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Successful outcomes of unilateral vs bilateral pedicle screw fixation for lumbar interbody fusion:A meta-analysis with evidence grading

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World Journal of Clinical Cases 2022年第36期10卷 13337-13348页

作者： Lei Sun Ai-Xian Tian Jian-xiong ma Xin-Long ma Orthopedic Research Institute Tianjin HospitalTianjin UniversityTianjin 300050China

BACKGROUND Whether it’s better to adopt unilateral pedicle screw(UPS)fixation or to use bilateral pedicle screw(BPS)one for lumbar degenerative diseases is still controversially *** To make a comparison between UPS and BPS fixation as to how they work efficaciously and safely in patients suffering from lumbar degenerative *** We have searched a lot in the databases through 2020 with index terms such as“unilateral pedicle screw fixation”and“bilateral pedicle screw fixation.”Only randomized controlled trials and some prospective cohort studies could be found,yielding 15 *** intervention was unilateral pedicle screw fixation;Primarily We’ve got outcomes of complications and fusion ***,we’ve achieved outcomes regarding total blood loss,operative time,as well as length of *** were installed and utilized for subgroup analysis,analyzing forest plots,sensitivity,heterogeneity,forest plots,publication bias,and risk of *** Fifteen previous cases of study including 992 participants have been involved in our *** had slightly lower effects on fusion rate[relative risk(RR)=0.949,95%CI:0.910 to 0.990,P=0.015],which contributed mostly to this metaanalysis,and similar complication rates(RR=1.140,95%CI:0.792 to 1.640,P=0.481),Δvisual analog scale[standard mean difference(SMD)=0.178,95%CI:-0.021 to 0.378,P=0.080],andΔOswestry disability index(SMD=-0.254,95%CI:-0.820 to 0.329,P=0.402).In contrast,an obvious difference has been observed inΔJapanese Orthopedic Association(JOA)score(SMD=0.305,95%CI:0.046 to 0.563,P=0.021),total blood loss(SMD=-1.586,95%CI:-2.182 to-0.990,P=0.000),operation time(SMD=-2.831,95%CI:-3.753 to-1.909,P=0.000),and length of hospital stay(SMD=-0.614,95%CI:-1.050 to-0.179,P=0.006).CONCLUSION Bilateral fixation is more effective than unilateral fixation regarding fusion rate after lumbar interbody ***,JOA,operation time,total blood loss,as well as length of stay were improve

关键词： Unilateral pedicle screw fixation Bilateral pedicle screw fixation Meta-analysis Spinal fusion surgery Discectomy Lumbar interbody fusion

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Development of a PC-based Open Architecture Software-CNC System

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Chinese Journal of Aeronautics 2007年第3期20卷 272-281页

作者： ma xiong-bo HAN Zhen-yu WANG Yong-zhang FU Hong-ya School of Electromechanical Engineering Harbin Institute of Technology Harbin 150001 China

As a key te..hnology in the field of advanced manufacturing, an open architecture controller is studied. In order to develop an open architecture software-CNC system on personal computer （PC） according to open modular architecture controllers （OmaC）. First, the software and hardware platform is chosen and software realization methodology for the CNC system is determined. Second, static modeling methods of an open architecture controller inclusive of object-oriented （OO） programming technology, dynamic link library （DLL） technology and system modules partition are investigated. Third, the dynamical behavioral modeling and the data flow representation of open architecture controller are discussed, which are both described in hierarchy fmite state machine （FSM） model. Fourth, a reusable software module model is established to develop software function module library. Finally, a 3-axis milling machine tool test-bed, named for HIT-CNC, is successfully designed by means of the constructed software function module library and the system configuring method. The experimental results show that, besides increasing the degree of reusability and openness, application of above-mentioned method- ology leads to significant decrease of development time as well as maintenance cost.

