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Efficacy of Huangma Ding or autologous platelet-rich gel for the diabetic lower extremity arterial disease patients with foot ulcers

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World Journal of Diabetes 2024年第5期15卷 923-934页

作者： xue-Qin Wang Dan-Lan Pu Wei-Ling Leng Xiao-Tian Lei Jiang juan Zou La Ding Yao Jia-Zhuang Xi Li Jian Teng Miao Qi-Nan Wu Endocrinology Department The People’s Hospital of Yubei District of Chongqing CityChongqing 401120China Department of Endocrinology Chongqing Yubei District People’s HospitalChongqing 400030China Endocrinology Department The First Affiliated Hospital of the Army Medical UniversityChongqing 400038China Endocrinology and Nephrology Department Chongqing University Cancer Hospital and Chongqing Cancer Institute and Chongqing Cancer HospitalChongqing 400016China Department of Endocrinology Dazu Hospital of Chongqing Medical UniversityThe People’s Hospital of DazuChongqing 402360China

BACKGROUND Diabetes foot is one of the most serious complications of diabetes and an important cause of death and disability,traditional treatment has poor efficacy and there is an urgent need to develop a practical treatment *** To investigate whether Huangma Ding or autologous platelet-rich gel(APG)treatment would benefit diabetic lower extremity arterial disease(LEAD)patients with foot *** A total of 155 diabetic LEAD patients with foot ulcers were enrolled and divided into three groups:Group A(62 patients;basal treatment),Group B(38 patients;basal treatment and APG),and Group C(55 patients;basal treatment and Huangma Ding).All patients underwent routine follow-up visits for six *** follow-up,we calculated the changes in all variables from baseline and determined the differences between groups and the relationships between *** The infection status of the three groups before treatment was the ***(PCT)improved after APG and Huangma Ding treatment more than after traditional treatment and was significantly greater in Group C than in Group *** regression analysis revealed that PCT was positively correlated with total amputation,primary amputation,and minor amputation *** ankle-brachial pressure and the transcutaneous oxygen pressure in Groups B and C were greater than those in Group *** major amputation rate,minor amputation rate,and total amputation times in Groups B and C were lower than those in Group *** Our research indicated that diabetic foot ulcers(DFUs)lead to major amputation,minor amputation,and total amputation through local infection and poor microcirculation and *** Ding and APG were effective attreating *** clinical efficacy of Huangma Ding was better than that of autologous platelet gel,which may be related to the better control of local infection by Huangma *** finding suggested that in patients with DFUs combined with coinfection,controll

关键词： Diabetic foot ulcer Huangma Ding Autologous platelet-rich gel Ankle-brachial index Transcutaneous oxygen partial pressure

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From Perspective of Hippocampal Plasticity:Function of Antidepressant Chinese Medicine Xiaoyaosan

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Chinese Journal of Integrative Medicine 2024年第8期30卷 747-758页

作者： ZHANG Wu-jing GUO Ze-xuan WANG Yi-di FANG shao-yi WAN Chun-miao YU Xiao-long GUO Xiao-fang CHEN Yue-yue ZHOU Xuan HUANG Jun-qing LI Xiao-juan CHEN Jia-xu FAN Li-li Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine School of Traditional Chinese MedicineJinan UniversityGuangzhou510632China

The hippocampus is one of the most commonly studied brain regions in the context of *** volume of the hippocampus is significantly reduced in patients with depression,which severely disrupts hippocampal ***,antidepressant therapies that target hippocampal neuroplasticity have not been identified as *** medicine(CM)can slow the progression of depression,potentially by modulating hippocampal ***(XYS)is a CM formula that has been clinically used for the treatment of *** is known to protect Gan(Liver)and Pi(Spleen)function,and may exert its antidepressant effects by regulating hippocampal *** this review,we have summarized the association between depression and aberrant hippocampal ***,we have discussed the researches published in the last 30 years on the effects of XYS on hippocampal neuroplasticity in order to elucidate the possible mechanisms underlying its therapeutic action against *** results of this review can aid future research on XYS for the treatment of depression.

