检索结果-南通市图书馆

A novel machine learning-assisted clinical diagnosis support model for early identification of pancreatic injuries in patients with blunt abdominal trauma:a cross-national study

引用

Emergency and Critical Care Medicine 2023年第4期3卷 142-148页

作者： Sai Huang xuan Zhang Bo Yang Yue Teng Li Mao Lili Wang Jing Wang xuan zhou Li Chen Yuan Yao Cong Feng Department of Hematology Fifth Medical Center of Chinese PLA General HospitalBeijingChina National Clinical Research Center of Geriatric Diseases Chinese PLA General HospitalBeijingChina Hospital Management Institute Medical Innovation Research DepartmentChinese PLA General HospitalBeijingChina Department of General Thoracic Surgery First Medical Center of Chinese PLA General HospitalBeijingChina Department of Emergency Medicine General Hospital of Northern Theatre CommandShenyangLiaoningChina Department of General Medicine First Medical Center of Chinese PLA General HospitalBeijingChina Department of Emergency Hainan Hospital of Chinese PLA General HospitalSanyaHainanChina Department of General Medicine Hainan Hospital of Chinese PLA General HospitalSanyaHainanChina Department of Emergency First Medical Center of Chinese PLA General HospitalBeijingChina State Key Laboratory of Kidney Diseases National Clinical Research Center of Kidney DiseasesGeneral Hospital of People’s Liberation ArmyBeijingChina.

Background:The recognition of pancreatic injury in blunt abdominal trauma is often severely delayed in clinical *** aim of this study was to develop a machine learning model to support clinical diagnosis for early detection of abdominal ***:We retrospectively analyzed of a large intensive care unit database(Medical Information Mart for Intensive Care[MIMIC]-IV)for model development and internal validation of the model,and performed outer validation based on a cross-national data *** regres-sion was used to develop three models(PI-12,PI-12-2,and PI-24).Univariate and multivariate analyses were used to determine variables in each *** primary outcome was early detection of a pancreatic injury of any grade in patients with blunt abdominal trauma in the first 24 hours after ***:The incidence of pancreatic injuries was 5.56%(n=18)and 6.06%(n=6)in the development(n=324)and internal validation(n=99)cohorts,*** validation cohort showed good discrimination with an area under the receiver operator characteristic curve(AUC)value of 0.84(95%confidence interval[CI]:0.71–0.96)for ***-24 had the best AUC,specificity,and positive predictive value(PPV)of all models,and thus it was chosen as the final model to support clinical ***-24 performed well in the outer validation cohort with an AUC value of 0.82(95%CI:0.65–0.98),specificity of 0.97(95%CI:0.91–1.00),and PPV of 0.67(95%CI:0.00–1.00).Conclusion:A novel machine learning-based model was developed to support clinical diagnosis to detect pancreatic injuries in patients with blunt abdominal trauma at an early stage.

关键词： Abdominal trauma Clinical diagnosis support model Machine learning Pancreatic injury

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering classification recycling of spent lithium-ion batteries through pretreatment:a comprehensive review from laboratory to scale-up application

引用

Rare Metals 2024年第3期43卷 915-941页

作者： Shu-xuan Yan You-zhou Jiang Xiang-Ping Chen Lu Yuan Ting-Ting Min Yu Cao Wan-Li Peng Tao zhou Hunan Provincial Key Laboratory of Chemical Power Sources College of Chemistry and Chemical EngineeringCentral South UniversityChangsha 410083China College of Chemistry and Chemical Engineering Hunan Normal UniversityChangsha 410083China School of Public Policy and Management Tsinghua UniversityBeijing 100084China China Nonferrous Metal Industry's Foreign Engineering and Construction Co. LtdBeijing 100029China

