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Higher ambient temperatures may worsen obstructive sleep apnea:A nationwide smartwatch-based analysis of 6.2 million person-days

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Science Bulletin 2024年第13期69卷 2114-2121页

作者： Anni Li Qingli Zhang Yuan Yao xinlei zhu Cong Liu Yutao Guo Haidong Kan Renjie Chen School of Public Health Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology AssessmentFudan UniversityShanghai 200032China Ministry of Education-Shanghai Key Laboratory of Children’s Environmental Health Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Department of Pulmonary Vessel and Thrombotic Disease Sixth Medical CenterChinese PLA General HospitalBeijing 100048China Institute for Hospital Management Research Chinese PLA General HospitalBeijing 100048China Children’s Hospital of Fudan University National Children’s Medical CenterShanghai 201102China School of Public Health Hengyang Medical SchoolUniversity of South ChinaHengyang 421001China

Obstructive sleep apnea(OSA)is a serious type of sleep disorder that can lead to cardiometabolic and neurocognitive *** utilized smart device-based photoplethysmography technology to collect sleep data from the Chinese population from 2019 to *** lag nonlinear models combined with a generalized nonlinear model or a linear mixed effects model were used to investigate the shortterm associations between daily temperature and indicators of OSA *** included a total of 6,232,056 d of sleep monitoring data from 51,842 participants with moderate to severe risk of OSA from 313 Chinese *** relationships between ambient temperature and OSA exacerbation,apneahypopnea index(AHI),and minimum oxygen saturation(MinSpO_(2))were almost linear and present only on the same *** temperatures were associated with a greater risk of OSA exacerbation,with an 8.4%(95%confidence interval(CI):7.6%–9.3%)increase per 10℃increase in temperature.A 10℃increase in daily temperature corresponded to an AHI increase of 0.70 events/h(95%CI:0.65–0.76)and a MinSpO_(2)decrease of 0.18%(95%CI:0.16%–0.19%).Exposure to elevated temperatures during the night can also lead to adverse *** effects of higher temperatures on OSA severity were stronger among men,participants with a body mass index24 kg/m2,those aged 45 years and older,individuals with a history of hypertension and diabetes,and during the cold *** large-scale,nationwide,longitudinal study provides robust evidence suggesting that higher ambient temperatures may immediately worsen OSA.

关键词： Obstructive sleep apnea Temperature Apnea-hypopnea index Oxygen saturation Smart device

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空间相干结构光场产生、传输及应用研究进展

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四川师范大学学报（自然科学版） 2024年第6期47卷 720-737,F0002页

作者：王飞朱新蕾余佳益苏州大学物理科学与技术学院江苏苏州215006 山东师范大学物理与电子科学学院山东济南250358

空间相干性是光场除了振幅、相位和偏振以外的一个固有属性,它在理解光的干涉、传输、光与物质相互作用等方面起着重要作用.近年来,对空间相干性的研究已经逐渐拓展至对空间相干结构的构建及特性研究,这是因为具有特定空间相干结构分布... 详细信息

空间相干性是光场除了振幅、相位和偏振以外的一个固有属性,它在理解光的干涉、传输、光与物质相互作用等方面起着重要作用.近年来,对空间相干性的研究已经逐渐拓展至对空间相干结构的构建及特性研究,这是因为具有特定空间相干结构分布的光场展现出了新奇的物理效应,如自聚焦、自分裂、自偏移和自整形传输特性等.这些新奇物理效应的许多潜在应用也逐渐被发现,包括在自由空间光通信中降低大气湍流的负面效应、基于空间相干结构的光学加密和鲁棒光信息传输、光学微粒俘获及操纵等.本综述系统地回顾空间相干结构光场的表征方法、理论构建和实验产生方法、在自由空间和湍流介质中的传输特性和相关应用.首先,利用非负正定条件和相干模式分解理论来表示空间相干结构光场的交叉谱密度函数;然后,讨论理论和实验上构建及产生空间相干结构光场的2种不同策略,一种是基于广义范西特-泽尼克定理,另一种是基于相干模分解理论;接下来,概述特定空间相干结构光束在自由空间和湍流大气中的新颖物理特性;最后,介绍空间相干结构光场在降低大气湍流负面效应、光学加密、复杂介质中的鲁棒光信息传输和光学微粒俘获和操纵等方面的应用.光学空间相干结构不仅为光操控提供了新的自由度,产生的空间相干结构光场在诸多领域也展现出了重要应用价值.

