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The source of lithium in Lakkor Co Salt Lake on qinghai-Tibet Plateau,China:evidence from hydrochemical characteristics and boron isotope

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Acta Geochimica 2024年第5期43卷 933-946页

作者： Zheng Yan Li Bin Kai Li Mao-Yong He xue qin wen Jiang Di Zhou Department of Geoscience and Technology Taiyuan University of TechnologyYingzexi StreetTaiyuan 030024Shanxi ProvinceChina State Key Laboratory of Loess and Quaternary Geology Institute of Earth EnvironmentChinese Academy of SciencesXi’an 710061China qinghai Provincial Key Laboratory of Geology and Environment of Salt Lakes Qinghai Institute of Salt LakesChinese Academy of SciencesXining 810008QinghaiChina School of Earth Science and Resources Chang’an UniversityXi’an 710000ShaanxiChina qinghai Normal University Academy of Plateau Science and SustainabilityXining 810016China

The availability of lithium resources is of great significance for the development of modern technologies,as well as for civil and military *** qinghai-Tibet Plateau is a region known for its abundance of lithium-rich salt ***,the specific origin of lithium in these lakes is still unknown,which hinders the advancement of the lithium resource business in this *** research this issue,this study involved the collection of 20 samples from Lakkor Co Salt Lake on qinghai-Tibet Plateau,encompassing samples of surface brine,cold springs,fresh lakes,and recharge *** composition of anions and cations in these samples was ***,the analysis extensivelyutilizedthePiperthree-linediagram,Gibbs model,and ion proportion *** findings of this study indicate that as the moves from the recharge water system to salt lake,there is a transition in water type from strong carbonate to moderate carbonate and weak carbonate,as well as Na *** research based on a similar source of both lithium and boron,utilized ion correlation analysis and boron isotope study in the Lakkor Co area,and analyzed the source and transporting process of *** main origin of lithium in Lakkor Co is the dissolution of lithiumrich rocks,recharge water systems,and deep hydrothermal *** findings are highly significant in enhancing the foundational data of lithium-rich brine resources in the qinghai-Tibet Plateau and are beneficial for assessing the future development of such deposits.

关键词： Lithium Hydrochemical Li-rich Salt lake Boron isotope

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The microRNA miR-184 regulates the CYP303A1 transcript level to control molting of Locusta migratoria

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Insect Science 2021年第4期28卷 941-951页

作者： Yan-Li Wang Li-Xian Wu Hui-Yong Li xue-qin wen En-Bo Ma Kun-Yan Zhu Jian-Zhen Zhang Research Institute of Applied Biology Shanxi UniversityTaiyuanShanxiChina College of Life Science Shanxi UniversityTaiyuanShanxiChina Department of Entomology Kansas State UniversityManhattanKSUSA

Cytochrome P450 monooxygenases(CYPs)play essential physiological functions in ***303A1 is highly conserved in insect species studied to date,and shows an indispensable role for adult eclosion in both Locusta migratoria and Drosophila ***,how CYP303A1 is regulated to control insect developmental processes remains *** this study,we discovered functional binding sites for miR-184 in the coding sequence of *** luciferase reporter assay showed that miR-184 could target LmCYP303A1 and regulate its expression in ***,overexpression of miR-184 through microinjection of agomir to locusts reduced the transcripts of LmCYP303A1 and led to abnormal molting,which is similar to the phenotype of silencing LmCYP303A1 by direct injection of dsLmCYP303A1 to ***,down-regulation of miR-184 by injection of antagomir increased the LmCYP303A1 transcript and caused molting *** findings suggested that miR-184 could target LmCYP303A1 to regulate the molting process in ***,which might be considered as a novel target for pest control.

