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Experimental Study of Mooring Type Effect on the Hydrodynamic Characteristics of VLFS

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China Ocean Engineering 2022年第1期36卷 155-166页

作者： FENG Ming-wei SUN Zhao-chen LIANG Shu-xiu LI Zhi lv xuan JIA Song-lin HUXin-yue State Key Laboratory of Coastal and Offshore Engineering Dalian University of TechnologyDalian 116024China

Mooring system is a significant part of very large offshore floating structures(VLFS).In this paper,a single module pontoon type VLFS model considering four mooring types is studied through physical model tests to determine the effects of mooring conditions on the hydroelastic response,mooring force,incident coefficient,reflection coefficient and energy dissipation *** mooring cables are symmetrically arranged on both sides of the *** floating body model satisfies the similarity of stiffness and gravity,while the cable satisfies the similarity of elasticity and *** results show that the effect of mooring type on mooring force is greater than that on hydroelastic *** the initial tension of the mooring cable will reduce the amplitude of the leeward of the VLFS *** mooring angle of the mooring cable will affect the maximum mooring force and the initial tension of the mooring line will affect the wave period in which the maximum mooring force *** transmission coefficient and wave energy dissipation coefficient will change regularly with different mooring *** results may provide a reference to facilitate the mooring design of VLFS.

关键词： VLFS hydroelastic response mooring system 3D experimental test mooring force wave reflection coefficient wave transmission coefficient wave dissipation coefficient

From Phenotypes to Molecules: Revolutionizing Gut Microbiota Identification Methods

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中国生物化学与分子生物学报 2024年第8期40卷 1065-1077页

作者： WANG xuan lv Chang-Long ZHAI Jing-Bo Medical College Inner Mongolia Minzu UniversityTongliao 028000Inner MongoliaChina Research Centre of Chemical Biology Yanbian UniversityYanji 133002JilinChina Key Laboratory of Zoonose Prevention and Control at Universities of Inner Mongolia Autonomous Region Tongliao 028000Inner MongoliaChina Institute of Immunology China Medical UniversityShenyang 110000LiaoningChina Brucellosis Prevention and Treatment Engineering Research Center of Inner Mongolia Autonomous Region Tongliao 028000Inner MongoliaChina

The gut microbiota is a complex ecosystem composed of many bacteria and their *** plays an irreplaceable role in human digestion,nutrient absorption,energy supply,fat metabolism,immune regulation,and many other *** the structure and function of the gut microbiota,as well as their key genes and metabolites,will enable the early diagnosis and auxiliary diagnosis of diseases,new treatment methods,better effects of drug treatments,and better guidance in the use of *** identification of gut microbiota plays an important role in clinical diagnosis and treatment,as well as in drug research and ***,it is necessary to conduct a comprehensive review of this rapidly evolving *** identification methods cannot comprehensively capture the diversity of gut ***,with the rapid development of molecular biology,the classification and identification methods for gut microbiota have evolved from the initial phenotypic and chemical identification to identification at the molecular *** review integrates the main methods of gut microbiota identification and evaluates their *** pay special attention to the research progress on molecular biological methods and focus on the application of high-throughput sequencing technology in the identification of gut *** revolutionary method for intestinal flora identification heralds a new chapter in our understanding of the microbial world.

关键词： gut microbiota 16S rRNA real-time fluorescent qPCR high-throughput sequencing mass spectrum

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Role of in-situ formed free carbon on electromagnetic absorption properties of polymer-derived SiC ceramics

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Journal of Advanced Ceramics 2020年第5期9卷 617-628页

作者： Zhaoju YU xuan lv Kangwei MAO Yujing YANG Anhua LIU College of Materials Key Laboratory of High Performance Ceramic Fibers(Xiamen University)Ministry of EducationXiamen 361005China College of Materials Fujian Key Laboratory of Advanced Materials(Xiamen University)Xiamen 361005China Shenzhen Research Institute of Xiamen University Shenzhen 518000China

In order to enhance dielectric properties of polymer-derived SiC ceramics,a novel single-source-precursor was synthesized by the reaction of an allylhydrido polycarbosilane(AHPCS)and divinyl benzene(DVB)to form carbon-rich *** expected,the free carbon contents of resultant SiC ceramics annealed at 1600℃are significantly enhanced from 6.62 wt%to 44.67 wt%.After annealing at 900-1600℃,the obtained carbon-rich SiC ceramics undergo phase separation from amorphous to crystalline feature where superfine SiC nanocrystals and turbostratic carbon networks are dispersed in an amorphous SiC(O)*** dielectric properties and electromagnetic(EM)absorption performance of as-synthesized carbon-rich SiC ceramics are significantly improved by increasing the structural order and content of free *** the 1600℃ ceramics mixed with paraffin wax,the minimum reflection coefficient(RCmin)reaches-56.8 dB at 15.2 GHz with the thickness of 1.51 mm and a relatively broad effective bandwidth(the bandwidth of RC values lower than-10 dB)of 4.43 GHz,indicating the excellent EM absorption *** carbon-rich SiC ceramics have to be considered as harsh environmental EM absorbers with excellent chemical stability,high temperature,and oxidation and corrosion resistance.

