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省域不动产登记数据质量提升技术方法研究与实践

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自然资源信息化 2024年第3期 86-91页

作者：梁庆发辛烜陈彦磊广东省国土资源技术中心广东广州510075

不动产登记数据质量问题是不动产统一登记制度实施以来影响不动产登记公共服务和部门间信息共享应用成效的关键因素,由于客观原因,数据问题难以被全部发现和解决。本文以建立一种持续常态的数据质量提升机制为目的,在分析全省不动产登... 详细信息

不动产登记数据质量问题是不动产统一登记制度实施以来影响不动产登记公共服务和部门间信息共享应用成效的关键因素,由于客观原因,数据问题难以被全部发现和解决。本文以建立一种持续常态的数据质量提升机制为目的,在分析全省不动产登记数据问题的基础上,有针对性地加强增量数据在业务办理过程中的事中数据监管;针对汇交上报成功的全量数据,建立问题数据的协同治理机制,提供问题数据的在线更新办法。同时,应用区块链技术构建不动产登记区块链可信库及其应用,实现以用促治。广东省对上述技术方法进行了组合应用,建立了持续常态化的不动产登记数据质量提升机制,有效提升了不动产登记数据质量。

关键词：不动产登记数据质量数据治理区块链

顾及空间冲突与逻辑一致的不动产登记数据事中监管方法

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自然资源信息化 2024年第3期 126-133页

作者：梁庆发陈彦磊辛烜广东省国土资源技术中心广东广州510075

为提高不动产登记数据的规范性和准确性、避免问题数据逐级积累、提升不动产登记应用服务成效,本文在顾及空间冲突与数据逻辑一致性的条件下,分析设计了不动产登记数据的监管规则和监管技术流程,开发了基于省级不动产登记数据库的统一... 详细信息

为提高不动产登记数据的规范性和准确性、避免问题数据逐级积累、提升不动产登记应用服务成效,本文在顾及空间冲突与数据逻辑一致性的条件下,分析设计了不动产登记数据的监管规则和监管技术流程,开发了基于省级不动产登记数据库的统一监管服务,设计了具体部署架构,并在广东省省域范围进行了具体应用实践。通过持续应用与优化,已形成了省域不动产登记数据的事中监管机制,在不动产登记业务办理过程中通过监管服务加强数据监管从而提升数据质量。应用证明,本文提出的技术方法和应用路径能够有效提升不动产登记数据的完整性、规范性和逻辑性。

关键词：不动产登记信息监管空间冲突数据逻辑一致性

Time in range as a useful marker for evaluating retinal functional changes in diabetic retinopathy patients

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International Journal of Ophthalmology(English edition) 2023年第6期16卷 915-920页

作者： Dan-Dan Zhu xuan Wu xin-xuan Cheng Ning Ding Department of Ophthalmology Nanjing Drum Tower Hospitalthe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210000Jiangsu ProvinceChina Department of Ophthalmology Nanjing Drum Tower Hospital Group Suqian HospitalSuqian 223800Jiangsu ProvinceChina Department of Nutrition and Food Hygiene Nanjing University of Chinese MedicineNanjing 210000Jiangsu ProvinceChina

·AIM:To elucidate the relationship between macular sensitivity and time in range(TIR)obtained from continuous glucose monitoring(CGM)measures in diabetic patients with or without diabetic retinopathy(DR).·METHODS:This was a cross-sectional study including 100 eyes of non-DR patients and 60 eyes of DR *** advanced microperimetry was used to quantitate the retinal mean sensitivity(MS)and fixation stability in central *** of 3.9-10.0 mmol/L was evaluated with *** coefficient analysis and multiple linear regression analysis were used to assess the correlation between TIR and retinal sensitivity.·RESULTS:In a comparison of non-DR patients,significant differences(P0.05).A multivariable linear regression analysis was performed to prove that TIR and SDBG were both independent risk factors for MS reduction in the DR group.·CONCLUSION:TIR is correlated with retinal MS reduction in DR patients,suggesting a useful option for evaluating DR progression.