The lithium-ion batteries(LIBs)have been widely equipped in electric/hybrid electric vehicles(EVs/HEVs)and the portable electronics due to their excellent electrochemical ***,a large number of retired LIBs that consist of toxic substances(e.g.,heavy metals,electrolytes)and valuable metals(e.g.,Li,Co)will inevitably flow into the waste stream,and their incineration or landfill treatment will cause severe risks to ecosystem and human *** sustainable and efficient treatment or recycling of valuable resources from spent LIBs should be fully recognized for environmental and resource *** one of the most important processes for spent LIBs recycling,the pretreatment is an indispensable step,which is directly related to the subsequent metal extraction and separation *** considerable progresses have been made regarding the pretreatment technologies,there are few summarized reports concerning critical processes of spent LIBs recycling,especially combination of currently available recycling technologies with industrialized applications during ***,comprehensive review of the current prevailing pretreatment technologies in laboratory to existing scale-up applications is quite necessary to reveal cutting-edge development in the field of *** this review,the current pretreatment technologies are systematically categorized and introduced,along with critical *** review focused on the various options for pretreatment processes itself,instead of general spent LIBs recycling technologies without the focused topics that have been sophisticatedly reviewed by previous ***,the deactivation,discharge,dismantling,separation,liberation of active material and electrolyte treatment have been summarized with the in-depth discussion of the technology development and current status of each ***,current states of industrial development are also reviewed and discussed for the development of

关键词： Spent lithium-ion batteries(LIBs) Recycling Pretreatment Valuable metals Cutting-edge technologies Industrialized application

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clinical significance and potential application of cuproptosis-related genes in gastric cancer

引用

World Journal of Gastrointestinal Oncology 2023年第7期15卷 1200-1214页

作者： Jia-Ning Yan Li-Hua Guo Dan-Ping Zhu Guo-Liang Ye Yong-Fu Shao Han-xuan zhou Department of Gastroenterology The First Affiliated Hospital of Ningbo UniversityNingbo 315000Zhejiang ProvinceChina Department of Pharmacy Yinzhou Integrated TCM and Western Medicine HospitalNingbo 315000Zhejiang ProvinceChina

BACKGROUND Worldwide,gastric cancer(GC)is a common lethal solid malignancy with a poor *** is a novel type of cell death mediated by protein lipoylation and may be related to GC *** To offer new insights to predict GC prognosis and provide multiple therapeutic targets related to cuproptosis-related genes(CRGs)for future *** We collected data from several public data portals,systematically estimated the expression level and prognostic values of CRGs in GC samples,and investigated related mechanisms using public databases and *** Our results revealed that FDX1,LIAS,and MTF1 were differentially expressed in GC samples and exhibited important prognostic significance in The Cancer Genome Atlas(TCGA)*** constructed a nomogram model for overall survival and disease-specific survival prediction and validated it via calibration ***-nistically,immune cell infiltration and DNA methylation prominently affected the survival time of GC ***,protein-protein interaction network,KEGG pathway and gene ontology enrichment analyses demonstrated that FDX1,LIAS,MTF1 and related proteins play key roles in the tricarboxylic acid cycle and *** Expression Omnibus database validation showed that the expression levels of FDX1,LIAS,and MTF1 were consistent with those in the TCGA *** 10 perturbagens has been filtered CONCLUSION In conclusion,FDX1,LIAS,and MTF1 could serve as potential prognostic biomarkers for GC patients and provide novel targets for immunotarget therapy.

关键词： Cuproptosis Prognosis Gastric cancer Biomarker Nomogram Bioinformatics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

预应力型钢组合支撑在深基坑中的应用分析

引用

建筑机械化 2024年第4期45卷 65-67页

作者：杨宏飞吕瑞清周璇赵蓉左臣禄童泽东中国建筑一局(集团)有限公司北京100161

以杭钱塘工出【2021】32号光环新网(杭州)数字经济科创中心项目为例,从结构受力特点、经济性、安全性和工期等方面,说明型钢组合支撑在深基坑支护中的适用性,并对基坑监测数据进行分析,证明本施工方法可有效控制基坑变形,确保基坑安全。