关键词： polymer-derived ceramics(PDCs) microstructural evolution dielectric properties electromagnetic properties

^(18)F-prostate specific membrane antigen positron emission tomography/computerized tomography for lymph node staging in medium/high risk prostate cancer:A systematic review and meta-analysis

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Chinese Medical Journal 2024年第8期137卷 949-958页

作者： Zhengtong lv Liuqi Song Miao Wang Huimin Hou Haodong Li xuan Wang Jianye Wang Jianlong Wang Ming Liu Department of Urology Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing 100730China Graduate School of Peking Union Medical College and Chinese Academy of Medical Sciences Beijing 100730China Peking University Fifth School of Clinical Medicine Beijing 100730China Peking University China-Japan Friendship School of Clinical Medicine Beijing 100029China

Background:Lymph node staging of prostate cancer(PCa)is important for planning and monitoring of treatment.^(18)F-prostate specific membrane antigen positron emission tomography/computerized tomography(^(18)F-PSMA PET/CT)has several advantages over^(68)Ga-PSMA PET/CT,but its diagnostic value requires further *** meta-analysis focused on establishing the diagnostic utility of^(18)F-PSMA PET/CT for lymph node staging in medium/high-risk ***:We searched the EMBASE,PubMed,Cochrane library,and Web of Science databases from inception to October 1,*** cancer,^(18)F,lymph node,PSMA,and PET/CT were used as search terms and the language was limited to *** additionally performed a manual search using the reference lists of key *** and study characteristics were extracted and the QUADAS-2 tool was employed to evaluate the quality of included ***,specificity,the positive and negative likelihood ratio(PLR and NLR),diagnostic odds ratio(DOR),area under the curve(AUC),and 95%confidence interval(CI)were used to evaluate the diagnostic value of^(18)F-PSMA PET/*** 17 software was employed for calculation and statistical ***:A total of eight diagnostic tests including 734 individual samples and 6346 lymph nodes were included in this *** the patient level,the results of each consolidated summary were as follows:sensitivity of 0.57(95%CI 0.39-0.73),specificity of 0.95(95%CI 0.92-0.97),PLR of 11.2(95%CI 6.6-19.0),NLR of 0.46(95%CI 0.31-0.68),DOR of 25(95%CI 11-54),and AUC of 0.94(95%CI 0.92-0.96).At the lesion level,the results of each consolidated summary were as follows:sensitivity of 0.40(95%CI 0.21-0.62),specificity of 0.99(95%CI 0.95-1.00),PLR of 40.0(95%CI 9.1-176.3),NLR of 0.61(95%CI 0.42-0.87),DOR of 66(95%CI 14-311),and AUC of 0.86(95%CI 0.83-0.89).Conclusions:^(18)F-PSMA PET/CT showed moderate sensitivity but high specificity in lymph node staging of medium/high-risk *** diag

关键词： ^(18)F-PSMA PET/CT Diagnostic test Lymph node Meta-analysis Prostate cancer

ZrC-ZrB_2-SiC ceramic nanocomposites derived from a novel single-source precursor with high ceramic yield

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Journal of Advanced Ceramics 2019年第1期8卷 112-120页

作者： Zhaoju YU xuan lv Shuyi LAI Le YANG Wenjing LEI Xingang LUAN Ralf RIEDEL College of Materials Key Laboratory of High Performance Ceramic Fibers (Xiamen University) Ministry of Education College of Materials Fujian Key Laboratory of Advanced Materials (Xiamen University) College of Materials Science and Engineering Huaqiao University Science and Technology on Thermostructural Composite Materials Laboratory Northwestern Polytechnical University Technische Universit?t Darmstadt Institut für Materialwissenschaft