关键词： diabetic retinopathy time in range microperimetry continuous glucose monitoring

Caution in the use of sedation and endomyocardial biopsy for the management of pediatric acute heart failure caused by endocardial fibroelastosis

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World Journal of Clinical Cases 2023年第22期11卷 5412-5415页

作者： Xiao-xuan xin Yo-Yeng Se School of Hulunbuir Clinical Medicine Inner Mongolia Minzu UniversityHulunbuir 021000Inner Mongolia Autonomous RegionChina Faculty of Medicine The Chinese University of Hong KongHong Kong 999077China Jockey Club College of Veterinary Medicine and Life Sciences City University of Hong KongHong Kong 999077China

Endocardial fibroelastosis(EFE)is commonly considered to be an inflammatory reactive lesion of hyperplasia and deposition of tissue fibers and collagen in the endocardium and/or subendocardium,which is strongly associated with endocardial sclerosis,ventricular remodeling and acute and chronic heart failure,and is one of the important causes for pediatric heart *** diagnosis and treatment are the key factors in determining the prognosis of the *** this paper,we would like to highlight the potential unintended consequences of the use of sedation and biopsy for pediatric acute heart failure caused by EFE and the comprehensive considerations prior to clinical diagnosis.

关键词： Endocardial fibroelastosis Sedation in children Endomyocardial biopsy Comprehensive clinical diagnosis

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发酵果酒中甲醇的研究进展及控制方法

中国酿造 2024年第7期43卷 33-40页

作者：余淑琪丘佳慧杜芷君何美贤辛璇汪薇仲恺农业工程学院轻工食品学院广东广州510225 仲恺农业工程学院广东省岭南特色食品科学与技术重点实验室广东广州510225

甲醇是果酒在发酵过程中产生的有毒副产品,其对果酒的风味和品质有着显著的影响。因此,需要降低甲醇含量并控制其水平。该文对果酒在发酵过程中甲醇形成的机理、影响甲醇形成的因素和控制甲醇含量的方法进行了综述,以期为发酵果酒中甲... 详细信息

甲醇是果酒在发酵过程中产生的有毒副产品,其对果酒的风味和品质有着显著的影响。因此,需要降低甲醇含量并控制其水平。该文对果酒在发酵过程中甲醇形成的机理、影响甲醇形成的因素和控制甲醇含量的方法进行了综述,以期为发酵果酒中甲醇含量的控制方法的进一步研究提供理论依据和参考。

关键词：果酒甲醇形成机理影响因素控制方法

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β连环素表达缺失结直肠癌的临床病理学分析

中华病理学杂志 2024年第3期53卷 288-292页

作者：张杨杨辛萱毕利泉石福云曹瑞雪王艳梅刘晓红解放军第九六〇医院病理科济南250031 山东省东营市河口区人民医院病理科东营257299

目的探讨β连环素缺失结直肠癌的临床病理学表现及分子特征。方法收集2012年1月至2022年11月解放军第九六〇医院诊断为结直肠癌且β连环素丢失表达的病例标本11例,分析其临床、病理和分子改变。结果11例病例中,男性3例,女性8例;年龄43~7... 详细信息

目的探讨β连环素缺失结直肠癌的临床病理学表现及分子特征。方法收集2012年1月至2022年11月解放军第九六〇医院诊断为结直肠癌且β连环素丢失表达的病例标本11例,分析其临床、病理和分子改变。结果11例病例中,男性3例,女性8例;年龄43~74岁,中位年龄59岁;左半结肠6例,右半结肠5例;有淋巴结转移1例,无淋巴结转移10例;高~中分化腺癌10例,黏液腺癌1例;TNM分期T4期8例,T1期2例,Tis期1例。肿瘤细胞免疫组织化学染色均不表达β连环素。Sanger测序显示CTNNB1基因第3号外显子存在片段缺失突变,导致蛋白缺失表达。结论β连环素缺失结直肠癌是一类少见的亚群,可能与CTNNB1基因第3号外显子突变相关。