关键词： open architecture controller PC soflware-CNC behavioral model OmaC machine tool

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The microbiome and autoimmunity: a paradigm from the gut–liver axis

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Cellular & Molecular Immunology 2018年第6期15卷 595-609页

作者： Bo Li Carlo Selmi Ruqi Tang ME Gershwin xiong ma Division of Gastroenterology and Hepatology Key Laboratory of Gastroenterology and HepatologyMinistry of HealthState Key Laboratory for Oncogenes and Related GenesRenji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai Institute of Digestive DiseaseShanghai 200001China Division of Rheumatology and Clinical Immunology Humanitas Research HospitalRozzanoItaly BIOMETRA Department University of Milan MilanItaly Division of Rheumatology Department of MedicineAllergy and Clinical ImmunologyUniversity of California at DavisDavisCAUSA

Microbial cells significantly outnumber human cells in the body,and the microbial flora at mucosal sites are shaped by environmental factors and,less intuitively,act on host immune responses,as demonstrated by experimental data in germ-free and gnotobiotic *** understanding of this link stems from the established connection between infectious bacteria and immune tolerance breakdown,as observed in rheumatic fever triggered by Streptococci via molecular mimicry,epitope spread and bystander *** availability of high-throughput techniques has significantly advanced our capacity to sequence the microbiome and demonstrated variable degrees of dysbiosis in numerous autoimmune diseases,including rheumatoid arthritis,type 1 diabetes,multiple sclerosis and autoimmune liver *** remains unknown whether the observed differences are related to the disease pathogenesis or follow the therapeutic and inflammatory changes and are thus mere *** fact,there are only limited data on the molecular mechanisms linking the microbiota to autoimmunity,and microbial therapeutics is being investigated to prevent or halt autoimmune *** a putative mechanism,it is of particular interest that the apoptosis of intestinal epithelial cells in response to microbial stimuli enables the presentation of self-antigens,giving rise to the differentiation of autoreactive Th17 cells and other T helper *** comprehensive review will illustrate the data demonstrating the crosstalk between intestinal microbiome and host innate and adaptive immunity,with an emphasis on how dysbiosis may influence systemic *** particular,a gut–liver axis involving the intestinal microbiome and hepatic autoimmunity is elucidated as a paradigm,considering its anatomic and physiological connections.

关键词： autoimmunity autoimmune liver disease dysbiosis microbiome

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Inversion-based attenuation compensation with dip constraint

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Petroleum Science 2022年第2期19卷 543-553页

作者： xiong ma Li-Li Huo Guo-Fa Li Hao Li Qing-Long Meng School of Geophysics China University of Petroleum-BeijingState Key Lab of Petroleum Resources and ProspectingKey Lab of Geophysical Exploration of CNPCChangping102249BeijingChina Exploration and Development Research Institute Jidong OilfieldChina National Petroleum CorporationTangshanHebei 063000China Exploration and Development Research Institute Dagang OilfieldChina National Petroleum CorporationTianjin300280China

Instability is an inherent problem with the attenuation compensation methods and has been partially relieved by using the inverse ***,the conventional inversion-based attenuation compensation approaches ignore the important prior information of the seismic ***,the compensated result appears to be distorted spatial continuity and has a low signal-to-noise ratio(S/N).To alleviate this issue,we have incorporated the seismic dip information into the inversion framework and have developed a dip-constrained attenuation compensation(DCAC)*** seismic dip information,calculated from the poststack seismic data,is the key to construct a dip constraint *** from the introduction of the seismic dip constraint,the DCAC approach maintains the numerical stability and preserves the spatial continuity of the compensated *** and field data examples demonstrate that the proposed method can not only improve seismic resolution,but also protect the continuity of seismic data.

