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Rhizosphere microbial markers (micro-markers): A new physical examination indicator for traditional Chinese medicines

第40届中国控制会议

作者： Hao Xu xinyan zhang Ying Liang Research and Development Center of System Simulation Technology Beijing Institute of Control and Electronics Technology

In view of the existing hardware-in-the-loop simulation（HILS） test system is customized design,there are many problems,such as long development cycle,consumption of resources,difficult to transplant and expand,*** research of HILS universal technology is carried out,and a general platform of HILS for integrated design is designed and *** can provide an integrated organizational structure and universal support platform for HILS,realize the rapid construction of the HILS test system,and effectively improve the portability and scalability of the HILS test system.

关键词： general platform hardware-in-the-loop simulation integrated design

来源： cnki会议评论

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Chinese Herbal Medicines 2024年第2期16卷 180-189页

作者： Kailin Yang Yaping Zheng Kangmeng Sun xinyan Wu Zheng zhang Chunnian He Peigen Xiao Institute of Medicinal Plant Development Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100193China Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine Ministry of EducationBeijing 100193China

Rhizosphere microorganisms,as one of the most important components of the soil microbiota and plant holobiont,play a key role in the medicinal plant-soil ecosystem,which are closely related to the growth,adaptability,nutrient absorption,stress tolerance and pathogen resistance of host *** recent years,with the wide application of molecular biology and omics technologies,the outcomes of rhizosphere microorganisms on the health,biomass production and secondary metabolite biosynthesis of medicinal plants have received extensive ***,whether or to what extent rhizosphere microorganisms can contribute to the construction of the quality evaluation system of Chinese medicinal materials is still *** on the significant role of rhizosphere microbes in the survival and quality formation of medicinal plants,this paper proposed a new concept of rhizosphere microbial markers(micro-markers),expounded the relevant research methods and ideas of applying the new concept,highlighted the importance of micro-markers in the quality evaluation and control system of traditional Chinese medicines(TCMs),and introduced the potential value in soil environmental assessment,plant pest control and quality assessment of *** provides reference for developing ecological planting of TCMs and ensuring the production of high quality TCMs by regulating rhizosphere microbial communities.

关键词： physical examination indicator quality evaluation quality formation of medicinal plants rhizosphere microorganisms rhizosphere microbial markers

外周血及尿液中相关指标在中老年早期糖尿病肾病中的研究

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临床血液学杂志 2021年第8期34卷 564-567页

作者：张新研辽宁省抚顺市中医院检验科辽宁抚顺113008

目的:分析外周血同型半胱氨酸(Hcy)、胱抑素C(CysC)、超氧化物歧化酶(SOD)及尿视黄醇结合蛋白(RBP)、白蛋白(ALB)在中老年早期糖尿病肾病(DKD)鉴别诊断中的应用。方法:将2017年1月—2020年5月收治的84例2型糖尿病(DM)患者。按照患者24 ... 详细信息

目的:分析外周血同型半胱氨酸(Hcy)、胱抑素C(CysC)、超氧化物歧化酶(SOD)及尿视黄醇结合蛋白(RBP)、白蛋白(ALB)在中老年早期糖尿病肾病(DKD)鉴别诊断中的应用。方法:将2017年1月—2020年5月收治的84例2型糖尿病(DM)患者。按照患者24 h尿蛋白排泄率的不同分为单纯DM组(44例)和DKD组(40例),另取同期来院体检的健康者41例为对照组,比较3组受试者外周血Hcy、CysC、SOD及尿液中RBP、ALB水平。结果:外周血Hcy、CysC及尿液RBP、ALB水平DKD组>DM组>对照组,SOD水平DKD组Ⅱ期>Ⅰ期,SOD水平Ⅲ期<Ⅱ期<Ⅰ期,差异有统计学意义(P<0.05)。血清Hcy、CysC水平及尿液RBP、ALB水平均与肾小球滤过率(GFR)水平呈负相关,SOD与GFR水平呈正相关(P<0.05)。外周血Hcy、CysC、SOD及尿液RBP、ALB联合诊断的敏感性及特异性明显升高。结论:外周血Hcy、CysC、SOD及尿液RBP、ALB联合检测对于早期DKD有很好的诊断价值,可以较为灵敏地反映患者的肾功能损伤。

关键词：糖尿病肾病同型半胱氨酸胱抑素C 尿视黄醇结合蛋白白蛋白

Optimizing high-coordination shell of Co-based single-atom catalysts for efficient ORR and zinc-air batteries