For the first time, ZrC-ZrB_2-SiC ceramic nanocomposites were successfully prepared by a single-source-precursor route, with allylhydridopolycarbosilane(AHPCS),triethylamine borane(TEAB),and bis(cyclopentadienyl) zirconium dichloride(Cp_2 ZrCl_2) as starting materials. The polymer-to-ceramic transformation and thermal behavior of obtained single-source precursor were characterized by means of Fourier transform infrared spectroscopy(FT-IR) and thermal gravimetric analysis(TGA). The results show that the precursor possesses a high ceramic yield about 85% at 1000 ℃.The phase composition and microstructure of formed ZrC-ZrB_2-SiC ceramics were investigated by means of X-ray diffraction(XRD) and high resolution transmission electron microscopy(HRTEM).Meanwhile, the weight loss and chemical composition of the resultant ZrC-ZrB_2-SiC nanocomposites were investigated after annealing at high temperature up to 1800 ℃. High temperature behavior with respect to decomposition as well as crystallization shows a promising high temperature stability of the formed ZrC-ZrB_2-SiC nanocomposites.

关键词： polymer derived ceramics single-source precursor ceramic nanocomposite

The Earth Summit Mission-2022:Successful ozone soundings contribute to source identification in the north *** region

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Journal of Environmental Sciences 2024年第2期136卷 412-421页

作者： Jinqiang Zhang Chunxiang Ye Yuejian xuan Zhixuan Bai Weili Lin Dan Li Lingkun Ran Baofeng Jiao YaomingMa Weiqiang Ma Nan Yao Yunshu Zeng Daren lv Tong Zhu Key Laboratory of Middle Atmosphere and Global Environment Observation Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China College of Environmental Sciences and Engineering Center for Environment and HealthPeking UniversityBeijing 100871China Key Laboratory of Ecology and Environment in Minority Areas(Minzu University of China) National Ethnic Affairs CommissionBeijing 100081China Key Laboratory of Cloud-Precipitation Physics and Severe Storms Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Land-Atmosphere Interaction and Its Climatic Effects Group State Key Laboratory of Tibetan Plateau Earth SystemResources and Environment(TPESRE)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China College of Atmospheric Science Lanzhou UniversityLanzhou 730000China National Observation and Research Station for Qomolongma Special Atmospheric Processes and Environmental Changes Dingri 858200China Kathmandu Center of Research and Education Chinese Academy of SciencesBeijing 100101China China-Pakistan Joint Research Center on Earth Sciences Chinese Academy of SciencesIslamabad 45320Pakistan Electronic Engineering College Chengdu University of Information TechnologyChengdu 610225China

As part of“The Earth Summit Mission-2022”during the second Tibetan Plateau Scientific Expedition and Research(STEP)in April and May 2022,we conducted the ozone sounding experiment(an ozonesonde mated to a radiosonde)at *** Base Camp(MQBC;86.85°E,28.14°N;5200 m),a location at an extremely high altitude.A total of ten sounding profiles were obtained between April 30 and May 06,2022,of which seven profiles were above35 km in altitude,with a maximum detection altitude up to 39.0 *** study presents the temporal variation and vertical distributions of atmospheric temperature,humidity,and ozone during the MQBC *** averaged ozone concentration was high(68.3 ppbv)at the surface and then increased smoothly until peaking(~110 ppbv)in the middle troposphere(approximately 10 km),and afterward,the ozone concentration increased rapidly from the upper troposphere to a maximum of~10 ppmv at~30 *** enhanced ozone concentration in the middle troposphere was associated with the blocking high pressure,and transport from the southern flank of the Himalayas occurred during the campaign *** average total ozone column was 291.9±21.4 DU for the seven profiles exceeding 35km in *** ozonesonde measurements were also compared with the vertical ozone profiles retrieved from the space-borne ozone products from the Microwave Limb Sounder(MLS)onboard the Aura satellite and the Atmospheric Infrared Sounder(AIRS)onboard the Aqua satellite.

关键词： Ozone soundings Mt.Qomolangma Vertical ozone structure Ozone source Satellite data

Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases

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Chronic Diseases and Translational Medicine 2017年第4期3卷 207-212页

作者： Jun-xuan lv Qi Kong Xin Ma Department of Neurology Xuanwu Hospital of Capital Medical University National Clinical Research Center for Geriatric Disorders Clinical Center for Cardio-cerebrovascular Disease Capital Medical University Beijing 100053 China

Atherosclerosis (AS) is a systemic chronic disease affecting both the coronary and cerebral arteries. Inflammation plays a key role in the initiation and progression of AS, and numerous inflammatory factors have been proposed as potential biomarkers. This article reviews recent research in studies on major circulating inflammatory biomarkers to identify surrogates that may reflect processes associated with AS development and the risk of AS-related vascular events, such as Von Willebrand factor, lectin-like oxidized low-density-lipoprotein receptor-1, soluble urokinase plasminogen activator receptor, regulated upon activation, normal T-cell expressed and secreted, and microparticles, which may provide new perspectives for clinical AS evaluation and risk stratification.

