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Identification of novel mammalian viruses in tree shrews(Tupaia belangeri chinensis)

Zoological Research 2024年第2期45卷 429-438页

作者： Hong Zhou Ren-rong Tian xiu-rong wang Jin-Xuan Yang Yun-Xiao wang Ming-Liang Zhao Xu-Dong Zhang Yu-Hua Ma Long-Bao Lv Edward CHolmes Yong-Tang Zheng Wei-Feng Shi School of Clinical and Basic Medical Sciences Shandong First Medical University&Shandong Academy of Medical SciencesJi’nanShandong 250117China Key Laboratory of Emerging Infectious Diseases in Universities of Shandong Shandong First Medical University and Shandong Academy of Medical SciencesTaianShandong 271000China Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common DiseasesCenter for Biosafety Mega-ScienceKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China School of Public Health Shandong First Medical University&Shandong Academy of Medical SciencesJi’nanShandong 250117China National Resource Center for Non-Human Primates Kunming Primate Research CenterKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650107China Sydney Institute for Infectious Diseases School of Medical SciencesThe University of SydneySydneyNew South Wales 2006Australia Department of Infectious Diseases Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Shanghai Institute of Virology Shanghai Jiao Tong University School of MedicineShanghai 200025China

The Chinese tree shrew(Tupaia belangeri chinensis),a member of the mammalian order Scandentia,exhibits considerable similarities with primates,including humans,in aspects of its nervous,immune,and metabolic *** similarities have established the tree shrew as a promising experimental model for biomedical research on cancer,infectious diseases,metabolic disorders,and mental health ***,we used metatranscriptomic sequencing to analyze plasma,as well as oral and anal swab samples,from 105 healthy asymptomatic tree shrews to identify the presence of potential zoonotic *** total,eight mammalian viruses with complete genomes were identified,belonging to six viral families,including Flaviviridae,Hepeviridae,Parvovirinae,Picornaviridae,Sedoreoviridae,and ***,the presence of rotavirus was recorded in tree shrews for the first *** viruses-hepacivirus 1,parvovirus,and picornavirus-exhibited low genetic similarity(94%)to known viral *** analyses also revealed that the rotavirus and mammalian orthoreovirus identified in this study may be novel *** findings provide insights into the diverse viral spectrum present in captive Chinese tree shrews,highlighting the necessity for further research into their potential for crossspecies transmission.

关键词： Tree shrew(Tupaia belangeri chinensis) Meta-transcriptomic sequencing Mammalian viruses Genomic analysis

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Surface iodine and pyrenyl-graphdiyne co-modified Bi catalysts for highly efficient CO_(2) electroreduction in acidic electrolyte

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Nano Research 2024年第4期17卷 2381-2387页

作者： Min Zhang Juan wang Xin rong xiu-Li Lu Tong-Bu Lu MOE International Joint Laboratory of Materials Microstructure Institute for New Energy Materials and Low Carbon TechnologiesSchool of Materials Science and EngineeringTianjin University of TechnologyTianjin 300384China

CO_(2) electroreduction to formic acid/formate would contribute to alleviating the energy and climate *** work reports a Bi-based catalyst derived from the in-situ electroreduction of Bi_(2)O_(2)CO_(3) modified with iodine and pyrenyl-graphdiyne(PGDY)on the surface for efficient electroreduction of CO_(2) in acidic electrolyte,with a high partial current density of 98.71 mA·cm^(-2) and high Faradaic efficiency(FE)>90%over the potential range from^(-1).2 to-1.5 V *** hydrogen electrode(RHE),as well as the long-term operational stability over 240 h without degradation in H-type *** results and density function theory calculations show that the synergistic effect of surface iodine and PGDY is responsible for this active and extremely stable process of CO_(2) electroreduction via lowering the energy barriers for formation of*OCHO intermediate,suppressing the competitive HER by enhancing the concentration of both K+and CO_(2) at reaction interface,as well as preventing the dissolution and re-deposition of active Bi atoms on surface during catalytic *** work provides new insight into designing highly active and stable electrocatalysts for CO_(2) reduction.

