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Pricking and penetrating moxibustion therapy in patients with refractory insomnia: a randomized and controlled clinical trial

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Journal of Traditional Chinese Medicine 2018年第5期38卷 754-762页

作者： Chen Yan gao xiyan Sun Cuiying School of Rehabilitation Medicine Henan University of Chinese Medicine Acupuncture and Massage College Third Affiliated Hospital of Henan University of Chinese Medicine

OBJECTIVE: To observe the clinical effect of pricking and penetrating moxibustion therapy on refractory ***: Totally 60 subjects were randomly divided into treatment group and control group, 30 in each group. The treatment group was treated with pricking and penetrating moxibustion therapy, the control group with penetrating moxibustion therapy, the treatment was given once every day, two groups of patients were treated 20 times,compared the efficacy, pinsburgh sleep quality index(PSQI) and Traditional Chinese Medicine symptom, safety evaluation between the two ***: Compared with 10, 20 times after the treatment, the effective rate of the treatment group(93.3%) higher than that of the control group(80.0%)(P < 0.05); Compared with beforetreatment, 20 times after treatment, the PSQI and TCM symptom pattern scores of the two groups were significantly decreased(P < 0.01); Compared with 10, 20 times after the treatment, the treatment group are better than the control group in improving the total score and the integral of PSQI(P <0.05 or P < 0.01); The treatment group are better than the control group in improving the TCM symptom pattern score, difficulty in going to sleep, palpitation, amnesia, fidget, sweating, impaired concentration(P < 0.01 or P < 0.05).CONCLUSION: The pricking and penetrating moxibustion therapy is safe and effective in the treatment of refractory insomnia and the treatment can improve the curative effect of the therapy that uses penetrating moxibustion only.

关键词： Sleep initiation and maintenance disorders Pricking and penetrating moxibustion therapy Randomized controlled trail

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Denitrification characteristics of a marine origin psychrophilic aerobic denitrifying bacterium

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Journal of Environmental Sciences 2011年第11期23卷 1888-1893页

作者： Haiyan Zheng Ying Liu Guangdong Sun xiyan gao Qingling Zhang Zhipei Liu State Key Laboratory of Microbial Resources Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China.

A psychrophilic aerobic denitrifying bacterium,strain S1-1,was isolated from a biological aerated filter conducted for treatment of recirculating water in a marine aquaculture *** S1-1 was preliminarily identified as Psychrobacter *** on the analysis of its 16S rRNA gene sequence,which showed 100% sequence similarity to that of Psychrobacter *** S1-1 grew well either in high nitrate or high nitrite conditions with a removal of 100% nitrate or 63.50% nitrite,and the total nitrogen removal rates could reach to 46.48% and 31.89%,*** results indicated that nitrate was mainly reduced in its logarithmic growth phase with a very low leve1 accumulation of nitrite,suggesting that the aerobic denitrification process of strain S1-1 occurred mainly in this *** GC-MS results showed that N 2 O was formed as the major intermediate during the aerobic denitrifying process of strain ***,factors affecting the growth of strain S1-1 and its aerobic denitrifying ability were also *** showed that the optimum aerobic denitrification conditions for strain S1-1 were sodium succinate as carbon source,C/N ratio15,salinity 10 g/L NaCl,incubation temperature 20°C and initial pH 6.5.

关键词： nitrogen removal aerobic denitrification marine environment low temperature Psychrobacter sp.S1-1

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Relative specificity of acupuncture reinforcing and reducing methods

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Journal of Traditional Chinese Medicine 2012年第3期32卷 488-493页

作者： xiyan gao Danyi Wang Ling gao Ronghui gao Henan TCM College Zhengzhou 450008 China China Academy of Chinese Medical Sciences1Beijing 100700 China /

OBJECTIVE:To probe the effects of acupuncture reinforcing and reducing methods on the human ***:Studied acupuncture reinforcing and reducing actions in the ancient literature,based on modern clinical and experimental studies,in combination with experience of acupuncture teaching and clinical ***:The key to the generation of reinforcing and reducing actions is not the acupuncture reinforcing and reducing methods themselves,but instead the functional state of the patient during the *** reinforcing and reducing methods act on the human body,a reinforcing-reducing effect is produced through regulation of Qi,indicating that the production of the reinforcing-reducing effect requires a certain ***,acupuncture does not produce the reinforcing-reducing effect under all conditions,but can produce a reinforcing effect in patients with deficiency syndrome and a reducing effect in patients with excess ***:Reinforcing and reducing methods each have therapeutic effects on both deficiency syndrome and excess syndrome,but a reinforcing method should be selected first for deficiency syndrome and a reducing method should be selected first for excess syndrome.