关键词：深基坑预应力、型钢组合支撑钢筋混凝土支撑绿色施工

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

老年灼口综合征患者口腔健康相关生活质量影响因素的多元线性回归分析

引用

中华老年口腔医学杂志 2024年第3期22卷 157-162页

作者：卢成辉周璇黄泽凡江新香杨成龙唐国瑶桂林医学院附属口腔医院口腔黏膜病科桂林541004 上海交通大学医学院附属新华医院口腔科上海200092 上海交通大学医学院附属新华医院康复医学科上海200092

目的探讨老年灼口综合征(burning mouth syndrome,BMS)患者口腔健康相关生活质量的影响因素。方法选取2022年12月至2023年11月期间于桂林医学院附属口腔医院和上海交通大学医学院附属新华医院就诊的85例老年BMS患者做横断面研究,采用口... 详细信息

目的探讨老年灼口综合征(burning mouth syndrome,BMS)患者口腔健康相关生活质量的影响因素。方法选取2022年12月至2023年11月期间于桂林医学院附属口腔医院和上海交通大学医学院附属新华医院就诊的85例老年BMS患者做横断面研究,采用口腔健康影响程度量表(oral health impact profile-14,OHIP-14)评价患者口腔健康相关生活质量,采用病例记录表收集患者的一般人口学信息,并分析疼痛、焦虑、抑郁、睡眠障碍与口腔健康相关生活质量的相关性,经多元线性回归分析筛选影响患者口腔健康相关生活质量的危险因素。结果85例BMS患者的OHIP-14评分为10.36±6.58分。有全身伴随症状患者的OHIP-14评分高于无伴随症状者,差异具有统计学意义(P<0.05)。Pearson相关分析显示,口腔健康相关生活质量与疼痛、焦虑、抑郁、睡眠障碍呈正相关(P<0.05)。多元线性回归分析显示,疼痛(B,0.975;95%CI,0.380-1.570)、焦虑(B,0.314;95%CI,0.072-0.557)、睡眠障碍(B,0.359;95%CI,0.075-0.643)为BMS患者口腔健康相关生活质量的影响因素(P<0.05),R2=0.664表明共解释口腔健康相关生活质量66.4%的变异,调整后R2=0.643表明调整后共解释疾病相关知识水平64.3%的变异。结论疼痛、焦虑和睡眠障碍可能是老年BMS患者口腔健康相关生活质量的危险因素。需明确BMS患者的疼痛、心理和睡眠障碍的类型与程度,据此制定多学科综合治疗方案改善患者的口腔健康相关生活质量。

关键词：灼口综合征口腔健康相关生活质量疼痛焦虑抑郁睡眠障碍影响因素

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

月壤参数对月面着陆气囊缓冲性能的影响

引用

国防科技大学学报 2022年第4期44卷 69-80页

作者：周旋周仕明李道奎国防科技大学空天科学学院湖南长沙410073 空天任务智能规划与仿真湖南省重点实验室湖南长沙410073

为研究月壤参数对气囊缓冲性能的影响,根据“嫦娥三号”的着陆工况设计了月面着陆气囊,并基于可压溃泡沫模型建立了考虑月壤特性的气囊缓冲动力学模型。对不同月壤下气囊的缓冲过程进行分析,发现月壤越软有效载荷冲击加速度越小,但气囊... 详细信息

为研究月壤参数对气囊缓冲性能的影响,根据“嫦娥三号”的着陆工况设计了月面着陆气囊,并基于可压溃泡沫模型建立了考虑月壤特性的气囊缓冲动力学模型。对不同月壤下气囊的缓冲过程进行分析,发现月壤越软有效载荷冲击加速度越小,但气囊会陷入月壤中,不利于对外排气,影响其缓冲效果。因此,采用气囊峰值压力、有效载荷最大加速度和最大下落高度3个指标对气囊缓冲性能进行综合评价,定量研究了月壤参数的影响规律。结果表明:月壤密度、剪切模量及屈服参数a_(0)和a_(1)对缓冲性能的影响较大,且对前两个指标为正影响,对后一个指标为负影响。进一步研究发现,这4个月壤参数与3个缓冲性能指标之间均为指数函数关系。