关键词： CYP303A1 gene regulation insect molting Locusta migratoria miR-184

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《爱佐与爱莎》中颜色与方位的对应表述探究

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贵州民族研究 2014年第12期35卷 111-115页

作者：薛钦文中央民族大学少数民族语言文学系北京100081

在彝文献《爱佐与爱莎》中,多处出现颜色与方位有序对应的句子,这种近乎固定的表述模式也见诸于其他一些彝文文献中。从此类文献中归纳总结颜色与方位的对应模式,并从文化视角进行分析,认为文本中这种整齐的对应叙述体现了彝族人民对客... 详细信息

在彝文献《爱佐与爱莎》中,多处出现颜色与方位有序对应的句子,这种近乎固定的表述模式也见诸于其他一些彝文文献中。从此类文献中归纳总结颜色与方位的对应模式,并从文化视角进行分析,认为文本中这种整齐的对应叙述体现了彝族人民对客观世界的认知和观照,折射出彝族人民的哲学、宗教观念和文艺创作理念,是彝文化的一种外在表征。

关键词：彝族文献颜色方位

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An efficient quantum proactive incremental learning algorithm

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 49-57页

作者： Lingxiao Li Jing Li Yanqi Song Sujuan qin Qiaoyan wen Fei Gao State Key Laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications School of Cyberspace Security Beijing University of Posts and Telecommunications

In scenarios where a large amount of data needs to be learned, incremental learning can make full use of old knowledge, significantly reduce the computational cost of the overall learning process, and maintain high performance. In this paper, taking the MaxCut problem as our example, we introduce the idea of incremental learning into quantum computing, and propose a Quantum Proactive Incremental Learning algorithm(QPIL). Instead of a one-off training of quantum circuit, QPIL contains a multi-phase training on gradually-increased subgraphs of all vertices, proactively reducing large-scale problems to smaller ones to solve in steps, providing an efficient solution for MaxCut. Specifically, some vertices and corresponding edges are randomly selected for training to obtain optimized parameters of the quantum circuit at first. Then, in each incremental phase, the remaining vertices and corresponding edges are gradually added and the parameters obtained from the previous phase are reused in the parameter initialization of the current phase. We perform experiments on 120 different small-scale graphs, and it shows that QPIL performs superior to prevalent quantum and classical baselines in terms of approximation ratio(AR), time cost, anti-forgetting, and solving stability. In particular, QPIL's AR surpasses 20% of mainstream quantum baselines, and the time cost is less than 1/5 of them. The idea of QPIL is expected to inspire efficient and high-quality solutions in large-scale Max Cut and other combinatorial optimization problems.

关键词： variational quantum algorithm incremental learning multi-phase training MaxCut quantum computing

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Engineered Cancer Nanovaccines:A New Frontier in Cancer Therapy

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Nano-Micro Letters 2025年第2期17卷 134-168页

作者： Yijie Wang Congrui Liu Chao Fang Qiuxia Peng wen qin xuebing Yan Kun Zhang Central Laboratory and Department of Medical Ultrasound Sichuan Academy of Medical SciencesSichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaNo.32West Second SectionFirst Ring RoadChengdu 610072People’s Republic of China Department of Stomatology and Central Laboratory School of MedicineShanghai Tenth People’s HospitalTongji UniversityNO.301 Yan‑Chang‑Zhong RoadShanghai 200072People’s Republic of China Jiangsu Provincial Innovation and Practice Base for Postdoctors Suining People’s HospitalAffiliated Hospital of Xuzhou Medical UniversityNo.2Bayi West RoadSuiningXu Zhou 221000Jiangsu ProvincePeople’s Republic of China

Vaccinations are essential for preventing and treating disease,especially cancer nanovaccines,which have gained considerable interest recently for their strong anti-tumor immune *** can prompt the immune system to generate antibodies and activate various immune cells,leading to a response against tumor tissues and reducing the negative effects and recurrence risks of traditional chemotherapy and *** enhance the flexibility and targeting of vaccines,nanovaccines utilize nanotechnology to encapsulate or carry antigens at the nanoscale level,enabling more controlled and precise drug delivery to enhance immune *** nanovaccines function by encapsulating tumor-specific antigens or tumor-associated antigens within *** small size of these nanomaterials allows for precise targeting of T cells,dendritic cells,or cancer cells,thereby eliciting a more potent anti-tumor *** this paper,we focus on the classification of carriers for cancer nanovaccines,the roles of different target cells,and clinically tested cancer nanovaccines,discussing strategies for effectively inducing cytotoxic T lymphocytes responses and optimizing antigen presentation,while also looking ahead to the translational challenges of moving from animal experiments to clinical trials.

