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Topological Aspects of Triplet Superconductors

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Communications in Theoretical Physics 2007年第5期47卷 944-948页

作者： REN Ji-Rong xu Dong-hui zhang Xin-hui LI Ran Institute of Theoretical Physics Lanzhou University Lanzhou 730000 China

In this paper, using the Φ-mapping theory, it is shown that two kinds of topological defects, i.e., the vortex lines and the monopoles exist in the helical configuration of magnetic field in triplet superconductors. And the inner topological structure of these defects is studied. Because the knot solitons in the triplet superconductors are characterized by the Hopf invariant, we also establish a relationship between the Hopf invariant and the linking number of knots family, and reveal the inner topological structure of the Hopf invariant.

关键词： triplet superconductor topological defects Hopf invariant

Topological Aspects of Superconductors at Dual Point

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Communications in Theoretical Physics 2008年第6期49卷 1627-1630页

作者： REN Ji-Rong xu Dong-hui zhang Xin-hui DUAN Yi-Shi Institute of Theoretical Physics Lanzhou University Lanzhou 730000 China

We study the properties of the Ginzburg-Landau model at the dual point for the superconductors. By making use of the U（1） gauge potential decomposition and the φ-mapping theory, we investigate the topological inner structure of the Bogomol＇nyi equations and deduce a modified decoupled Bogomol＇nyi equation with a nontrivial topological term, which is ignored in conventional model. We find that the nontrivial topological term is closely related to the N-vortex, which arises from the zero points of the complex scalar field, Furthermore, we establish a relationship between Ginzburg Landau free energy and the winding number.

关键词： dual point Bogomol'nyi equations vortex

Experimental study on mechanical properties of methane-hydrate-bearing sediments

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Acta Mechanica Sinica 2012年第5期28卷 1356-1366页

作者： xu-hui zhang Xiao-Bing Lu Li-Min zhang Shu-Yun Wang Qing-Ping Li Laboratory for Hydrodynamics and Ocean Enginnering Institute of MechanicsChinese Academy of Sciences Department of Civil and Environmental Engineering Hong KongUniversity of Science and Technology Research Centre China Ocean Oil Co.

Mechanical properties of methane hydrate- bearing-sediments （MHBS） are basic parameters for safety analysis of hydrate exploration and exploitation. Young＇s modulus, cohesion, and internal friction angle of hydrate- bearing sediments synthesized in laboratory, are investigated using tri-axial tests. Stress-strain curves and strength parameters are obtained and discussed for different compositions and different hydrate saturation, followed by empirical expressions related to the cohesion, internal friction angle, and modulus of MHBS. Almost all tested MHBS samples exhibit plastic failure. With the increase of total saturation of ice and methane hydrate （MH）, the specimens＇ internal friction angle decreases while the cohesion increases.

关键词： Gas hydrate sediment. Tri-axial test. Cohesion Internal friction angle Elastic modulus

Synthesis and Antitumor Activity of 7-Substituted Derivatives of Homocamptothecin

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Chinese Chemical Letters 2006年第6期17卷 720-722页

作者： Zhen Yuan MIAO Wan Nian zhang Jian Zhong YAO Chun Quan SHENG Yun Long SONG hui xu Min zhang Jing zhang School of Pharmacy Second Military Medical University Shanghai 200433

Thirteen homocamptothecin derivatives were synthesized and in vitro antitumor activities were evaluated by the standard MTT method. The results showed that some of the homocamptothecin derivatives had higher antitumor... 详细信息

关键词： Antitumor activity homocamptothecin synthesis.

Design of Tough, yet Strong, Heat-resistant PLA/PBAT Blends with Reconfigurable Shape Memory Behavior by Engineering Exchangeable Covalent Crosslinks

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Chinese Journal of Polymer Science 2023年第12期41卷 1868-1878,I0007页

作者： Xiao-Wen Zhou Jing Huang xu-hui zhang Ting Li Yang Wang Shi-Bo Wang Bi-Hua Xia Wei-Fu Dong The Key Laboratory of Synthetic and Biological Colloids Ministry of EducationSchool of Chemical and Material EngineeringJiangnan UniversityWuxi 214122China