关键词： Attenuation compensation Instability Inverse scheme Seismic dip Seismic resolution Spatial continuity

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Successful treatment in one myelodysplastic syndrome patient with primary thrombocytopenia and secondary deep vein thrombosis:A case report

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World Journal of Clinical Cases 2022年第14期10卷 4640-4647页

作者： Wen-Bin Liu Jian-xiong ma Hong-Xuan Tong Department of Hematology The First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310006Zhejiang ProvinceChina The Second Clinical Medical College Zhejiang Chinese Medical UniversityHangzhou 320000Zhejiang ProvinceChina Institute of Basic Theory for Chinese Medicine China Academy of Chinese Medical SciencesBeijing 100700China

BACKGROUND The contradictory process of coagulation and anticoagulation maintains normal physiological function,and platelets(PLTs)play a key role in hemostasis and *** severe thrombocytopenia and deep vein thrombosis(DVT)occur simultaneously,the physician will be confronted with a great challenge,especially when interventional thrombectomy *** SUMmaRY We describe a 52-year-old woman who suffered from myelodysplastic syndrome with severe thrombocytopenia and protein S deficiency with right lower extremity *** this patient,the treatment of DVT was associated with numerous contradictions due to severe thrombocytopenia,especially when interventional thrombectomy was not ***,fondaparinux sodium effectively alleviated the thrombus status of the patient and gradually decreased the D-dimer *** addition,no increase in bleeding was *** application of eltrombopag stimulated the maturation and differentiation of megakaryocytes and increased the peripheral blood PLT *** clinical symptoms of DVT in the right lower extremities in this patient significantly *** patient resumed daily life activities,and the treatment effects were independent of PLT *** This is a contradictory and complex case,and fondaparinux sodium and eltrombopag may represent a good choice for the treatment of DVT in patients with severe thrombocytopenia.

关键词： Thrombocytopenia Deep vein thrombosis Fondaparinux sodium Thrombophilia Myelodysplastic syndrome Eltrombopag Case report

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不同生长年限唐古特大黄根部土壤中细菌群落结构及多样性

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中国野生植物资源 2024年第4期43卷 68-77页

作者：刘汉成董刚侯明杰马雄甘肃民族师范学院化学与生命科学系甘肃合作747000

目的:明晰种植唐古特大黄对土壤微生物群落结构的影响。方法:采用高通量测序技术,分析不同生长年限(1~4年)唐古特大黄根部不同深度(1~20 cm、21~40 cm和41~60 cm)土壤中细菌群落结构特征。结果:在不同生长年限唐古特大黄根部土壤中共获... 详细信息

目的:明晰种植唐古特大黄对土壤微生物群落结构的影响。方法:采用高通量测序技术,分析不同生长年限(1~4年)唐古特大黄根部不同深度(1~20 cm、21~40 cm和41~60 cm)土壤中细菌群落结构特征。结果:在不同生长年限唐古特大黄根部土壤中共获得2080个细菌操作分类单元(OTU),隶属于28门84纲172目263科441属480种。变形杆菌门(Proteobacteria)、酸杆菌门(Acidobacteria)、放线菌门(Actinobacteria)、绿弯菌门(Chloroflexi)和芽单胞菌门(Gemmatimonadetes)是唐古特大黄根部土壤中相对丰度排名前5的优势类群,相对丰度之和达到0.80以上;mantel检验结果表明,土壤碱解氮、土壤微生物量氮(MBN)和土壤微生物量磷(MBP)含量及硝酸还原酶、纤维素酶和蔗糖酶活性对细菌群落结构影响极显著(P<0.01);土壤全磷、速效钾含量和过氧化氢酶活性对细菌群落结构影响显著(P<0.05)。受土壤理化因子、微生物量和酶活性的影响,细菌数量和多样性指数随唐古特大黄生长年限的增加呈现出先减少后增加的“马鞍型”趋势,在生长第3年时最低。NMDS分析结果显示唐古特大黄生长第3、4年时,第2土层和第3土层中细菌群落结构与其他样品存在明显差异。FAPROTAX生态功能分组中,化能异养型菌类丰度最高,达24.0%~32.0%,需氧异养型类群次之,占20.7%~28.2%,起硝化作用的菌类相对丰度约为12.5%~18.1%。结论:随着唐古特大黄生长年限的增加,土壤中细菌群落结构和功能类群发生了演替。