关键词： CO_(2) reduction electrocatalysis Bi-based catalysts acidic electrolyte

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Clinical value of precise rehabilitation nursing in management of cerebral infarction

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World Journal of Clinical Cases 2024年第1期12卷 24-31页

作者： Ya-Na Xu xiu-Zhen wang Xiao-rong Zhang Department of Neurology Wuhan Fourth HospitalWuhan 430030Hubei ProvinceChina Department of Neurosurgery The First People's Hospital of Jiangxia DistrictWuhan City(Union Jiangnan Hospital of Huazhong University of Science and Technology)Wuhan 430200Hubei ProvinceChina

BACKGROUND Cerebral infarction,previously referred to as cerebral infarction or ischemic stroke,refers to the localized brain tissue experiencing ischemic necrosis or softening due to disorders in brain blood supply,ischemia,and *** precision rehabilitation nursing model for chronic disease management is a continuous,fixed,orderly,and efficient nursing model aimed at standardizing the clinical nursing process,reducing the wastage of medical resources,and improving the quality of medical *** To analyze the value of a precise rehabilitation nursing model for chronic disease management in patients with cerebral *** Patients(n=124)admitted to our hospital with cerebral infarction between November 2019 and November 2021 were enrolled as the study *** random number table method was used to divide them into a conventional nursing intervention group(n=61)and a model nursing intervention group(n=63).Changes in the nursing index for the two groups were compared after conventional nursing intervention and precise rehabilitation intervention nursing for chronic disease *** Compared with the conventional intervention group,the model intervention group had a shorter time to clinical symptom relief(P<0.05),lower Hamilton Anxiety Scale and Hamilton Depression Scale scores,a lower incidence of total complications(P<0.05),a higher disease knowledge mastery rate,higher safety and quality,and a higher overall nursing satisfaction rate(P<0.05).CONCLUSION The precision rehabilitation nursing model for chronic disease management improves the clinical symptoms of patients with cerebral infarction,reducing the incidence of total complications and improving the clinical outcome of patients,and is worthy of application in clinical practice.

关键词： Precise rehabilitation nursing model for chronic disease management Cerebral infarction Knowledge of disease Safety and quality

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Vibration Control of A Flexible Marine Riser System Subject to Input Dead Zone and Extraneous Disturbances

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China Ocean Engineering 2024年第2期38卷 271-284页

作者： ZHOU Li wang Guo-rong WAN Min School of Mechatronic Engineering Southwest Petroleum UniversityChengdu 610500China Energy Equipment Institute Southwest Petroleum UniversityChengdu 610500China National Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu 610500China

An observer-based adaptive backstepping boundary control is proposed for vibration control of flexible offshore riser systems with unknown nonlinear input dead zone and uncertain environmental *** control algorithm can update the control law online through real-time data to make the controller adapt to the environment and improve the control ***,based on the adaptive backstepping framework,virtual control laws and Lyapunov functions are designed for each *** direction interference observers are designed to track the timevarying boundary *** this basis,the inverse of the dead zone and linear state transformation are used to compensate for the original system and eliminate the adverse effects of the dead *** addition,the stability of the closed-loop system is proven by Lyapunov stability *** the system states are bounded,and the vibration offset of the riser converges to a small area of the initial ***,four examples of flexible marine risers are simulated in MATLAB to verify the effectiveness of the proposed controller.

关键词： adaptive backstepping control disturbance observer flexible marine riser input dead zone vibration control

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Transcriptional regulation in the development and dysfunction of neocortical projection neurons

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Neural Regeneration Research 2024年第2期19卷 246-254页

作者： Ningxin wang rong Wan Ke Tang Precise Genome Engineering Center School of Life SciencesGuangzhou UniversityGuangzhouGuangdong ProvinceChina

Glutamatergic projection neurons generate sophisticated excitatory circuits to integrate and transmit information among different cortical areas,and between the neocortex and other regions of the brain and spinal *** development of cortical projection neurons is regulated by certain essential events such as neural fate determination,proliferation,specification,differentiation,migration,survival,axonogenesis,and *** processes are precisely regulated in a tempo-spatial manner by intrinsic factors,extrinsic signals,and neural *** generation of correct subtypes and precise connections of projection neurons is imperative not only to support the basic cortical functions(such as sensory information integration,motor coordination,and cognition)but also to prevent the onset and progression of neurodevelopmental disorders(such as intellectual disability,autism spectrum disorders,anxiety,and depression).This review mainly focuses on the recent progress of transcriptional regulations on the development and diversity of neocortical projection neurons and the clinical relevance of the failure of transcriptional modulations.