关键词：光学相干性空间相干结构光场光场调控

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刘立教授应用和胃平虑法治疗焦虑症(肝胃不和证)经验

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亚太传统医药 2024年第1期20卷 121-124页

作者：侯悦晨刘立朱鑫磊甘肃中医药大学甘肃兰州730000

精神科药物不良反应较多,且不易减药,而中医在治疗精神疾病方面有着极大的优势,因此许多患者在治疗过程中更倾向于服用中药。中医治疗神志病在病因病机的认识上并不统一,有的强调心、有的强调肾。为探讨中医神志病的辨治方法,从和胃平... 详细信息

精神科药物不良反应较多,且不易减药,而中医在治疗精神疾病方面有着极大的优势,因此许多患者在治疗过程中更倾向于服用中药。中医治疗神志病在病因病机的认识上并不统一,有的强调心、有的强调肾。为探讨中医神志病的辨治方法,从和胃平虑法治疗焦虑障碍入手,对焦虑症(肝胃不和证)的病因进行分析,讨论其核心病机,并进一步确定治疗焦虑症(肝胃不和证)的基本原则。焦虑症(肝胃不和证)这类疾病往往以胃部症状的表现为表象,但其辨证论治的核心主要在于精神症状。从精神症状入手在治疗上具有更好的疗效,值得进一步探讨和总结。

关键词：焦虑症经验总结和胃平虑肝胃不和证

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End-on x-ray backlighting experiments for axial diagnostics of wire-array Z-pinch plasma on PPG-1

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Chinese Physics B 2017年第1期26卷 326-332页

作者： Shen Zhao xinlei zhu Huantong Shi Xiaobing Zou Xinxin Wang Department of Electrical Engineering Tsinghua University Beijing 100084 China Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China

An X-pinch axial backlighting system has been designed to quantitatively measure the density distribution of wirearray Z-pinch plasmas. End-on backlighting experiments were carried out on a 200 kA, 100 ns pulsed-power generator（PPG-1） at the Tsinghua University. Compared with side-on backlighting, end-on measurements provide an axial view of the evolution of Z-pinch plasmas. Early stages of 2-, 4-, and 8-wire Z-pinch plasmas were observed via point-projection backlighting radiography with a relatively high success rate. The density distribution of Z-pinch plasma on the r–θ plane was obtained directly from the images with the help of step wedges, and the inward radial velocity was calculated. The ablation rates obtained by X-pinch backlighting experiments are compared in detail with those calculated by the rocket model and the results show consistency.

关键词： X-pinches axial backlighting wire-array Z-pinches

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The effect of the configuration of a single electrode corona discharge on its acoustic characteristics

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Plasma Science and Technology 2017年第7期19卷 57-62页

作者： xinlei zhu Liancheng ZHANG Yifan HUANG Jin WANG Zhen LlU Keping YAN Inslitute of Industrial Ecology and Environment College of Chemical and Biological Engineering Zhejiang University Hangzhou 310028 People＇s Republic of China Dalian Scientific Test and Control Technology Institute Dalian 116013 People＇s Republic of China

A new sparker system based on pulsed spark discharge with a single electrode has already been utilized for oceanic seismic exploration. However, the electro-acoustic energy efficiency of this system is lower than that of arc discharge based systems. A simple electrode structure was investigated in order to improve the electro-acoustic energy efficiency of the spark discharge. Experiments were carried out on an experimental setup with discharge in water driven by a pulsed power source. The voltage-current waveform, acoustic signal and bubble oscillation were recorded when the relative position of the electrode varied. The electro-acoustic energy , efficiency was also calculated. The load voltage had a saltation for the invaginated electrode tip, namely an obvious voltage remnant. The more the electrode tip was invaginated, the larger the pressure peaks and first period became. The results show that electrode recessing into the insulating layer is a simple and effective way to improve the electro-acoustic energy efficiency from 2% to about 4%.