关键词： depression hippocampal neuroplasticity Xiaoyaosan Chinese medicine

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论习近平文化思想的核心要义

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浙江工商大学学报 2024年第3期 5-15页

作者：袁银传邵雪武汉大学马克思主义学院

“推进中国特色社会主义文化建设、建设中华民族现代文明”是习近平文化思想的核心要义，展现了以中国之答回应当代人类文明之问的理论旨趣和用发展着的马克思主义文化理论引领人类文化前进方向的理论创新逻辑。习近平文化思想从人类文... 详细信息

“推进中国特色社会主义文化建设、建设中华民族现代文明”是习近平文化思想的核心要义，展现了以中国之答回应当代人类文明之问的理论旨趣和用发展着的马克思主义文化理论引领人类文化前进方向的理论创新逻辑。习近平文化思想从人类文明发展的高度把握文化建设问题，在“推进中国特色社会主义文化建设”与“建设中华民族现代文明”内在融通中引领人类文明正确前进方向、凝聚当代中国价值共识、推进社会主义文化理论创新发展。以马克思主义文化理论为基础、立足实践推进马克思主义文化理论创新、用中华优秀传统文化充实马克思主义的文化生命、破除西方中心主义的文明观，是对习近平文化思想核心要义的理论把握。深刻把握习近平文化思想的核心要义，有助于深化认识习近平文化思想的理论视野、理论品格和世界历史意义。

关键词：习近平文化思想核心要义文化强国建设中华民族现代文明

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Effect of continuous nursing on treatment compliance and side effect management of coronary heart disease

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World Journal of Clinical Cases 2024年第19期12卷 3701-3707页

作者： juan Wei Bai-Wen-Xian Li shao-Jie Han Hong-Jie Zhuang Wen-Hong Cao Department of Cardiology The First Affiliated Hospital of Hebei North UniversityZhangjiakou 750061Hebei ProvinceChina

BACKGROUND There are relatively few studies on continuing care of coronary heart disease(CHD),and its research value needs to be further *** To investigate the effect of continuous nursing on treatment compliance and side effect management in patients with *** This is a retrospective study with patients from January 2021 to *** study was divided into two groups with 30 participants in each ***-rating anxiety scale(SAS)and Self-rating depression scale(SDS)were used to assess patients'anxiety and depression,and medical coping questionnaire was used to assess patients'coping *** pelvic floor dysfunction questionnaire(PFDI-20)was used to assess the status of pelvic floor function,including bladder symptoms,intestinal symptoms,and pelvic *** SAS score decreased from 57.33±3.01before treatment to 41.33±3.42 after treatment,SDS score decreased from 50.40±1.45 to 39.47±*** decrease of these two indexes was statistically significant(P<0.05).PFDI-20 scores decreased from the mean 16.83±1.72 before treatment to 10.47±1.3the mean after treatment,which was statistically significant(P<0.05).CONCLUSION The results of this study indicate that pioneering research in continuous care of CHD has a positive impact on improving patients'treatment compliance,reducing anxiety and depression levels,and improving coping styles and pelvic floor functional status.

关键词： Coronary heart disease Continuing care Treatment compliance Anxiety and depression Coping style Pelvic floor function status Pioneering study

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Cation effects in electrocatalytic reduction reactions:Recent advances

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Chinese Journal of Catalysis 2024年第8期63卷 16-32页

作者： Qinghui Ren Liang Xu Mengyu Lv Zhiyuan Zhang Zhenhua Li Mingfei shao xue Duan State Key Laboratory of Chemical Resource Engineering College of ChemistryBeijing University of Chemical TechnologyBeijing 100029China College of Chemical Engineering Beijing University of Chemical TechnologyBeijing 100029China Quzhou Institute for Innovation in Resource Chemical Engineering Quzhou 324000ZhejiangChina

Electrocatalytic reduction reactions,powered by clean energy sources such as solar energy and wind,offer a sustainable method for converting inexpensive feedstocks(e.g.,CO_(2),N2/NOx,organics,and O_(2))into high-value-added chemicals or *** design and modification of electrocatalysts have been widely implemented to improve their performance in these ***,bottle-necks are encountered,making it challenging to further improve performance through catalyst development ***,cations in the electrolyte have emerged as critical factors for tuning both the activity and product selectivity of reduction *** review summarizes recent advances in understanding the role of cation effects in electrocatalytic reduction ***,we introduce the mechanisms underlying cation *** then provide a comprehensive overview of their application in electroreduction *** techniques and theoretical calcula-tion methods for studying cation effects are also ***,we address remaining challeng-es and future perspectives in this *** hope that this review offers fundamental insights and design guidance for utilizing cation effects,thereby advancing their development.