关键词： Cancer nanovaccines Immunotherapy Nanobiotechnology Immune targets Signaling pathway

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中国汞的地球化学空间分布特征

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地球化学 2007年第6期36卷 621-627页

作者：文雪琴迟清华长安大学地球科学与国土资源学院中国地质科学院地球物理地球化学勘查研究所应用地球化学开放实验室河北廊坊065000 中国地质科学院地球物理地球化学勘查研究所应用地球化学开放实验室

20世纪80年代以来中国积累了岩石、土壤和水系沉积物中的大量可靠的汞分析数据和图件,为分析汞的地球化学空间分布特征提供了依据。从空间分布上看,从中国北部到南部,从西部到东部,土壤和水系沉积物中汞的含量背景值逐渐增高,汞在以干... 详细信息

20世纪80年代以来中国积累了岩石、土壤和水系沉积物中的大量可靠的汞分析数据和图件,为分析汞的地球化学空间分布特征提供了依据。从空间分布上看,从中国北部到南部,从西部到东部,土壤和水系沉积物中汞的含量背景值逐渐增高,汞在以干旱荒漠区、半干旱荒漠区、黄土地区和高寒山区为主的西部和北部呈低背景,在东部的森林沼泽区和半湿润低山丘陵区为中等背景,在南部的湿润低山丘陵区、热带雨林区和高山峡谷区为高背景,尤其在以云南东南部、贵州、广西西部、湖南西部岩溶区为中心的低温成矿域内,无论岩石、土壤还是水系沉积物,汞含量背景值达到最高。一般情况下,岩石、土壤和水系沉积物之间的汞含量具有继承性,在地理空间分布上呈明显的对应关系,并且土壤和水系沉积物之间的汞含量具有相近性,土壤和水系沉积物较岩石更为富集汞。

关键词：汞背景值元素空间分布岩石土壤沉积物中国

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COMPARISON OF SHORT- AND LONG-TERM OUTCOMES BETWEEN CYPHER AND TAXUS DRUG-ELUTING STENTS FOR IN-STENT RESTENOSIS

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Chinese Medical Sciences Journal 2007年第1期22卷 5-8页

作者： Ji-lin Chen Yue-jin Yang Shu-bin Qiao Min Yao xue-wen qin Bo Xu Hai-bo Liu Yong-jian Wu Jin-qing Yuan Jue Chen Shi-jie You Jun Dai Jian-jun Li Run-lin Gao Center for Diagnosis ＆ Treatment of Coronary Heart Disease Cardiovascular Institute and Fuwai Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100037

Objective To compare the short- and long-term clinical outcomes between sirolimus-eluting stent （ Cypher stent） and paclitaxel-eluting stent （TAXUS stent） in patients with in-stent restenosis （ISR） lesions of the coronary arteries. Methods From December 2002 to March 2005, 253 patients with ISR lesions of the coronary arteries were selected and divided into two groups. Cypher group （152 cases） was treated with Cypher or Cypher Select stents, and TAXUS group （101 cases） with TAXUS stents. A total of 262 ISR lesions in these patients were treated with 308 drog-eluring stents （DESs）, including 176 Cypher or Cypher Select stents and 132 TAXUS stents. All patients were followed up for 10 months. Procedure success rates of DES implantation in both groups were observed. Major adverse cardiac events （MACE） rates in hospital and at 10 months follow-up, as well as in-DES restenosis observed using coronary angiography at follow-up were compared between two groups. Results Success rate of DES implantation was 100% in both groups. No significant difference in MACE rate during hospitalization was found between the two groups. However, at 10 months follow-up, MACE rate was higher in TAXUS group than in Cypher group （ 16.00% vs. 6.67%, P =0. 031 ）. As for coronary angiography at 10 months follow-up, we observed an increasing tendency of in-DES restenosis rate in TAXUS group compared with Cypher group （29.41% vs. 14.04%, P=0.075）. Conclusions Cypher and TAXUS DESs both have good short- and long-term outcomes in treating ISR. Cypher DES proved better long-term clinical outcome than TAXUS DES.

