(IL)-2,IL-4,IL-6,IL-10,high-sensitivity C-reactive protein,and tumor necrosis factor-αlevels were negatively correlated with postoperative rehabilitation(P<0.05).Gastrointestinal function was positively correlated(P<0.05),and levels of inflammatory factors were negatively correlated with postoperative recovery time(P<0.05).CONCLUSION We found a positive correlation between gastrointe

关键词： Children with intussusception Postoperative rehabilitation mode Gastrointestinal function Inflammatory factors

IL-21 acts as a promising therapeutic target in systemic lupus erythematosus by regulating plasma cell differentiation

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Cellular & Molecular Immunology 2015年第1期12卷 31-39页

作者： Xiao-Mei Deng Shang-xue yan wei wei Institute of Clinical Pharmacology of Anhui Medical University Key Laboratory of Anti-inflammatory and Immune Medicine Ministry of Education HefeiChina

Plasma cells, which secrete auto-antibodies, are considered to be the arch-criminal of autoimmune diseases such as systemic lupus erythematosus, but there are many cytokines involved in inducing the differentiation of B-cell subsets into plasma cells. Here, we emphasize IL-21, which has emerged as the most potent inducer of plasma cell differentiation. In this review, we focused on the promoting effects of IL-21 on plasma cell differentiation and discuss how these effects contribute to B cell-mediated autoimmune disease.

关键词： Bcl-6 Blimp-1 IL-21 plasma cell systemic lupus erythematosus

Six-month results of a biodegradable polymer and rapamycin-coating stent for coronary artery disease

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Journal of Geriatric Cardiology 2006年第2期3卷 67-70页

作者： Yuxiao ZHANG Caiyi LU Qiao xue Peng LIU wei yan Rui CHEN Institute of Geriatric Cardiology General Hospital of Chinese PLA Beijing 100853 China Institute of Geriatric Cardiology General Hospital of Chinese PLA Beijing 100853 China Institute of Geriatric Cardiology General Hospital of Chinese PLA Beijing 100853 China Institute of Geriatric Cardiology General Hospital of Chinese PLA Beijing 100853 China Institute of Geriatric Cardiology General Hospital of Chinese PLA Beijing 100853 China Institute of Geriatric Cardiology General Hospital of Chinese PLA Beijing 100853 China

Objective To assess the safety and efficacy of a novel biodegradable polymer and rapamycin-coating stent, the EXCEL stent, in the treatment of coronary artery disease (CAD), as compared with the CypherTM stent. Methods In this prospective, non-randomized study, 60 consecutive patients with symptomatic CAD received either an EXCEL stent (n=32), or a CypherTM stent(n=28),according to their respective treatment intention. Follow-up angiography was performed at a mean of 180±40 days. The primary endpoint of the study was the occurrence of a major adverse cardiac event (MACE), including death, myocardial infarction, or target-vessel revascularization during the 6 months after stenting. The secondary end points included the in-stent late luminal loss (LLL), percentage of in-stent stenosis of the luminal diameter, and the rate of restenosis (luminal narrowing of 50 percent or more) at 6 months. Results There were no significant differences between the two groups in baseline characteristics, including the distribution of target vessel and lesion types. During the follow up period of 6 months, there were no occurrences of MACE in either group. Twenty-seven patients(84%) in the EXCEL group and 10 (36 %) in the CypherTM group underwent quantitative coronary angiography at 6 months. For these patients, no restenosis occurred, and there were no differences in the in-stent stenosis of the luminal diameter (5.98±5.52% vs 5.21 ±6.3%,P＞0.05) and the LLL (-0.02±0.09 mm vs -0.01±0.07 mm, P＞0.05). Conclusions Compared with the CypherTM stent, the EXCEL Stent with biodegradable polymer and rapamycin-coating showed similar efficacy in the prevention of neointimal proliferation, restenosis, and associated clinical events in CAD patients.

关键词： coronary artery disease stent, rapamycin biodegradable polymer

Numerical simulation of dendrite growth in Ni-based superalloy casting during directional solidification process

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Transactions of Nonferrous Metals Society of China 2019年第2期29卷 338-348页

作者： xue-wei yan Xiong GUO yan-ling LIU Xiu-fang GONG Qing-yan XU Bai-cheng LIU Key Laboratory for Advanced Materials Processing Technology Ministry of EducationSchool of Materials Science and EngineeringTsinghua UniversityBeijing 100084China Dongfang Turbine Co. Ltd.Deyang 618000China Long-life High Temperature Materials State Key Laboratory Deyang 618000China

An understanding of dendrite growth is required in order to improve the properties of castings. For this reason, cellular automaton-finite difference(CA-FD) method was used to investigate the dendrite growth during directional solidification(DS)process. The solute diffusion model combined with macro temperature field model was established for predicting the dendrite growth behavior. Model validation was performed by the DS experiment, and the cooling curves and grain structures obtained by the experiment presented a reasonable agreement with the simulation results. The competitive growth of dendrites was also simulated by the proposed model, and the competitive behavior of dendrites with different misalignment angles was also discussed in ***, 3D dendrites growth was also investigated by experiment and simulation, and both were in good accordance. The influence on dendrites growth of initial nucleus was investigated by three simulation cases, and the results showed that the initial nuclei just had an effect on the initial growth stage of columnar dendrites, but had little influence on the final dendritic morphology and the primary dendrite arm spacing.