关键词：结直肠肿瘤 β连环素 DNA突变分析免疫组织化学

Accelerated heterogenous ring-opening polymerization towards well-defined helical poly(N-allyl alanine)with clickable side chains

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Science China Chemistry 2024年第6期67卷 2056-2062页

作者： Anyao Ma xin Wang Sunting xuan Zhengbiao Zhang College of Chemistry Chemical Engineering and Materials ScienceSoochow UniversitySuzhou215123China State Key Laboratory of Radiation Medicine and Protection Soochow UniversitySuzhou215123China

Well-defined poly(N-allyl alanine)has been synthesized by heterogenous ring-opening polymerization(HROP)of less reactive N-allyl-alanine N-carboxyanhydride,using acetic acid as the catalyst and benzylamine as the initiator,in non-polar ***,the polymerization exhibited typical features of living polymerization though both monomer(liquid)and polymer(solid)have minimal solubility in *** obtained polymer showed a stable helix structure independent of the temperatures screened,as evidenced by circular dichroism ***,the preliminary study demonstrated that the side chains can be post-functionalized through thiol-ene click chemistry with quantitative ***,this work provides guidance for the development of accelerated HROP of other liquid monomers bearing low ***,the helical and functionalizable poly(N-allyl alanine)could be a useful“clickable platform”for the design of variable biomaterials via efficient click chemistry.

关键词： heterogenous ring-opening polymerization controlled polymerization stable helix clickable N-substituted polypeptide di-substituted polypeptoid

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基于OBE理念的“生药学”课程思政实践探索

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教育教学论坛 2024年第11期 113-116页

作者：王鑫璇赵彦巧赵辉阮海华天津商业大学生物技术与食品科学学院天津300134

在“生药学”的教学过程中,基于OBE理念,以相关政策法规为学科发展依据,建立价值引导、知识传授、能力培养相结合的“三位一体”培养目标,以学生为本,抓住教学目标特点,多形式、多角度融入课程思政内容。思政内容与药学专业有机融合,基... 详细信息

在“生药学”的教学过程中,基于OBE理念,以相关政策法规为学科发展依据,建立价值引导、知识传授、能力培养相结合的“三位一体”培养目标,以学生为本,抓住教学目标特点,多形式、多角度融入课程思政内容。思政内容与药学专业有机融合,基于行业、企业发展需要和职业岗位实际工作要求,通过考核结果及学生反馈持续改进。在掌握专业知识、发展素质能力的同时,培养学生树立正确的人生观、价值观,严守职业操守,传承中华智慧、树立文化自信,实现学生教育培养的个性化、人性化、独特化。

关键词： OBE理念生药学课程思政 “三位一体” 实践性教学

Climate change,ambient air pollution,and students'mental health

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World Journal of Psychiatry 2024年第2期14卷 204-209页

作者： Jing-xuan Wang xin-Qiao Liu School of Education Tianjin UniversityTianjin 300350China

The impact of global climate change and air pollution on mental health has become a crucial public health *** public awareness of health,advancements in medical diagnosis and treatment,the way media outlets report environmental changes and the variation in social resources affect psychological responses and adaptation methods to climate change and air *** the context of climate change,extreme weather events seriously disrupt people's living environments,and unstable educational environments lead to an increase in mental health issues for *** pollution affects students'mental health by increasing the incidence of diseases while decreasing contact with nature,leading to problems such as anxiety,depression,and decreased cognitive *** call for joint efforts to reduce pollutant emissions at the source,improve energy structures,strengthen environmental monitoring and governance,increase attention to the mental health issues of students,and help student groups build resilience;by establishing public policies,enhancing social support and adjusting lifestyles and habits,we can help students cope with the constantly changing environment and maintain a good level of mental *** these comprehensive measures,we can more effectively address the challenges of global climate change and air pollution and promote the achievement of the United Nations Sustainable Development Goals.

关键词： Climate change Ambient air pollution Mental health Energy structure Public policy Sustainable development