关键词：气囊月面土壤着陆冲击缓冲性能

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

川西柳杉幼林间伐后林下植被和土壤特征变化

引用

西北林学院学报 2024年第1期39卷 44-51页

作者：周璇刘凯利胡佳怡董凯丽赵苏亚龚映匀陈国敏张斌王瑞辉中南林业科技大学林学院湖南长沙410004 广西生态工程职业技术学院广西柳州545004 广西壮族自治区国有七坡林场广西南宁530031 广西壮族自治区南宁良凤江国家森林公园广西南宁530031 黔东南州林业科学研究所贵州凯里556000

为缓解柳杉人工林密度大、林分质量差等问题,对其进行抚育间伐,分析比较林下植被及土壤特征对不同间伐强度的响应,旨在为柳杉人工林的科学经营提供一定的理论基础。以雅安市雨城国有林场羊子岭工区8年生柳杉人工林为研究对象,在初始密度... 详细信息

为缓解柳杉人工林密度大、林分质量差等问题,对其进行抚育间伐,分析比较林下植被及土壤特征对不同间伐强度的响应,旨在为柳杉人工林的科学经营提供一定的理论基础。以雅安市雨城国有林场羊子岭工区8年生柳杉人工林为研究对象,在初始密度为2800株·hm-2的人工林中设置4个强度(对照0%、轻度20%、中度30%、重度40%)开展间伐试验;间伐4 a后,监测并分析其林下植被、土壤特征变化。结果表明,草本层各处理间Shannon指数及Pielou指数差异不显著,轻度间伐多样性指数最低;间伐后灌木层Shannon指数、Pielou指数及物种丰富度显著高于对照,分别是对照处理的7、3、6倍,且灌木层物种丰富度增加量明显高于草本层。间伐可使土壤物理性质得到明显改善,土壤容重随间伐强度增大而显著降低,中度间伐强度相对于对照降低了24.45%,轻度和中度间伐的土壤毛管孔隙度与对照样地差异显著;重度间伐土壤pH及有效磷(P)含量相对于对照显著降低6.79%、25%,土壤有机质、全氮(N)、全磷(P)以及水解N含量随间伐强度的增大而增加,其中轻度间伐处理的土壤有机质含量增加量最高,比对照增加了94.66%。土壤过氧化氢酶和蔗糖酶活性随间伐强度增大而增强,重度间伐和中度间伐活性最高,且与其他处理差异显著。冗余分析结果显示,胸径年增量、草本层植物多样性等均与土壤全N和水解N存在显著相关性。研究表明川西地区柳杉幼林可采取间伐措施改善林分环境。

关键词：柳杉人工林间伐强度林下植被土壤理化性质土壤酶活性冗余分析

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Dissolvable temporary barrier:a novel paradigm for flexible hydrogel patterning in organ-on-a-chip models

引用

Bio-Design and Manufacturing 2024年第2期7卷 153-166页

作者： Ding Wang Qinyu Li Chenyang zhou Zhangjie Li Kangyi Lu Yijun Liu Lian xuan Xiaolin Wang Department of Micro/Nano Electronics School of Electronic Information and Electrical EngineeringShanghai Jiao Tong UniversityShanghai 200240China Department of Ophthalmology LKS Faculty of MedicineThe University of Hong KongHong Kong 999077China Institute of Medical Robotics Shanghai Jiao Tong UniversityShanghai 200240China National Key Laboratory of Advanced Micro and Nano Manufacture Technology Shanghai Jiao Tong UniversityShanghai 200240China National Center for Translational Medicine(Shanghai)SHU Branch Shanghai UniversityShanghai 200444China