关键词： Acupuncture theray Reinforcing-reducing Relative specificity

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Correlation of continuous electroencephalogram with clinical assessment scores in acute stroke patients

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Neuroscience Bulletin 2012年第5期28卷 611-617页

作者： xiyan Xin Ying gao Hua Zhang Kegang Cao Yongmei Shi Department of Neurology Dongzhimen Hospital Beijing University of Chinese Medicine Beijing 100700 China

Objective To compare electroencephalogram （EEG） symmetry values between stroke patients with different 28-day outcomes, and to assess correlations between clinical characteristics and 28-day outcomes. Methods Twenty-two patients presenting with acute ischemic stroke and persistent neurological deficits at EEG recording were incrementally included. At 28 days after admission, the modified Rankin scale （mRS） was used to evaluate the outcomes, based on which the patients were divided into two a posteriori groups, mRS = 6 and mRS 〈6. Student＇s t-test was used to compare these two groups in terms of brain symmetry index （BSI）, National Institutes of Health stroke scale （NIHSS）, Glasgow coma scale （GCS） and acute physiology and chronic health evaluation II （APACHE II） assessed at admission. Then EEG parameters, NIHSS, GCS and APACHE II were correlated with the mRS. Results There were significant differences in BSI, NIHSS, GCS, and APACHE II between the two groups. Survivors had lower BSI, NIHSS and APACHE II, and higher GCS values, compared with patients who died within 28 days after admission. Besides, BSI at admission had a positive correlation with mRS at 28 days （r = 0.441, P = 0.040）. NIHSS and APACHE II were also correlated with mRS （r = 0.736, P 〈0.000 1; r = 0.667, P = 0.001, respectively）. GCS at admission had a negative correlation with mRS （r = 0.656, P = 0.001）. Conclusion A higher BSI predicts a poorer short-term prognosis for stroke patients. Acute EEG monitoring may be of prognostic value for 28-day outcomes. The early prediction of functional outcomes after stroke may enhance clinical management and minimize short-term mortality.

关键词： electroencephalography brain symmetry index stroke prognosis

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Curative effect of acupuncture and moxibustion on insomnia: a randomized clinical trial

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Journal of Traditional Chinese Medicine 2013年第4期33卷 428-432页

作者： xiyan gao Cuixiang Xu Peiyu Wang Shan Ren Yanli Zhou Xuguang Yang Ling gao College of Acupuncture and Massage Henan University of Traditional Chinese Medicine

OBJECTIVE: To observe the effect of acupuncture and moxibustion on insomnia and explore its mechanism. METHODS: One hundred and twenty patients were randomly divided into an experiment group and a control group. Sixty patients in the experiment group were treated once a day with acupuncture at Baihui (GV 20), Sishencong (EX-HN 1), Shenmai (BL 62), and Zhaohai (KI 6) and with moxibustion at Baihui (GV 20) and Sishencong (EX-HN 1). Sixty patients in the control group were acupunctured once a day at Shenmen (HT 7), Neiguan (PC 6), and Sanyinjiao (SP 6).The Pittsburgh Sleep Quality Index (PSQI) was used to compare sleep improvement between the two groups. RESULTS: The total effective rate was 87.7% in the experiment group and 76.3% in the control group. The PSQI scores and the total score were lower after treatment than before treatment in bothgroups. However, the reduction in the experiment group was greater than that in the control group in sleeping quality, time to fall asleep, sleeping disorder, and daytime function (P<0.05). CONCLUSION: Acupuncture and moxibustion at Baihui (GV 20), Sishencong (EX-HN 1), Shenmai (BL 62), and Zhaohai (KI 6) significantly improved insomnia symptoms in the experiment group compared with the control group.