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Journal of Energy Chemistry 2024年第8期95卷 306-314,I0007页

作者： Yugang Qi Qing Liang Kexin Song xinyan Zhou Meiqi Liu Wenwen Li Fuxi Liu Zhou Jiang Xu Zou Zhongjun Chen Wei zhang Weitao Zheng Key Laboratory of Automobile Materials MOE School of Materials Science&Engineering Electron Microscopy Centerand International Center of Future ScienceJilin Provincial International Cooperation Key Laboratory of High-Efficiency Clean Energy MaterialsJilin UniversityChangchun 130012JilinChina Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

Atom-level modulation of the coordination environment for single-atom catalysts(SACs)is considered as an effective strategy for elevating the catalytic *** the MNxsite,breaking the symmetrical geometry and charge distribution by introducing relatively weak electronegative atoms into the first/second shell is an efficient way,but it remains challenging for elucidating the underlying mechanism of ***,a practical strategy was reported to rationally design single cobalt atoms coordinated with both phosphorus and nitrogen atoms in a hierarchically porous carbon derived from metal-organic frameworks.X-ray absorption spectrum reveals that atomically dispersed Co sites are coordinated with four N atoms in the first shell and varying numbers of P atoms in the second shell(denoted as Co-N/P-C).The prepared catalyst exhibits excellent oxygen reduction reaction(ORR)activity as well as zinc-air battery *** introduction of P atoms in the Co-SACs weakens the interaction between Co and N,significantly promoting the adsorption process of ^(*)OOH,resulting in the acceleration of reaction kinetics and reduction of thermodynamic barrier,responsible for the increased intrinsic *** discovery provides insights into an ultimate design of single-atom catalysts with adjustable electrocatalytic activities for efficient electrochemical energy conversion.

关键词： Electrocatalytic Oxygen reduction reaction Single atom catalyst Shell coordination optimization

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串行伯努利生产线的实时维护决策控制

同济大学学报（自然科学版） 2018年第10期46卷 1410-1415页

作者：李洋邓嘉张新艳同济大学机械与能源工程学院上海201804

基于状态的维护(condition-based maintenance,CBM)方法可以有效降低设备故障率,但维护导致的设备停机会在一定程度上造成系统产量流失.为了减少CBM对生产系统的影响,提出了实时维护决策控制方法.首先,建立基于马尔可夫过程的数学模型... 详细信息

基于状态的维护(condition-based maintenance,CBM)方法可以有效降低设备故障率,但维护导致的设备停机会在一定程度上造成系统产量流失.为了减少CBM对生产系统的影响,提出了实时维护决策控制方法.首先,建立基于马尔可夫过程的数学模型描述系统动态变化.其次,通过计算永久性生产损失量化停机维护对产量的影响.最后,提出了一种控制算法以优化CBM决策.仿真试验结果表明,该模型能恰当描述伯努利生产线的动态变化,且CBM决策控制方法可以减少永久性生产损失、提高整体生产效率.

关键词：基于状态的维护(CBM) 维护控制马尔可夫过程模型动态生产系统永久性生产损失

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数字治理、治理质量与经济增长

统计研究 2023年第7期40卷 123-133页

作者：张晨张新颜山东财经大学财政税务学院

建设数字政府不仅有助于推动国家治理体系和治理能力现代化,而且能够为实现经济高质量发展提供助力。本文关注数字治理与经济增长的关系,从政府治理质量角度探讨政府数字治理能力对经济增长的影响及作用机制。研究发现,第一,数字治理能... 详细信息

建设数字政府不仅有助于推动国家治理体系和治理能力现代化,而且能够为实现经济高质量发展提供助力。本文关注数字治理与经济增长的关系,从政府治理质量角度探讨政府数字治理能力对经济增长的影响及作用机制。研究发现,第一,数字治理能够显著促进经济增长,研究结论具有较强的稳健性。第二,机制检验表明数字治理可以通过提高治理质量(政府效率、监管质量、法治水平和遏制腐败)促进经济增长。第三,异质性分析表明数字治理的经济增长效应具有递减特征,进一步研究发现上述现象源于随着治理水平的提高,数字治理对治理质量的提升作用逐渐减弱。第四,数字治理能够缓解经济系统所遭遇的外部冲击,当负向冲击导致经济下行时,数字治理能够发挥显著的稳增长作用。结合研究发现,本文认为应该通过加大电信基础设施建设和数字人才培养力度、整合碎片化互联网平台和吸收多元化治理主体继续推动数字政府建设,提高政府数字治理水平。