关键词： in-stent restenosis drug-eluting stent outcome

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Profound thrombocytopenia induced by clopidogrel with a prior history of long-term safe administration

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World Journal of Cardiology 2010年第6期2卷 160-162页

作者： Yuan-Lin Guo Jian-Jun Li Jin-qing Yuan xue-wen qin Xin Zheng Chao-Wei Mu Yi-Hong Hua Yuan-Lin Guo Jian-Jun Li Jin-Qing Yuan Xue-Wen Qin Xin Zheng Chao-Wei Mu Yi-Hong Hua Department of Cardiology Fu Wai Hospital Chinese Academy of Medical Sciences Peking Union Medical College Beijing 100037 China.

Clopidogrel has shown an excellent safety,tolerability and efficacy ever since its ***,here we report a rare case with profound thrombocytopenia following clopidogrel administration previously safely exposed to this same *** reminds us that thrombocytopenia might be induced by clopidogrel even with a prior,safe history of long-term administration.

关键词： Clopidogrel Thrombocytopenia Coronary artery disease Stent

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金属活动态提取法及其在黑龙江大兴安岭森林覆盖区的应用

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地球科学与环境学报 2006年第4期28卷 43-48页

作者：文雪琴长安大学地球科学与国土资源学院

介绍了金属活动态的理论依据、成晕机制及提取方法,并应用金属活动态提取法在大兴安岭原始森林覆盖区对已知矿进行试验研究,发现在高寒森林覆盖区,利用金的水提取态异常强度低,异常不明显,而金的粘土结合态和铁锰氧化物结合态异常清晰... 详细信息

介绍了金属活动态的理论依据、成晕机制及提取方法,并应用金属活动态提取法在大兴安岭原始森林覆盖区对已知矿进行试验研究,发现在高寒森林覆盖区,利用金的水提取态异常强度低,异常不明显,而金的粘土结合态和铁锰氧化物结合态异常清晰地反映在矿体上方,异常强度居于中等。金的有机质结合态异常值虽然高,但容易受有机质在样品中颗粒大小等因素的影响而使异常出现多个峰值。总之,利用金属活动态提取法在高寒森林覆盖区进行找矿可以快速有效地确定异常,但要注意排除过多有机杂质在提取过程中的影响。

关键词：金属活动态高寒森林覆盖区有机质金矿大兴安岭黑龙江

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太原西山矿区杜儿坪井田夹矸地球化学特征及其地质意义

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矿物岩石地球化学通报 2015年第4期34卷 763-771页

作者：杨亚丽文雪琴曾凡桂太原理工大学地球科学与工程系太原030024

为探明太原西山矿区杜儿坪井田夹矸的地球化学特征及其地质成因,用X射线衍射分析(XRD)、电感耦合等离子体质谱(ICP-MS)、电感耦合等离子体发射光谱(ICP-OES)、氢化物-原子荧光光谱(HG-AFS)、发射光谱法(ES)等方法对杜儿坪井田2号、3号和... 详细信息

为探明太原西山矿区杜儿坪井田夹矸的地球化学特征及其地质成因,用X射线衍射分析(XRD)、电感耦合等离子体质谱(ICP-MS)、电感耦合等离子体发射光谱(ICP-OES)、氢化物-原子荧光光谱(HG-AFS)、发射光谱法(ES)等方法对杜儿坪井田2号、3号和8号煤层夹矸进行了矿物学和地球化学特征研究。结果发现2号、3号和8号煤层夹矸中矿物以高岭石、石英为主;与华北上地壳相比,杜儿坪夹矸中富集有害微量元素Cd、Se、Mo、Pb、Be、Cu、Th和U,山西组夹矸中有害元素含量大于太原组(除Mo、Pb和U);所有夹矸样品中Li、Ga的含量超过了工业品位,其工业利用价值值得关注;山西组夹矸稀土元素总含量高于太原组夹矸,所有夹矸稀土元素分配模式反映其与陆源碎屑关系密切;通过分析得到该区夹矸形成期间的陆源碎屑主要来自北部的花岗岩;太原组夹矸形成过程受海水影响;稀土元素与Al和Si等造岩矿物的聚类分析表明,夹矸中稀土元素主要赋存于高岭石等黏土矿物中。

关键词：煤夹矸微量元素稀土元素地球化学特征地质意义

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