关键词： pulsed discharge in water electro-acoustic efficiency pulsed power plasma soundsource

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Air pollution may increase the sleep apnea severity:A nationwide analysis of smart device-based monitoring

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The Innovation 2023年第6期4卷 69-75页

作者： Qingli Zhang Hong Wang xinlei zhu Anni Li Cong Liu Yutao Guo Haidong Kan Renjie Chen School of Public Health Shanghai Institute of Infectious Disease and BiosecurityKey Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology AssessmentFudan UniversityShanghai 200032China Minitry of Education-Shanghai Key Laboratory of Children's Environmental Health Xinhua Hospital ffliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Sixth Medical Center Chinese PL A General HospitalBejing 100048China Chinese PLA Medical College Beijing 100039China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092China

Obstructive sleep apnea(OSA)can lead to sleep deprivation,accidents,and cardiovascular ***,research on the short-term effects of air pollutants on OSA severity is limited and *** conducted a novel case time series analysis using a nationwide dataset among Huawei smart device users to assess the association between air pollution and OSA severity in a population at moderate-to-severe risk of ***-effects regression models were used to assess the associations between air pollution and the risk of OSA exacerbation,apnea-hypopnea index(AH),and oxygen saturation.A total of 51,842 participants who were at moder-ate-tosevere risk of OSA(mean age[SD]:45.4[11.0],95.5%male)were included,with 6,232,056 person-days of *** as sociations of fine particulate matter,nitrogen dioxide,carbon monoxide,and sulfur dioxide with OSA severity could occur during the sleep period,and last for 2 *** increase of 1 interquartile range in the moving average concentrations of air pollution during the sleep period and the 2 previous days was associated with a 1.14%-4.31%increase in the risk of OSA exacerbation,an increase in AHI by 0.05-0.17 events/h,and a decrease in oxygen saturation(%)by *** exposure-response curves were almost *** associations between air pollutants and OSA were consistently stronger in participants aged 45 years or *** virtue of the smart device-based technology,this largescale,nationwide,longitudinal study provides compelling evidence that short-term exposure to air pollution may worsen sleep *** findings highlight the significance of ongoing efforts to improve air quality in mitigating OSA severity and the relevant disease burden in an aging era.

关键词： severity sleep pollution

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ERF5.1 modulates carotenoid accumulation by interacting with CCD4.1 in Lycium

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Horticulture Research 2023年第12期10卷 190-203页

作者： Jianhua Zhao Yuhui Xu Haoxia Li xinlei zhu Yue Yin Xiyan Zhang Xiaoya Qin Jun Zhou Linyuan Duan Xiaojie Liang Ting Huang Bo Zhang Ru Wan Zhigang Shi Youlong Cao Wei An National Wolfberry Engineering Research Center/Wolfberry Science Research Institute Ningxia Academy of Agriculture and Forestry SciencesYinchuan750002China Institute of Forestry and Grassland Ecology Ningxia Academy of Agriculture and Forestry SciencesYinchuan750002China College of Biological Science&Engineering North Minzu UniversityYinchuan 750021China

Carotenoids are important natural pigments and have medical and health functions for *** cleavage dioxygenase 4(CCD4)and ethylene responsive factor(ERF)participate in carotenoid metabolism,but their roles in Lycium have not been ***,we annotated LbCCDs from the Lycium reference genome and found that LbCCD4.1 expression was significantly correlated with the carotenoid metabolites during Lycium five fruit developmental ***-expression of LbCCD4.1 in NQ’s leaves resulted in a series of significantly lower contents of carotenoid metabolites,includingβ-carotene andβ-***,LbERF5.1,a transcription factor belonging to the ERF family that was located in the nucleus,was *** reductions in the carotenoids,especially lutein,violaxanthin and their derivatives,were observed in over-expressing ERF5.1 transgenic NQ’s ***-expression or virus-induced gene silencing of LbERF5.1 in NQ’s leaves induced a consistent up-or down-expression,respectively,of ***,yeast one-hybrid and dual-luciferase reporter assays showed that ERF5.1 interacted with the promoter of CCD4.1 to increase its expression,and LbERF5.1 could bind to any one of the three predicted binding sites in the promoter of LbCCD4.1.A transcriptome analysis of LbERF5.1 and LbCCD4.1 over-expressed lines showed similar global transcript expression,and geranylgeranyl diphosphate synthase,phytoene synthase,lycopeneδ-cyclase cytochrome,cytochrome P450-type monooxygenase 97A,cytochrome P450-type monooxygenase 97C,and zeaxanthin epoxidase in the carotenoid biosynthesis pathway were differentially *** summary,we uncovered a novel molecular mechanism of carotenoid accumulation that involved an interaction between ERF5.1 and CCD4.1,which may be used to enhance carotenoid in Lycium.

