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Statistical characteristics and effects of polarization mode dispersion in dispersion managed soliton systems

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Optoelectronics Letters 2006年第3期2卷 199-202,216页

作者： xu ming ji jian-hua Advanced Technology Research Center of Information Engineering College Shenzhen University Shenzhen 518060 China

Firstly,the JME（Jones matrix eigen） method is used to simulate the statistical characteristics of first- and second-order PMD in dispersion management system. Then,with help of the CNLSE （coupled nonlinear Schrodinger equations） ,the effects of PMD on DMS （dispersion managed soliton） transmission is studied with a variational method. The simplified relationships of the statistical parameters of second-order and first-order of PMD in dispersion management system have been gotten,from which the detailed information of second-order can be obtained, if the condition of DGD is given. The results have shown that the first and second-order PMD （polarization mode dispersion） vectors influence the evolution of energy and Mean square of time displacement of DMS in high-speed bit rates systems. When DPMD^1st〉0.3 ps/km^1/2 ,we must consider some means of control（for example the filter） to restrain the PMD.

关键词：光纤通信孤立子系统偏振模式色散

Two New Schiff Bases Based on 5-Chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde: Syntheses, Crystal Structures and Properties

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Chinese Journal of Structural Chemistry 2019年第3期38卷 408-415页

作者： SUN Feng-Mei HAN Qiong jiANG Zheng-jing ZHAO Pan-Xiang WANG jia RUI jia-Yi xu ji-ming School of Chemistry and Chemical Engineering Huaiyin Normal University

Two new Schiff bases based on 5-chloro-3-methyl-1-phenyl-1 H-pyrazole-4-carbaldehyde, namely, N-((5-chloro-3-methyl-1-phenyl-1 H-pyrazol-4-yl)methylene)-4-morpholinoaniline(Ⅲa) and N-((5-chloro-3-methyl-1-phenyl-1 H-pyrazol-4-yl)methylene)-3-fluoro-4-morpholinoaniline(Ⅲb), were synthesized and characterized by IR, LC-MS, 1 H NMR and 13 C NMR spectroscopy. Meanwhile, the three-dimensional configurations of the two title compounds were further characterized by single-crystal X-ray diffraction analyses. Both the compounds are thermodynamically stable trans-isomers. Moreover, the fluorescence properties and antioxidant activities against DPPH of the two target compounds have been investigated, and the results showed that the title compounds both have fluorescence performance and certain antioxidant activities against DPPH radical.

关键词： Schiff base 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde synthesis crystal structure property

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氢同位素吸附容量与吸附剂比表面积的关系

高等学校化学学报 2008年第4期29卷 775-778页

作者：褚效中徐继明江苏省低维材料化学重点建设实验室淮阴师范学院化学系淮安223300

采用容积法测量了77K下氢气与氘气在不同微孔与介孔分子筛吸附剂上的吸附容量与比表面积.结果表明,同类吸附剂上氢同位素的吸附容量与其比表面积之间存在较好的线性关系,这有力地证明了超临界温度下氢同位素吸附遵循单分子层吸附机理.... 详细信息

采用容积法测量了77K下氢气与氘气在不同微孔与介孔分子筛吸附剂上的吸附容量与比表面积.结果表明,同类吸附剂上氢同位素的吸附容量与其比表面积之间存在较好的线性关系,这有力地证明了超临界温度下氢同位素吸附遵循单分子层吸附机理.在相同的温度、压力和比表面积条件下,氢同位素气体在微孔分子筛上的吸附容量比介孔分子筛上的大,这是由于在吸附剂微孔内吸附势场叠加所致,并通过构建的吸附势模型,较好地解释了该实验结果.