关键词： numerical simulation directional solidification dendrite growth Ni-based superalloy

Situation, problems and approaches to medical English teaching

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Sino-US English Teaching 2010年第2期7卷 7-11页

作者： CAI Yu WANG Yuan PANG wei xue yan Foreign Language Department Anhui Medical University Hefei 230032 China

With a brief review of the ESP （English for Special Purpose） teaching in Medical Schools over the past 30 years, this paper elaborates on the changes and situation of English teaching and leaming in some Medical Schools. Through a survey which throws light on the importance of ESP, the paper analyzes the problems facing Medical Schools, such as materials suitable for medical students who want to cultivate their ability in listening, speaking, reading, writing and translating in their own field and teachers who are supposed to be qualified for medical English teaching, and then discusses the top priorities in these Medical Schools and examines what has been done and will be done in order to work out practicable approaches to meet the requirements of medical students.

关键词： ESP in Medical School situation and consequence approaches to problems

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中国背景下农民工创业成长的过程机制

心理科学进展 2012年第2期20卷 197-207页

作者：韦雪艳江南大学人文学院教育系无锡214122

农民工创业研究伴随着寻找创业沃土的渴求而兴起,有创业意向,选择正确商业概念来采取行动策略并发展有价值的商业机会使企业成长对任何一个创业者至关重要,也与国家目前弘扬以创业带动就业的时代主题一致。相比国外创业研究的盛行,国内... 详细信息

农民工创业研究伴随着寻找创业沃土的渴求而兴起,有创业意向,选择正确商业概念来采取行动策略并发展有价值的商业机会使企业成长对任何一个创业者至关重要,也与国家目前弘扬以创业带动就业的时代主题一致。相比国外创业研究的盛行,国内对该主题的本土化实证研究尚待加强。经过对以往研究的总结分析,结合本土化研究取向,本研究拟采用半结构化访谈、配对成组问卷的现场研究和实验室模拟研究方法,以行动策略与社会网络理论为基础,探索变革背景下中国农民工创业成功成长的过程机制,具体包括三方面研究:(1)从特质因素探讨农民工创业主动性、动态能力和创业效能感对创业意向、机会识别和行动策略的影响;(2)从社会网络和社会资本因素探讨农民工社会资本特征对设定目标、采取行动策略、识别机会的影响,即,社会资本如何影响农民工的创业成长;(3)农民工创业行动策略对创业绩效的影响。

关键词：农民工创业成长社会网络行动理论本土化

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胡适《章实斋先生年谱》编纂考

安徽史学 2017年第1期 143-150页

作者：薛艳伟南开大学历史学院天津300350

《章实斋先生年谱》是胡适在史学方面的代表作。胡适在创作《章谱》前后,围绕章学诚研究与日本学者内藤湖南和青木正儿进行了密切的学术互动。胡适试图通过该谱训练和展示自己的考据功力,并展现他在年谱学方面的"用意与方法"。1921年的... 详细信息

《章实斋先生年谱》是胡适在史学方面的代表作。胡适在创作《章谱》前后,围绕章学诚研究与日本学者内藤湖南和青木正儿进行了密切的学术互动。胡适试图通过该谱训练和展示自己的考据功力,并展现他在年谱学方面的"用意与方法"。1921年的胡适因参加各种社会、学术活动非常繁忙,但他还是千方百计地抽出时间完成《章谱》的写作任务。该谱革新了传统的年谱体例,创立了新的典范,提供了一个示范的样板,因而得到不少学者的仿效。

关键词：胡适《章实斋先生年谱》内藤湖南青木正儿余英时

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

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Neural Regeneration Research 2025年第1期20卷 209-223页

作者： Shi-yan Sun Lingyun Nie Jing Zhang xue Fang Hongmei Luo Chuanhai Fu Zhiyi wei Ai-Hui Tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

基于广义出行费用的城市综合交通方式优势出行距离研究

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交通运输系统工程与信息 2018年第4期18卷 25-31页

作者：范琪王炜华雪东魏雪延梁鸣璋东南大学城市智能交通江苏省重点实验室南京210096 东南大学现代城市交通技术协同创新中心南京210096 东南大学交通学院南京210096

为研究城市综合交通网络结构,帮助决策者合理配置城市交通资源,本文研究了城市综合交通网络中基于广义出行费用的各交通方式优势出行距离概率密度曲线.分析居民出行的广义出行费用(即交通方式的服务水平,包括出行时间和票价等)可以确定... 详细信息

为研究城市综合交通网络结构,帮助决策者合理配置城市交通资源,本文研究了城市综合交通网络中基于广义出行费用的各交通方式优势出行距离概率密度曲线.分析居民出行的广义出行费用(即交通方式的服务水平,包括出行时间和票价等)可以确定城市中常见交通方式出行所需的平均花费水平,从而构建出同一出行网络中不同交通方式优势出行距离的概率密度曲线,对概率密度曲线进行分析和拟合可以得到固定形式的基于广义出行费用的城市综合交通方式优势出行距离概率密度模型.最后,以南京市为例进行实证分析.

关键词：城市交通综合交通运输客运方式选择优势运距概率密度曲线