关键词： autism spectrum disorders cognition differentiation excitatory circuits intellectual disability neocortex neurodevelopmental disorders projection neuron specification transcriptional regulation

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Explosion resistance performance of reinforced concrete box girder coated with polyurea:Model test and numerical simulation

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Defence Technology（防务技术） 2024年第3期33卷 1-18页

作者： Guangpan Zhou rong wang Mingyang wang Jianguo Ding Yuye Zhang School of Science Nanjing University of Science and TechnologyNanjing 210094JiangsuChina School of Mechanical Engineering Nanjing University of Science and TechnologyNanjing 210094JiangsuChina State Key Laboratory of Explosion and Impact and Disaster Prevention and Mitigation Army Engineering University of PLANanjing 210007JiangsuChina

To study the anti-explosion protection effect of polyurea coating on reinforced concrete box girder,two segmental girder specimens were made at a scale of 1:3,numbered as G(without polyurea coating)and PCG(with polyurea coating).The failure characteristics and dynamic responses of the specimens were compared through conducting explosion *** reliability of the numerical simulation using LS-DYNA software was verified by the test *** effects of different scaled distances,reinforcement ratios,concrete strengths,coating thicknesses and ranges of polyurea were *** results show that the polyurea coating can effectively enhance the anti-explosion performance of the *** top plate of middle chamber in specimen G forms an elliptical penetrating hole,while that in specimen PCG only shows a very slight local *** peak vertical displacement and residual displacement of PCG decrease by 74.8% and 73.7%,respectively,compared with those of specimen *** the TNT explosion with small equivalent,the polyurea coating has a more significant protective effect on reducing the size of *** the increase of TNT equivalent,the protective effect of polyurea on reducing girder displacement becomes more *** optimal reinforcement ratio,concrete strength,thickness and range of polyurea coating were also drawn.

关键词： Explosive load Explosion resistance performance Model test Polyurea Concrete box girder Numerical simulation

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GNN-based temporal knowledge reasoning for UAV mission planning systems

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The Journal of China Universities of Posts and Telecommunications 2024年第1期31卷 12-25页

作者： Chai rong Duan Xiaofang wang Lixuan School of Communications and Information Engineering Chongqing University of Posts and TelecommunicationsChongqing 400065China

Unmanned aerial vehicles(UAVs)are increasingly applied in various mission scenarios for their versatility,scalability and *** UAV mission planning systems(UMPSs),an efficient mission planning strategy is essential to meet the requirements of UAV ***,rapidly changing environments and unforeseen threats pose challenges to UMPSs,making efficient mission planning *** address these challenges,knowledge graph technology can be utilized to manage the complex relations and constraints among UAVs,missions,and *** paper investigates knowledge graph application in UMPSs,exploring its modeling,representation,and storage concepts and ***,the construction of a specialized knowledge graph for UMPS is ***,the paper delves into knowledge reasoning within UMPSs,emphasizing its significance in timely updates in the dynamic environment.A graph neural network(GNN)-based approach is proposed for knowledge reasoning,leveraging GNNs to capture structural information and accurately predict missing entities or relations in the knowledge *** relation reasoning,path information is also incorporated to improve the accuracy of *** account for the temporal dynamics of the environment in UMPS,the influence of timestamps is captured through the attention *** effectiveness and applicability of the proposed knowledge reasoning method are verified via simulations.

关键词： unmanned aerial vehicle mission planning knowledge graph knowledge reasoning graph neural network

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A bifunctional POM-based Cu-viologen complex with mixed octamolybdate clusters for rapid oxidation desulfurization and effective photogeneration of hydrogen

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Rare Metals 2024年第1期43卷 236-246页

作者： Lin Yang Zhong Zhang Chao-Nan Zhang xiu-Li wang College of Chemistry and Materials Engineering Bohai UniversityJinzhou 121013China Professional Technology Innovation Center of Liaoning Province for Conversion Materials of Solar Cell Bohai UniversityJinzhou 121013China