Polylactide(PLA)has often been blended with biodegradable poly(butylene adipate-co-terephthalate)(PBAT)to improve its ***,the strength and heat resistance of PLA are always ***,exchangeable hydroxyl-ester crosslinks are constructed in PLA/PBAT blends by successively introducing a tertiary amine-containing polyol,bis-(2-hydroxyethyl)amino-tris(hydroxymethyl)methane(BTM)and 4,4’-diphenylmethane diisocyanate(MDI)via reactive *** can react with both PLA and PBAT by transesterification,generating PLA or PBAT chains with terminal or pendant hydroxyl groups,which can then react with MDI to form *** internal catalysis of tertiary amine moiety in BTM,transesterification between the residual hydroxyl groups and ester bonds can occur at high temperatures,endowing the PLA/PBAT network with vitrimeric *** to the transesterification and chain extension reactions with MDI between PLA and PBAT,the interfacial adhesion is greatly *** a result of the excellent interfacial adhesion and the network structure,the prepared PLA/PBAT blends show greatly enhanced heat resistance and toughness(more than 40 times that of PLA)while maintaining high stiffness comparable to ***,the prepared PLA/PBAT blends exhibit promising reconfigurable shape memory *** present work provides a new and facile way to achieve high-performance and functional biodegradable polymeric materials.

关键词： Polylactide Dynamic covalent bonds Strengthening and toughening Heat resistance Shape memory

Survival and prognostic factors of non-small cell lung cancer patients with postoperative locoregional recurrence treated with radical radiotherapy

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Chinese Journal of Cancer 2017年第11期36卷 657-664页

作者： Li Ma Bo Qiu Jun zhang Qi-Wen Li Bin Wang xu-hui zhang Meng-Yun Qiang Zhao-Lin Chen Su-Ping Guo hui Liu Department of Radiation Oncology Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine 651 Dongfeng Road EastGuangzhou Guangdong 510060 P. R. China

Background: Locoregional recurrence remains the challenge for long-term survival of non-small cell lung cancer(NSCLC) patients after radical surgery, and curative-intent radiotherapy could be a treatment choice. This study aimed to assess the survival and prognostic factors of patients with postoperative locoregionally recurrent NSCLC treated with radical ***: We reviewed medical records of 74 NSCLC patients with postoperative locoregional recurrence who received radical radiotherapy between April 2012 and February 2016 at Sun Yat-sen University Cancer Center(Guangzhou, China). The efficacy and safety of radical radiotherapy were analyzed. The probability of survival was estimated using the Kaplan-Meier method and compared using the log-rank test. The Cox proportional hazards model was used to identify prognostic ***: Grade 3/4 adverse events included neutropenia(8 cases, 10.8%), esophagitis(7 cases, 9.5%), pneumonitis(1 case, 1.4%), and vomiting(1 case, 1.4%).The 2-year overall survival, progression-free survival, local recurrencefree survival(LRFS), and distant metastasis-free survival(DMFS) rates of all patients were 84.2,42.5,70.0, and 50.9%,respectively. Univariate and multivariate analyses showed that a higher biological effective dose(BED) of radiation was associated with longer LRFS [hazard ratios(HR)=0.317,95% confidence interval(CI) = 0.112-0.899, P = 0.016] and that wild-type epidermal growth factor receptor(EGFR) was associated with longer DMFS compared with EGFR mutation(HR = 0.383,95% CI=0.171-0.855, P = 0.019).Conclusions: Radical radiotherapy is effective and well-tolerated in NSCLC patients with postoperative locoregional recurrence. High BED is a predictor for long LRFS, and the presence of wild-type EGFR is a predictor for long DMFS.

关键词： Non-small cell lung cancer Locoregional recurrence Radical radiotherapy Biological effective dose Epidermal growth factor receptor

Electroacupuncture pretreatment exhibits antidepressive effects by regulating hippocampal proteomics in rats with chronic restraint stress

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Neural Regeneration Research 2015年第8期10卷 1298-1304页

作者： Zhuo Guo Ya Tu Tian-wei Guo Yun-chu Wu xue-qin Yang Lan Sun Xin-jing Yang Wen-yue zhang Yu Wang xu-hui zhang Beijing University of Chinese Medicine Shijiazhuang Hospital of Traditional Chinese Medicine Beijing Rehabilitation Hospital of Capital Medical University