关键词：唐古特大黄土壤细菌群落结构土壤理化因子

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Gut microbiome,liver immunology,and liver diseases

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Cellular & Molecular Immunology 2021年第1期18卷 4-17页

作者： Rui Wang Ruqi Tang Bo Li xiong ma Bernd Schnabl Herbert Tilg Division of Gastroenterology and Hepatology Key Laboratory of Gastroenterology and HepatologyMinistry of HealthState Key Laboratory for Oncogenes and Related GenesRenji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai Institute of Digestive Disease145 Middle Shandong Road200001 ShanghaiChina Department of Medicine University of CaliforniaSan DiegoLa JollaCAUSA Department of Medicine VA San Diego Healthcare SystemSan DiegoCAUSA Department of Internal Medicine I GastroenterologyHepatologyEndocrinology&MetabolismMedical University InnsbruckInnsbruckAustria

The gut microbiota is a complex and plastic consortium of microorganisms that are intricately connected with human *** liver is a central immunological organ that is particularly enriched in innate immune cells and constantly exposed to circulating nutrients and endotoxins derived from the gut *** delicate interaction between the gut and liver prevents accidental immune activation against otherwise harmless *** on the interplay between the gut microbiota and liver has assisted in understanding the pathophysiology of various liver *** immense importance is the step from high-throughput sequencing(correlation)to mechanistic studies(causality)and therapeutic ***,we review the gut microbiota,liver immunology,and the interaction between the gut and *** addition,the impairment in the gut-liver axis found in various liver diseases is reviewed here,with an emphasis on alcohol-associated liver disease(ALD),nonalcoholic fatty liver disease(NAFLD),and autoimmune liver disease(AILD).On the basis of growing evidence from these preclinical studies,we propose that the gut-liver axis paves the way for targeted therapeutic modalities for liver diseases.

关键词： Gut-liver axis Alcohol liver disease Nonalcoholic fatty liver disease Autoimmune liver disease Microbiome

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Monophase-homointerface electrodes intrinsically stabilize high-voltage all-solid-state batteries

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Science China Chemistry 2024年第5期67卷 1729-1739页

作者： Xiaolin xiong Xianguo ma Tianshi Lv Liquan Chen Liumin Suo Beijing National Laboratory for Condensed matter Physics Institute of PhysicsChinese Academy of ScienceBeijing 100190China Center of materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

The electrochemical stability and contact reliability of heterointerfaces between the solid electrolyte(SE) and electrode are critical for all-solid-state batteries(ASSBs), particularly much more challenging for high-voltage ASSBs, owing to the limited thermodynamically electrochemical window and mechanical inflexibility of SE, aggravating interfacial side reactions and contact failure. Considering all those issues originating from intrinsic heterogeneity in physicochemical features between the cathode material and SE, we are thinking about simplifying the heterointerfaces into a homointerface as a permanent cure to solve all electrochemical-mechanical interfacial failure. Herein, we propose monophase cathodes to construct thermodynamically stable all-in-one homointerfaces in ASS electrodes, removing unstable heterointerfaces by excluding SEs and intrinsically eliminating the Li chemical potential gap to avoid the formation of lithium-depleted space-charge layer and highly resistive mixed ion–electron conductor interphase. Our conception is successfully validated in the layered transition-metal oxide cathodes, which display outstanding stability no matter the MH-LiCoO_(2) cathode charging to 4.7 V or MH-Li_(1.2)Mn_(0.54)Ni_(0.13)-Co_(0.13)O_(2) cathode charging to 5.3 V. It is undeniable that our current version of above-illustrated MH-cathodes would bring out some new challenges for the practical application due to abandoning the SE. However, we believe our work also offers a brandnew direction to ultimately address the electrochemical–mechanical interfacial issues that would be promising for high-energy ASSBs with more discoveries of advanced monophase cathodes in the future.