The design and synthesis of catalysts for the oxidation desulfurization and production of hydrogen are extremely important for solving environmental pollution and energy ***,a novel bifunctional [α-Mo_(8)O_(26)]^(4-)/[β-Mo_(8)O_(26)]^(4-)-based Cu-viologen complex H_(4)[Cu_(2)~ⅠCl_(2)(Hbcbpy)_(4)] [α-Mo_(8)O_(26)] [β-Mo8O_(26)]·H_(2)O(BHU-2,Hbcbpy=1-(4-carboxybenzyl)-4,4'-bipyridinium) was synthesized and characterized by single-crystal X-ray diffraction(XRD),infrared radiation spectra,powder X-ray diffraction(PXRD) and X-ray photoelectron spectroscopy(XPS) *** structural characteristic of BHU-2 is the presence of two types of octamolybdate clusters [α-Mo_(8)O_(26)]^(4-)/[β-Mo_(8)O_(26)]^(4-)and a new binuclear Cu~Ⅰ-Hbcbpy complex linked by Cl-bridges[Cu_(2)ⅠCl_(2)(Hbcbpy)_(4)]^(4+).BHU-2 as a heterogeneous catalyst exhibits excellent activities to the oxidation desulfurization and photocatalytic hydrogen *** room temperature,BHU-2 can catalyze 96% conversion of methyl phenyl sulfide with 98% selectivity,and the process obeys the pseudo-first-order reaction kinetic with the half-life of9.6 *** notorious 2-chloroethyl ethyl sulfide can achieve 99% conversion with 98% selectivity within only1 min at the presence of BHU-2,and the turnover frequency(TOF) is up to 7400 h^(-1).BHU-2 also exhibits high catalytic activity for the oxidation of other aromatic and aliphatic thioethers within short time at room ***,BHU-2 shows a high catalytic activity for visible-light-driven hydrogen evolution with an H_(2) evolution rate of 1677.85 μmol·g^(-1)·h^(-1) within 10 ***,the catalytic activities do not decrease evidently after three cycles,revealing the prominent structural stability and recyclability.

关键词： Polyoxometalate Metal-organic complex Viologen Oxidation desulfurization Photocatalytic hydrogen production

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Analysis on Genetic Diversity and Genetic Basis of the Main Sesame Cultivars Released in China

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Agricultural Sciences in China 2011年第4期10卷 509-518页

作者： ZHANG Yan-xin SUN Jian ZHANG xiu-rong wang Lin-hai CHE Zhuo Oil Crop Research Institute Chinese Aeademy of Agrieultural Sciences~Key Laboratory of Oil Crop Biology Ministry of Agriculture Wuhan430062 P.R. China

SRAP （sequence-related amplified polymorphism） was used for the analysis of 67 sesame （Sesamum indicum L.） cultivars widely used in Chinese sesame major production areas from 1950 to 2007. A total of 561 bands were amplified using 21 SRAP random primer pairs, with 265 of them were polymorphic, resulting in a polymorphism ratio of 47.2%. The total bands and polymorphism amplified by each primer pair averaged 26.7 and 12.6, respectively. The average genetic similar coefficient and genetic distance of the 67 cultivars were 0.9104 and 0.0706, respectively, indicating limited genetic diversity and narrow genetic basis. Comparative analysis on genetic similarity and genetic distance of different classified cultivars showed that the difference of average genetic similarity coefficient and genetic distance between the landraces and cultivars bred through crosses reached significant levels （P=0.01）, with the genetic basis of landraces wider than that bred cultivars. The genetic basis of cultivars used in 1990-2007 was more narrow than that of cultivars from 1950 to 1969 and from 1970 to 1989, with the differences of average genetic similarity coefficient and genetic distance reached 0.01 significant level. The genetic basis of Chinese sesame main cultivars is relatively narrow, and the genetic basis of cultivars developed through crosses in recent years is narrower than history cultivars.

关键词： sesame (Sesamum indicum L.) cultivars SRAP genetic diversity genetic basis

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On the superconvergence of a WG method for the elliptic problem with variable coefficients

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Science China Mathematics 2024年第8期67卷 1899-1910页

作者： Junping wang Xiaoshen wang xiu Ye Shangyou Zhang Peng Zhu Division of Mathematical Sciences National Science FoundationAlexandriaVA 22314USA Department of Mathematics University of Arkansas at Little RockLittle RockAR 72204USA Department of Mathematical Sciences University of DelawareNewarkDE 19716USA College of Data Science Jiaxing UniversityJiaxing 314001China

This article extends a recently developed superconvergence result for weak Galerkin(WG)approximations for modeling partial differential equations from constant coefficients to variable *** superconvergence features a rate that is two orders higher than the optimal-order error estimates in the usual energy and L^(2)*** extension from constant to variable coefficients for the modeling equations is highly *** underlying technical analysis is based on a sequence of projections and *** results confirm the superconvergence theory for second-order elliptic problems with variable coefficients.

关键词： weak Galerkin finite element methods superconvergence second-order elliptic problems stabilizerfree

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