A combination of hydrogels and microfluidics allows the construction of biomimetic three-dimensional(3D)tissue models in vitro,which are also known as *** hydrogel patterningwith awell-controlled spatial distribution is typically achieved by embedding sophisticated microstructures to act as a ***,these physical barriers inevitably expose cells/tissues to a less physiologically relevant microenvironment than in vivo ***,we present a novel dissolvable temporary barrier(DTB)strategy that allows robust and flexible hydrogel patterning with great freedom of design and desirable flow stimuli for cellular *** key aspect of this approach is the patterning of a water-soluble rigid barrier as a guiding path for the hydrogel using stencil printing technology,followed by a barrier-free medium perfusion after the dissolution of the *** and multiple tissue compartments with different geometries can be established using either straight or curved DTB *** effectiveness of this strategy is further validated by generating a 3D vascular network through vasculogenesis and angiogenesis using a vascularized microtumor *** a new proof-of-concept in vasculature-on-a-chip,DTB enables seamless contact between the hydrogel and the culture medium in closed microdevices,which is an improved protocol for the fabrication ofmultiorgan ***,we expect it to serve as a promising paradigm for organ-on-a-chip devices for the development of tumor vascularization and drug evaluation in the future preclinical studies.

关键词： Dissolvable temporary barrier Hydrogel patterning Microfluidics Organ-on-a-chip Vascularization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

钻井安全监督周报量化管理初探

引用

化工管理 2024年第6期 110-112页

作者：胡庆勇杜超周旋胡威威杨月明李宝成中海油安全技术服务有限公司天津300457

钻井作为石油勘探开发的关键环节,安全监督管理并及时报告是作业正常进行的重要保障。传统的钻井安全监督管理主要包括人员检查及安全评估,对安全状况依靠人工判断,效率不高,主观性强。通过量化管理,能够更全面、精准地评估钻井作业中... 详细信息

钻井作为石油勘探开发的关键环节,安全监督管理并及时报告是作业正常进行的重要保障。传统的钻井安全监督管理主要包括人员检查及安全评估,对安全状况依靠人工判断,效率不高,主观性强。通过量化管理,能够更全面、精准地评估钻井作业中的风险,采取相应的措施来保障人员安全。探索建立基于量化管理的钻井安全监督周报,分析钻井安全监督周报的内容和指标选择,包括巡检情况统计、问题发现与处理情况、安全培训和教育情况以及安全和环保指标监测等,建立数据分析和指标评估的基础平台,有利于提高钻井安全管理工作的科学性和有效性。

关键词：钻井安全周报量化管理风险评估

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unlocking plant metabolic diversity: A (pan)- genomic view

引用

Plant Communications 2022年第2期3卷 112-120页

作者： xuan zhou Zhenhua Liu Joint Center for Single Cell Biology School of Agriculture and BiologyShanghai Jiao Tong UniversityShanghai 200240China Shanghai Collaborative Innovation Center of Agri-Seeds School of Agriculture and BiologyShanghai Jiao Tong UniversityShanghai 200240China

Plants produce a remarkable diversity of structurally and functionally diverse natural chemicals that serve as adaptive compounds throughout their life ***,unlocking this metabolic diversity is significantly impeded by the size,complexity,and abundant repetitive elements of typical plant *** genome sequencing becomes routine,we anticipate that links between metabolic diversity and genetic variation will be *** addition,an ever-increasing number of plant genomes have revealed that biosynthetic gene clusters are not only a hallmark of microbes and fungi;gene clusters for various classes of compounds have also been found in plants,and many are associated with important agronomic *** present recent examples of plant metabolic diversification that have been discovered through the exploration and exploitation of various genomic and pan-genomic *** also draw attention to the fundamental genomic and pan-genomic basis of plant chemodiversity and discuss challenges and future perspectives for investigating metabolic diversity in the coming pan-genomics era.

关键词： metabolic diversity gene and genome duplication biosynthetic gene clusters genomic structural variations pan-genomics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：