关键词： Electrocatalysis Reduction reaction Cation effect Mechanism Application

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澜沧江流域近55年来极端气温时空变化特征

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云南师范大学学报（自然科学版） 2017年第2期37卷 64-72页

作者：王学李少娟裴顺强吴巩胜云南财经大学城市与环境学院云南昆明650221 中国气象局公共气象服务中心北京100081

基于澜沧江流域33个气象站点1960-2014年的日最高气温、日最低气温、日平均气温资料,选用极端冷指标、极端暖指标等9个极端气温指数,对澜沧江流域近55年来极端气温的时空变化特征进行分析.结果表明:(1)极端冷指标在空间上存在差异性,受... 详细信息

基于澜沧江流域33个气象站点1960-2014年的日最高气温、日最低气温、日平均气温资料,选用极端冷指标、极端暖指标等9个极端气温指数,对澜沧江流域近55年来极端气温的时空变化特征进行分析.结果表明:(1)极端冷指标在空间上存在差异性,受地形地势影响,各项指标的空间分布整体呈现明显的纬向分布特征,其中,年平均最低气温、冷日阈值、冷夜阈值整体呈现北低南高,冰冻日数、霜冻日数与之相对应,呈现相反的北高南低的分布趋势;(2)极端暖指标的空间分布也具有明显的纬向分布特征.暖日阈值、暖夜阈值的空间分布与年平均最高气温的空间分布相一致,整体呈现北低南高;(3)澜沧江流域的冷夜阈值、冷日阈值和年平均最低气温均呈上升趋势,霜冻日数、冰冻日数呈下降趋势;而极端暖指标均呈上升趋势,说明近55年来澜沧江流域的高温事件正在增加,而霜冻与冰冻等低温事件正在逐年减少.

关键词：极端气温变化时空分布特征澜沧江流域

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Continuous age-and sex-specific reference ranges of liver enzymes in Chinese children and application in pediatric non-alcoholic fatty liver disease

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World Journal of Pediatrics 2024年第9期20卷 949-956页

作者： Zhao-Yuan Wu Si-Wei Chi Liu-Jian Ouyang Xiao-Qin Xu Jing-Nan Chen Bing-Han Jin Rahim Ullah xue-Lian Zhou Ke Huang Guan-Ping Dong Zhe-Ming Li Ying Shen Jie shao Yan Ni Jun-Fen Fu Qiang Shu Wei Wu Department of Endocrinology Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child Health3333 Binsheng RoadHangzhou310051China Department of Data and Information Children’s HospitalZhejiang University School of MedicineHangzhouChina Department of Child Health Care Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhouChina Department of Thoracic&Cardiovascular Surgery Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthNational Children’s Regional Medical Center3333 Binsheng RoadHangzhou310051China

Background Alanine aminotransferase(ALT)is widely used to screen patients with hepatic ***,the current reference ranges(<50 U/L)were developed by laboratories and have not been validated in populations with a large number of healthy *** This study collected venous blood and anthropometric data from a total of 13,287 healthy children aged 3 months to 18 years who underwent routine physical examinations in the Department of Pediatric *** applied the least mean square algorithm to establish age-and sex-related reference percentiles of serum levels of *** validation,we recruited 4276 children and adolescents with obesity/overweight who underwent evaluation and metabolic tests in the *** receiver operating characteristic curves,we determined age-and sex-specific upper limit percentiles of liver enzymes for fatty liver *** This study revealed a significant correlation between serum transaminase levels and age and sex(P<0.01).These transaminase levels exhibited age-and sex-specific *** individuals in the non-alcoholic fatty liver disease(NAFLD)cohort,elevated ALT levels displayed a positive association with clinical markers of disease severity,including homeostatic model assessment of insulin resistance,waist-hip ratio,and serum uric acid levels(P<0.01).According to the receiver operating characteristic curves,ALT levels at the 92.58th percentile for boys and the 92.07th percentile for girls yielded the highest accuracy and *** This study provides age-and sex-specific reference ranges for ALT,aspartate aminotransferase,andγ-glutamyltransferase in Chinese children and adolescents,making it the largest population study to ***,the study establishes a precise upper limit for ALT levels,facilitating their use in NAFLD screening.