关键词：数字治理治理质量经济增长外部冲击

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基于鱼骨型仓库的拣选路径问题优化

同济大学学报（自然科学版） 2019年第11期47卷 1683-1690页

作者：张新艳周雨晴同济大学机械与能源工程学院

为提高鱼骨型仓库布局下的订单拣选效率,基于拣货路径距离计算模型和以最小化拣货路径总距离为优化目标的拣选路径优化模型,提出一种混沌模拟退火粒子群优化算法,引入混沌理论使粒子更高效地遍历搜寻空间,同时结合了模拟退火算法的概率... 详细信息

为提高鱼骨型仓库布局下的订单拣选效率,基于拣货路径距离计算模型和以最小化拣货路径总距离为优化目标的拣选路径优化模型,提出一种混沌模拟退火粒子群优化算法,引入混沌理论使粒子更高效地遍历搜寻空间,同时结合了模拟退火算法的概率突跳特点使算法在迭代后期仍具有较好的全局寻优能力.最后,通过实例仿真验证了该算法在解决鱼骨型仓库布局拣选路径优化问题上的有效性,并通过与其他算法比较,证明了该算法的先进性,为鱼骨型仓库布局下拣选路径规划问题提供了新的解决思路.

关键词：鱼骨型仓库布局拣货路径优化混沌理论模拟退火粒子群优化算法

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大型直驱永磁风力发电机及其并网运行研究

太阳能学报 2008年第4期29卷 412-416页

作者：张新燕王维庆西安交通大学电气工程学院新疆大学电气工程学院乌鲁木齐830008

为了研究大型直驱式永磁风力发电机控制及其并网后在电力系统中的运行,建立了风速模型、发电机模型,对直驱式永磁风力发电机的工作原理进行了研究,对风力发电机接入电网运行进行了分析,并对最大功率跟踪和桨距角控制进行了研究。采用理... 详细信息

为了研究大型直驱式永磁风力发电机控制及其并网后在电力系统中的运行,建立了风速模型、发电机模型,对直驱式永磁风力发电机的工作原理进行了研究,对风力发电机接入电网运行进行了分析,并对最大功率跟踪和桨距角控制进行了研究。采用理论分析与计算机仿真方法,给出了仿真结果。结果表明,直驱永磁风力发电机在低于额定风速时可以跟踪最大功率,高于额定风速时可以保持额定功率;直驱式永磁风力机对故障电流无贡献,对电网谐波影响很小,几乎不存在闪变问题,对电网频率稳定性无贡献。

关键词：直驱永磁风力发电机控制并网仿真

Adenine Phosphoribosyl Transferase 1 is a Key Enzyme Catalyzing Cytokinin Conversion from Nucleobases to Nucleotides in Arabidopsis

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Molecular Plant 2013年第5期6卷 1661-1672页

作者： xinyan zhang Yutao Chen Xin Lin Xinyu Hong Ying Zhu Wenyang Li Wenrong He Fengying An Hongwei Guo State Key Laboratory of Protein and Plant Gene Research College of Life Sciences Peking-Tsinghua Center for Life Sciences Peking University Life Sciences Building 5 Yi He Yuan Road Haidian Beijing 100871 China

In plants, the cytokinin metabolic processes, including cytokinin biosynthesis, interconversion, inactivation, and degradation, play critical roles in the regulation of cytokinin homeostasis and plant development. Purine meta- bolic enzymes have been implied to catalyze the cytokinin interconversion in previous works. In this study, we report that Adenine Phosphoribosyl Transferase 1 （APT1） is the causal gene of the high-dose cytokinin-resistant mutants. APT1 catalyzes the cytokinin conversion from free bases to nucleotides, and is functionally predominant among the five members of the Arabidopsis Adenine Phosphoribosyl Transferase family. Loss of APT1 activity in plants leads to excess accumulation of cytokinin bases, thus evoking myriad cytokinin-regulated responses, such as delayed leaf senescence, anthocyanin accumulation, and downstream gene expression. Thus, our study defines APT1 as a key metabolic enzyme participating in the cytokinin inactivation by phosphoribosylation.

关键词： APT1 phosphoribosylation cytokinin plant hormone Arabidopsis thaliana.