关键词： Acupuncture Sleep initiation and maintenance disorders Treatment outcome Randomized clinical trialsc

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直喷柴油机低压缩比双壁面反射燃烧系统快速燃烧的试验研究

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汽车工程 2015年第6期37卷 631-636页

作者：郭鹏江高希彦大连理工大学内燃机研究所大连116024

本文除在先前对低压缩比直喷柴油机双壁面反射燃烧系统试验研究的基础上,扩展试验内容,以进一步验证该燃烧系统的优势和良好效果之外,着重对该燃烧系统的快速燃烧这一特征进行了试验研究。结果表明：采用该燃烧系统,在全工况范围内降低... 详细信息

本文除在先前对低压缩比直喷柴油机双壁面反射燃烧系统试验研究的基础上,扩展试验内容,以进一步验证该燃烧系统的优势和良好效果之外,着重对该燃烧系统的快速燃烧这一特征进行了试验研究。结果表明：采用该燃烧系统,在全工况范围内降低了气缸爆发压力和NOx排放,改善了低速油耗率和烟度排放,只是在高速区指示热效率降低,油耗率略有增加。通过外特性工况瞬时放热率在中高速区呈单峰趋势和累积放热率5%~70%对应的曲轴转角θ5~θ70范围内与原机有相同的燃烧速率,证实了低几何压缩比的双壁面反射燃烧系统仍具有快速燃烧的特征。

关键词：直喷柴油机双壁面反射燃烧系统瞬时放热率压缩比

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Discussion on the treatment of scapulohumeral periarthritis

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World Journal of Acupuncture-Moxibustion 2018年第2期28卷 73-78,86页

作者： xiyan gao Xiao LI Meilu DU Lihua WL Henan University of Chinese Medicine Zhengzhou 450008Henan ProvinceChina

The severity and location of scapulohumeral periarthritis should be identified for determining its treatment method： when the wei exterior is initially invaded by external pathogens for the first time, the location of disease is shallow, therefore, the shallow needling should be performed, which can contribute to diffusing and discharging pathogens of wei exterior. If pathogens had invaded for a long time, they can enter the ying level from wei level, so the acupuncture on ying level should be conducted to discharge the blood stasis and stagnation, thus removing the pathogenic qi and maintaining the healthy qi. If pathogens had invaded for a long time, the meridians and collaterals will be obstructed, and the penetration moxibustion method should be adopted to make the heat penetrate deeply, thereby achieving the effects of warming the meridians and expelling bi. The therapy should be chosen based on syndromes, so meridians can be dredged, and qi-blood can be harmonized, finally the disease will be cured. The precise determination of the location can ensure the success of manipulations. After the nature of disease is identified, targeted methods of acupuncture, bloodletting and fire needling can be performed for treatment of diseases, as a result, ＂normal physiological activities can be maintained＂.

关键词： Scapulohumeral periarthritis Wei level-needling Ying level-needling Cold bi

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“双壁面射流”燃烧系统性能的试验研究

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农业工程学报 2012年第9期28卷 57-63页

作者：郭鹏江高希彦于锋大连理工大学内燃机研究所大连116024

为了改善直喷柴油机的排放与经济性能,该文开发了一种直喷柴油机"双壁面射流"燃烧系统。通过试验的方法研究了燃烧室结构参数、喷油器结构参数、转速、负荷及喷油时刻等运行条件对"双壁面射流"燃烧系统燃烧过程的影响。试验结果表明:随... 详细信息