关键词： metabolism expressing Lycium

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Noniterative spatially partially coherent diffractive imaging using pinhole array mask

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Advanced Photonics 2019年第1期1卷 84-91页

作者： Xingyuan Lu Yifeng Shao Chengliang Zhao Sander Konijnenberg xinlei zhu Ying Tang Yangjian Cai HPaul Urbach Soochow University School of Physical Science and TechnologySuzhouChina Delft University of Technology Optics Research GroupDelftNetherlands Shandong Normal University School of Physics and ElectronicsCenter of Light Manipulation and ApplicationJinanChina

We propose and experimentally demonstrate a noniterative diffractive imaging method for reconstructing the complex-valued transmission function of an object illuminated by spatially partially coherent light from the far-field diffraction *** method is based on a pinhole array mask,which is specially designed such that the correlation function in the mask plane can be obtained directly by inverse Fourier transforming the diffraction *** to the traditional iterative diffractive imaging methods using spatially partially coherent illumination,our method is noniterative and robust to the degradation of the spatial coherence of the *** addition to diffractive imaging,the proposed method can also be applied to spatial coherence property characterization,e.g.,free-space optical communication and optical coherence singularity measurement.

关键词： partial coherence coherent diffractive imaging noniterative method pinhole array mask

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Adaptive uncertainty and disturbance estimator based model reference adaptive dynamic sliding mode control for overhead cranes

Adaptive uncertainty and disturbance estimator based model r...

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第40届中国控制会议

作者： Qiang Hu Weimin Xu Xianxian Xu Zhiteng You xinlei zhu Key of laboratory of marine technology and control engineering Ministry of communicationsShanghai Maritime university

This paper proposes a model reference adaptive dynamic sliding mode control（MRASMC） scheme with an adaptive uncertainty and disturbance estimator（AUDE）, the scheme is then applied to two-dimensional overhead cranes control with uncertainties, to ensure the payload can be transported to the desired position rapidly while its swing angle can be eliminated simultaneously. Firstly, a desired reference model for improving transient performance is designed. More specifically, a novel chattering-free reaching law along with adaptive integral sliding mode surface is designed to achieve fast convergence of system state variable errors, thereby improving system transient performance. In addition, the designed novel moving sliding mode surface can adjust its slope in real time according to the state variable errors. Moreover, to suppress the uncertainties occurring in overhead cranes system, such as matched disturbances, unmatched disturbances. An adaptive uncertainty and disturbance estimator（AUDE） technique is employed to estimate these disturbances, then the estimated disturbances are taken as feedforward control term to overcome the chattering phenomenon. The stability and convergence of the control system is strictly analyzed using Lyapunov theory. Simulation results are presented to illustrate the effectiveness of the proposed controller.

关键词： overhead crane model reference adaptive adaptive integral sliding mode surface chattering-free reaching law moving sliding mode surface adaptive uncertainty and disturbance estimator unmatched disturbance

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An Adaptive Integral Sliding Mode Control method for Overhead Cranes with monocular visual feedback

An Adaptive Integral Sliding Mode Control method for Overhea...

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第40届中国控制会议

作者： Zhiteng You Weimin Xu Xianxian Xu xinlei zhu Qiang Hu Key Laboratory of Marine Technology and Control Engineering Ministry of CommunicationsShanghai Maritime University

In this paper, an overhead crane control scheme based on visual feedback is developed to restrain the swing angle of payload and to transport the payload to a desired position rapidly and accurately. A monocular camera system, a modified mean shift algorithm and a minimum area circle method are employed to obtain payload swing angle. Data fusion is proposed to improve the accuracy of payload swing angle which is used as the feedback value of the overhead crane controller. Then, an adaptive gain integral sliding mode controller for the overhead crane is proposed to realize anti sway and positioning control,while eliminating the influence of image processing time and information transmission time, that is, the parameters of the suggested controller may be adjusted according to the delay time. This method can enhance the robustness of the crane control system to time delay caused by image calculation and information transmission and disturbance. The stability of the control system is analyzed using Lyapunov theory. The effectiveness of the proposed control scheme is verified through simulation.

关键词： overhead crane monocular visual-based sliding model control adaptive control image processing data fusion

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