The clinical effect of electroacupuncture on depression is widely recognized. However, the signal transduction pathways and target proteins involved remain unclear. In the present study, rat models of chronic restraint stress were used to explore the mechanism by which electroacupuncture alleviates depression. Rats were randomly divided into control, model, and electroacupuncture groups. Chronic restraint stress was induced in the model and electroacupuncture groups by restraining rats for 28 days. In the electroacupuncture group, electroacupuncture pretreatment at Baihui（GV20） and Yintang（GV29） acupoints was performed daily（1 m A, 2 Hz, discontinuous wave, 20 minutes） prior to restraint for 28 days. Open field tests and body weight measurements were carried out to evaluate the depressive symptoms at specific time points. On day 28, the crossing number, rearing number, and body weights of the model group were significantly lower than those in the control group. Behavior test results indicated that rat models of depressive-like symptoms were successfully established by chronic restraint stress combined with solitary raising. On day 28, an isobaric tag for a relative and absolute quantitation-based quantitative proteomic approach was performed to identify differentially expressed proteins in hippocampal samples obtained from the model and electroacupuncture groups. The potential function of these differential proteins was predicted through the use of the Cluster of Orthologous Groups of proteins（COG） database. Twenty-seven differential proteins（uncharacteristic proteins expected） were selected from the model and electroacupuncture groups. In addition to unknown protein functions, COG are mainly concentrated in general prediction function, mechanism of signal transduction, amino acid transport and metabolism groups. This suggests that electroacupuncture improved depressive-like symptoms by regulating differential proteins, and most of these related proteins exist in ne

关键词： nerve regeneration traditional Chinese medicine electroacupuncture depression chronic restraint stress i TRAQ differential protein proteomics multi-target effect neural regeneration

Stability analysis of seabed strata and casing structure during the natural gas hydrates exploitation by depressurization in horizontal wells in South China Sea

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China Geology 2022年第2期5卷 300-309页

作者： Peng-fei Xie Lin Yang Qian-yong Liang xu-hui zhang Liang-hua zhang Bin zhang Xiao-bing Lu hui-ce He xue-min Wu Yi-fei Dong Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou 511458China Guangzhou Marine Geological Survey China Geological SurveyMinistry of Natural ResourcesGuangzhou 510760China Institute of Mechanics Chinese Academy of SciencesBeijing 100190China China University of Geosciences(Beijing) Beijing 100084China University of Chinese Academy of Sciences Beijing 100049China National Engineering Research Center of Gas Hydrate Exploration and Development Guangzhou 511400China

Natural gas hydrates(NGHs)are a new type of clean energy with great development ***,it is urgent to achieve safe and economical NGHs development and *** study established a physical model of the study area using the FLAC^(3D) software based on the key parameters of the NGHs production test area in the South China Sea,including the depressurization method,and mechanical parameters of strata,NGHs occurrence characteristics,and the technological characteristics of horizontal ***,this study explored the law of influences of the NGHs dissociation range on the stability of the overburden strata and the casing structure of a horizontal *** results are as *** the dissociation of NGHs,the overburden strata of the NGHs dissociation zone subsided and formed funnelshaped zones and then gradually ***,the upper interface of the NGHs dissociation zone showed significant redistribution and discontinuity of ***,distinct stress concentration and corresponding large deformation occurred in the build-up section of the horizontal well,which was thus prone to suffering shear ***,apparent end effects occurred at the end of the horizontal well section and might cause the deformation and failure of the casing ***,it is necessary to take measures in the build-up section and at the end of the horizontal section of the horizontal well to prevent damage and ensure the wellbore safety in the long-term NGHs exploitation.

关键词： Natural gas hydrates(NGHs) Exploitation by depressurization Horizontal well Stratum subsidence Shear failure NGHs exploration trial engineering Oil and gas exploration engineering Shenhu Area South China Sea

Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation for Thymoma-associated Severe Aplastic Anemia: a Case Report

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Chinese Medical Sciences Journal 2013年第3期28卷 189-191页

作者： Cong Lu Guang-sheng He Song Jin xu-hui zhang Xiao-hui Hu De-pei Wu Ai-ning Sun Chang-geng Ruan Key Laboratory of Thrombosis and Hemostasis of National Health and Family Planning Commission of the People's Republic of China Jiangsu Insititute of HematologyDepartment of Hematology the First Affiliated Hospital of Soochow University

THYMOMA, a relatively rare epithelial neoplasm with unique clinical and pathologic features, is the most usual diagnosis for a mass located in the mediastinum. It is often associated withautoimmune disorders. The myastnema gravls ano pure red cell aplasia are the most common disorders, with the incidences of 40% and 5%, respectively, while the incidence of aplastic anemia is only about 0-1.4%. 1 Thymectomy is hard to perform on patients with severe aplastic anemia（SAA） due to severe pancytopenia.

关键词： haploidentical allogeneic hematopoietic stem cell transplantation malignant thymoma severe aplastic anemia