为了改善直喷柴油机的排放与经济性能,该文开发了一种直喷柴油机"双壁面射流"燃烧系统。通过试验的方法研究了燃烧室结构参数、喷油器结构参数、转速、负荷及喷油时刻等运行条件对"双壁面射流"燃烧系统燃烧过程的影响。试验结果表明:随转速的增加,着火始点向后推迟,缸压峰值呈现出先增大后减小的趋势,瞬时放热率峰值、缸内燃烧平均温度和累计放热量都降低;随负荷的增加,着火点提前,缸压峰值对应的曲轴转角向后推迟,缸压峰值、缸内燃烧平均温度和累计放热量都增加,总指示热效率随负荷的增加而降低。不同燃烧室结构参数和喷油器参数的"双壁面射流"燃烧系统燃烧持续期,在2100r/min的负荷特性中,小负荷主要受压缩比的影响,大负荷主要受预混合燃烧量的影响;总指示热效率主要受压缩比和壁面油膜生成量的影响;而NOx与碳烟排放受预混合燃烧量和贯穿度的影响。将"双壁面射流"燃烧系统静态供油提前角提前到18°CA BTDC,能实现扭矩点与功率点同为0.21BSU的低碳烟排放。

关键词：柴油机燃烧排放控制双壁面射流 NOx 指示热效率

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Cu污染条件下封闭循环水养虾系统的效能

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农业工程学报 2011年第2期27卷 248-254页

作者：程波刘鹰杨红生高喜燕中国科学院海洋研究所青岛266071 中国水产科学研究院北京100141 中国科学院微生物研究所北京100101

为获得Cu2+污染对封闭循环水养虾系统的影响,选用0.3 mg/L Cu2+浓度,研究其对系统中水质、对虾生长、存活及生物滤器水处理效能的影响。结果表明,经过84 d的试验,养殖水体中Cu2+质量浓度在系统水处理单元作用下降为(0.089±0.012)mg/L,... 详细信息

为获得Cu2+污染对封闭循环水养虾系统的影响,选用0.3 mg/L Cu2+浓度,研究其对系统中水质、对虾生长、存活及生物滤器水处理效能的影响。结果表明,经过84 d的试验,养殖水体中Cu2+质量浓度在系统水处理单元作用下降为(0.089±0.012)mg/L,对虾能正常生长和存活,0.3 mg/L Cu2+处理质量浓度对生物滤器的化学需要量(COD)、NH4-N和NO2-N去除率及滤器中异养细菌、氨氧化菌和亚硝酸盐氧化菌的数量不造成显著影响。处理系统对虾体内Cu质量分数为(42.91±6.10)mg/kg,与对照中质量分数(29.36±4.06)mg/kg相比,具有显著差异,但均在国家无公害食品水产品中有毒有害物质限量标准(Cu≤50 mg/kg)范围内。在0.3 mg/L Cu2+质量浓度污染下,封闭循环水养虾系统仍能提供较好的水质条件,获得较高的产量和较低的饵料转化率,所养对虾符合无公害水产品要求。

关键词：对虾水产养殖 Cu 污染生物滤器效能微生物数量

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数值仿真在泵阀参数优化中的应用

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排灌机械工程学报 2010年第1期28卷 63-67页

作者：高希彦王燕方武大连理工大学能源与动力工程学院辽宁大连116024

采用RNGk-ε湍流模型、动网格技术以及用户自定义程序,对往复泵泵阀的启闭过程进行了非定常数值仿真,得出了不同弹簧因素下、阀门从开启到关闭的过程中,阀芯的升程随时间的变化规律、阀的迟滞关闭时间以及阀芯落座的瞬时速度.仿真结果表... 详细信息

采用RNGk-ε湍流模型、动网格技术以及用户自定义程序,对往复泵泵阀的启闭过程进行了非定常数值仿真,得出了不同弹簧因素下、阀门从开启到关闭的过程中,阀芯的升程随时间的变化规律、阀的迟滞关闭时间以及阀芯落座的瞬时速度.仿真结果表明,在同时保证阀芯有较大的开启度和较短的滞后关闭时间时,弹簧刚度和预紧力因素之间存在着最佳组合:k=10 N/cm,f=15 N;同等地改变预紧力比改变弹簧刚度,对阀门的运动影响更大.设计了往复泵泵阀试验台;通过对往复泵进行性能测试,对不同弹簧预紧力下阀门升程进行了测定,验证了仿真结果的合理性.该仿真方法对往复泵泵阀参数优化具有一定的借鉴意义.

关键词：阀门弹簧刚度预紧力迟滞关闭

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