关键词： Atherosclerosis Inflammatory biomarkers Plaques Risk factors

A cell transcriptomic profile p ovides insights into adipocytes of porcine mammary gland across development

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Journal of Animal Science and Biotechnology 2024年第1期15卷 182-200页

作者： Yongliang Fan Long Jin Zhiping He Tiantian Wei Tingting Luo Jiaman Zhang Can Liu Changjiu Dai Chao A Yan Liang xuan Tao Xuebin lv Yiren Gu Mingzhou Li State Key Laboratory of Swine and Poultry Breeding Industry College of Animal Science and TechnologySichuan Agricultural UniversityChengdu 611130China Key Laboratory of Qinghai‑Tibetan Plateau Animal Genetic Resource Reservation and Utilization Southwest Minzu UniversityChengdu 610041China Animal Breeding and Genetics Key Laboratory of Sichuan Province Sichuan Animal Science AcademyChengdu 610000China

Background Studying the composition and developmental mechanisms in mammary gland is crucial for healthy growth of newborns. The mammary gland is inherently heterogeneous, and its physiological function dependents on the gene expression of multiple cell types. Most studies focused on epithelial cells, disregarding the role of neighboring *** Here, we constructed the largest transcriptomic dataset of porcine mammary gland cells thus far. The dataset captured 126,829 high-quality nuclei from physiological mammary glands across five developmental stages(d 90 of gestation, G90;d 0 after lactation, L0;d 20 after lactation, L20;2 d post natural involution, PI2;7 d post natural involution, PI7). Seven cell types were identified, including epithelial cells, adipocytes, endothelial cells, fibroblasts cells, immune cells, myoepithelial cells and precursor cells. Our data indicate that mammary glands at different developmental stages have distinct phenotypic and transcriptional signatures. During late gestation(G90), the differentiation and proliferation of adipocytes were inhibited. Meanwhile, partly epithelial cells were completely differentiated. Pseudo-time analysis showed that epithelial cells undergo three stages to achieve lactation, including cellular differentiation, hormone sensing, and metabolic activation. During lactation(L0 and L20), adipocytes area accounts for less than 0.5% of mammary glands. To maintain their own survival, the adipocyte exhibited a poorly differentiated state and a proliferative capacity. Epithelial cells initiate lactation upon hormonal stimulation. After fulfilling lactation mission, their undergo physiological death under high intensity lactation. Interestingly, the physiological dead cells seem to be actively cleared by immune cells via CCL21-ACKR4 pathway. This biological process may be an important mechanism for maintaining homeostasis of the mammary gland. During natural involution(PI2 and PI7), epithelial cell populatio

关键词： Adipocytes Cell–cell interaction Development Mammary gland snRNA-seq

Advancing Energy Systems with In-Situ and Operando Surface-Enhanced Raman Scattering Spectroscopy

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CCS Chemistry 2024年第6期6卷 1403-1421页

作者： Haoming Bao Shi xuan Leong Jaslyn Ru Ting Chen Zhenhai Shi Suli Chen Yan lv Tianxi Liu In Yee Phang Xing Yi Ling Key Laboratory of Synthetic and Biological Colloids Ministry of EducationInternational Joint Research Laboratory for Nano Energy CompositesSchool of Chemical and Material EngineeringJiangnan UniversityWuxi 214122 School of Chemistry Chemical Engineering and BiotechnologyNanyang Technological UniversitySingapore 637371

Surface-enhanced Raman scattering spectroscopy(SERS)has emerged as a powerful analytical technique to enable nanoscale investigations of energy *** mini-review focuses on the applications of in-situ and operando SERS in energy-related research,highlighting its unique capabilities and significant contributions to understanding energy storage and conversion *** first introduce the fundamental principles of SERS,key SERS-derived techniques,and commonly employed ***,we delve into the diverse applications of in-situ and operando SERS across various energy systems,encompassing photocatalytic and electrocatalytic systems,fuel cells,solar cells,and ***,we conclude with our perspective on the current challenges and prospects in this *** hope thismini-review serves as an essential overview to guide the design and implementation of in-situ and operando SERS studies of energy systems.

关键词： surface-enhanced Raman scattering spectroscopy in-situ operando energy systems photocatalysis electrocatalysis fuel cells solar cells batteries