关键词：氢同位素分子筛吸附势模型

考虑货主偏好的内支线集装箱班轮航线网络规划模型

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交通运输工程学报 2017年第3期17卷 131-140页

作者：杜剑赵旭计明军大连海事大学交通运输管理学院辽宁大连116026

为了增加内支线集装箱班轮航线网络的货运需求量,以最大船型限制、航线运营补贴与干支线配合为约束条件,以航线网络结构、适配船型与班期密度为决策变量,构建了考虑货主偏好的集装箱内支线班轮航线网络规划模型;为了评估规划航线对不同... 详细信息

为了增加内支线集装箱班轮航线网络的货运需求量,以最大船型限制、航线运营补贴与干支线配合为约束条件,以航线网络结构、适配船型与班期密度为决策变量,构建了考虑货主偏好的集装箱内支线班轮航线网络规划模型;为了评估规划航线对不同偏好货主的吸引力,在获得航线的集装箱运输时间与价格后,基于Logit模型计算了规划航线与市场现有航线的货主选择比例;设计了求解模型的智能启发式算法,在规划方案评价过程中计算了航次时间、航线成本、单箱运价与货运需求,在方案改善过程中调整了航线的挂靠港口与挂靠顺序;设定大连港为干线港口,渤海湾内12个港口为支线港口,规划了内支线集装箱班轮航线网络。计算结果表明:12个支线港共开设了7条航线,市场货运总需求为5 208TEU,规划航线的货运需求量为4 420TEU;规划航线的货主选择比例达到85%;无论货主偏好运输时间或成本,规划航线在各支线港的货主选择比例皆超过60%。可见,考虑货主偏好的内支线班轮航线网络规划模型是有效的;开设直达航线有助于吸引时间偏好货主;开设串挂航线与提高运营补贴有助于吸引成本偏好货主;采用货主选择过程代替到港时间窗约束会提升模型优化效果。

关键词：交通规划集装箱运输班轮航线网络规划货主偏好内支线班轮智能启发式算法

含gfp植物转基因表达载体的构建及在矮牵牛转基因不定根中的高效表达

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遗传 2008年第8期30卷 1069-1074页

作者：徐纪明向太和杭州师范大学生命与环境科学学院杭州310036

利用pBIN19、pGFP和pCHS质粒,成功构建了CaMV35S启动子驱动的gfp基因的植物转基因表达载体pBIN-35S-GFP,并导入野生型发根农杆菌K599。矮牵牛的转化实验表明,矮牵牛离体叶片被发根农杆菌K599(带pBIN-35S-GFP质粒)感染生根率达45%。对诱... 详细信息

利用pBIN19、pGFP和pCHS质粒,成功构建了CaMV35S启动子驱动的gfp基因的植物转基因表达载体pBIN-35S-GFP,并导入野生型发根农杆菌K599。矮牵牛的转化实验表明,矮牵牛离体叶片被发根农杆菌K599(带pBIN-35S-GFP质粒)感染生根率达45%。对诱导的不定根基因组DNA的PCR检测表明,不定根基因组中含有发根农杆菌K599Ri质粒中的rolB基因和外源gfp基因;转基因不定根在蓝色光激发下能发出强烈的绿色荧光,表明构建的转基因载体pBIN-35S-GFP能实现gfp基因的高效表达。该载体在CaMV35S启动子的两端各有一个多克隆位点,可以方便地进行启动子替换,用于研究不同启动子的功能。此外,该载体在gfp基因的5′端含有多克隆位点,在3′端含有EcoRⅠ和BsmⅠ两个单一酶切位点,可以方便地在5′端连接上目标基因,表达含GFP的融合蛋白,进行目标基因编码蛋白的亚细胞定位;也可以方便地切除gfp基因,连上需要的目的基因进行转化。

关键词：绿色荧光蛋白基因表达载体构建转基因不定根

Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

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Neural Regeneration Research 2025年第1期20卷 6-20页

作者： Xiu-Yun Zhao De-En xu ming-Lei Wu ji-Chuan Liu Zi-Ling Shi Quan-Hong Ma Department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina Department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response

Inhibitory effect of IGF-Ⅱ antisense RNA on malignant phenotype of hepatocellular carcinoma

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World Journal of Gastroenterology 2000年第2期6卷 266-267页

作者： Dong Hua Yang ming Qing Zhang jiang Du Chong xu Oiao ming Liang ji Fang Mao Han Rong Qin Zi Rong Fan Department of Gastroenterology,Zhujiang Hospital,the First Military Medical University,Guangzhou 510282,China Laboratory of Molecular Biology,Zhujiang Hospital,the First Military Medical University,Guangzhou,China Departrnent of Biochemistry,the Second Military Medical University,Shanghai,China 第一军医大学广东广州