关键词： monophase-homointerface electrode high-voltage all-solid-state batteries electrochemical-mechanical interfacial issue

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Preparation of luminescent polystyrene microspheres via surface-modified route with rare earth(Eu^(3+) and Tb^(3+))complexes linked to 2,2'-bipyridine

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Rare Metals 2015年第8期34卷 590-594页

作者： Zhen-xiong ma Qi-Tao Zhang Jun-Liang Liu Chang-Hao Yan Ming Zhang Teruhisa Ohno School of Chemistry and Chemical Engineering Yangzhou University Department of Applied Chemistry Faculty of EngineeringKyushu Institute of Technology School of Chemical Engineering Yangzhou Polytechnic Institute

Luminescent polystyrene microspheres were easily fabricated from poly(styrene-co-methacrylic acid)and aqueous RE(III) chloride solution(RE=Eu, Tb) in the presence of 2,20-bipyridine as second ligand. The negative charges of carboxyl groups on the surface of microspheres coordinated with rare earth ions at first, such as complexes covalently linked to 2,20-bipyridine, resulting in strong photoluminescence. Various methods, including transmission electron microscope(TEM), scanning electron microscope(SEM), energy dispersive spectroscopy(EDS),Fourier transform infrared spectroscopy(FT-IR), and fluorescence spectrophotometer, were used to characterize the resultant polystyrene composite microspheres. This work highlights the idea that it is facile to synthesis luminescent microspheres by surface-modified method directly.

关键词： Luminescent Polystyrene Terbium Europium 2,2’-bipy

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不同生长年限唐古特大黄根部土壤中微生物量及酶活性变化规律研究

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中国野生植物资源 2024年第3期43卷 44-50页

作者：刘汉成陈庆圆董刚侯明杰马雄甘肃民族师范学院化学与生命科学系甘肃合作747000

目的:明晰种植唐古特大黄对土壤微生态的影响。方法:利用常规测定方法研究不同生长年限唐古特大黄根部土壤中微生物量和酶活性的变化规律。结果:土壤微生物量碳(MBC)、微生物量氮(MBN)和微生物量磷(MBP)含量随着唐古特大黄生长年限的增... 详细信息

目的:明晰种植唐古特大黄对土壤微生态的影响。方法:利用常规测定方法研究不同生长年限唐古特大黄根部土壤中微生物量和酶活性的变化规律。结果:土壤微生物量碳(MBC)、微生物量氮(MBN)和微生物量磷(MBP)含量随着唐古特大黄生长年限的增加而表现出“马鞍型”变化趋势,同一生长年限的唐古特大黄根部土壤微生物量与土壤深度呈极显著负相关(P <0.01);MBC/MBN值在8.85%~18.94%之间,说明唐古特大黄根部土壤已向“真菌型”转变。MBC/SOC、MBN/TN和MBP/TP值均低于植被覆盖良好区域。同一生长年限的唐古特大黄根部土壤酶活性随土壤深度增加而降低;在不同生长年限的唐古特大黄间,纤维素酶活性随着唐古特大黄生长年限的增加而降低;蛋白酶和硝酸还原酶活性随唐古特大黄生长年限增加也呈“马鞍型”变化趋势;过氧化氢酶活性随唐古特大黄生长年份增加而增高。结论:连续种植唐古特大黄能够对土壤微生物群落结构产生影响,一方面增加了根部土壤真菌数量,另一方面根部土壤积累过氧化氢类物质,可能导致唐古特大黄根系易发生病害或损伤。因此,研究认为唐古特大黄在青藏高原东北缘最适生长年限为4年。

关键词：唐古特大黄土壤微生物量土壤酶

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