关键词： Alanine aminotransferase Childhood Fatty liver diseases

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Exploring biomedical applications with silver and copper nanotechnology

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cMat 2024年第2期1卷 1-8页

作者： xue-Qian Li shao-Lei Xie Hui-Dong Xie Meng-Qi Shen Zhen-Hui Ma Hu Liu Key Laboratory of Green and High-end Utilization of Salt Lake Resources Qinghai Institute of Salt LakesChinese Academy of SciencesXiningChina School of Chemistry and Chemical Engineering Xi'an University of Architecture and TechnologyXi'anChina Lenfest Center for Sustainable Energy Columbia UniversityNew YorkUSA Department of Physics Beijing Technology and Business UniversityBeijingChina

The overuse and misuse of antibiotics has accelerated the emergence of bacterial resistance,making the treatment of common infections increasingly difficult and *** has led to a rise in infection rates,worsened patient outcomes,and heightened mortality *** response,researchers have been exploring new antimicrobial strategies,with metal nanomaterials of controllable shape and size gaining significant attention for their unique antibacterial *** these,silver(Ag)and copper(Cu)nanomaterials(NMs)stand out for their wide applications in biomedical materials due to their effective antimicrobial mecha-nisms when used as *** and Cu NMs,exemplifying metal biomaterials,showcase broad-spectrum antibacterial capabilities,durable antimicrobial effects,low toxicity,and reduced likelihood of developing drug ***,they are known to promote angiogenesis,making them exceptionally suitable for biomaterial *** review underscores the significance of Ag and Cu NMs in the biomedical sector,detailing their applications and the promising role they play as medical *** aim is to encourage further exploration and utilization of Ag and Cu NMs in biomaterials and industrial production sectors.

关键词： Ag nanomaterials biomaterial cell-biological activity Cu nanomaterials metal nanomaterials

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户籍地房价对人口流动的阻滞效应研究——基于CLDS2016调查数据的分析

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中央财经大学学报 2024年第9期 93-103页

作者：樊学瑞邵禾欣兰州大学经济学院伦敦大学学院

高房价和人口流动是萦绕中国城镇化进程中的两个重要问题,也是城镇化后半程实现城镇化高质量发展亟需关注的政策着力点。本文从户籍地房价入手,利用2016年CLDS调查数据,使用Probit模型从个体层面考察了户籍地房价对流动人口跨省流动决... 详细信息

高房价和人口流动是萦绕中国城镇化进程中的两个重要问题,也是城镇化后半程实现城镇化高质量发展亟需关注的政策着力点。本文从户籍地房价入手,利用2016年CLDS调查数据,使用Probit模型从个体层面考察了户籍地房价对流动人口跨省流动决策的影响。研究发现,户籍地房价越高,流动人口跨省流动的意愿越低,户籍地房价对流动人口跨省流动决策存在阻滞效应。相较于沿海区域和城市人口,户籍地高房价对内陆区域和农村户籍人口的跨省流动阻滞效应更强。根据研究结果,本文得出应当从优化房地产市场调控政策、扩大流动人口公共服务覆盖面、提升农村转移人口技能素质三个角度提高城镇化发展质量。

关键词：户籍地房价人口流动跨省流动阻滞效应

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人工智能技术对城市经济韧性的影响研究

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软科学 2024年第6期38卷 13-19,60页

作者：刘家旗薛飞茹少峰西安科技大学管理学院西安710699 中国社会科学院大学应用经济学院北京102488 西北大学经济管理学院西安710127

基于2011-2021年中国288个地级市数据,构建面板平滑转移模型,考察人工智能技术对城市经济韧性的非线性影响。研究发现:人工智能技术与城市经济韧性之间呈U型关系。就影响机制而言,人工智能技术一方面通过增加创业活跃度提升城市经济韧性... 详细信息

基于2011-2021年中国288个地级市数据,构建面板平滑转移模型,考察人工智能技术对城市经济韧性的非线性影响。研究发现:人工智能技术与城市经济韧性之间呈U型关系。就影响机制而言,人工智能技术一方面通过增加创业活跃度提升城市经济韧性,另一方面通过加剧数字鸿沟降低城市经济韧性;从时间动态特征来看,人工智能技术对城市经济韧性的影响效应随时间变化呈现先抑制后促进的走势;异质性结果表明,人工智能技术对京津冀、长三角等城市群,高经济发展水平地区和大数据综合试验区试点城市经济韧性存在显著提升作用。而在北部湾、哈长等城市群以及低经济发展水平地区和非大数据综合试验区城市,人工智能技术反而削弱了城市经济韧性。

关键词：人工智能城市经济韧性创业活跃度数字鸿沟 PSTR模型

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