INIRODUCTIONAccording to the therapeutic effect and strategy ofantisense RNA for hepatoccllular carcinoma(HCC),we have specifically synthesized partialcDNA of human insulin-like growth factor Ⅱ(IGF-Ⅱ)and constructed IGF-Ⅱ cDNA antisenseeukaryotic expression *** constructedvector was introduced into hepatoma cell lineSMMC-7721 to block the intrinsic IGF-Ⅱ*** biological behavior changes ofhepatoma cells were *** these

关键词： carcinoma hepatocellular insulin-like growth factor Ⅱ genes suppressor tumor RNA antisense liver neoplasms

Rat model for study of the essence of spleen deficiency and dampness in Chinese medicine

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Traditional Medicine Research 2018年第5期3卷 251-257页

作者： Xiao-Chun Han xu-ming ji Lin Liu Shuang Zhang Li Sun Qiu-jian Feng Shi-Jun Wang College of Traditional Chinese Medicine Shandong University of Traditional Chinese MedicineJinanChina Department of Special Examination Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinanChina

Objective:To explore the essence of spleen deficiency and dampness in Chinese medicine by successfully constructing a rat model with this ***:Rat models with the syndrome of dampness and spleen deficiency were established with the use of a high-fat,low-protein diet and excessive fatigue induced by loaded swimming.A total of 25 common clinical serological markers were *** T test,rank test,and partial least squares regression-discriminant analysis were used to analyze the ***:Total protein,albumin,motilin,interferon-γ,interleukin-2,immunoglobulin A,immunoglobulin G,and complement 3 levels in the model rats were lower than those in the control group(P=0.029,P=0.032,P<0.001,P<0.001,P<0.001,P<0.001,P<0.001,P<0.001,respectively).The serum creatinine,total cholesterol,aldosterone,antidiuretic hormone,gastrin,interleukin-4,somatostatin,atrial natriuretic peptide,and vasoactive intestinal peptide levels in the model group were higher than those in the control group(P<0.001,P=0.015,P<0.001,P<0.001,P<0.001,P<0.001,P<0.001,P<0.001,P<0.001,respectively).There was no statistical difference between the two groups in aspartate transaminase,alanine aminotransferase,globulin,albumin/globulin,blood urea nitrogen,high-density lipoprotein,and low-density *** model animal syndrome used two important variables in analysis with partial least squares regression-discriminant *** the same time,the two dimensions were difficult to distinguish for each biological ***:Spleen deficiency is often associated with *** index that represents spleen deficiency can also represent ***,immunoglobulins,and gastrointestinal hormones play a major causative role in both spleen deficiency and dampness.

关键词： Spleen deficiency Dampness Animal model

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乙酰丙酸的清洁合成及络合萃取法分离制备

现代化工 2014年第1期34卷 83-86页

作者：吴真徐继明孙勇徐宁戴本林淮阴师范学院江苏省生物质能与酶技术重点实验室江苏淮安223300 淮阴师范学院化学与化工学院江苏淮安223300 厦门大学能源研究院福建厦门361005

以Fe3+改性的ZSM-5X分子筛作催化剂,高温条件下利用生物质酶解糖液清洁合成平台化合物——乙酰丙酸,并以乙酰丙酸的产率为指标,应用响应面分析方法研究最佳的合成条件。以三辛胺(TOA)为萃取剂,正丁醇、磷酸三丁酯、仲辛醇等为溶剂进行... 详细信息

以Fe3+改性的ZSM-5X分子筛作催化剂,高温条件下利用生物质酶解糖液清洁合成平台化合物——乙酰丙酸,并以乙酰丙酸的产率为指标,应用响应面分析方法研究最佳的合成条件。以三辛胺(TOA)为萃取剂,正丁醇、磷酸三丁酯、仲辛醇等为溶剂进行萃取、水相反萃取、分离乙酰丙酸。合成实验结果表明,在催化剂质量为5 g,温度为200℃,反应时间为3.7 h条件下,乙酰丙酸的最大产率为42.76%。优化后的萃取条件为:选择V(正丁醇)/V(三辛胺)为99/1或V(磷酸三丁酯)/V(三辛胺)为99.5/0.5的萃取体系络合萃取乙酰丙酸,再用水相反萃取,可达到较好的分离效果。

关键词：乙酰丙酸分子筛催化剂酶解液络合萃取